PHILIP DORMITZER

Summary

Affiliation: Novartis Institutes for BioMedical Research

Publications

  1. doi request reprint Structure-based antigen design: a strategy for next generation vaccines
    Philip R Dormitzer
    Novartis Vaccines and Diagnostics, Inc, 350 Massachusetts Ave, Cambridge, MA 02139, USA
    Trends Biotechnol 26:659-67. 2008
  2. doi request reprint Synthetic generation of influenza vaccine viruses for rapid response to pandemics
    Philip R Dormitzer
    Novartis Vaccines and Diagnostics, Cambridge, MA 02139, USA
    Sci Transl Med 5:185ra68. 2013
  3. doi request reprint New technologies for influenza vaccines
    Philip R Dormitzer
    Novartis Vaccines and Diagnostics, Cambridge, MA, USA
    Hum Vaccin Immunother 8:45-58. 2012
  4. pmc Mutations at positions 186 and 194 in the HA gene of the 2009 H1N1 pandemic influenza virus improve replication in cell culture and eggs
    Pirada Suphaphiphat
    Novartis Vaccines and Diagnostics, Cambridge, MA, USA
    Virol J 7:157. 2010
  5. doi request reprint Influenza vaccine immunology
    Philip R Dormitzer
    Novartis Vaccines and Diagnostics, Siena, Italy
    Immunol Rev 239:167-77. 2011
  6. ncbi request reprint Building an insurance against modern pandemics
    Rino Rappuoli
    Novartis Vaccines and Diagnostics, Via Fiorentina 1, 53100 Siena, Italy
    Curr Opin Investig Drugs 11:126-30. 2010
  7. pmc High-resolution molecular and antigen structure of the VP8* core of a sialic acid-independent human rotavirus strain
    Nilah Monnier
    Harvard College, Cambridge, MA 02138, USA
    J Virol 80:1513-23. 2006

Research Grants

  1. Rotavirus VP4: Structure and function
    PHILIP DORMITZER; Fiscal Year: 2003
  2. Rotavirus VP4: Structure and function
    PHILIP DORMITZER; Fiscal Year: 2006

Detail Information

Publications7

  1. doi request reprint Structure-based antigen design: a strategy for next generation vaccines
    Philip R Dormitzer
    Novartis Vaccines and Diagnostics, Inc, 350 Massachusetts Ave, Cambridge, MA 02139, USA
    Trends Biotechnol 26:659-67. 2008
    ..Understanding the structural basis for immunogenicity and immunodominance will allow us to improve vaccine efficacy and broaden the range of vaccine-preventable diseases...
  2. doi request reprint Synthetic generation of influenza vaccine viruses for rapid response to pandemics
    Philip R Dormitzer
    Novartis Vaccines and Diagnostics, Cambridge, MA 02139, USA
    Sci Transl Med 5:185ra68. 2013
    ....
  3. doi request reprint New technologies for influenza vaccines
    Philip R Dormitzer
    Novartis Vaccines and Diagnostics, Cambridge, MA, USA
    Hum Vaccin Immunother 8:45-58. 2012
    ..This review describes some of the new approaches to influenza immunization that are the subjects of active research and development...
  4. pmc Mutations at positions 186 and 194 in the HA gene of the 2009 H1N1 pandemic influenza virus improve replication in cell culture and eggs
    Pirada Suphaphiphat
    Novartis Vaccines and Diagnostics, Cambridge, MA, USA
    Virol J 7:157. 2010
    ..Thus, we have demonstrated that molecular cloning of members of a quasispecies can help in selection of seed viruses for vaccine manufacture...
  5. doi request reprint Influenza vaccine immunology
    Philip R Dormitzer
    Novartis Vaccines and Diagnostics, Siena, Italy
    Immunol Rev 239:167-77. 2011
    ..The MF59 adjuvant broadens the distribution of B-cell epitopes recognized on HA and NA following immunization...
  6. ncbi request reprint Building an insurance against modern pandemics
    Rino Rappuoli
    Novartis Vaccines and Diagnostics, Via Fiorentina 1, 53100 Siena, Italy
    Curr Opin Investig Drugs 11:126-30. 2010
    ..The lessons learned from the 2009 H1N1 pandemic are of paramount importance to develop more effective preparations against future pandemics...
  7. pmc High-resolution molecular and antigen structure of the VP8* core of a sialic acid-independent human rotavirus strain
    Nilah Monnier
    Harvard College, Cambridge, MA 02138, USA
    J Virol 80:1513-23. 2006
    ..The distribution of escape mutations on the DS-1 VP8* core indicates that neutralizing antibodies that recognize VP8* of human rotavirus strains may bind a conformation of the spike that differs from those observed to date...

Research Grants4

  1. Rotavirus VP4: Structure and function
    PHILIP DORMITZER; Fiscal Year: 2003
    ..abstract_text> ..
  2. Rotavirus VP4: Structure and function
    PHILIP DORMITZER; Fiscal Year: 2006
    ..abstract_text> ..