Research Topics
Genomes and GenesSpecies | S OrstavikSummaryAffiliation: University of Oslo Country: Norway Publications
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Detail Information
Publications
Characterization of the human gene encoding the type I alpha and type I beta cGMP-dependent protein kinase (PRKG1)S Orstavik
Institute of Medical Biochemistry, University of Oslo, Norway
Genomics 42:311-8. 1997..Northern blot analyses demonstrated distinct patterns of expression of the isoforms of type I alpha and I beta cGK in different human tissues...
Identification, cloning and characterization of a novel nuclear protein, HA95, homologous to A-kinase anchoring protein 95S Orstavik
Institute of Medical Biochemistry, Faculty of Medicine, University of Oslo, Norway
Biol Cell 92:27-37. 2000..The similarity in sequence and localization of HA95 and AKAP95 suggests that the two molecules constitute a novel family of nuclear proteins that may exhibit related functions...
Cloning and characterization of a cDNA encoding an A-kinase anchoring protein located in the centrosome, AKAP450O Witczak
Institute of Medical Biochemistry, Faculty of Medicine, University of Oslo, PO Box 1112, Blindern N 0317 Oslo, Norway
EMBO J 18:1858-68. 1999..Furthermore, AKAP450 was shown to co-purify in centrosomal preparations. The observation of two mRNAs and several splice products suggests additional functions for the AKAP450 gene...
Molecular cloning, cDNA structure, and chromosomal localization of the human type II cGMP-dependent protein kinaseS Orstavik
Institute of Medical Biochemistry, Faculty of Medicine, University of Oslo, Norway
Biochem Biophys Res Commun 220:759-65. 1996..By using polymerase chain reaction and Southern blotting on somatic cell hybrids, the gene encoding, the type II cGMP-dependent protein kinase was mapped to human chromosome 4q13.1-q21.1...
A novel isoform of human cyclic 3',5'-adenosine monophosphate-dependent protein kinase, c alpha-s, localizes to sperm midpieceN Reinton
Institute of Medical Biochemistry, University of Oslo, N 0317 Oslo, Norway
Biol Reprod 63:607-11. 2000..This novel C alpha-s splice variant appeared to have an independent anchor in the human sperm midpiece as it could not be completely solubilized even in the presence of both detergent and cAMP...
Characterization of the gene encoding the human type II cGMP-dependent protein kinaseO Witczak
Institute of Medical Biochemistry, University of Oslo, Oslo, N 0317, Norway
Biochem Biophys Res Commun 245:113-9. 1998..5'-rapid amplification of cDNA-ends established the presence of a non-translated exon...
Novel alternatively spliced mRNA (1c) of the protein kinase A RIα subunit is implicated in haploid germ cell specific expressionM K Dahle
Institute of Medical Biochemistry, University of Oslo, Oslo, Norway
Mol Reprod Dev 59:11-6. 2001..The RIalpha 1c haploid-specific mRNA, therefore, may be important for the regulation of RIalpha expression in sperm...
The gene encoding the C gamma catalytic subunit of cAMP-dependent protein kinase is a transcribed retroposonN Reinton
Institute of Medical Biochemistry, University of Oslo, Norway
Genomics 49:290-7. 1998..Our results indicate that the C gamma gene is a retroposon specifically transcribed in primate testicular germ cells...
Identification of a human member of the Ly-49 multigene familyI H Westgaard
Department of Anatomy, Institute of Basic Medical Sciences, University of Oslo, Norway
Eur J Immunol 28:1839-46. 1998..Southern blot analysis of genomic DNA showed a simple pattern with a full-length Ly-49L probe at low stringency hybridization conditions, suggesting that Ly-49L may be the only human member of the Ly-49 multigene family...
Structural and functional organization of the gene encoding the human thyrotropin-releasing hormone receptorV Matre
Institute of Medical Biochemistry, University of Oslo, Norway
J Neurochem 72:40-50. 1999..Functional analysis of potential response elements for the anterior pituitary-specific transcription factor Pit-1 revealed cell type-specific binding that was competed out with a Pit-1 response element from the GH gene promoter...
Molecular cloning, chromosomal localization, and cell cycle-dependent subcellular distribution of the A-kinase anchoring protein, AKAP95T Eide
Institute of Medical Biochemistry, University of Oslo, Blindern, Oslo, N 0317, Norway
Exp Cell Res 238:305-16. 1998..The results show a distinct redistribution of AKAP95 during mitosis, suggesting that the interaction between AKAP95 and RIIalpha may be cell cycle-dependent...
Localization of the human gene for the type I cyclic GMP-dependent protein kinase to chromosome 10S Orstavik
Institute of Medical Biochemistry, Rikshospitalet, University of Oslo, Norway
Cytogenet Cell Genet 59:270-3. 1992..2----q11.2...
Molecular cloning of the cDNA encoding pp36, a tyrosine-phosphorylated adaptor protein selectively expressed by T cells and natural killer cellsJ R Weber
Department of Medicine and Rosalind Russell Arthritis Center, University of California, San Francisco, California 94143, USA
J Exp Med 187:1157-61. 1998..Molecular cloning of the gene encoding pp36 should facilitate studies examining the role of this adaptor protein in proximal signaling events during T and NK cell activation...
