Research Topics
Genomes and GenesSpecies | Giske UrsinSummaryAffiliation: University of Oslo Country: Norway Publications
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Publications
Mammographic density and breast cancer in three ethnic groupsGiske Ursin
Department of Preventive Medicine, University of California Keck School of Medicine, Los Angeles, California 90089, USA
Cancer Epidemiol Biomarkers Prev 12:332-8. 2003..Furthermore, our findings suggest that mammographic density is as strong a predictor of risk for African-American and Asian-American women as for white women...
[Mammographic density as indicator of breast cancer risk]Giske Ursin
Institutt for ernaeringsforskning, Universitetet i Oslo, Postboks 1046 Blindern, 0316 Oslo
Tidsskr Nor Laegeforen 123:3373-6. 2003..Mammographic density has been suggested as a biomarker for breast cancer risk and is currently being used as a surrogate endpoint for breast cancer in several cancer prevention trials...
Effect of reproductive factors and oral contraceptives on breast cancer risk in BRCA1/2 mutation carriers and noncarriers: results from a population-based studyEunjung Lee
Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Room 4407, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
Cancer Epidemiol Biomarkers Prev 17:3170-8. 2008..However, the effects of these factors in BRCA1 and BRCA2 mutation carriers are less clear...
Variations in sex hormone metabolism genes, postmenopausal hormone therapy and risk of endometrial cancerPedram Razavi
Department of Preventive Medicine, University of Southern California, Los Angeles, CA, USA
Int J Cancer 130:1629-38. 2012..Variations in CYP11A1 may modify the effect of ET use on risk of postmenopausal endometrial cancer; however, larger studies are needed to explore these findings further...
Progestogen levels, progesterone receptor gene polymorphisms, and mammographic density changes: results from the Postmenopausal Estrogen/Progestin Interventions Mammographic Density StudyEunjung Lee
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
Menopause 19:302-10. 2012..Here, after adjusting for serum estrone and estrone sulfate levels, we investigated the roles of posttreatment serum progestogen increase and of progesterone receptor gene (PGR) genetic variations on changes in mammographic density...
Genetic variation in the progesterone receptor gene and risk of endometrial cancer: a haplotype-based approachEunjung Lee
Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90089, USA
Carcinogenesis 31:1392-9. 2010..We investigated whether genetic variation in PGR is also associated with endometrial cancer risk using a haplotype-based approach...
Genetic variation in peroxisome proliferator-activated receptor gamma, soy, and mammographic density in Singapore Chinese womenEunjung Lee
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Ave, Norris Cancer Center, Los Angeles, CA 90089, USA
Cancer Epidemiol Biomarkers Prev 21:635-44. 2012..We investigated the interrelations of soy, PPARγ, and mammographic density, a biomarker of breast cancer risk in a cross-sectional study of 2,038 women who were members of the population-based Singapore Chinese Health Study Cohort...
The association of polymorphisms in hormone metabolism pathway genes, menopausal hormone therapy, and breast cancer risk: a nested case-control study in the California Teachers Study cohortEunjung Lee
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
Breast Cancer Res 13:R37. 2011..It therefore seems plausible that variation in genes involved in metabolism of these hormones may affect breast cancer risk, and that these associations may vary depending on menopausal status and use of hormone therapy...
Post-treatment change in serum estrone predicts mammographic percent density changes in women who received combination estrogen and progestin in the Postmenopausal Estrogen/Progestin Interventions (PEPI) TrialGiske Ursin
Department of Preventive Medicine, Norris Comprehensive Cancer Center, Room 4407, USC Keck School of Medicine, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
J Clin Oncol 22:2842-8. 2004..We determined whether increases in serum estrone as a function of treatment predict increases in mammographic percent density...
Mitochondrial DNA G10398A variant is not associated with breast cancer in African-American womenVeronica Wendy Setiawan
Department of Preventive Medicine, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA
Cancer Genet Cytogenet 181:16-9. 2008..18, 95% CI = 0.76-1.82, P = 0.46). Our results do not support the hypothesis that the mtDNA G10398A polymorphism is, as has previously been reported, a marker of breast cancer risk in African Americans...
