P Murphy

Summary

Affiliation: University of Oslo
Country: Norway

Publications

  1. ncbi Expression of the bZIP transcription factor TCF11 and its potential dimerization partners during development
    P Murphy
    Biotechnology Centre of Oslo, University of Oslo, P O Box 1125, Blindern, N 0316, Oslo, Norway
    Mech Dev 97:141-8. 2000
  2. ncbi TCF11/Nrf1 overexpression increases the intracellular glutathione level and can transactivate the gamma-glutamylcysteine synthetase (GCS) heavy subunit promoter
    M C Myhrstad
    Institute for Nutrition Research, University of Oslo, Oslo, Norway
    Biochim Biophys Acta 1517:212-9. 2001
  3. ncbi Two domains of the human bZIP transcription factor TCF11 are necessary for transactivation
    C Husberg
    Biotechnology Centre of Oslo, University of Oslo, Oslo 0316, Norway
    J Biol Chem 276:17641-52. 2001
  4. ncbi Interaction of the CNC-bZIP factor TCF11/LCR-F1/Nrf1 with MafG: binding-site selection and regulation of transcription
    O Johnsen
    Biotechnology Centre of Oslo, University of Oslo, PO Box 1125, Blindern N 0316 Oslo, Norway
    Nucleic Acids Res 26:512-20. 1998
  5. ncbi Expression of the mouse labial-like homeobox-containing genes, Hox 2.9 and Hox 1.6, during segmentation of the hindbrain
    P Murphy
    MRC Human Genetics Unit, Western General Hospital, Edinburgh, UK
    Development 111:61-74. 1991
  6. ncbi The regulation of Krox-20 expression reveals important steps in the control of peripheral glial cell development
    P Murphy
    Unité 368 de l Institut National de la Santé et de la Recherche Médicale, Ecole Normale Superieure, Paris, France
    Development 122:2847-57. 1996
  7. ncbi Several receptor tyrosine kinase genes of the Eph family are segmentally expressed in the developing hindbrain
    N Becker
    Unité INSERM 368, Ecole Normale Superieure, Paris, France
    Mech Dev 47:3-17. 1994
  8. ncbi The heat shock response reduces myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in mice
    M T Heneka
    Department of Neurology, University of Bonn, Bonn, Germany Department of Anesthesiology, University of Illinois, Chicago, Illinois, USA
    J Neurochem 77:568-79. 2001
  9. ncbi Segment-specific expression of a homoeobox-containing gene in the mouse hindbrain
    P Murphy
    MRC Human Genetics Unit, Western General Hospital, Edinburgh, UK
    Nature 341:156-9. 1989
  10. ncbi MSI-H 'medullary type' adenocarcinoma complicating ileal Crohn's disease; further molecular insight into Crohn's-related carcinogenesis
    D S A Sanders
    Histopathology 52:519-23. 2008

Collaborators

  • M A Nieto
  • Douglas Feinstein
  • D S A Sanders
  • C Husberg
  • M C Myhrstad
  • M T Heneka
  • A B Kolsto
  • P Taniere
  • A Yousef
  • F Macdonald
  • R A Carr
  • C McKeown
  • K Glendinning
  • O Johnsen
  • L Dumitrescu
  • E Martin
  • R Blomhoff
  • J A Lyons
  • A Sharp
  • J O Moskaug
  • N Becker
  • H Prydz
  • P Gilardi-Hebenstreit
  • T Seitanidou
  • D G Wilkinson
  • P Charnay
  • M G Mattei
  • P Topilko

