H Wangensteen

Summary

Affiliation: University of Oslo
Country: Norway

Publications

  1. request reprint
    Wangensteen H, Dang H, Uddin S, Alamgir M, Malterud K. Antioxidant and antimicrobial effects of the mangrove tree Heritiera fomes. Nat Prod Commun. 2009;4:371-6 pubmed
    ..The bark extracts showed antibacterial activities against K. rhizophilia, S. aureus, B. subtilis and P. aeruginosa, as well. No toxicity was observed in the brine shrimp assay...
  2. Seethapathy G, Tadesse M, Urumarudappa S, V Gunaga S, Vasudeva R, Malterud K, et al. Authentication of Garcinia fruits and food supplements using DNA barcoding and NMR spectroscopy. Sci Rep. 2018;8:10561 pubmed publisher
    ..Furthermore the study demonstrates that DNA barcoding and NMR could be effectively used as a regulatory tool to authenticate Garcinia fruit rinds and food supplements. ..
  3. Overgaard H, Sirisopa P, Mikolo B, Malterud K, Wangensteen H, Zou Y, et al. Insecticidal activities of bark, leaf and seed extracts of Zanthoxylum heitzii against the African malaria vector Anopheles gambiae. Molecules. 2014;19:21276-90 pubmed publisher
    ..Overall, there was no significant difference between the responses of the three mosquito strains to Z. heitzii extracts, indicating no cross resistance with conventional pesticides. ..
  4. Moussavi N, Malterud K, Mikolo B, Dawes D, Chandre F, Corbel V, et al. Identification of chemical constituents of Zanthoxylum heitzii stem bark and their insecticidal activity against the malaria mosquito Anopheles gambiae. Parasit Vectors. 2015;8:503 pubmed publisher
    ..The toxicity of Z. heitzii bark hexane extract to An. gambiae is mostly due to pellitorine, although interactions between pellitorine and other, inactive constituents may enhance the activity of the extract. ..
  5. Wangensteen H, Diallo D, Paulsen B. Medicinal plants from Mali: Chemistry and biology. J Ethnopharmacol. 2015;176:429-37 pubmed publisher
    ..Our studies showed that ethnopharmacological information is important for the determination of screening and chemical methods to be used for studies of plants used in traditional medicine. ..
  6. Nguyen T, Rusten A, Bugge M, Malterud K, Diallo D, Paulsen B, et al. Flavonoids, gallotannins and ellagitannins in Syzygium guineense and the traditional use among Malian healers. J Ethnopharmacol. 2016;192:450-458 pubmed publisher
    ..The high content of biologically active polyphenols might be important for medicinal effects of this plant and might give a rationale for the widespread usage of S. guineense in Mali. ..
  7. Goodman C, Austarheim I, Mollard V, Mikolo B, Malterud K, McFadden G, et al. Natural products from Zanthoxylum heitzii with potent activity against the malaria parasite. Malar J. 2016;15:481 pubmed publisher
    ..These compounds may present good leads for development of novel anti-malarials and add to the understanding of the chemical basis of the anti-parasitic activity in these classes of natural product. ..
  8. Ho G, Kase E, Wangensteen H, Barsett H. Effect of Phenolic Compounds from Elderflowers on Glucose- and Fatty Acid Uptake in Human Myotubes and HepG2-Cells. Molecules. 2017;22: pubmed publisher
    ..Elderflower might therefore be valuable as a functional food against diabetes. ..
  9. Wangensteen H, Ho G, Tadesse M, Miles C, Moussavi N, Mikolo B, et al. A new benzophenanthridine alkaloid and other bioactive constituents from the stem bark of Zanthoxylum heitzii. Fitoterapia. 2016;109:196-200 pubmed publisher
    ..Low cytotoxicity against a macrophage cell line was observed. ..

More Information

Publications14

  1. Austarheim I, Pham A, Nguyen C, Zou Y, Diallo D, Malterud K, et al. Antiplasmodial, anti-complement and anti-inflammatory in vitro effects of Biophytum umbraculum Welw. traditionally used against cerebral malaria in Mali. J Ethnopharmacol. 2016;190:159-64 pubmed publisher
    ..However, clinical trials are necessary to evaluate the activity due to the complex pathogenesis of cerebral malaria. ..
  2. Ho G, Wangensteen H, Barsett H. Elderberry and Elderflower Extracts, Phenolic Compounds, and Metabolites and Their Effect on Complement, RAW 264.7 Macrophages and Dendritic Cells. Int J Mol Sci. 2017;18: pubmed publisher
    ..Only 4-methylcatechol was cytotoxic at the highest tested concentration (100 µM). Elderberry and elderflower constituents may possess inflammatory modulating activity, which increases their nutritional value. ..
  3. Wangensteen H, Phan T, Rise F, Halvorsen T, Malterud K. New labdane diterpenes from Solidago canadensis. Nat Prod Res. 2012;26:1348-54 pubmed publisher
    ..The known labdane diterpenes deoxysolidagenone (1), solidagenone (2) and 15,16-epoxy-labdane-7,13-diene-6,15-dione (4) were also isolated. Chemical structures were determined using 1D and 2D NMR techniques and MS analysis...
  4. Wangensteen H, Klarpås L, Alamgir M, Samuelsen A, Malterud K. Can scientific evidence support using Bangladeshi traditional medicinal plants in the treatment of diarrhoea? A review on seven plants. Nutrients. 2013;5:1757-800 pubmed publisher
    ..The leaves of P. pinnata also show potential. We suggest these plants should be exploited further as possible traditional herbal remedies against diarrhoea including studies on efficacy, optimal dosage and safety. ..
  5. Ho G, Nguyen T, Kase E, Tadesse M, Barsett H, Wangensteen H. Enhanced Glucose Uptake in Human Liver Cells and Inhibition of Carbohydrate Hydrolyzing Enzymes by Nordic Berry Extracts. Molecules. 2017;22: pubmed publisher
    ..These results increase the value of these berries as a component of a healthy Nordic diet and have a potential benefit against diabetes. ..