Research Topics
| Vincent MalaterreSummaryAffiliation: Novartis Institutes for BioMedical Research Publications
|
Detail Information
Publications
Evaluation of the tablet core factors influencing the release kinetics and the loadability of push-pull osmotic systemsVincent Malaterre
Novartis Pharma AG, Technical R and D, Basel, Switzerland
Drug Dev Ind Pharm 35:433-9. 2009..High osmotic agent proportions and viscous-grade polymers were recommended to formulate high drug loads up to 20% without losing both the release completeness and the zero-order drug release kinetics...
Terahertz pulsed imaging, a novel process analytical tool to investigate the coating characteristics of push-pull osmotic systemsVincent Malaterre
Novartis Pharma AG, Technical R and D, Basel, Switzerland
Eur J Pharm Biopharm 74:21-5. 2010..Based on the results, the potential benefits of implementing 3D-TPI as quality control analytical tool were discussed...
Approach to design push-pull osmotic pumpsVincent Malaterre
Novartis Pharma AG, Technical R and D, Basel, Switzerland
Int J Pharm 376:56-62. 2009..A mathematical approach was developed to predict the drug delivery kinetics varying the PPOP controlling factors and helps to more efficiently design PPOP...
Benchtop-magnetic resonance imaging (BT-MRI) characterization of push-pull osmotic controlled release systemsVincent Malaterre
Novartis Pharma AG, Technical R and D, Fabrikstrasse 2, CH 4056 Basel, Switzerland
J Control Release 133:31-6. 2009..MRI is therefore a powerful tool to get insights on the drug delivery mechanism of push-pull osmotic systems, which enable a more efficient optimization of such formulations...
Oral osmotically driven systems: 30 years of development and clinical useVincent Malaterre
Novartis Pharma AG, Technical R and D, Basel, Switzerland School of Pharmaceutical Sciences, University of Geneva Lausanne, Geneva, Switzerland
Eur J Pharm Biopharm 73:311-23. 2009..Special attention is paid to safety given the controversial case study of Osmosin. Overall, oral osmotically driven systems appear to be a promising technology for product life-cycle strategies...
