Stein Emil Vollset

Summary

Affiliation: University of Bergen
Country: Norway

Publications

  1. ncbi Folate supplementation and twin pregnancies
    Stein Emil Vollset
    Department of Public Health and Primary Health Care, Section for Epidemiology and Medical Statistics, Locus for Registry Based Epidemiology, University of Bergen, Bergen, Norway
    Epidemiology 16:201-5. 2005
  2. ncbi The association of gastric cancer risk with plasma folate, cobalamin, and methylenetetrahydrofolate reductase polymorphisms in the European Prospective Investigation into Cancer and Nutrition
    Stein Emil Vollset
    LOCUS for Homocysteine and Related Vitamins, Institute of Medicine, University of Bergen, Bergen, Norway
    Cancer Epidemiol Biomarkers Prev 16:2416-24. 2007
  3. ncbi Does the southern European cardiovascular mortality advantage extend to total mortality? 50-year trends in death risks between 40 and 70 years of age in Western European men and women
    Stein Emil Vollset
    Department of Public Health and Primary Health Care, University of Bergen, Norwegian Institute of Public Health, Norway
    Scand J Public Health 38:127-34. 2010
  4. ncbi Vitamins B2 and B6 and genetic polymorphisms related to one-carbon metabolism as risk factors for gastric adenocarcinoma in the European prospective investigation into cancer and nutrition
    Simone J P M Eussen
    LOCUS for Homocysteine and Related Vitamins, Department of Pharmacology, Institute of Medicine, University of Bergen, and Haukeland University Hospital, Bergen, Norway
    Cancer Epidemiol Biomarkers Prev 19:28-38. 2010
  5. ncbi Plasma folate, related genetic variants, and colorectal cancer risk in EPIC
    Simone J P M Eussen
    LOCUS for Homocysteine and Related Vitamins, Institute of Medicine, Section for Pharmacology, Department of Internal Medicine, University of Bergen, and Haukeland University Hospital, 5021 Laboratory Building, 9th Floor, Bergen, Norway
    Cancer Epidemiol Biomarkers Prev 19:1328-40. 2010
  6. ncbi The methylenetetrahydrofolate reductase 677C-->T polymorphism as a modulator of a B vitamin network with major effects on homocysteine metabolism
    Steinar Hustad
    The Hormone Laboratory, Haukeland University Hospital, Bergen, Norway
    Am J Hum Genet 80:846-55. 2007
  7. ncbi Plasma vitamins B2, B6, and B12, and related genetic variants as predictors of colorectal cancer risk
    Simone J P M Eussen
    LOCUS for Homocysteine and Related Vitamins, Institute of Medicine, University of Bergen, and Haukeland University Hospital, Bergen, Norway
    Cancer Epidemiol Biomarkers Prev 19:2549-61. 2010
  8. ncbi Modulation of the homocysteine-betaine relationship by methylenetetrahydrofolate reductase 677 C->t genotypes and B-vitamin status in a large-scale epidemiological study
    Pal I Holm
    Hormone Laboratory, Haukeland University Hospital, Section for Pharmacology, Institute of Medicine, Armauer Hanssens hus, University of Bergen, 5021 Bergen, Norway
    J Clin Endocrinol Metab 92:1535-41. 2007
  9. ncbi Dietary predictors of plasma total homocysteine in the Hordaland Homocysteine Study
    Svetlana V Konstantinova
    Section of Epidemiology and Medical Statistics, Department of Public Health and Primary Health Care, University of Bergen, Kalfarveien, 31, Bergen, Norway
    Br J Nutr 98:201-10. 2007
  10. ncbi Biomarkers related to one-carbon metabolism as potential risk factors for distal colorectal adenomas
    Stefan de Vogel
    Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway
    Cancer Epidemiol Biomarkers Prev 20:1726-35. 2011

Detail Information

Publications62

  1. ncbi Folate supplementation and twin pregnancies
    Stein Emil Vollset
    Department of Public Health and Primary Health Care, Section for Epidemiology and Medical Statistics, Locus for Registry Based Epidemiology, University of Bergen, Bergen, Norway
    Epidemiology 16:201-5. 2005
    ..For this purpose several countries add folate to the flour. Therefore, it is important to monitor possible adverse effects of this B vitamin. We have assessed the effect of folate on twin pregnancies...