The relative importance of genetics and environment on mammographic densityGiske Ursin
Department of Preventive Medicine, University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, California, USA
Cancer Epidemiol Biomarkers Prev 18:102-12. 2009..We investigated whether part of the presumed heritability might be attributed to differential sharing of modifiable risk factors in monozygotic (MZ) and dizygotic (DZ) twins...
Polymorphisms in genes involved in estrogen and progesterone metabolism and mammographic density changes in women randomized to postmenopausal hormone therapy: results from a pilot studySarah J Lord
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
Breast Cancer Res 7:R336-44. 2005..Identifying genetic variants that determine increases in mammographic density in hormone users may be important in understanding hormonal carcinogenesis of the breast...
The association of endogenous sex steroids and sex steroid binding proteins with mammographic density: results from the Postmenopausal Estrogen/Progestin Interventions Mammographic Density StudyGail A Greendale
Division of Geriatrics, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA 90095 1687, USA
Am J Epidemiol 162:826-34. 2005..These results suggest that some sex steroids may increase the risk of breast cancer by stimulating breast epithelial or stromal proliferation, which appears on a mammogram as higher density...
Lifetime recreational exercise activity and breast cancer risk among black women and white womenLeslie Bernstein
Department of Preventive Medicine, Keck School of Medicine, USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA
J Natl Cancer Inst 97:1671-9. 2005....
Germ line variation at 8q24 and endometrial cancer riskVeronica Wendy Setiawan
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Harlyne Norris Research Tower, 1450 Biggy Street, Room 1504A, Los Angeles, CA 90033, USA
Cancer Epidemiol Biomarkers Prev 16:2166-8. 2007
Reproductive factors and breast cancer risk according to joint estrogen and progesterone receptor status: a meta-analysis of epidemiological studiesHuiyan Ma
Department of Preventive Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue 4407, Los Angeles, CA 90089, USA
Breast Cancer Res 8:R43. 2006..This report presents the first meta-analysis of results from epidemiological studies that have investigated parity, age at first birth, breastfeeding, and age at menarche in relation to ER+PR+ and ER-PR- cancer risk...
Age-specific effects of hormone therapy use on overall mortality and ischemic heart disease mortality among women in the California Teachers StudyDaniel O Stram
Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90033, USA
Menopause 18:253-61. 2011..The California Teachers Study questionnaire and mortality data were used to examine whether age modified the association between HT and the relative risk of overall mortality and ischemic heart disease deaths...
Long-term postmenopausal hormone therapy and endometrial cancerPedram Razavi
University of Southern California, Department of Preventive Medicine, Norris Comprehensive Cancer Center, Los Angeles, California, USA
Cancer Epidemiol Biomarkers Prev 19:475-83. 2010..These findings confirm that long-term use of ET, sequential EPT, or, among normal weight women, continuous-combined EPT is associated with increased risk of endometrial cancer...
Green tea, soy, and mammographic density in Singapore Chinese womenAnna H Wu
Department of Preventive Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
Cancer Epidemiol Biomarkers Prev 17:3358-65. 2008..52). Our findings suggest that both regular green tea and high soy intake may have beneficial effects on the breast; the effect of green tea on PMD may be stronger than the effect of soy...
Two estrogen-related variants in CYP19A1 and endometrial cancer risk: a pooled analysis in the Epidemiology of Endometrial Cancer ConsortiumVeronica Wendy Setiawan
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Cancer Epidemiol Biomarkers Prev 18:242-7. 2009..Our study provides evidence that CYP19A1 genetic variation influences susceptibility to endometrial cancer, particularly among older and obese women...
Associations between soy, diet, reproductive factors, and mammographic density in Singapore Chinese womenGiske Ursin
University of Southern California, Los Angeles, CA 90089, USA
Nutr Cancer 56:128-35. 2006..Our results suggest that the effect of soy intake on percent mammographic density is moderate but possibly of clinical relevance...
