Tatsuhiko Kasaoka

Summary

Affiliation: Novartis Institutes for BioMedical Research

Publications

  1. doi request reprint Matrix metalloproteinase inhibitor, MMI270 (CGS27023A) inhibited hematogenic metastasis of B16 melanoma cells in both experimental and spontaneous metastasis models
    Tatsuhiko Kasaoka
    Tsukuba Research Institute, Novartis Pharma K K, Ohkubo 8, Tsukuba shi, Ibaraki 300 2611, Japan
    Clin Exp Metastasis 25:827-34. 2008
  2. ncbi request reprint Silencing of focal adhesion kinase by tumor direct injection of small interfering RNA decreases in vivo tumor growth
    Kae Tsutsumi
    Tsukuba Research Institute, Novartis Pharma, KK, Tsukuba shi, Ibaraki, Japan
    Cancer Biol Ther 8:1292-9. 2009
  3. ncbi request reprint Tumor growth inhibition by synthetic and expressed siRNA targeting focal adhesion kinase
    Kae Tsutsumi
    Tsukuba Research Institute, Novartis Pharma K K, Tsukuba shi, Ibaraki 300 2611, Japan
    Int J Oncol 33:215-24. 2008

Collaborators

  • Kae Tsutsumi
  • Toshiyuki Honda
  • Motowo Nakajima
  • Takeshi Yamaura
  • Hyi Man Park
  • Hiroko Nishiyama

Detail Information

Publications3

  1. doi request reprint Matrix metalloproteinase inhibitor, MMI270 (CGS27023A) inhibited hematogenic metastasis of B16 melanoma cells in both experimental and spontaneous metastasis models
    Tatsuhiko Kasaoka
    Tsukuba Research Institute, Novartis Pharma K K, Ohkubo 8, Tsukuba shi, Ibaraki 300 2611, Japan
    Clin Exp Metastasis 25:827-34. 2008
    ....
  2. ncbi request reprint Silencing of focal adhesion kinase by tumor direct injection of small interfering RNA decreases in vivo tumor growth
    Kae Tsutsumi
    Tsukuba Research Institute, Novartis Pharma, KK, Tsukuba shi, Ibaraki, Japan
    Cancer Biol Ther 8:1292-9. 2009
    ..In addition, we showed that ERK is the critical MAP kinase in the signaling pathway down stream of FAK in in vivo proliferation of 4T1 tumor cells...
  3. ncbi request reprint Tumor growth inhibition by synthetic and expressed siRNA targeting focal adhesion kinase
    Kae Tsutsumi
    Tsukuba Research Institute, Novartis Pharma K K, Tsukuba shi, Ibaraki 300 2611, Japan
    Int J Oncol 33:215-24. 2008
    ..These results support our hypothesis that FAK plays a crucial role in tumor formation and growth in vivo by regulation of cell adhesion and proliferation by FAK-dependent signals...