  2. ncbi The association of gastric cancer risk with plasma folate, cobalamin, and methylenetetrahydrofolate reductase polymorphisms in the European Prospective Investigation into Cancer and Nutrition
    Stein Emil Vollset
    LOCUS for Homocysteine and Related Vitamins, Institute of Medicine, University of Bergen, Bergen, Norway
    Cancer Epidemiol Biomarkers Prev 16:2416-24. 2007
    ..However, we observed increased gastric cancer risk at low cobalamin levels that was most likely due to compromised cobalamin status in atrophic gastritis preceding gastric cancer...
  3. ncbi Does the southern European cardiovascular mortality advantage extend to total mortality? 50-year trends in death risks between 40 and 70 years of age in Western European men and women
    Stein Emil Vollset
    Department of Public Health and Primary Health Care, University of Bergen, Norwegian Institute of Public Health, Norway
    Scand J Public Health 38:127-34. 2010
    ..To study 50-year mortality trends in men and women of northern and southern Western Europe...
  4. ncbi Vitamins B2 and B6 and genetic polymorphisms related to one-carbon metabolism as risk factors for gastric adenocarcinoma in the European prospective investigation into cancer and nutrition
    Simone J P M Eussen
    LOCUS for Homocysteine and Related Vitamins, Department of Pharmacology, Institute of Medicine, University of Bergen, and Haukeland University Hospital, Bergen, Norway
    Cancer Epidemiol Biomarkers Prev 19:28-38. 2010
    ..In summary, results from this large European cohort study showed an inverse association between vitamin B2 and GC risk, which is borderline significant, and a significant inverse association between vitamin B6 and GC risk...
  5. ncbi Plasma folate, related genetic variants, and colorectal cancer risk in EPIC
    Simone J P M Eussen
    LOCUS for Homocysteine and Related Vitamins, Institute of Medicine, Section for Pharmacology, Department of Internal Medicine, University of Bergen, and Haukeland University Hospital, 5021 Laboratory Building, 9th Floor, Bergen, Norway
    Cancer Epidemiol Biomarkers Prev 19:1328-40. 2010
    ..We investigate the associations between plasma folate, several relevant folate-related polymorphisms, and CRC risk within the large European Prospective Investigation into Cancer and Nutrition cohort...
  6. ncbi The methylenetetrahydrofolate reductase 677C-->T polymorphism as a modulator of a B vitamin network with major effects on homocysteine metabolism
    Steinar Hustad
    The Hormone Laboratory, Haukeland University Hospital, Bergen, Norway
    Am J Hum Genet 80:846-55. 2007
    ..Individuals with the TT genotype were particularly sensitive to the status of several B vitamins and might be candidates for personalized nutritional recommendations...
  7. ncbi Plasma vitamins B2, B6, and B12, and related genetic variants as predictors of colorectal cancer risk
    Simone J P M Eussen
    LOCUS for Homocysteine and Related Vitamins, Institute of Medicine, University of Bergen, and Haukeland University Hospital, Bergen, Norway
    Cancer Epidemiol Biomarkers Prev 19:2549-61. 2010
    ..Although associations with folate have frequently been studied, studies on other plasma vitamins B2, B6, and B12 and colorectal cancer are scarce or inconclusive...
  8. ncbi Modulation of the homocysteine-betaine relationship by methylenetetrahydrofolate reductase 677 C->t genotypes and B-vitamin status in a large-scale epidemiological study
    Pal I Holm
    Hormone Laboratory, Haukeland University Hospital, Section for Pharmacology, Institute of Medicine, Armauer Hanssens hus, University of Bergen, 5021 Bergen, Norway
    J Clin Endocrinol Metab 92:1535-41. 2007
    ....
