Research Topics
Species | Dag Rune OlsenSummaryAffiliation: University of Oslo Country: Norway Publications
| Collaborators
|
Detail Information
Publications
Principal component analysis for the comparison of metabolic profiles from human rectal cancer biopsies and colorectal xenografts using high-resolution magic angle spinning 1H magnetic resonance spectroscopyTherese Seierstad
Department of Medical Physics, Rikshospitalet Radiumhospitalet Medical Center, 0310 Oslo, Norway
Mol Cancer 7:33. 2008..A further aim was to investigate metabolic changes following irradiation of HT29 xenografts...
Proton therapy - a systematic review of clinical effectivenessDag Rune Olsen
Rikshospitalet Radiumhospitalet Medical Center, University of Oslo, Oslo, Norway
Radiother Oncol 83:123-32. 2007..Several proton facilities are currently operating or under planning world-wide - in the United States, Asia and Europe. Until now no systematic review assessing the clinical effectiveness of this treatment modality has been published...
Strategies for biologic image-guided dose escalation: a reviewAste Søvik
Department of Radiation Biology, Institute for Cancer Research, Rikshospitalet University Hospital, Oslo, Norway
Int J Radiat Oncol Biol Phys 73:650-8. 2009..We conclude with a summary of the current status of biologic image-based dose escalation and of areas where further work is needed for this strategy to become incorporated into clinical practice...- Mechanisms of the elimination of low dose hyper-radiosensitivity in T-47D cells by low dose-rate primingNina Jeppesen Edin
Department of Physics, University of Oslo, Biophysics Group, PB 1048 Blindern, N 0316 Oslo, Norway
Int J Radiat Biol 85:1157-65. 2009..To investigate the mechanisms of elimination of low-dose hyper-radiosensitivity (HRS) in T-47D cells induced by 0.3 Gy low dose-rate (LDR) priming... - Low dose hyper-radiosensitivity is eliminated during exposure to cycling hypoxia but returns after reoxygenationNina Jeppesen Edin
Department of Physics, University of Oslo, Norway
Int J Radiat Biol 88:311-9. 2012..The presence of HRS in response to subsequent challenge irradiation was measured by clonogenic survival... - Late regional density changes of the lung after radiotherapy for breast cancerRandi Vågane
Department of Radiation Biology, Institute for Cancer Research, Rikshospitalet University Hospital, Oslo, Norway
Radiother Oncol 90:148-52. 2009..To investigate density changes in lung tissue, 3-4 years after postoperative adjuvant radiotherapy for breast cancer, based on dose dependence and regional differences... - A planning comparison of dose patterns in organs at risk and predicted risk for radiation induced malignancy in the contralateral breast following radiation therapy of primary breast using conventional, IMRT and volumetric modulated arc treatment techniquSafora Johansen
Institute for Cancer Research, Norwegian Radium Hospital, Rikshospitalet University Hospital, Oslo, Norway
Acta Oncol 48:495-503. 2009..Furthermore, to predict the risk for induced malignancies in CB using linear and non linear models... - Radiotherapy adapted to spatial and temporal variability in tumor hypoxiaAste Søvik
Department of Medical Physics, The Norwegian Radium Hospital, Oslo, Norway
Int J Radiat Oncol Biol Phys 68:1496-504. 2007..To explore the feasibility and clinical potential of adapting radiotherapy to temporal and spatial variations in tumor oxygenation... - Estimated risk for secondary cancer in the contra-lateral breast following radiation therapy of breast cancerSafora Johansen
Department of Medical Physics, Rikshospitalet Radiumhospitalet Medical Centre, Oslo, Norway
Acta Oncol 47:391-6. 2008..To facilitate a discussion about the impact of dose heterogeneity on the risk for secondary contralateral breast (CB) cancer predicted with linear and non linear models associated with primary breast irradiation... - DCEMRI of spontaneous canine tumors during fractionated radiotherapy: a pharmacokinetic analysisSte Søvik
Department of Radiation Biology, Oslo University Hospital, Oslo, Norway
Radiother Oncol 93:618-24. 2009.... - Adapting biological feedback in radiotherapyAste Søvik
