Research Topics
Species | S E VollsetSummaryAffiliation: University of Bergen Country: Norway Publications
| Collaborators
|
Detail Information
Publications
Plasma total homocysteine and cardiovascular and noncardiovascular mortality: the Hordaland Homocysteine StudyS E Vollset
LOCUS for Homocysteine and Related Vitamins, University of Bergen, Bergen, Norway
Am J Clin Nutr 74:130-6. 2001..Few population-based studies have assessed relations between plasma or serum total homocysteine (tHcy) and all-cause mortality...
Plasma total homocysteine, pregnancy complications, and adverse pregnancy outcomes: the Hordaland Homocysteine studyS E Vollset
Section for Medical Statistics, The Department of Public Health and Primary Health Care, Norway
Am J Clin Nutr 71:962-8. 2000..Total homocysteine (tHcy) measured in serum or plasma is a marker of folate status and a risk factor for cardiovascular disease...
Lifestyle and cardiovascular disease risk factors as determinants of total cysteine in plasma: the Hordaland Homocysteine StudyL El-Khairy
Department of Public Health and Primary Health Care and the Department of Pharmacology, University of Bergen, Norway
Am J Clin Nutr 70:1016-24. 1999..Cysteine is structurally and metabolically related to homocysteine, but data on its association with cardiovascular disease and cardiovascular disease risk factors are sparse...
Major lifestyle determinants of plasma total homocysteine distribution: the Hordaland Homocysteine StudyO Nygard
Department of Public Health and Primary Health Care, University of Bergen, Norway
Am J Clin Nutr 67:263-70. 1998..These findings are relevant for establishing adequate reference ranges for tHcy and emphasize folate intake, smoking status, and coffee consumption as major acquired determinants of tHcy concentration in this general population...
Factor V Leiden, pregnancy complications and adverse outcomes: the Hordaland Homocysteine StudyE Nurk
Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway
QJM 99:289-98. 2006..The factor V Leiden (FVL) mutation is the most common cause of inherited thrombophilia in Caucasian populations, and women with this variant allele are at increased risk for pregnancy complications...
Coffee consumption and plasma total homocysteine: The Hordaland Homocysteine StudyO Nygard
Department of Clinical Biology, University of Bergen, Norway
Am J Clin Nutr 65:136-43. 1997..The results of the present report should promote future studies on tHcy as a possible mediator of adverse clinical effects related to heavy coffee consumption...
Hyperhomocysteinemia and elevated methylmalonic acid indicate a high prevalence of cobalamin deficiency in Asian IndiansH Refsum
Department of Pharmacology and the Locus for Homocysteine and Related Vitamins, University of Bergen, Norway
Am J Clin Nutr 74:233-41. 2001..In India, most people adhere to a vegetarian diet, which may lead to cobalamin deficiency...
The Hordaland Homocysteine StudiesP M Ueland
LOCUS for Homocysteine and Related Vitamins, Armauer Hansens Hus, University of Bergen, Norway
Lipids 36:S33-9. 2001..The Hordaland Homocysteine cohort will be used for future investigations of the stability of tHcy and vitamin status over time, and to investigate associations with mortality and morbidity including cancer incidence...
Homocysteine and cardiovascular diseaseH Refsum
Department of Pharmacology, University of Bergen, Norway
Annu Rev Med 49:31-62. 1998..Supplementation with B-vitamins, in particular with folic acid, is an efficient, safe, and inexpensive means to reduce an elevated tHcy level. Studies are now in progress to establish whether such therapy will reduce cardiovascular risk...
Riboflavin as a determinant of plasma total homocysteine: effect modification by the methylenetetrahydrofolate reductase C677T polymorphismS Hustad
LOCUS for Homocysteine and Related Vitamins, University of Bergen, Armauer Hansens Hus, N 5021 Bergen, Norway
Clin Chem 46:1065-71. 2000..This motivates the investigation of the possible relationship between riboflavin status and tHcy...
Combined analyses and extended follow-up of two randomized controlled homocysteine-lowering B-vitamin trialsM Ebbing
Department of Heart Disease, Haukeland University Hospital, Bergen, Norway
J Intern Med 268:367-82. 2010....
Biological and clinical implications of the MTHFR C677T polymorphismP M Ueland
LOCUS for Homocysteine and Related Vitamins, Armauer Hanssens hus, University of Bergen, 5021, Bergen, Norway
Trends Pharmacol Sci 22:195-201. 2001....
The controversy over homocysteine and cardiovascular riskP M Ueland
LOCUS for Homocysteine and Related Vitamins, Armauer Hansens Hus, University of Bergen, Norway
Am J Clin Nutr 72:324-32. 2000..Thus, only placebo-controlled intervention studies with tHcy-lowering B vitamins and clinical endpoints can provide additional valid arguments for the debate over whether tHcy is a causal CVD risk factor...
Mortality after total hip replacement: 0-10-year follow-up of 39,543 patients in the Norwegian Arthroplasty RegisterS A Lie
Division for Medical Statistics, Armauer Hansens Hus, University of Bergen, Haukeland Sykehus, Norway
Acta Orthop Scand 71:19-27. 2000..65). During the first 60 postoperative days, all patient categories had a higher mortality than the general population (0.8% mortality, SMR = 1.39)...