  9. ncbi Dietary predictors of plasma total homocysteine in the Hordaland Homocysteine Study
    Svetlana V Konstantinova
    Section of Epidemiology and Medical Statistics, Department of Public Health and Primary Health Care, University of Bergen, Kalfarveien, 31, Bergen, Norway
    Br J Nutr 98:201-10. 2007
    ..In conclusion, food items rich in B-vitamins and with a low content of fat and sugar were related to lower tHcy levels. Eggs, chicken, non-processed meat, fish and milk were inversely associated with tHcy...
  10. ncbi Biomarkers related to one-carbon metabolism as potential risk factors for distal colorectal adenomas
    Stefan de Vogel
    Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway
    Cancer Epidemiol Biomarkers Prev 20:1726-35. 2011
    ..However, plasma folate and vitamins B2 and B12 have inconsistently been associated with colorectal cancer risk, and there have been no previous studies relating plasma concentrations of methionine, choline, and betaine to this outcome...
  11. ncbi Plasma total homocysteine level and bone mineral density: the Hordaland Homocysteine Study
    Clara Gram Gjesdal
    Department of Public Health and Primary Health Care, Institute of Medicine, University of Bergen, and Department of Rheumatology, Haukeland University Hospital, Norway
    Arch Intern Med 166:88-94. 2006
    ..We examined the association of hip BMD with levels of plasma tHcy, folate, and vitamin B12 and the methylenetetrahydrofolate reductase (MTHFR) 677C-->T and 1298A-->C polymorphisms...
  12. ncbi Large-scale population-based metabolic phenotyping of thirteen genetic polymorphisms related to one-carbon metabolism
    Ase Fredriksen
    LOCUS for Homocysteine and Related Vitamins, University of Bergen, Bergen, Norway
    Hum Mutat 28:856-65. 2007
    ..2756A>G (tHcy), BHMT c.716G>A (DMG), CBS c.844_845ins68 (tHcy, betaine), CBS c.699C>T (tHcy, betaine, cystathionine) and TCN2 c.776C>G (MMA). No associations were observed for the other polymorphisms investigated...
  13. ncbi Changes in basal and postmethionine load concentrations of total homocysteine and cystathionine after B vitamin intervention
    Øyvind Bleie
    Institute of Medicine, University of Bergen, Haukeland University Hospital, N 5021 Bergen, Norway
    Am J Clin Nutr 80:641-8. 2004
    ....
  14. ncbi Functional inference of the methylenetetrahydrofolate reductase 677C > T and 1298A > C polymorphisms from a large-scale epidemiological study
    Arve Ulvik
    LOCUS for Homocysteine and Related Vitamins, Department of Internal Medicine, Pharmacology Section, University of Bergen, Armauer Hansens Hus, 5021 Bergen, Norway
    Hum Genet 121:57-64. 2007
    ..In conclusion, this report demonstrates functional inference of the MTHFR 677 C > T and 1,298 A > C polymorphisms from a large-scale epidemiological study...
  15. ncbi Folate, vitamin B12, homocysteine, and the MTHFR 677C->T polymorphism in anxiety and depression: the Hordaland Homocysteine Study
    Ingvar Bjelland
    Department of Public Health and Primary Health Care, LOCUS for Homocysteine and Related Vitamins, University of Bergen, Norway
    Arch Gen Psychiatry 60:618-26. 2003
    ..This study examined the associations between folate, total homocysteine, vitamin B12, and the methylenetetrahydrofolate reductase 677C-->T polymorphism, and anxiety and depression in a large population-based study...