Department of Radiation Biology, Institute for Cancer Research, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway
Semin Radiat Oncol 20:138-46. 2010..Finally, we discuss to what degree biologically adapted radiotherapy may be expected to improve treatment outcome and which issues need to be resolved for this strategy to reach its full potential... - Improved image quality of low-dose thoracic CT examinations with a new postprocessing softwareAnne Catrine Tregde Martinsen
The Interventional Centre, Oslo University Hospital, Oslo, Norway
J Appl Clin Med Phys 11:3242. 2010..2, 0.1 and 0.3 for the full-dose, low-dose and low-dose enhanced series, respectively. There is a potential for improving diagnostic performance of low-dose CT chest examinations using this new postprocessing filter... - Automatic segmentation and recognition of lungs and lesion from CT scans of thoraxManish Kakar
Department of Radiation Biology, Institute for Cancer Research, Rikshospitalet Radiumhospitalet Medical Centre, Oslo, Norway
Comput Med Imaging Graph 33:72-82. 2009..Results reveal an accuracy of delineation to be 94.06%, 94.32% and 89.04% for left lung, right lung and lesion, respectively. Average sensitivity of the SVM classifier was seen to be 89.48%... - Late effects after radiotherapy for locally advanced cervical cancer: comparison of two brachytherapy schedules and effect of dose delivered weeklyTaran Paulsen Hellebust
Department of Medical Physics, Division of Cancer Medicine and Radiotherapy, Institute for Cancer Research, Radiumhospitalet, Rikshospitalet University Hospital, Oslo, Norway
Int J Radiat Oncol Biol Phys 76:713-8. 2010.... - Longitudinal magnetic resonance imaging-based assessment of vascular changes and radiation response in androgen-sensitive prostate carcinoma xenografts under androgen-exposed and androgen-deprived conditionsKathrine Røe
Department of Radiation Biology, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway
Neoplasia 12:818-25. 2010.... - Dose evaluation and risk estimation for secondary cancer in contralateral breast and a study of correlation between thorax shape and dose to organs at risk following tangentially breast irradiation during deep inspiration breath-hold and free breathingSafora Johansen
Institute for Cancer Research, Oslo University Hospital, Oslo, Norway
Acta Oncol 50:563-8. 2011.... - Quantification of angiogenesis in breast cancer by automated vessel identification in CD34 immunohistochemical sectionsLars Tore Gyland Mikalsen
Department of Physics, University of Oslo, Postboks 1048 Blindern, N 0316, Oslo, Norway
Anticancer Res 31:4053-60. 2011..We present a method of automatic vessel identification applied to CD34 immunohistochemical sections which facilitates increased reproducibility... - The elimination of low-dose hyper-radiosensitivity by transfer of irradiated-cell conditioned medium depends on dose rateNina Jeppesen Edin
Department of Physics, The Biophysics Group, University of Oslo, Blindern, Oslo, Norway
Radiat Res 171:22-32. 2009..However, an increase in clonogenic survival was observed in cells receiving only medium transfer without subsequent irradiation that was independent of dose rate... - On the parameter describing the generalised equivalent uniform dose (gEUD) for tumoursAste Søvik
Department of Medical Physics, The Norwegian Radium Hospital, Montebello, Oslo, Norway
Phys Med 23:100-6. 2007..Although the current work shows limitations of the gEUD model for tumours, gEUD may still be preferable for biological treatment plan optimization, evaluation and reporting... - Artificial neural networks for prediction of response to chemoradiation in HT29 xenograftsManish Kakar
Department of Radiation Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway
Int J Radiat Oncol Biol Phys 75:506-11. 2009..To evaluate the feasibility of using neural networks for predicting treatment response by using longitudinal measurements of apparent diffusion coefficient (ADC) obtained from diffusion-weighted magnetic resonance imaging (DWMRI)... - Ultrasound enhanced antitumor activity of liposomal doxorubicin in miceEirik Hagtvet