Serum prolactin levels are positively associated with mammographic density in postmenopausal womenGail A Greendale
Division of Geriatrics, David Geffen School of Medicine at UCLA, 10945 Le Conte Avenue, Suite 2339, Los Angeles, CA 90095 1687, USA
Breast Cancer Res Treat 105:337-46. 2007..Mammographic density is a strong, independent predictor of breast cancer and, therefore, a potential surrogate indicator of breast cancer risk...
The role of established breast cancer susceptibility loci in mammographic density in young womenEunjung Lee
Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
Cancer Epidemiol Biomarkers Prev 17:258-60. 2008
Hormone-related risk factors for breast cancer in women under age 50 years by estrogen and progesterone receptor status: results from a case-control and a case-case comparisonHuiyan Ma
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, USC Norris Comprehensive Cancer Center, Los Angeles, California 90089 9175, USA
Breast Cancer Res 8:R39. 2006..It has been suggested that hormonal risk factors act predominantly on estrogen receptor and progesterone receptor (ER/PR)-positive breast cancers. However, the data have been inconsistent, especially in younger women...
Does mammographic density reflect ethnic differences in breast cancer incidence rates?Zhengjia Chen
Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA
Am J Epidemiol 159:140-7. 2004..This study suggests that absolute but not percent mammographic density reflects the lower breast cancer incidence rates of Asian Americans in relation to those of African Americans and Whites...
Evaluation of unclassified variants in the breast cancer susceptibility genes BRCA1 and BRCA2 using five methods: results from a population-based study of young breast cancer patientsEunjung Lee
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, USC Norris Comprehensive Cancer Center, Los Angeles, CA 90089 9175, USA
Breast Cancer Res 10:R19. 2008....
Breast cancer risk and ovariectomy, hysterectomy, and tubal sterilization in the women's contraceptive and reproductive experiences studyDavid J Press
Department of Preventive Medicine, Keck School of Medicine, and Norris Comprehensive Can cer Center, University of Southern California, Los Angeles, California, USA
Am J Epidemiol 173:38-47. 2011..No association with breast cancer risk was observed with tubal sterilization only or partial ovariectomy without hysterectomy. Reproductive organ surgeries may alter ovarian hormone levels, thereby affecting breast cancer risk...
Age at last birth in relation to risk of endometrial cancer: pooled analysis in the epidemiology of endometrial cancer consortiumVeronica Wendy Setiawan
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
Am J Epidemiol 176:269-78. 2012..In this large pooled analysis, late age at last birth was independently associated with a reduced risk of endometrial cancer, and the reduced risk persisted for many years...
Reproductive factors and risk of breast carcinoma in a study of white and African-American womenGiske Ursin
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
Cancer 101:353-62. 2004....
Menopausal hormone therapy and subsequent risk of specific invasive breast cancer subtypes in the California Teachers StudyTanmai Saxena
Department of Preventive Medicine, Norris Comprehensive Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, California, USA
Cancer Epidemiol Biomarkers Prev 19:2366-78. 2010....
A variant in the cytochrome p450 oxidoreductase gene is associated with breast cancer risk in African AmericansChristopher A Haiman
Departments of Preventive Medicine and Pathology, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
Cancer Res 67:3565-8. 2007..03) and stronger in those with advanced disease (411 cases and 877 controls; OR, 2.60; 95% CI, 1.56-4.34; P = 0.0002). These data suggest that African Americans harbor an allele at the POR locus that may increase breast cancer risk...
Risk factors for surgically removed fibroids in a large cohort of teachersClaire Templeman
Department of Obstetrics and Gynecology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
Fertil Steril 92:1436-46. 2009..To describe reproductive and lifestyle correlates of surgically confirmed fibroids...
Polymorphism in the androgen receptor and mammographic density in women taking and not taking estrogen and progestin therapyElizabeth Osth Lillie
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089 9175, USA
Cancer Res 64:1237-41. 2004..4%) than carriers of the more active AR-CAG (25.7%; P = 0.04). Our results raise the question of whether the number of AR-CAG repeats predicts breast cancer risk in estrogen progestin therapy users...