  16. ncbi Coffee consumption and circulating B-vitamins in healthy middle-aged men and women
    Arve Ulvik
    LOCUS for Homocysteine and Related Vitamins, Department of Internal Medicine, Pharmacology Section, University of Bergen, Bergen, Norway
    Clin Chem 54:1489-96. 2008
    ..tHcy is determined by several B-vitamins. However, reports about the association between coffee intake and B-vitamin status are few...
  17. ncbi Risk of diabetes after gestational diabetes and preeclampsia. A registry-based study of 230,000 women in Norway
    Anders Engeland
    Department of Pharmacoepidemiology, Division of Epidemiology, Norwegian Institute of Public Health, Nydalen, Oslo, Norway
    Eur J Epidemiol 26:157-63. 2011
    ..If the increase in frequency of GDM observed in MBRN in recent years is real, a further increase in diabetic women can be expected...
  18. ncbi Plasma homocysteine, folate, and vitamin B 12 and the risk of hip fracture: the hordaland homocysteine study
    Clara Gram Gjesdal
    Department of Public Helath and Primary Health Care, University of Bergen, Bergen, Norway
    J Bone Miner Res 22:747-56. 2007
    ..High levels of homocysteine and low levels of folate predicted fracture, whereas vitamin B12 and genotypes were not related to fracture risk. High homocysteine may be a modifiable risk factor for hip fracture...
  19. ncbi Phenotypic expression of the methylenetetrahydrofolate reductase 677C-->T polymorphism and flavin cofactor availability in thyroid dysfunction
    Steinar Hustad
    LOCUS for Homocysteine and Related Vitamins, University of Bergen, Bergen, Norway
    Am J Clin Nutr 80:1050-7. 2004
    ..Riboflavin status modifies the metabolic effect of the polymorphism, and thyroid hormones increase the synthesis of flavin cofactors...
  20. ncbi Divergent associations of plasma choline and betaine with components of metabolic syndrome in middle age and elderly men and women
    Svetlana V Konstantinova
    Department of Public Health and Primary Health Care, University of Bergen, Bergen 5020, Norway
    J Nutr 138:914-20. 2008
    ..Choline and betaine were associated in opposite directions with key components of metabolic syndrome, suggesting a disruption of mitochondrial choline dehydrogenase pathway...
  21. ncbi Hematological parameters and cobalamin status in infants born to smoking mothers
    Anne Lise Bjørke Monsen
    Department of Pediatrics, University of Bergen, Bergen, Norway
    Biol Neonate 85:249-55. 2004
    ..At 6 weeks, maternal smoking significantly predicted the methylmalonic acid and total homocysteine levels, suggesting an influence from smoking on the cobalamin function in these infants...
  22. ncbi Infant birth size is not associated with maternal intake and status of folate during the second trimester in Norwegian pregnant women
    Roy M Nilsen
    Department of Public Health and Primary Health Care, University of Bergen, Bergen 5020, Norway
    J Nutr 140:572-9. 2010
    ..3; 95% CI: 1.6, 3.3). This study of well-nourished Norwegian pregnant women suggests that dietary folate and plasma folate during the second trimester are not risk factors for infant birth size...
  23. ncbi Early postoperative mortality after 67,548 total hip replacements: causes of death and thromboprophylaxis in 68 hospitals in Norway from 1987 to 1999
    Stein Atle Lie
    Section for Medical Statistics, Armauer Hansens Hus, University of Bergen, Haukeland Hospital, Norway
    Acta Orthop Scand 73:392-9. 2002
    ..We found only a slight reduction in the 60-day postoperative mortality during the period 1987-1999. All underlying diagnoses for a prosthesis operation had a higher 60-day postoperative mortality than primary osteoarthrosis...
  24. ncbi Failure of total knee arthroplasty with or without patella resurfacing
    Stein Håkon Låstad Lygre
    The Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway
    Acta Orthop 82:282-92. 2011
    ..We assessed the impact on prosthesis survival of patella resurfacing and of prosthesis brand, based on data from the Norwegian Arthroplasty Register...
