M Raki

Summary

Affiliation: University of Oslo
Country: Norway

Publications

  1. doi request reprint Plasmacytoid dendritic cells are scarcely represented in the human gut mucosa and are not recruited to the celiac lesion
    M Raki
    Centre for Immune Regulation and Department of Immunology, Oslo University Hospital Rikshospitalet, Oslo, Norway
    Mucosal Immunol 6:985-92. 2013
  2. pmc The effects of atorvastatin on gluten-induced intestinal T cell responses in coeliac disease
    M Raki
    Institute of Immunology, University of Oslo, Rikshospitalet University Hospital, Norway
    Clin Exp Immunol 142:333-40. 2005
  3. ncbi request reprint A unique dendritic cell subset accumulates in the celiac lesion and efficiently activates gluten-reactive T cells
    Melinda Raki
    Institute of Immunology, University of Oslo, Rikshospitalet Radiumhospitalet Medical Center, Oslo, Norway
    Gastroenterology 131:428-38. 2006
  4. pmc Tetramer visualization of gut-homing gluten-specific T cells in the peripheral blood of celiac disease patients
    Melinda Raki
    Institute of Immunology, University of Oslo, Rikshospitalet Radiumhospitalet Medical Center, 0027 Oslo, Norway
    Proc Natl Acad Sci U S A 104:2831-6. 2007
  5. ncbi request reprint Surface expression of transglutaminase 2 by dendritic cells and its potential role for uptake and presentation of gluten peptides to T cells
    M Raki
    Institute of Immunology, The Pathology Clinic, Rikshospitalet Radiumhospitalet Medical Center, University of Oslo, Oslo, Norway
    Scand J Immunol 65:213-20. 2007
  6. doi request reprint Density of CD163+ CD11c+ dendritic cells increases and CD103+ dendritic cells decreases in the coeliac lesion
    A C R Beitnes
    Centre for Immune Regulation, Institute of Immunology, Oslo University Hospital, Rikshospitalet, Oslo, Norway
    Scand J Immunol 74:186-94. 2011
  7. doi request reprint HLA-DQ2-restricted gluten-reactive T cells produce IL-21 but not IL-17 or IL-22
    M Bodd
    Centre for Immune Regulation, Institute of Immunology, University of Oslo and Oslo University Hospital Rikshospitalet, Oslo, Norway
    Mucosal Immunol 3:594-601. 2010

Detail Information

Publications7

  1. doi request reprint Plasmacytoid dendritic cells are scarcely represented in the human gut mucosa and are not recruited to the celiac lesion
    M Raki
    Centre for Immune Regulation and Department of Immunology, Oslo University Hospital Rikshospitalet, Oslo, Norway
    Mucosal Immunol 6:985-92. 2013
    ..IFN-λ, a type III IFN important in intestinal antiviral defense, was produced mainly by APCs, but its expression was not increased in the celiac lesion...
  2. pmc The effects of atorvastatin on gluten-induced intestinal T cell responses in coeliac disease
    M Raki
    Institute of Immunology, University of Oslo, Rikshospitalet University Hospital, Norway
    Clin Exp Immunol 142:333-40. 2005
    ..In conclusion, atorvastatin has specific effects on isolated gluten-reactive T cells and dendritic cells, but does not shut down the gluten-induced production of proinflammatory cytokines in intestinal biopsies...
  3. ncbi request reprint A unique dendritic cell subset accumulates in the celiac lesion and efficiently activates gluten-reactive T cells
    Melinda Raki
    Institute of Immunology, University of Oslo, Rikshospitalet Radiumhospitalet Medical Center, Oslo, Norway
    Gastroenterology 131:428-38. 2006
    ..The aim of this study was to identify the antigen-presenting cells that are responsible for the activation of gluten-reactive T cells in the celiac lesion...
  4. pmc Tetramer visualization of gut-homing gluten-specific T cells in the peripheral blood of celiac disease patients
    Melinda Raki
    Institute of Immunology, University of Oslo, Rikshospitalet Radiumhospitalet Medical Center, 0027 Oslo, Norway
    Proc Natl Acad Sci U S A 104:2831-6. 2007
    ..Most of the cells had a memory phenotype, but many other phenotypic markers showed a heterogeneous pattern. Tetramer staining of gluten-specific T cells has the potential to be used for diagnosis of celiac disease...
  5. ncbi request reprint Surface expression of transglutaminase 2 by dendritic cells and its potential role for uptake and presentation of gluten peptides to T cells
    M Raki
    Institute of Immunology, The Pathology Clinic, Rikshospitalet Radiumhospitalet Medical Center, University of Oslo, Oslo, Norway
    Scand J Immunol 65:213-20. 2007
    ..However, we were unable to obtain evidence for a role of surface TG2 in the loading and subsequent generation of deamidated gluten peptides in these cells...
  6. doi request reprint Density of CD163+ CD11c+ dendritic cells increases and CD103+ dendritic cells decreases in the coeliac lesion
    A C R Beitnes
    Centre for Immune Regulation, Institute of Immunology, Oslo University Hospital, Rikshospitalet, Oslo, Norway
    Scand J Immunol 74:186-94. 2011
    ....
  7. doi request reprint HLA-DQ2-restricted gluten-reactive T cells produce IL-21 but not IL-17 or IL-22
    M Bodd
    Centre for Immune Regulation, Institute of Immunology, University of Oslo and Oslo University Hospital Rikshospitalet, Oslo, Norway
    Mucosal Immunol 3:594-601. 2010
    ..We conclude that gluten-reactive T cells produce IL-21 and IFN-γ, but not IL-17. Their production of IL-21 suggests a role for this cytokine in the pathogenesis of celiac disease...