Positive association between mammographic breast density and bone mineral density in the Postmenopausal Estrogen/Progestin Interventions StudyCarolyn Crandall
Division of General Internal Medicine, David Geffen School of Medicine at University of California, Los Angeles, CA, USA
Breast Cancer Res 7:R922-8. 2005..We hypothesized that demonstration of an association between mammographic breast density and bone mineral density (BMD) would suggest a unifying underlying mechanism influencing both breast density and BMD...
Characteristics of triple-negative breast cancer in patients with a BRCA1 mutation: results from a population-based study of young womenEunjung Lee
Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA
J Clin Oncol 29:4373-80. 2011..These tumors have a poor prognosis, remain a clinical challenge, and are more common among women with BRCA1 mutations. We tested whether there are distinguishing features of TNBC after BRCA1 mutation status has been taken into account...
Cigarette smoking is not associated with breast cancer risk in young womenJennifer Prescott
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA
Cancer Epidemiol Biomarkers Prev 16:620-2. 2007
Genetic determinants of mammographic densityChristopher A Haiman
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
Breast Cancer Res 4:R5. 2002..Changes in breast density are highly correlated with steroid hormone exposure...
Greatly increased occurrence of breast cancers in areas of mammographically dense tissueGiske Ursin
Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA
Breast Cancer Res 7:R605-8. 2005..We addressed this question by studying ductal carcinoma in situ (DCIS), as revealed by microcalcifications...
Association of new-onset breast discomfort with an increase in mammographic density during hormone therapyCarolyn J Crandall
Divisions of General Internal Medicine, The David Geffen School of Medicine at UCLA, University of California Los Angeles, 911 Broxton Avenue, Los Angeles, CA 90024, USA
Arch Intern Med 166:1578-84. 2006..Postmenopausal use of estrogen and progestin therapy increases breast density and breast discomfort. Whether this increase in breast density is heralded by new-onset breast discomfort is unknown...
Postmenopausal hormone therapy and change in mammographic densityGail A Greendale
Division of Geriatric Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
J Natl Cancer Inst 95:30-7. 2003..Mammographic density is an independent risk factor for breast cancer. Postmenopausal hormone use is associated with an increase in mammographic density, but the magnitude of the density increase is unknown...
Urinary 2-hydroxyestrone/16alpha-hydroxyestrone ratio and family history of breast cancer in premenopausal womenGiske Ursin
Department of Preventive Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles 90089, USA
Breast Cancer Res Treat 72:139-43. 2002..Our data suggest that among premenopausal women, family history is not associated with higher urinary estrogen levels or a lower ratio of urinary 2-OHE1/16alpha-OHE1...
The association between recreational physical activity and mammographic densityConchitina Chato Siozon
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA
Int J Cancer 119:1695-701. 2006..07) and percent (p for trend = 0.08) mammographic density after adjustment for BMI. Our results suggest that physical activity is not a strong predictor of mammographic density...
Does menopausal hormone replacement therapy interact with known factors to increase risk of breast cancer?Giske Ursin
Department of Preventive Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA 90089, USA
J Clin Oncol 20:699-706. 2002....
Associations between polymorphisms in the steroid 5-alpha reductase type II (SRD5A2) gene and benign prostatic hyperplasia and prostate cancerMuhammad T Salam
Department of Preventive Medicine, University of Southern California, Los Angeles, Los Angeles, CA 90089, USA
Urol Oncol 23:246-53. 2005..03). Prostate cancer and BPH were not associated with the alanine-49 to threonine single nucleotide polymorphism and the (TA)n repeat. These results suggest that the SRD5A2 gene may play an important role in both BPH and prostate cancer...