  25. ncbi Maternal tryptophan and kynurenine pathway metabolites and risk of preeclampsia
    Roy M Nilsen
    Department of Heart Disease, Haukeland University Hospital, Bevital AS, Norway
    Obstet Gynecol 119:1243-50. 2012
    ..To estimate the association of maternal plasma concentrations of tryptophan and six kynurenine pathway metabolites with the risk of preeclampsia...
  26. ncbi Self-selection and bias in a large prospective pregnancy cohort in Norway
    Roy M Nilsen
    Department of Public Health and Primary Health Care, University of Bergen, Kalfarveien 31, N 5018 Bergen, Norway
    Paediatr Perinat Epidemiol 23:597-608. 2009
    ....
  27. ncbi Colorectal cancer and the methylenetetrahydrofolate reductase 677C -> T and methionine synthase 2756A -> G polymorphisms: a study of 2,168 case-control pairs from the JANUS cohort
    Arve Ulvik
    Department of Pharmacology, University of Bergen, Armauer Hansens Hus, N 5021 Bergen, Bergen, Norway
    Cancer Epidemiol Biomarkers Prev 13:2175-80. 2004
    ..In summary, we found significantly reduced risk of colorectal cancer in subjects with the MTHFR 677 TT and MTR 2756 GG genotypes. No interaction between the polymorphisms, or of either polymorphism with tHcy, was detected...
  28. ncbi Antibiotic prophylaxis in total hip arthroplasty: effects of antibiotic prophylaxis systemically and in bone cement on the revision rate of 22,170 primary hip replacements followed 0-14 years in the Norwegian Arthroplasty Register
    Lars B Engesaeter
    The Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway
    Acta Orthop Scand 74:644-51. 2003
    ..This observational study shows that the best results were recorded when antibiotic prophylaxis was given both systemically and in the bone cement, and if the systemic antibiotic was given 4 times on the day of surgery...
  29. ncbi Smoking and deaths between 40 and 70 years of age in women and men
    Stein Emil Vollset
    Section for Epidemiology and Medical Statistics, Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway
    Ann Intern Med 144:381-9. 2006
    ..Despite similar rates for lung cancer death, women who smoked had lower mortality rates in middle age than men with similar smoking histories due to fewer cardiovascular deaths in women...
  30. ncbi Betaine and folate status as cooperative determinants of plasma homocysteine in humans
    Pal I Holm
    LOCUS for Homocysteine and Related Vitamins, University of Bergen, Norway
    Arterioscler Thromb Vasc Biol 25:379-85. 2005
    ..Two published studies have demonstrated that betaine in the circulation is a determinant of plasma total homocysteine, but none had sufficient power to investigate the possible effect modification by folate status...
  31. ncbi Self-reported smoking status and plasma cotinine concentrations among pregnant women in the Norwegian Mother and Child Cohort Study
    Liv G Kvalvik
    Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway
    Pediatr Res 72:101-7. 2012
    ..In this prospective study, we validated self-reported tobacco use against nicotine exposure assessed by plasma cotinine in the Norwegian Mother and Child Cohort Study (MoBa)...
  32. ncbi Sickness absence with musculoskeletal or mental diagnoses, transition into disability pension and all-cause mortality: a 9-year prospective cohort study
    Sturla Gjesdal
    Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway
    Scand J Public Health 37:387-94. 2009
    ..A special focus was on possible differences in mortality among women and men who obtained disability pension (DP) as compared to those who did not...
  33. ncbi Cohort profile: cohort of Norway (CONOR)
    Oyvind Naess
    Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway
    Int J Epidemiol 37:481-5. 2008
  34. ncbi Risk of fetal death after pandemic influenza virus infection or vaccination
    Siri E Håberg
    Norwegian Institute of Public Health, Oslo, Norway
    N Engl J Med 368:333-40. 2013
    ..This concern was complicated by questions about vaccine safety in pregnant women that were raised by anecdotal reports of fetal deaths after vaccination...
