Jean Pierre Evenou
Affiliation: Novartis Institutes for BioMedical Research
- The potent protein kinase C-selective inhibitor AEB071 (sotrastaurin) represents a new class of immunosuppressive agents affecting early T-cell activationJean Pierre Evenou
Novartis Institute for Biomedical Research, WSJ 386 5 27, CH 4002 Basel, Switzerland
J Pharmacol Exp Ther 330:792-801. 2009..The mode of action of AEB071 is different from that of calcineurin inhibitors, and AEB071 and cyclosporine A seem to have complementary effects on T-cell signaling pathways...