Adenomyosis and endometriosis in the California Teachers StudyClaire Templeman
Department of Obstetrics and Gynecology, University of Southern California Keck School of Medicine, Los Angeles, California, USA
Fertil Steril 90:415-24. 2008..To evaluate the reproductive and lifestyle correlates of a surgically confirmed diagnosis of endometriosis or adenomyosis in a large prospective cohort...
The role of androgens and polymorphisms in the androgen receptor in the epidemiology of breast cancerElizabeth O Lillie
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Breast Cancer Res 5:164-73. 2003..We review the quality of this evidence and conclude with a discussion of how the androgen receptor and testosterone results coincide...
Induced abortion, miscarriage, and breast cancer risk of young womenMaya Mahue-Giangreco
Department of Preventive Medicine and Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
Cancer Epidemiol Biomarkers Prev 12:209-14. 2003..Risk declined as the number of induced abortions increased (P = 0.04). Our results do not support the hypothesis that induced abortion or miscarriage increase the breast cancer risk of young women...
Oral contraceptives and the risk of breast cancerPolly A Marchbanks
Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, USA
N Engl J Med 346:2025-32. 2002..CONCLUSIONS: Among women from 35 to 64 years of age, current or former oral-contraceptive use was not associated with a significantly increased risk of breast cancer...
Relation of regimens of combined hormone replacement therapy to lobular, ductal, and other histologic types of breast carcinomaJanet R Daling
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
Cancer 95:2455-64. 2002..However, the use of combined (estrogen and progestin) hormone replacement therapy (CHRT) also has increased during the last decade and may account in part for the increase in invasive lobular breast carcinoma...
Racial differences in the familial aggregation of breast cancer and other female cancersMichael S Simon
Division of Haematology and Oncology, Barbara Ann Karmanos Cancer Institute, 4100 John R, 4221 Hudson, Weber Cancer Research Building, Detroit, M1 48201, USA
Breast Cancer Res Treat 89:227-35. 2005..17 (1.22-3.85). In conclusion, these racially distinct aggregation patterns may reflect different modes of inheritance and/or environmental factors that impact cancer risk...
Association of regimens of hormone replacement therapy to prognostic factors among women diagnosed with breast cancer aged 50-64 yearsJanet R Daling
Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seattle, Washington 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 12:1175-81. 2003....
The NICHD Women's Contraceptive and Reproductive Experiences Study: methods and operational resultsPolly A Marchbanks
Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Ann Epidemiol 12:213-21. 2002..5% and 78.6%, respectively, with lower rates for black women and older women. CONCLUSIONS: The methodologic details of this large collaboration may assist researchers conducting similar investigations...
Alcohol exposure and breast cancer: results of the women's contraceptive and reproductive experiences studyJill A McDonald
National Center for Chronic Disease Prevention and Health Promotion, Division of Reproductive Health, 4770 Buford Highway Northeast, MS-K22, Atlanta, GA 30341-3724, USA
Cancer Epidemiol Biomarkers Prev 13:2106-16. 2004..Further work is needed to explain how alcohol exposure, sex hormones, and tumor receptor status interact...
Does breast size modify the association between mammographic density and breast cancer risk?Anne Stuedal
Department of Nutrition, University of Oslo, Oslo, Norway
Cancer Epidemiol Biomarkers Prev 17:621-7. 2008..S. women. Because African American women have a larger breast size, we assessed whether the association between mammographic density and breast cancer was less apparent in large than in small breasts...
Vitamin D receptor polymorphisms and breast cancer risk in a large population-based case-control study of Caucasian and African-American womenBritton Trabert
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Fairview Ave N, Seattle, Washington 98109 1024, USA
Breast Cancer Res 9:R84. 2007..The involvement of vitamin D receptor (VDR), which is a key mediator in the vitamin D pathway, in breast cancer etiology has long been of interest...
Low-dose medical radiation exposure and breast cancer risk in women under age 50 years overall and by estrogen and progesterone receptor status: results from a case-control and a case-case comparisonHuiyan Ma
Institute for Health Promotion and Disease Prevention Research, Keck School of Medicine, University of Southern California, 1000 South Fremont Avenue, Unit 8, Alhambra, CA 91803, USA
Breast Cancer Res Treat 109:77-90. 2008..We found no effect modification by ER/PR status. In conclusion, our findings support the hypothesis that low-dose ionizing radiation, and particularly exposures during childhood, increase breast cancer risk...