Department of Radiation Biology, Institute for Cancer Research, Oslo University Hospital and University of Oslo, Oslo, Norway
J Drug Target 19:701-8. 2011..The liposomal DXR formulation alone showed no inhibitory effect on tumor growth. However, upon exposure to low frequency US in situ inhibition of tumor growth was demonstrated... - Iterative reconstruction reduces abdominal CT doseAnne Catrine Trægde Martinsen
The Intervention Centre, Oslo University Hospital, Rikshospitalet, Postboks 4950 Nydalen, N 0424 Oslo, Norway
Eur J Radiol 81:1483-7. 2012.... - Teleradiology with satellite units - six years experience at the norwegian radium hospitalAlbrecht Reith
The Norwegian Radium Hospital, University of Oslo, Oslo, Norway
Stud Health Technol Inform 134:209-16. 2008..Standardization and quality assurance of radiotherapy at the quality level of a comprehensive cancer center can be offered to a much larger population and may play a role in improved cancer survival outcome... - Reconstruction of a ring applicator using CT imaging: impact of the reconstruction method and applicator orientationTaran Paulsen Hellebust
Department of Medical Physics, Rikshospital Radiumhospital Medical Center, Oslo, Norway
Phys Med Biol 52:4893-904. 2007..However, with restrictive guidelines for applicator reconstruction the uncertainties for all methods are low compared to other factors influencing the accuracy of brachytherapy... - Radiobiological responses for two cell lines following continuous low dose-rate (CLDR) and pulsed dose rate (PDR) brachytherapyPer Henrik Hanisch
Department of Medical Physics, The University of Oslo, Oslo, Norway
Acta Oncol 46:602-11. 2007..The underlying cause of this difference is unclear, but cell-cycle parameters, like G2-accumulation is tested and found to be the same for the two cell lines... - Optimization of tumour control probability in hypoxic tumours by radiation dose redistribution: a modelling studyAste Søvik
Department of Medical Physics and Technology, The Norwegian Radium Hospital, and Department of Physics, University of Oslo, 0316 Oslo, Norway
Phys Med Biol 52:499-513. 2007..This could potentially improve treatment outcome in a subpopulation of patients who respond poorly to conventional radiotherapy... - Contralateral breast doses following radiotherapy of the breast and regional lymph nodes: Measurements and treatment planning calculationsSafora Johansen
Department of Radiation Biology, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway
Radiother Oncol 82:332-6. 2007.... - Adapting radiotherapy to hypoxic tumoursEirik Malinen
Department of Radiation Biology, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway
Phys Med Biol 51:4903-21. 2006..In conclusion, improved tumour control of hypoxic tumours by dose redistribution may be expected following hypoxia imaging, tumour control predictions, inverse treatment planning and IMRT... - Electron paramagnetic resonance (EPR) dosimetry using lithium formate in radiotherapy: comparison with thermoluminescence (TL) dosimetry using lithium fluoride rodsTor Arne Vestad
Department of Physics, University of Oslo, P.O. Box 1048, Blindern, N-0316 Oslo, Norway
Phys Med Biol 49:4701-15. 2004.... - Dose painting: art or science?Kari Tanderup
Radiother Oncol 79:245-8. 2006 - Initial evaluation of (227)Th-p-benzyl-DOTA-rituximab for low-dose rate alpha-particle radioimmunotherapyJostein Dahle
Department of Radiation Biology, Rikshospitalet Radiumhospitalet HE, Montebello, 0310 Oslo, Norway
Nucl Med Biol 33:271-9. 2006..4 days. Incubation of lymphoma cells with (227)Th-DOTA-p-benzyl-rituximab resulted in a significant antigen-dependent inhibition of cell growth. The data presented here warrant further studies of (227)Th-DOTA-p-benzyl-rituximab... - Dose optimisation in single plane interstitial brachytherapyKari Tanderup
Department of Oncology, Aarhus University Hospital, Aarhus, Denmark
Radiother Oncol 81:105-11. 2006..Brachytherapy dose distributions can be optimised by modulation of source dwell times. In this study dose optimisation in single planar interstitial implants was evaluated in order to quantify the potential benefit in patients...