Homocysteine-lowering therapy does not affect inflammatory markers of atherosclerosis in patients with stable coronary artery diseaseØ Bleie
Department of Heart Disease, Haukeland University Hospital, Bergen, Norway
J Intern Med 262:244-53. 2007..We wanted to test the effect of homocysteine-lowering B-vitamin therapy, as used in the Western Norway B-vitamin Intervention Trial (WENBIT), on inflammatory markers associated with atherosclerosis...
Plasma total cysteine as a risk factor for vascular disease: The European Concerted Action ProjectL El-Khairy
LOCUS for Homocysteine and Related Vitamins, University of Bergen, Bergen, Norway
Circulation 103:2544-9. 2001..We studied the relation between plasma total cysteine (tCys) levels and the risk of vascular disease in the coronary, cerebral, and peripheral vessels...
Methylmalonic acid and homocysteine in plasma as indicators of functional cobalamin deficiency in infants on macrobiotic dietsJ Schneede
Department of Pharmacology and Toxicology, University of Bergen, Haukeland Hospital, Norway
Pediatr Res 36:194-201. 1994..Furthermore, the finding of high methylmalonic acid and total homocysteine in plasma of most macrobiotic infants demonstrates a functional cobalamin deficiency in these subjects...
Plasma total homocysteine is influenced by prandial status in humans: the Hordaland Hhomocysteine SstudyE Nurk
Department of Public Health and Primary Health Care, University of Bergen, N 5021 Bergen, Norway
J Nutr 131:1214-6. 2001....
Total homocysteine and cardiovascular diseaseO Nygard
Division for Medical Statistics, Department of Public Health, University of Bergen, Norway, Sweden
J Intern Med 246:425-54. 1999..This paper reviews the biochemical, clinical, epidemiological and experimental data underlying this conclusion and is critically questioning whether elevated tHcy is a causal factor...
Determinants of cobalamin status in newbornsA L Bjørke Monsen
LOCUS for Homocysteine and Related Vitamins, University of Bergen, Bergen, Norway
Pediatrics 108:624-30. 2001..We investigated the relation between cobalamin status in newborns and in their healthy mothers who consumed an omnivorous diet...
Distribution and determinants of serum creatinine in the general population: the Hordaland Health StudyB E Vikse
Renal Research Group, Institute of Medicine, University of Bergen, Norway
Scand J Clin Lab Invest 64:709-22. 2004..The purpose of the present study was to investigate determinants of serum creatinine in the general population...
Homocysteine and its relation to B-vitamins in Graves' disease before and after treatment: effect modification by smokingB G Nedrebø
LOCUS for Homocysteine and Related Vitamins, University of Bergen, Haukeland University Hospital, Bergen, Norway
J Intern Med 254:504-12. 2003..To investigate plasma total homocysteine levels and its relation to B-vitamins and smoking in Graves' disease before and after antithyroid therapy...
Hip disease and the prognosis of total hip replacements. A review of 53,698 primary total hip replacements reported to the Norwegian Arthroplasty Register 1987-99O Furnes
Haukeland University Hospital, Bergen, Norway
J Bone Joint Surg Br 83:579-86. 2001..If a cemented Charnley prosthesis is used, the type of disease leading to THR seems in most cases to have only a minor influence on the survival of the prosthesis...
Failure rates for 4762 revision total hip arthroplasties in the Norwegian Arthroplasty RegisterS A Lie
Section for Medical Statistics, Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway
J Bone Joint Surg Br 86:504-9. 2004..Recementation without allograft, and uncemented revision with bone impaction, were associated with worse results than the other revision techniques which we studied...
Evaluation of diagnostic tests for antinuclear antibodies in rheumatological practiceE Ulvestad
Department of Microbiology and Immunology, The Gade Institute, Haukeland University Hospital, Bergen, Norway
Scand J Immunol 52:309-15. 2000..At the given cut-off values indirect immunofluorescence on HEp-2 cells performed best. All assays except mouse kidney showed performance characteristics sufficient for use in routine analysis of ANA...
Cerebrospinal fluid proteins as indicators of nerve root compression in patients with sciatica caused by disc herniationJ S Skouen
Department of Neurology, Haukeland University Hospital, Bergen, Norway
Spine (Phila Pa 1976) 18:72-9. 1993..The cerebrospinal fluid proteins may be used as diagnostic parameters of nerve root compression, especially when surgery is a consideration or in patients in whom sciatica is unlikely...
Smoking, folate and methylenetetrahydrofolate reductase status as interactive determinants of adenomatous and hyperplastic polyps of colorectumA Ulvik
LOCUS for Homocysteine and Related Vitamins, Armauer Hansens Hus, University of Bergen, Bergen, Norway
Am J Med Genet 101:246-54. 2001..In conclusion, in smokers, high folate status may confer increased or decreased risk for HRAs, depending on the MTHFR genotype. These data demonstrate the strong gene-nutrition interaction involving the C677T MTHFR polymorphism...
