T Sagvolden

Summary

Affiliation: University of Oslo
Country: Norway

Publications

  1. pmc Postnatal exposure to PCB 153 and PCB 180, but not to PCB 52, produces changes in activity level and stimulus control in outbred male Wistar Kyoto rats
    Espen Borgå Johansen
    Department of Physiology, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
    Behav Brain Funct 7:18. 2011
  2. pmc Intraindividual variability (IIV) in an animal model of ADHD - the Spontaneously Hypertensive Rat
    Guy M L Perry
    Department of Medicine, SUNY Upstate Medical University, Syracuse, NY 13210, USA
    Behav Brain Funct 6:56. 2010
  3. pmc Origins of altered reinforcement effects in ADHD
    Espen Borgå Johansen
    Centre for Advanced Study CAS at the Norwegian Academy for Science and Letters, Oslo, Norway
    Behav Brain Funct 5:7. 2009
  4. pmc Behavioral variability, elimination of responses, and delay-of-reinforcement gradients in SHR and WKY rats
    Espen B Johansen
    Department of Physiology, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
    Behav Brain Funct 3:60. 2007
  5. pmc The spontaneously hypertensive rat model of ADHD--the importance of selecting the appropriate reference strain
    Terje Sagvolden
    Institute of Basic Medical Sciences, University of Oslo, Norway
    Neuropharmacology 57:619-26. 2009
  6. pmc l-Amphetamine improves poor sustained attention while d-amphetamine reduces overactivity and impulsiveness as well as improves sustained attention in an animal model of Attention-Deficit/Hyperactivity Disorder (ADHD)
    Terje Sagvolden
    Institute of Basic Medical Sciences, Department of Physiology, University of Oslo, PO Box 1103 Blindern, NO 0317 Oslo, Norway
    Behav Brain Funct 4:3. 2008
  7. pmc Behavioral and genetic evidence for a novel animal model of Attention-Deficit/Hyperactivity Disorder Predominantly Inattentive Subtype
    T Sagvolden
    Department of Physiology, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
    Behav Brain Funct 4:56. 2008
  8. ncbi A dynamic developmental theory of attention-deficit/hyperactivity disorder (ADHD) predominantly hyperactive/impulsive and combined subtypes
    Terje Sagvolden
    Department of Physiology, University of Oslo, NO 0317 Oslo, Norway
    Behav Brain Sci 28:397-419; discussion 419-68. 2005
  9. ncbi Rodent models of attention-deficit/hyperactivity disorder
    Terje Sagvolden
    Center for Advanced Study at the Norwegian Academy of Science and Letters, Department of Physiology, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
    Biol Psychiatry 57:1239-47. 2005
  10. pmc The neuroscience peer review consortium
    Clifford B Saper
    Behavioral and Brain Functions, University of Oslo, Oslo, Norway
    Behav Brain Funct 5:4. 2009

