Research Topics
| K WalkerSummaryAffiliation: Novartis Institutes for BioMedical Research Publications
| Collaborators |
Detail Information
Publications
Metabotropic glutamate receptor subtype 5 (mGlu5) and nociceptive function. I. Selective blockade of mGlu5 receptors in models of acute, persistent and chronic painK Walker
Nervous System Research, Novartis Pharma AG, CH 4002, Basle, Switzerland
Neuropharmacology 40:1-9. 2001..In contrast to its effects in models of inflammatory pain, MPEP did not produce significant reversal of mechanical hyperalgesia in a rat model of neuropathic pain...
mGlu5 receptors and nociceptive function II. mGlu5 receptors functionally expressed on peripheral sensory neurones mediate inflammatory hyperalgesiaK Walker
Novartis Pharma AG, Nervous System Research, CH 4002, Basle, Switzerland
Neuropharmacology 40:10-9. 2001..These results suggest that mGlu5 receptors expressed on the peripheral terminals of sensory neurones are involved in nociceptive processes and contribute to the hyperalgesia associated with inflammation...