Prevalence and predictors of BRCA1 and BRCA2 mutations in a population-based study of breast cancer in white and black American women ages 35 to 64 yearsKathleen E Malone
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Cancer Res 66:8297-308. 2006....
Endogenous sex hormones, prolactin and mammographic density in postmenopausal Norwegian womenYngve Bremnes
Institute of Community Medicine, University of Tromsø, Tromsø, Norway
Int J Cancer 121:2506-11. 2007..Further, the authors found a positive but weak association between plasma estrone concentration and mammographic density, which appeared to be modified by IGF-I levels...
Breast cancer risk estimates for relatives of white and African American women with breast cancer in the Women's Contraceptive and Reproductive Experiences StudyMichael S Simon
Division of Hematology and Oncology, Karmanos Cancer Institute at Wayne State University, Detroit, MI 48201, USA
J Clin Oncol 24:2498-504. 2006..The purpose of this report is to update breast cancer risk estimates associated with a family history of breast cancer for white and AA women...
Different types of postmenopausal hormone therapy and mammographic density in Norwegian womenYngve Bremnes
Institute of Community Medicine, University of Tromsø, Tromsø, Norway
Int J Cancer 120:880-4. 2007..In summary, our study shows a statistical significant positive dose-response association between current use of the continuous E(2) plus NETA combination and both measures of mammographic density...
Mammographic density, hormone therapy, and risk of breast cancerGiske Ursin
Cancer Epidemiol Biomarkers Prev 15:1750; author reply 1750. 2006
Plasma levels of leptin and mammographic density among postmenopausal women: a cross-sectional studyAnne Stuedal
Department of Nutrition, University of Oslo, Norway
Breast Cancer Res 8:R55. 2006..Leptin is a protein produced mainly by adipose tissue and may represent a growth factor in cancer. We examined the association between leptin plasma levels and mammographic density, a biomarker for breast cancer risk...
Hormone replacement therapy regimens and breast cancer risk(1)Linda K Weiss
Population Studies and Prevention Program, Karmanos Cancer Institute at Wayne State University, Detroit, Michigan, USA
Obstet Gynecol 100:1148-58. 2002..Progestin administered in an uninterrupted regimen may be a contributing factor. Risk dissipates once use is discontinued...
Projecting individualized absolute invasive breast cancer risk in African American womenMitchell H Gail
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Executive Plaza South Rm 8032, Bethesda, MD 20892 7244, USA
J Natl Cancer Inst 99:1782-92. 2007..We developed a model for projecting absolute risk of invasive breast cancer in African American women and compared its projections with those from the Breast Cancer Risk Assessment Tool...
Use of hormone therapy and risk of breast cancer detected at screening and between mammographic screensSolveig Hofvind
The Cancer Registry of Norway, Norway
Int J Cancer 118:3112-7. 2006..The increased risk of interval cancer, which may partly be due to decreased sensitivity of mammograms in HT users, remains a challenge in breast cancer screening programs...
Is there a positive association between mammographic density and bone mineral density? Authors' responseCarolyn Crandall
Breast Cancer Res 8:404. 2006
Relationship between established breast cancer risk factors and risk of seven different histologic types of invasive breast cancerChristopher I Li
Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 15:946-54. 2006....
Risk of breast cancer associated with short-term use of oral contraceptivesSuzanne G Folger
Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Cancer Causes Control 18:189-98. 2007..To estimate breast cancer risk associated with short-term (<6 months) oral contraceptive use, and explore variation in estimates by use characteristics and medical, menstrual, and reproductive history...
Insulin-like growth factor and mammographic density in postmenopausal Norwegian womenYngve Bremnes
Institute of Community Medicine, University of Tromsø, N 9037 Tromsø, Norway
Cancer Epidemiol Biomarkers Prev 16:57-62. 2007..These associations were found among noncurrent hormone therapy users but not among current users...