Collaborators

Detail Information

Publications27

  1. pmc Postnatal exposure to PCB 153 and PCB 180, but not to PCB 52, produces changes in activity level and stimulus control in outbred male Wistar Kyoto rats
    Espen Borgå Johansen
    Department of Physiology, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
    Behav Brain Funct 7:18. 2011
    ..67 s), and responses with short IRTs (< 0.67 s)...
  2. pmc Intraindividual variability (IIV) in an animal model of ADHD - the Spontaneously Hypertensive Rat
    Guy M L Perry
    Department of Medicine, SUNY Upstate Medical University, Syracuse, NY 13210, USA
    Behav Brain Funct 6:56. 2010
    ....
  3. pmc Origins of altered reinforcement effects in ADHD
    Espen Borgå Johansen
    Centre for Advanced Study CAS at the Norwegian Academy for Science and Letters, Oslo, Norway
    Behav Brain Funct 5:7. 2009
    ..Theoretical and experimental analyses of these moderating factors will help to determine just how reinforcement processes are altered in ADHD. Such analyses can only help to improve treatment strategies for ADHD...
  4. pmc Behavioral variability, elimination of responses, and delay-of-reinforcement gradients in SHR and WKY rats
    Espen B Johansen
    Department of Physiology, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
    Behav Brain Funct 3:60. 2007
    ..abstract:..
  5. pmc The spontaneously hypertensive rat model of ADHD--the importance of selecting the appropriate reference strain
    Terje Sagvolden
    Institute of Basic Medical Sciences, University of Oslo, Norway
    Neuropharmacology 57:619-26. 2009
    ..Finally, we argue that WKY rats obtained from Charles River, Germany (WKY/NCrl) provide a promising model for the predominantly inattentive subtype of ADHD (ADHD-PI); in this case also the WKY/NHsd substrain should be used as control...
  6. pmc l-Amphetamine improves poor sustained attention while d-amphetamine reduces overactivity and impulsiveness as well as improves sustained attention in an animal model of Attention-Deficit/Hyperactivity Disorder (ADHD)
    Terje Sagvolden
    Institute of Basic Medical Sciences, Department of Physiology, University of Oslo, PO Box 1103 Blindern, NO 0317 Oslo, Norway
    Behav Brain Funct 4:3. 2008
    ..abstract:..
  7. pmc Behavioral and genetic evidence for a novel animal model of Attention-Deficit/Hyperactivity Disorder Predominantly Inattentive Subtype
    T Sagvolden
    Department of Physiology, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
    Behav Brain Funct 4:56. 2008
    ..abstract:..
  8. ncbi A dynamic developmental theory of attention-deficit/hyperactivity disorder (ADHD) predominantly hyperactive/impulsive and combined subtypes
    Terje Sagvolden
    Department of Physiology, University of Oslo, NO 0317 Oslo, Norway
    Behav Brain Sci 28:397-419; discussion 419-68. 2005
    ..The theory describes how individual predispositions interact with these conditions to produce behavioral, emotional, and cognitive effects that can turn into relatively stable behavioral patterns...
  9. ncbi Rodent models of attention-deficit/hyperactivity disorder
    Terje Sagvolden
    Center for Advanced Study at the Norwegian Academy of Science and Letters, Department of Physiology, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
    Biol Psychiatry 57:1239-47. 2005
    ....
  10. pmc The neuroscience peer review consortium
    Clifford B Saper
    Behavioral and Brain Functions, University of Oslo, Oslo, Norway
    Behav Brain Funct 5:4. 2009
    ..In order to encourage dissemination of the details outlined in this Editorial, it will also be published in other journals in the Neuroscience Peer Review Consortium...
  11. doi Rat models of ADHD
    Terje Sagvolden
    Department of Physiology, Institute of Basic Medical Sciences, University of Oslo, NO 0317, Oslo, Norway
    Curr Top Behav Neurosci 9:301-15. 2012
    ..Finally, model data yield support to independent hyperactivity and inattention dimensions in ADHD behavior...
  12. pmc Impulsiveness, overactivity, and poorer sustained attention improve by chronic treatment with low doses of l-amphetamine in an animal model of Attention-Deficit/Hyperactivity Disorder (ADHD)
    Terje Sagvolden
    Institute of Basic Medical Sciences, Department of Physiology, University of Oslo, Blindern, NO 0317 Oslo, Norway
    Behav Brain Funct 7:6. 2011
    ..The primary objective of the present research was to investigate behavioral effects of a range of doses of chronic l-amphetamine on ADHD-like symptoms in the SHR...
  13. ncbi Chronic L-deprenyl treatment alters brain monoamine levels and reduces impulsiveness in an animal model of Attention-Deficit/Hyperactivity Disorder
    F Boix
    Department of Neurophysiology, University of Oslo, Norway
    Behav Brain Res 94:153-62. 1998
    ..The positive effect of L-deprenyl on impulsiveness is discussed as due either to normalization of an asymmetric dopaminergic activity in the nucleus accumbens, or to a restoration of normal DA function in the prefrontal cortex...
  14. ncbi Response disinhibition may be explained as an extinction deficit in an animal model of attention-deficit/hyperactivity disorder (ADHD)
    Espen Borgå Johansen
    Department of Physiology, University of Oslo, P O Box 1103, Blindern, 0317 Oslo, Norway
    Behav Brain Res 149:183-96. 2004
    ..The extinction deficit in the SHR may be linked to reinforcer unpredictability and the presence of conditioned reinforcers, and may explain response disinhibition seen in children with ADHD...
  15. ncbi Low dopamine D5 receptor density in hippocampus in an animal model of attention-deficit/hyperactivity disorder (ADHD)
