Affiliation: Novartis Institutes for BioMedical Research
- SH3GLB, a new endophilin-related protein family featuring an SH3 domainB Pierrat
Molecular and Cell Biology Expert Laboratory, Novartis Pharma Research, Basel, CH 4002, Switzerland
Genomics 71:222-34. 2001..SH3GLB1 and SH3GLB2 do not significantly influence the onset and time course of Bax-mediated apoptosis in HeLa or 293T cells...
- Uncoupling proteins 2 and 3 interact with members of the 14.3.3 familyB Pierrat
Novartis Pharma Inc, Basle, Switzerland
Eur J Biochem 267:2680-7. 2000..3.3 proteins potentiated the inhibitory effect of UCP3 overexpression on cell growth. These findings suggest that 14.3.3 proteins could be involved in the targeting of UCPs to the mitochondria...
- The 5' untranslated region of the PPR1 regulatory gene dictates rapid mRNA decay in yeastB Pierrat
, Strasbourg, France
Gene 131:43-51. 1993..Fusion of this PPR1 5'-UTR to the URA3 coding region was sufficient to destabilize the chimeric mRNA. We conclude that the PPR1 5'-UTR contains sequence(s) that can promote rapid mRNA decay in yeast...
- Retinoic acid receptors interact physically and functionally with the T:G mismatch-specific thymine-DNA glycosylaseS Um
Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM ULP, College de France, BP 163, 67404 Illkirch Cedex, France
J Biol Chem 273:20728-36. 1998..In vitro, TDG enhanced RXR and RXR/RAR binding to their response elements. These data indicate that TDG is not only a repair enzyme, but could also function in the control of transcription...