Different measures of smoking exposure and mammographic density in postmenopausal Norwegian women: a cross-sectional studyYngve Bremnes
Institute of Community Medicine, University of Tromsø, Tromsø, Norway
Breast Cancer Res 9:R73. 2007..Cigarette smoking may have both carcinogenic effects and antiestrogenic effects on the breast tissue. We decided to examine the relationship between different measures of smoking exposure and mammographic density...
Alcohol intake and breast cancer risk among young womenPaula Berstad
Institute of Basic Medical Sciences, Department of Nutrition, University of Oslo, Oslo, Norway
Breast Cancer Res Treat 108:113-20. 2008..Alcohol intake has been consistently associated with breast cancer risk, but the importance of timing of intake and the impact of beverage type are unclear...
Timing of menarche and first full-term birth in relation to breast cancer riskChristopher I Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Am J Epidemiol 167:230-9. 2008..The authors conclude that the interval between age at menarche and age at first birth is associated with the risk of hormonally sensitive types of breast cancer, particularly among White women...
Percentage density, Wolfe's and Tabár's mammographic patterns: agreement and association with risk factors for breast cancerInger T Gram
Institute of Community Medicine, University of Tromsø, Breivika, Norway
Breast Cancer Res 7:R854-61. 2005..The purpose of this report was to classify mammograms according to four methods and to examine their agreement and their relationship to selected risk factors for breast cancer...
Incomplete pregnancy is not associated with breast cancer risk: the California Teachers StudyKatherine Delellis Henderson
Department of Cancer Etiology, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA
Contraception 77:391-6. 2008..Several large prospective studies, which eliminate recall bias, did not detect associations, but this relationship continues to be debated...
Absence of an effect of injectable and implantable progestin-only contraceptives on subsequent risk of breast cancerBrian L Strom
Center for Clinical Epidemiology and Biostatistics and Department of Biostatistics and Epidemiology, 824 Blockley Hall, 423 Guardian Drive, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
Contraception 69:353-60. 2004..This study does not support an increased risk of breast cancer associated with the use of injectable or implantable progestin-only contraceptives in women aged 35 to 64...
Plasma levels of enterolactone and percentage mammographic density among postmenopausal womenAnne Stuedal
Department of Nutrition, University of Oslo, Norway
Cancer Epidemiol Biomarkers Prev 14:2154-9. 2005..Enterolactone has been shown to have weak estrogenic and antiestrogenic properties. We decided to examine the association between plasma levels of enterolactone and mammographic density, a biomarker for breast cancer risk...
Combined effect of oral contraceptive use and hormone replacement therapy on breast cancer risk in postmenopausal womenSandra A Norman
Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
Cancer Causes Control 14:933-43. 2003..We examined breast cancer risk related to lifetime exposure to oral contraceptives (OCs) and hormone replacement therapy (HRT) in postmenopausal women...
Reduced mammographic density with use of a gonadotropin-releasing hormone agonist-based chemoprevention regimen in BRCA1 carriersJeffrey N Weitzel
Department of Clinical Cancer Genetics, City of Hope Cancer Center, 1500 East Duarte Road, Duarte, CA 91010, USA
Clin Cancer Res 13:654-8. 2007..We evaluated the efficacy, safety, and tolerability of hormonal chemoprevention with a gonadotropin-releasing hormone agonist (GnRHA) with low-dose add-back steroids in BRCA1(mut) carriers...
Infertility drugs and the risk of breast cancer: findings from the National Institute of Child Health and Human Development Women's Contraceptive and Reproductive Experiences StudyRonald T Burkman
National Cancer Institute Surveillance, Epidemiology, and End Results Registry, Department of Obstetrics and Gynecology, Henry Ford Health System, Detroit, Michigan, USA
Fertil Steril 79:844-51. 2003..To determine the association between infertility drug use and invasive breast cancer in a population-based case-control study...
