Johan Svartberg

..In cases of macroprolactinomas, symptoms caused by local mass effects can be seen. A variety of other conditions may also cause hyperprolactinaemia; the goal of the examination is to identify the cause...

..We suggest that the reduction of total and free testosterone could be due to an alteration of the hypothalamic-pituitary response...

..Thus, smoking seems to be an important confounding factor when evaluating testosterone levels, and could possibly mask borderline hypogonadism...

..Thus, testosterone may have a protective role in the development of metabolic syndrome and subsequent diabetes mellitus and cardiovascular disease in aging men. However, clinical trials are needed to confirm this assumption...

..To study the relationship between endogenous sex hormone levels and intima-media thickness (IMT) of the carotid artery measured by ultrasonography...

..Older men with subnormal testosterone levels had an unfavorable metabolic profile. Testosterone treatment improved body composition, but it did not reverse the unfavorable metabolic profile...

..As arterial CVDs and venous thromboembolism (VTE) have been shown to share common risk factors, the purpose of the present study was to determine the impact of endogenous sex hormone levels on the incidence of VTE in a cohort of men...

..The purpose of this study was to examine the associations of vasomotor symptoms with risk of all-cause, cardiovascular disease (CVD), and coronary heart disease (CHD) mortality in community-dwelling older women, with a mean age of 69 years...

..Despite this uncertainty the sale of testosterone have increased enormously over the last few years, hence it seems important to discuss what we now know about such treatment...

..001). In the longitudinal study, however, LH levels did not predict changes in total and free testosterone levels. Thus, in clinical practice, measuring gonadotropins seems to be of limited value in detecting hypogonadism in ageing men...

..The variations in hormone levels were large, with a 31% difference between the lowest and highest monthly mean level of free testosterone. Prospective studies are needed to establish the direction of the association and its etiology...

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..Furthermore, there were no clinical or biochemical side effects...

..To evaluate the recent literature on the effect of the use of androgens in men with chronic obstructive pulmonary disease (COPD)...

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..To test the hypothesis that lower endogenous testosterone levels are associated with higher blood pressure, left ventricular mass, and left ventricular hypertrophy...

..To investigate changes in cardiovascular risk factors over 14 years in relation to diabetes status...

..To study the impact of endogenous sex hormone levels in community-dwelling men on later risk for type 2 diabetes...

..To study the relationships between endogenous testosterone, sex hormone-binding globulin (SHBG) and serum lipids in non-fasting men...

..The potential antithrombotic role of testosterone therapy remains to be elucidated...

..013) than those with only one component. In conclusion, there were no associations with GGN repeat length, while short CAG repeat length seems to be associated with increased risk of MS...

..We aimed to determine the clinical, immunological, and genetic features of a national registry-based cohort...

..2 to 87.1% (P value < 0.0001). One half of the incident cases of type 2 diabetes were missed by using high metabolic score for risk prediction...

..08-0.31%) for the lowest risk group.Conclusions: A family history of diabetes, elevated BMI, and high triglyceride levels identifies independent of cardiovascular risk factors, a group with especially high risk of T2DM. [corrected]..

..001). Men with chronic diseases had lower levels of DHEAS, compared with healthy men (P < 0.001). Smokers had higher DHEAS levels than nonsmokers. Further studies are needed to confirm these hormonal changes with age and disease...

..To investigate the level of postprandial triglycerides (TG)s in elderly men with subnormal testosterone level (< or = 11.0 nmol/L) compared to men with normal testosterone level (> 11.0 nmol/L)...

..To investigate the association between endogenous testosterone levels and psychological health symptoms in men from a general population...

..These findings indicate that when clinically evaluating T and LH levels in elderly men, the CAG and GGN repeat lengths do not need to be taken into consideration...

..Recently several single nucleotide polymorphisms (SNPs) associated with serum 25-hydroxyvitamin D (25(OH)D) level have been identified. If these relations are causal one would expect a similar association between these SNPs and health...

..To investigate the impact of testosterone supplementation on postprandial triglycerides in elderly men with subnormal endogenous testosterone...

..To study the impact of endogenous testosterone levels in community-dwelling men on later risk for myocardial infarction (MI) and all-cause, cardiovascular disease (CVD), and ischemic heart disease (IHD) mortality...

..In cross-sectional studies there appears to be a link between calcium metabolism and blood pressure, and most studies have found a positive association between serum parathyroid hormone (PTH) and hypertension...

..Among a substantial proportion of elderly subjects, and especially elderly women, the 2-hour plasma glucose was the only abnormal value...

..The present review focuses on the coagulation system and CVD from the perspective of testosterone...

..In conclusion, several SNPs related to calcium metabolism are associated with height, in particular rs3829251 at the DHCR7/NADSYN1 gene...

..Our findings suggest that low testosterone levels in elderly men is associated with low plasma free TFPI Ag and subsequent shortened initiation phase of TF-induced coagulation...

..Primary adrenal insufficiency (Addison's disease) is a rare autoimmune disease. Until recently, life expectancy in Addison's disease patients was considered normal...

..The lack of prospective associations in our study may be due to increased use of anti-hypertensive and lipid-lowering drugs from 1994 baseline to follow-up...

..In conclusion, blood pressure and serum PTH are associated. This association cannot be explained by the urinary calcium excretion alone...

..001 and p<0.01, respectively).CONCLUSION: Lower levels of total testosterone and SHBG were associated with increased HbA1c levels and diabetes independent of concomitant variations in obesity and body fat distribution...

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..000-40.000 IU per week) and 37 subjects given placebo...

..In conclusion, a deranged calcium metabolism appears to be associated with impaired function in several tests of neuropsychological function...

..One possible explanation, besides the difference in climate, for the diverging findings between our previous study and the present study is different sleep patterns...

..A possible explanation of the excess cardiovascular risk in testicular cancer (TC) survivors is development of metabolic syndrome. The association between metabolic syndrome and TC treatment is examined in long-term survivors...

..Successful parathyroidectomy quickly relieves symptoms and prevents recurrence...

..Fractionated single beam irradiation or stereotactic radiosurgery is indicated in cases where there is a residual of growing tumours that may not be removed surgically...

..The aim of this study was to determine whether radiotherapy for rectal cancer affects testosterone production...

..2 mg in one dose per day. Treatment with 20 - 50 mg dehydroepiandrosterone has been studied in adrenal failure, but the evidence for positive effects is weak, and it can not be recommended as standard treatment in primary adrenal failure...

..New diagnostic procedures make today's assessment more accurate. We describe which tests should be done when there is suspicion of the syndrome. Treatment options are mentioned...

..Surgery is the primary treatment of acromegaly. However, it often fails to cure the patient. New strategies that improve surgical outcome are needed...