Detail Information

Publications10

  1. ncbi Expression of the bZIP transcription factor TCF11 and its potential dimerization partners during development
    P Murphy
    Biotechnology Centre of Oslo, University of Oslo, P O Box 1125, Blindern, N 0316, Oslo, Norway
    Mech Dev 97:141-8. 2000
    ..ATF4 shows evidence of complex regulation during development and shows elevated expression in many of the same sites as TCF11...
  2. ncbi TCF11/Nrf1 overexpression increases the intracellular glutathione level and can transactivate the gamma-glutamylcysteine synthetase (GCS) heavy subunit promoter
    M C Myhrstad
    Institute for Nutrition Research, University of Oslo, Oslo, Norway
    Biochim Biophys Acta 1517:212-9. 2001
    ..We suggest that TCF11/Nrf1 can operate through a subset of AREs to modulate the expression of GCS(h) together with other components of the pathway and in this way play a role in regulating cellular glutathione levels...
  3. ncbi Two domains of the human bZIP transcription factor TCF11 are necessary for transactivation
    C Husberg
    Biotechnology Centre of Oslo, University of Oslo, Oslo 0316, Norway
    J Biol Chem 276:17641-52. 2001
    ..The resulting profile of activity is most likely achieved by interaction of the domains and their cell-specific environment...
  4. ncbi Interaction of the CNC-bZIP factor TCF11/LCR-F1/Nrf1 with MafG: binding-site selection and regulation of transcription
    O Johnsen
    Biotechnology Centre of Oslo, University of Oslo, PO Box 1125, Blindern N 0316 Oslo, Norway
    Nucleic Acids Res 26:512-20. 1998
    ..Efficient positive regulation by TCF11 may require alternative partners with perhaps more restricted expression patterns...
  5. ncbi Expression of the mouse labial-like homeobox-containing genes, Hox 2.9 and Hox 1.6, during segmentation of the hindbrain
    P Murphy
    MRC Human Genetics Unit, Western General Hospital, Edinburgh, UK
    Development 111:61-74. 1991
    ..4) Hox 2.9 expression is confined to the region of rhombomere 4 that shows cell lineage restriction and, unlike Krox 20, is expressed throughout the period that rhombomeres are visible (to 11 1/2 days).(ABSTRACT TRUNCATED AT 400 WORDS)..
  6. ncbi The regulation of Krox-20 expression reveals important steps in the control of peripheral glial cell development
    P Murphy
    Unité 368 de l Institut National de la Santé et de la Recherche Médicale, Ecole Normale Superieure, Paris, France
    Development 122:2847-57. 1996
    ..iii) In sensory ganglia, the microenvironment is capable of negatively regulating Krox-20, presumably by preventing the conversion of satellite glial cells toward a Schwann cell-like phenotype...
  7. ncbi Several receptor tyrosine kinase genes of the Eph family are segmentally expressed in the developing hindbrain
    N Becker
    Unité INSERM 368, Ecole Normale Superieure, Paris, France
    Mech Dev 47:3-17. 1994
    ..1992; Nieto et al., 1992), these data indicate that members of the Eph family of RTKs may co-operate in the segmental patterning of the hindbrain...
  8. ncbi The heat shock response reduces myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in mice
    M T Heneka
    Department of Neurology, University of Bonn, Bonn, Germany Department of Anesthesiology, University of Illinois, Chicago, Illinois, USA
    J Neurochem 77:568-79. 2001
    ..The finding that the SR reduces inflammation in the brain and the clinical severity of EAE opens a novel therapeutic approach for prevention of autoimmune diseases...
  9. ncbi Segment-specific expression of a homoeobox-containing gene in the mouse hindbrain
    P Murphy
    MRC Human Genetics Unit, Western General Hospital, Edinburgh, UK
    Nature 341:156-9. 1989
    ..9, is expressed in a segment-specific manner in the developing mouse hindbrain. This expression is in a region which is flanked by the regions of expression of Krox-20, and is precisely contained within a single neuromere, rhombomere 4...
  10. ncbi MSI-H 'medullary type' adenocarcinoma complicating ileal Crohn's disease; further molecular insight into Crohn's-related carcinogenesis
    D S A Sanders
    Histopathology 52:519-23. 2008