P M Steed

Summary

Affiliation: Novartis Institutes for BioMedical Research

Publications

  1. ncbi request reprint Phospholipase D regulation by a physical interaction with the actin-binding protein gelsolin
    P M Steed
    Research Department, CIBA Pharmaceutical, Summit, New Jersey 07901, USA
    Biochemistry 35:5229-37. 1996
  2. pmc Characterization of recombinant human cathepsin B expressed at high levels in baculovirus
    P M Steed
    Research Department, Novartis Pharmaceuticals, Summit, New Jersey 07901, USA
    Protein Sci 7:2033-7. 1998
  3. ncbi request reprint Characterization of human PLD2 and the analysis of PLD isoform splice variants
    P M Steed
    Novartis Institute for Biomedical Research, Summit, New Jersey 07901, USA
    FASEB J 12:1309-17. 1998
  4. ncbi request reprint Intracellular signaling by phospholipase D as a therapeutic target
    P M Steed
    Novartis Institute for Biomedical Research, Summit, New Jersey 07901, USA
    Curr Pharm Biotechnol 2:241-56. 2001

Collaborators

Detail Information

Publications4

  1. ncbi request reprint Phospholipase D regulation by a physical interaction with the actin-binding protein gelsolin
    P M Steed
    Research Department, CIBA Pharmaceutical, Summit, New Jersey 07901, USA
    Biochemistry 35:5229-37. 1996
    ....
  2. pmc Characterization of recombinant human cathepsin B expressed at high levels in baculovirus
    P M Steed
    Research Department, Novartis Pharmaceuticals, Summit, New Jersey 07901, USA
    Protein Sci 7:2033-7. 1998
    ..Further, we demonstrate that the manner of expression and purification of this enzyme has profound effects on its kinetic and physical parameters...
  3. ncbi request reprint Characterization of human PLD2 and the analysis of PLD isoform splice variants
    P M Steed
    Novartis Institute for Biomedical Research, Summit, New Jersey 07901, USA
    FASEB J 12:1309-17. 1998
    ..The presence of Pleckstrin homology domains in the PLDs resolves several contradictory observations regarding PLD regulation and the domain structure of the proteins...
  4. ncbi request reprint Intracellular signaling by phospholipase D as a therapeutic target
    P M Steed
    Novartis Institute for Biomedical Research, Summit, New Jersey 07901, USA
    Curr Pharm Biotechnol 2:241-56. 2001
    ..The utility of targeting PLD signaling for the treatment of acute/chronic inflammation and other indications is discussed in light of these data...