Research Topics
Species | B B TysnesSummaryAffiliation: University of Bergen Country: Norway Publications
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Detail Information
Publications
Bromelain reversibly inhibits invasive properties of glioma cellsB B Tysnes
Department of Anatomy and Cell Biology, University of Bergen, Bergen N 5009, Norway
Neoplasia 3:469-79. 2001..These results indicate that bromelain exerts its antiinvasive effects by proteolysis, signaling cascades, and translational attenuation...
Epidermal growth factor and laminin receptors contribute to migratory and invasive properties of gliomasB B Tysnes
Department of Anatomy and Cell Biology, The Gade Institute, University of Bergen, Norway
Invasion Metastasis 17:270-80. 1997..These elements contribute to the characteristic features of glioma cells and may be an important part of the complex relationships between growth factors, integrins and extracellular matrix during glioma cell invasion...
Laminin expression by glial fibrillary acidic protein positive cells in human gliomasB B Tysnes
Department of Anatomy and Cell Biology, University of Bergen, Norway
Int J Dev Neurosci 17:531-9. 1999..This glycoprotein may thus represent one important substrate among many, which contribute to the invasive phenotype of gliomas...
Extracellular matrix-induced cell migration from glioblastoma biopsy specimens in vitroR Mahesparan
Department of Anatomy and Cell Biology, University of Bergen, Norway
Acta Neuropathol 97:231-9. 1999..Furthermore, the presented findings support the notion that gliomas may utilize different cell surface receptors for their migration, depending on the cell substrates available...
Biological mechanisms of glioma invasion and potential therapeutic targetsB B Tysnes
Department of Anatomy and Cell Biology, University of Bergen, Norway
J Neurooncol 53:129-47. 2001..This will hopefully render promising new therapeutic targets for gliomas...
Alginate-encapsulated producer cells: a potential new approach for the treatment of malignant brain tumorsF Thorsen
Department of Anatomy and Cell Biology, University of Bergen, Norway
Cell Transplant 9:773-83. 2000..Different producer cells may be encapsulated in alginate to target phenotypic features and microenvironmental factors, which may influence the progressive growth of brain tumors...
The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signalingM Chekenya
Norlux Neuro Oncology Group, Department of Biomedicine, University of Bergen, Bergen, Norway
Oncogene 27:5182-94. 2008..Thus, as a novel regulator of the antiapoptotic response, NG2/MPG may represent an effective therapeutic target in several cancer subtypes...
The glial precursor proteoglycan, NG2, is expressed on tumour neovasculature by vascular pericytes in human malignant brain tumoursM Chekenya
Department of Anatomy and Cell Biology, University of Bergen, Bergen, Norway
Neuropathol Appl Neurobiol 28:367-80. 2002..Thus, the expression of NG2 may be indicative of tumour progression and might be an amenable target for future therapeutic interventions...
Bromelain treatment leads to maturation of monocyte-derived dendritic cells but cannot replace PGE2 in a cocktail of IL-1β, IL-6, TNF-α and PGE2M Karlsen
Broegelmann Research Laboratory, The Gade Institute, University of Bergen, Bergen, Norway
Scand J Immunol 74:135-43. 2011..In conclusion, bromelain treatment of monocyte-derived DC does not improve the functional quality compared with the standard cytokine cocktail...