  35. ncbi Cerebral palsy among term and postterm births
    Dag Moster
    Department of Public Health and Primary Health Care, University of Bergen, PO Box 7804, N 5020 Bergen, Norway
    JAMA 304:976-82. 2010
    ..There is little information on the relation of CP risk to gestational age in the term range, where most CP occurs...
  36. ncbi Changes in knowledge and attitudes of folate, and use of dietary supplements among women of reproductive age in Norway 1998-2000
    Anne Kjersti Daltveit
    Department of Public Health and Primary Health Care, University of Bergen, Norway
    Scand J Public Health 32:264-71. 2004
    ..The authors wished to establish Norwegian data on knowledge of, use of, and attitudes to folic acid supplement and dietary supplements before and after implementing national information campaigns on folate and pregnancy...
  37. ncbi Validation of disease registration in pregnant women in the Medical Birth Registry of Norway
    Anders Engeland
    Department of Pharmacoepidemiology, Division of Epidemiology, Norwegian Institute of Public Health, N 0403, Oslo, Norway
    Acta Obstet Gynecol Scand 88:1083-9. 2009
    ..The registration of asthma overall was 51%, but considerably higher for more serious asthma. Except for diabetes type 1, the medical disease diagnoses in the MBRN should be dealt with carefully...
  38. ncbi Associations between cod liver oil use and symptoms of depression: the Hordaland Health Study
    Maria Baroy Raeder
    Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Helse Bergen HF, N 5021 Bergen, Norway
    J Affect Disord 101:245-9. 2007
    ..This study aimed to evaluate the association between intake of cod liver oil, rich in omega-3 fatty acids, and high levels of symptoms of depression and anxiety in the general population...
  39. ncbi Relative importance of risk factors for coronary heart disease--the Hordaland Homocysteine study
    Jannicke Igland
    Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway
    Scand Cardiovasc J 46:316-23. 2012
    ..The aim was to rank coronary heart disease (CHD) risk factors according to their importance in predicting CHD morbidity and mortality using a scale-independent statistical approach...
  40. ncbi Usefulness and safety of percutaneous myocardial laser revascularization for refractory angina pectoris
    Mohammed Salem
    Department of Heart Disease, Haukeland University Hospital, Bergen, Norway
    Am J Cardiol 93:1086-91. 2004
    ..We conclude that PMLR therapy is reasonably safe and effective as symptomatic improvement in patients refractory to medical therapy, and that the clinical benefit is not attributable to placebo effect or investigator bias...
  41. ncbi Plasma total homocysteine and hospitalizations for cardiovascular disease: the Hordaland Homocysteine Study
    Eha Nurk
    Department of Public Health and Primary Health Care, University of Bergen, Armauer Hansen s Building, N 5021 Bergen, Norway
    Arch Intern Med 162:1374-81. 2002
    ..Elevated total plasma homocysteine (tHcy) level is a risk factor for occlusive disease in the coronary, cerebral, and peripheral vessels and is related to several lifestyle factors associated with cardiovascular disease (CVD)...
  42. ncbi Secular trends in the epidemiology of pre-eclampsia throughout 40 years in Norway: prevalence, risk factors and perinatal survival
    Kari Klungsøyr
    Department of Public Health and Primary Health Care, University of Bergen, Kalfarveien 31, Bergen, Norway
    Paediatr Perinat Epidemiol 26:190-8. 2012
    ..Finally, stillbirth associated with pre-eclampsia decreased more than neonatal mortality over time, and in the last 5 years only a moderate excess risk of stillbirth and neonatal death was observed...
  43. ncbi Early failures among 7,174 primary total knee replacements: a follow-up study from the Norwegian Arthroplasty Register 1994-2000
    Ove Furnes
    Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway
    Acta Orthop Scand 73:117-29. 2002
    ..In tricompartmental knees, however, there were more revisions because of an infection. The relatively few patients with uncemented and hybrid implants showed no improvements in results compared to cemented knee prostheses...
