O Molberg

Summary

Affiliation: University of Oslo
Country: Norway

Publications

  1. ncbi request reprint T cells from celiac disease lesions recognize gliadin epitopes deamidated in situ by endogenous tissue transglutaminase
    O Molberg
    Institute of Immunology, Rikshospitalet, University of Oslo, Norway
    Eur J Immunol 31:1317-23. 2001
  2. ncbi request reprint Intestinal T-cell responses to high-molecular-weight glutenins in celiac disease
    Øyvind Molberg
    Institute of Immunology, Rikshospitalet, University of Oslo, N 0027, Oslo, Norway
    Gastroenterology 125:337-44. 2003
  3. ncbi request reprint Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease
    O Molberg
    Institute of Transplantation Immunology, Rikshospitalet, University of Oslo, Norway
    Nat Med 4:713-7. 1998
  4. ncbi request reprint HLA binding and T cell recognition of a tissue transglutaminase-modified gliadin epitope
    H Quarsten
    Institute of Immunology, Rikshospitalet, University of Oslo, Oslo, Norway
    Eur J Immunol 29:2506-14. 1999
  5. ncbi request reprint Genes and environment in celiac disease
    L M Sollid
    Institute of Immunology and Medical Department, Rikshospitalet, University of Oslo, Norway
    Acta Odontol Scand 59:183-6. 2001
  6. ncbi request reprint CD4+ T cells with specific reactivity against astrovirus isolated from normal human small intestine
    O Molberg
    Institute of Transplantation Immunology, Rikshospitalet, Oslo, Norway
    Gastroenterology 114:115-22. 1998
  7. pmc The effects of atorvastatin on gluten-induced intestinal T cell responses in coeliac disease
    M Raki
    Institute of Immunology, University of Oslo, Rikshospitalet University Hospital, Norway
    Clin Exp Immunol 142:333-40. 2005
  8. pmc Production of a panel of recombinant gliadins for the characterisation of T cell reactivity in coeliac disease
    E H Arentz-Hansen
    Institute of Immunology, Rikshospitalet, University of Oslo, Norway
    Gut 46:46-51. 2000
  9. doi request reprint Interleukin-15 induces interleukin-17 production by synovial T cell lines from patients with rheumatoid arthritis
    E H Halvorsen
    Centre for Immune Regulation, Institute of Immunology, University of Oslo and Oslo University Hospital, Oslo, Norway
    Scand J Immunol 73:243-9. 2011

Collaborators

Detail Information

Publications9

  1. ncbi request reprint T cells from celiac disease lesions recognize gliadin epitopes deamidated in situ by endogenous tissue transglutaminase
    O Molberg
    Institute of Immunology, Rikshospitalet, University of Oslo, Norway
    Eur J Immunol 31:1317-23. 2001
    ..These data demonstrate that DQ2-restricted T cells within adult celiac lesions predominantly recognize deamidated gliadin epitopes that are formed in situ by endogenous tTG...
  2. ncbi request reprint Intestinal T-cell responses to high-molecular-weight glutenins in celiac disease
    Øyvind Molberg
    Institute of Immunology, Rikshospitalet, University of Oslo, N 0027, Oslo, Norway
    Gastroenterology 125:337-44. 2003
    ....
  3. ncbi request reprint Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease
    O Molberg
    Institute of Transplantation Immunology, Rikshospitalet, University of Oslo, Norway
    Nat Med 4:713-7. 1998
    ..Generation of epitopes by enzymatic modification is a new mechanism that may be relevant for breaking of tolerance and initiation of autoimmune disease...
  4. ncbi request reprint HLA binding and T cell recognition of a tissue transglutaminase-modified gliadin epitope
    H Quarsten
    Institute of Immunology, Rikshospitalet, University of Oslo, Oslo, Norway
    Eur J Immunol 29:2506-14. 1999
    ..This provides additional evidence that tTG is responsible for modification of gliadin in vivo...
  5. ncbi request reprint Genes and environment in celiac disease
    L M Sollid
    Institute of Immunology and Medical Department, Rikshospitalet, University of Oslo, Norway
    Acta Odontol Scand 59:183-6. 2001
    ..The minor genetic effects of the non-HLA genes could indicate a lack of critical checkpoints along these pathways, or that there are several pathways leading to the lesion formation...
  6. ncbi request reprint CD4+ T cells with specific reactivity against astrovirus isolated from normal human small intestine
    O Molberg
    Institute of Transplantation Immunology, Rikshospitalet, Oslo, Norway
    Gastroenterology 114:115-22. 1998
    ..Serum antibodies against astrovirus are prevalent, indicating frequent viral exposure and postinfectious induction of systemic immune responses. Mucosal immune responses may conceivably mediate protection on astroviral reinfections...
  7. pmc The effects of atorvastatin on gluten-induced intestinal T cell responses in coeliac disease
    M Raki
    Institute of Immunology, University of Oslo, Rikshospitalet University Hospital, Norway
    Clin Exp Immunol 142:333-40. 2005
    ..In conclusion, atorvastatin has specific effects on isolated gluten-reactive T cells and dendritic cells, but does not shut down the gluten-induced production of proinflammatory cytokines in intestinal biopsies...
  8. pmc Production of a panel of recombinant gliadins for the characterisation of T cell reactivity in coeliac disease
    E H Arentz-Hansen
    Institute of Immunology, Rikshospitalet, University of Oslo, Norway
    Gut 46:46-51. 2000
    ..To aid the characterisation of gliadin T cell epitopes, multiple recombinant gliadins have been produced from a commercial Nordic wheat cultivar...
  9. doi request reprint Interleukin-15 induces interleukin-17 production by synovial T cell lines from patients with rheumatoid arthritis
    E H Halvorsen
    Centre for Immune Regulation, Institute of Immunology, University of Oslo and Oslo University Hospital, Oslo, Norway
    Scand J Immunol 73:243-9. 2011
    ..The Th17 cells from the RA ST were enriched in the CD4+ CCR6+ population, and they were sensitive to exogenous IL-15. Th17 cells present within the synovial compartment may contribute to the RA pathogenesis and local joint damage...