    T Medin
    The Brain and Muscle Energy Group, Centre for Molecular Biology and Neuroscience and Department of Anatomy, Institute of Basic Medical Sciences, University of Oslo, Pb 1105 Blindern, N 0317 Oslo, Norway
    Neuroscience 242:11-20. 2013
    ..DRs are important for long-term potentiation and long-term depression, hence the deficit may contribute to the learning difficulties in individuals with the diagnosis of ADHD...
  16. doi Dopamine D5 receptors are localized at asymmetric synapses in the rat hippocampus
    T Medin
    The Brain and Muscle Energy Group, Centre for Molecular Biology and Neuroscience and Department of Anatomy, Institute of Basic Medical Sciences, University of Oslo, PB1105 Blindern, N 0317 Oslo, Norway
    Neuroscience 192:164-71. 2011
    ....
  17. ncbi Behavioral validation of the spontaneously hypertensive rat (SHR) as an animal model of attention-deficit/hyperactivity disorder (AD/HD)
    T Sagvolden
    Department of Physiology, University of Oslo, Norway
    Neurosci Biobehav Rev 24:31-9. 2000
    ..This does not mean that investigating other models cannot give valuable information...
  18. doi N-methyl-D-aspartate receptor subunit dysfunction at hippocampal glutamatergic synapses in an animal model of attention-deficit/hyperactivity disorder
    V Jensen
    Molecular Neurobiology Research Group, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
    Neuroscience 158:353-64. 2009
    ..The results indicate that functional impairments in glutamatergic synaptic transmission may be one of the underlying mechanisms leading to the abnormal behavior in SHR, and possibly in human ADHD...
  19. ncbi Effects of delayed reinforcers on the behavior of an animal model of attention-deficit/hyperactivity disorder (ADHD)
    Espen Borgå Johansen
    Department of Physiology, University of Oslo, P O Box 1003, Blindern, N 0317 Oslo, Norway
    Behav Brain Res 162:47-61. 2005
    ..In general, the results support predictions from the suggested steepened delay gradient in SHR. However, the predictions were only partly confirmed by the analyses of the decay parameter...
  20. ncbi Behavioral effects of intra-cranial self-stimulation in an animal model of attention-deficit/hyperactivity disorder (ADHD)
    Espen Borgå Johansen
    Department of Physiology, University of Oslo, P O Box 1103, Blindern, 0317 Oslo, Norway
    Behav Brain Res 162:32-46. 2005
    ..Overall, more responses with short inter-response times (IRT) were found in the SHR compared to the controls during intermittent reinforcement. The results are consistent with a steepened delay-of-reinforcement gradient in SHR...
  21. ncbi Slower extinction of responses maintained by intra-cranial self-stimulation (ICSS) in an animal model of attention-deficit/hyperactivity disorder (ADHD)
    Espen Borgå Johansen
    Department of Physiology, University of Oslo, Norway Centre for Advanced Study, P O Box 1103 Blindern, 0317 Oslo, Norway
    Behav Brain Res 162:22-31. 2005
    ..Slower extinction of previously reinforced behavior is suggested as an alternative explanation for the frequently observed increased behavioral output that has previously been interpreted as "disinhibition" of behavior in ADHD...
  22. ncbi Open-field behavior of rats previously subjected to short-term hyperbilirubinemia with or without blood-brain barrier manipulations
    T W Hansen
    Department of Pediatric Research, National Hospital, University of Oslo, Norway
    Brain Res 424:26-36. 1987
    ..The sequelae of bilirubin brain toxicity appear to include changes in stimulus processing. This is compatible with findings from neuropsychological tests of children who have had significant neonatal hyperbilirubinemia...
  23. ncbi Infrequent, but not frequent, reinforcers produce more variable responding and deficient sustained attention in young children with attention-deficit/hyperactivity disorder (ADHD)
    Heidi Aase
    Norwegian Center for Studies of Conduct Problems and Innovative Practice, UNIRAND Ltd, University of Oslo, Norway
    J Child Psychol Psychiatry 47:457-71. 2006
    ..The present study was designed to analyze the influence of reinforcement frequency on operationalized measures of hyperactivity, impulsiveness, sustained attention, and response variability...
  24. ncbi Short term storage of samples containing monoamines: ascorbic acid and glutathione give better protection against degradation than perchloric acid
    F Boix
    Department of Physiology, National Institute of Occupational Health, Oslo, Norway
    J Neurosci Methods 75:69-73. 1997
    ..Perchloric acid actually accelerated the degradation of 5-HIAA...
  25. ncbi Attention-deficit/hyperactivity disorder (ADHD) behaviour explained by dysfunctioning reinforcement and extinction processes
    Espen Borgå Johansen
    Department of Physiology, University of Oslo, PO Box 1103 Blindern, N 0317 Oslo, Norway
    Behav Brain Res 130:37-45. 2002
    ..Etiologically, dopamine dysfunctioning will probably mainly be genetically determined while sometimes be induced by environmental factors like drugs of abuse or pollutants, which may explain geographical differences in prevalence rates...
  26. ncbi The control of responsiveness in ADHD by catecholamines: evidence for dopaminergic, noradrenergic and interactive roles
    Robert D Oades
    Clinic for Child and Adolescent Psychiatry, University of Duisburg Essen, Germany
    Dev Sci 8:122-31. 2005
    ..Recent insights into the previously underestimated role of the NA system in the control of mesocortical DA function, and the frontal role in processing information are elaborated...