  44. ncbi International retrospective cohort study of neural tube defects in relation to folic acid recommendations: are the recommendations working?
    Lorenzo D Botto
    National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    BMJ 330:571. 2005
    ..To evaluate the effectiveness of policies and recommendations on folic acid aimed at reducing the occurrence of neural tube defects...
  45. ncbi Plasma concentration of folate as a biomarker for the intake of fruit and vegetables: the Hordaland Homocysteine Study
    Asgeir Brevik
    Department of Nutrition, School of Medicine, University of Oslo, Oslo, Norway
    Am J Clin Nutr 81:434-9. 2005
    ..Nutritional biomarkers may be used to assess dietary exposure without the errors commonly associated with self-reported dietary data...
  46. ncbi Two distinct aetiologies of cardia cancer; evidence from premorbid serological markers of gastric atrophy and Helicobacter pylori status
    Svein Hansen
    The Cancer Registry of Norway, Institute of Population Based Cancer Research, Oslo, Norway
    Gut 56:918-25. 2007
    ..Non-cardia gastric adenocarcinoma is positively associated with Helicobacter pylori infection and atrophic gastritis. The role of H pylori infection and atrophic gastritis in cardia cancer is unclear...
  47. ncbi Homocysteine and folate in pregnancy
    Per Magne Ueland
    Clin Chem 50:1293-5. 2004
  48. ncbi Thermolabile methylenetetrahydrofolate reductase, homocysteine, and cardiovascular disease risk: the European Concerted Action Project
    Raymond Meleady
    Department of Cardiology, Adelaide Meath Hospital, Incorporating the National Children s Hospital, Tallaght, Dublin, Ireland
    Am J Clin Nutr 77:63-70. 2003
    ..5.1.20) enzyme have elevated plasma concentrations of the cardiovascular disease risk factor homocysteine, particularly if folate depleted...
  49. ncbi Folate and one-carbon metabolism gene polymorphisms and their associations with oral facial clefts
    Abee L Boyles
    Epidemiology Branch, National Institute of Environmental Health Sciences NIH, Durham, North Carolina 27709, USA
    Am J Med Genet A 146:440-9. 2008
    ..No associations were found between any of the polymorphisms and CPO. Genetic variations in the nine metabolic genes examined here do not confer a substantial degree of risk for clefts...
  50. ncbi Low fasting methionine concentration as a novel risk factor for recurrent venous thrombosis
    Miranda B A J Keijzer
    Department of Endocrinology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Thromb Haemost 96:492-7. 2006
    ..This risk association was stronger for methionine than for homocysteine or cysteine. This supports the hypothesis that impaired methylation may be involved in the pathogenesis of venous thrombosis...
  51. ncbi Folic acid supplements and risk of facial clefts: national population based case-control study
    Allen J Wilcox
    Epidemiology Branch, National Institute of Environmental Health Sciences NIH, Durham, NC 27709, USA
    BMJ 334:464. 2007
    ..To explore the role of folic acid supplements, dietary folates, and multivitamins in the prevention of facial clefts...
  52. ncbi Circulating concentrations of folate and vitamin B12 in relation to prostate cancer risk: results from the European Prospective Investigation into Cancer and Nutrition study
    Mattias Johansson
    Department of Surgical and Perioperative Sciences, Urology and Andrology, Umea University, 901 85 Umea, Sweden
    Cancer Epidemiol Biomarkers Prev 17:279-85. 2008
    ..The aim of the present study was to investigate the relationship between prostate cancer risk and circulating concentrations of folate and vitamin B(12) in a large prospective cohort...
