Affiliation: University of Oslo
- Resuscitation with supplementary oxygen induces oxidative injury in the cerebral cortexRønnaug Solberg
Department of Pediatric Research, University of Oslo, Oslo University Hospital, Rikshospitalet, N 0424 Oslo, Norway
Free Radic Biol Med 53:1061-7. 2012..These novel findings provide new knowledge regarding the relationships between oxidative brain injury and resuscitation with oxygen...
- Resuscitation of hypoxic newborn piglets with supplementary oxygen induces dose-dependent increase in matrix metalloproteinase-activity and down-regulates vital genesRønnaug Solberg
Department of Paediatric Research, University of Oslo, Oslo University Hospital, Rikshospitalet, Oslo, Norway
Pediatr Res 67:250-6. 2010..MMP-, VEGF-, and TGFbeta-superfamily are vital for the development, growth, and functional integrity of most tissues and our data rise concern about both short- and long-term consequences of even a brief hyperoxic exposure...
- Resuscitation of hypoxic newborn piglets with oxygen induces a dose-dependent increase in markers of oxidationRønnaug Solberg
Department of Pediatric Research, Medical Faculty, University of Oslo Rikshospitalet Medical Centre, Oslo, N 0027, Norway
Pediatr Res 62:559-63. 2007..The increase in the hydroxyl attack may lead to a pro-oxidative status and risk for genetic instability...
- Resuscitation of newborn piglets. short-term influence of FiO2 on matrix metalloproteinases, caspase-3 and BDNFRønnaug Solberg
Department of Paediatric Research, University of Oslo and Oslo University Hospital, Rikshospitalet, Oslo, Norway
PLoS ONE 5:e14261. 2010....
- Resuscitation with 21 or 100% oxygen in hypoxic nicotine-pretreated newborn piglets: possible neuroprotective effects of nicotineJannicke H Andresen
Department of Pediatric Research, Medical Faculty, University of Oslo, Rikshospitalet Radiumhospitalet Medical Center, Oslo, Norway
Neonatology 93:36-44. 2008..Perinatal asphyxia is a major concern in perinatal medicine. Resuscitation and ways to prevent and minimize adverse outcomes after perinatal asphyxia are subject to extensive research...
- Newborn piglets exposed to hypoxia after nicotine or saline pretreatment: long-term effects on brain and heartJannicke H Andresen
Medical Faculty, Department of Pediatric Research, Rikshospitalet University Hospital, University of Oslo, Oslo, Norway
J Matern Fetal Neonatal Med 22:161-8. 2009..Hypothesising that nicotine might give a better outcome because of its anti-apoptotic and anti-inflammatory effects...
- Oxygenation of the newborn: a molecular approachOla Didrik Saugstad
Department of Pediatric Research, Women and Children s Division, Oslo University Hospital, University of Oslo, Oslo, Norway
Neonatology 101:315-25. 2012..In the postnatal period the oxygen saturation should be targeted low <95%; however, saturations between 85 and 89% seem to increase mortality. The optimal oxygen saturation target for these infants postnatally is still unknown...
- Metabolomic analyses of plasma reveals new insights into asphyxia and resuscitation in pigsRønnaug Solberg
Department of Pediatric Research, Oslo University Hospital, Rikshospitalet, University of Oslo, Norway
PLoS ONE 5:e9606. 2010..We hypothesized that the quantification of metabolites after hypoxia and resuscitation would enable the detection of markers of hypoxia as well as markers enabling the monitoring and evaluation of resuscitation strategies...
- Resuscitation of newborn infants with 21% or 100% oxygen: follow-up at 18 to 24 monthsOla D Saugstad
Department of Pediatric Research, Rikshospitalet, University of Oslo, Oslo, Norway
Pediatrics 112:296-300. 2003..To follow-up children who had been resuscitated at birth with either 21% or 100% oxygen (O2)...
- Improved cognitive development among preterm infants attributable to early supplementation of human milk with docosahexaenoic acid and arachidonic acidChristine Henriksen
Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Norway
Pediatrics 121:1137-45. 2008..The objective of our study was to evaluate the effect of supplementation with docosahexaenoic acid and arachidonic acid for human milk-fed preterm infants. The primary end point was cognitive development at 6 months of age...