  53. ncbi Mortality and cardiovascular events in patients treated with homocysteine-lowering B vitamins after coronary angiography: a randomized controlled trial
    Marta Ebbing
    Department of Heart Disease, Haukeland University Hospital, Jonas Liesvei 65, 5021 Bergen, Norway
    JAMA 300:795-804. 2008
    ..Observational studies have reported associations between circulating total homocysteine concentration and risk of cardiovascular disease. Oral administration of folic acid and vitamin B(12) can lower plasma total homocysteine levels...
  54. ncbi Dietary fat and plasma total homocysteine concentrations in 2 adult age groups: the Hordaland Homocysteine Study
    Paula Berstad
    Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Norway
    Am J Clin Nutr 85:1598-605. 2007
    ..The intake of n-3 (formerly called omega-3) fatty acids (FAs) may be inversely associated with plasma total homocysteine (tHcy) concentrations, but the epidemiologic data are sparse...
  55. ncbi [Does folic acid have effects on other health problems than neural tube defects?]
    Anne Cathrine Staff
    Kvinnesenteret, Kvinne barn divisjonen, Ulleval universitetssykehus, 0450 Oslo
    Tidsskr Nor Laegeforen 125:438-41. 2005
    ..Evidence concerning effect of increased intake on cardiovascular disease, cancer and other diseases has recently been evaluated in a report to the Directorate of Health and Social Welfare in Norway...
  56. ncbi Holo-transcobalamin is an early marker of changes in cobalamin homeostasis. A randomized placebo-controlled study
    Ebba Nexo
    Department of Clinical Biochemistry, AKH, Aarhus University Hospital, DK 8000 Aarhus C, Denmark
    Clin Chem 48:1768-71. 2002
    ..We examined the effect of oral vitamin B(12) treatment on fluctuations in plasma total cobalamin and its binding proteins transcobalamin (TC) and haptocorrin (HC)...
  57. ncbi [Hospital admission rates for cardiovascular diseases in Western Norway, 1992-2001]
    Nina Øyen
    Institutt for samfunnsmedisinske fag, Universitetet i Bergen, Postboks 7804 5020 Bergen
    Tidsskr Nor Laegeforen 128:17-23. 2008
    ..Hospital admission rates, and case-fatality were compared with regional mortality rates for cardiovascular diseases...
  58. ncbi Folate and depression
    Ingvar Bjelland
    Psychother Psychosom 72:59-60. 2003
  59. ncbi Neonatal hip instability and risk of total hip replacement in young adulthood: follow-up of 2,218,596 newborns from the Medical Birth Registry of Norway in the Norwegian Arthroplasty Register
    Ingvild Ø Engesaeter
    The Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, UNIFOB, Bergen
    Acta Orthop 79:321-6. 2008
    ..Dysplasia is probably the most common underlying condition in osteoarthritis of the hip, leading to total hip replacement (THR) in young adulthood. We investigated whether hip instability at birth predisposes to THR in young adulthood...
  60. ncbi [The Norwegian registry of joint prostheses--15 beneficial years for both the patients and the health care]
    Ove Furnes
    Nasjonalt register for leddproteser Ortopedisk klinikk Haukeland Universitetssykehus 5021 Bergen
    Tidsskr Nor Laegeforen 123:1367-9. 2003
  61. ncbi [Risk of disability pension among young persons on long-term sick leave]
    Sturla Gjesdal
    Program for helseøkonomi og Seksjon for sosialmedisin
    Tidsskr Nor Laegeforen 125:1801-5. 2005
    ..In the late 1990s the incidence of new disability pensioners in Norway increased, especially among young people. This study assessed the risk and possible predictors of a transition to disability among long-term sickness absentees below 40...
  62. ncbi [Effects of public initiatives aimed at reducing neural tube defects with folic acid supplementation]
    Anne Cathrine Staff
    Kvinnesenteret, Kvinne barn divisjonen, Ulleval universitetssykehus, HF 0450 Oslo
    Tidsskr Nor Laegeforen 125:435-7. 2005
    ..Compliance with and effects of this recommendation has recently been evaluated in Norway in a report to the Directorate of Health and Social Welfare...