Ingrid Melle

Summary

Affiliation: University of Oslo
Country: Norway

Publications

  1. pmc Neurocognitive features in subgroups of bipolar disorder
    Sofie Ragnhild Aminoff
    KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Ullevaal Hospital, Oslo, Norway
    Bipolar Disord 15:272-83. 2013
  2. pmc Association between a genetic variant in the serotonin transporter gene (SLC6A4) and suicidal behavior in patients with schizophrenia
    Eva Lindholm Carlström
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, Stockholm, Sweden
    Behav Brain Funct 8:24. 2012
  3. pmc Patterns of childhood adverse events are associated with clinical characteristics of bipolar disorder
    Sara Larsson
    Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    BMC Psychiatry 13:97. 2013
  4. pmc Therapeutic alliance in early schizophrenia spectrum disorders: a cross-sectional study
    Ragnhild Johansen
    Forensic Department Brøset, Centre for Research and Education in Forensic Psychiatry, St, Olav s Hospital, Trondheim University Hospital, P, Box 3008 Lade, Trondheim, 7441, Norway
    Ann Gen Psychiatry 12:14. 2013
  5. doi request reprint Insight and suicidal behavior in first-episode schizophrenia
    Ingrid Melle
    Division of Mental Health and Addiction, Building 49, Oslo University Hospital Ulleval, PO Box 4956, Nydalen, 0424 Oslo, Norway
    Expert Rev Neurother 12:353-9. 2012
  6. pmc Previous hospital admissions and disease severity predict the use of antipsychotic combination treatment in patients with schizophrenia
    Albert Bolstad
    Department of Psychiatry Research, Diakonhjemmet Hospital, P O Box 85 Vinderen, Oslo 0319, Norway
    BMC Psychiatry 11:126. 2011
  7. pmc The estrogen hypothesis of schizophrenia implicates glucose metabolism: association study in three independent samples
    Line Olsen
    Research Institute of Biological Psychiatry, Sct, Hans Hospital, DK 4000 Roskilde, Denmark
    BMC Med Genet 9:39. 2008
  8. ncbi request reprint Prevention of negative symptom psychopathologies in first-episode schizophrenia: two-year effects of reducing the duration of untreated psychosis
    Ingrid Melle
    Section for Psychosis Research, Division of Psychiatry, Ulleval University Hospital, 0407 Oslo, Norway
    Arch Gen Psychiatry 65:634-40. 2008
  9. ncbi request reprint Course and predictors of suicidality over the first two years of treatment in first-episode schizophrenia spectrum psychosis
    Ingrid Melle
    Clinic for Mental Health and Addiction, Department of Psychiatry, University of Oslo, Oslo University Hospital, Kirkeveien 166, Oslo, Norway
    Arch Suicide Res 14:158-70. 2010
  10. ncbi request reprint Measuring quality of life in first-episode psychosis
    I Melle
    Department of Research and Education, Division of Psychiatry, Ulleval University Hospital, 0407 Oslo, Norway
    Eur Psychiatry 20:474-83. 2005

Detail Information

Publications124 found, 100 shown here

  1. pmc Neurocognitive features in subgroups of bipolar disorder
    Sofie Ragnhild Aminoff
    KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Ullevaal Hospital, Oslo, Norway
    Bipolar Disord 15:272-83. 2013
    ..To examine which subgroups of DSM-IV bipolar disorder (BD) [BD type I (BD-I) or BD type II (BD-II), and subgroups based on history of psychosis, presenting polarity, and age at onset] differentiate best regarding neurocognitive measures...
  2. pmc Association between a genetic variant in the serotonin transporter gene (SLC6A4) and suicidal behavior in patients with schizophrenia
    Eva Lindholm Carlström
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, Stockholm, Sweden
    Behav Brain Funct 8:24. 2012
    ..In this study, we wanted to elucidate whether SLC6A4 variations is involved in attempted suicide among patients with schizophrenia in a Scandinavian case-control sample...
  3. pmc Patterns of childhood adverse events are associated with clinical characteristics of bipolar disorder
    Sara Larsson
    Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    BMC Psychiatry 13:97. 2013
    ....
  4. pmc Therapeutic alliance in early schizophrenia spectrum disorders: a cross-sectional study
    Ragnhild Johansen
    Forensic Department Brøset, Centre for Research and Education in Forensic Psychiatry, St, Olav s Hospital, Trondheim University Hospital, P, Box 3008 Lade, Trondheim, 7441, Norway
    Ann Gen Psychiatry 12:14. 2013
    ..This study explores predictors and characteristics of the therapeutic alliance in recent-onset schizophrenia spectrum disorders including the agreement between patient and therapist alliance ratings...
  5. doi request reprint Insight and suicidal behavior in first-episode schizophrenia
    Ingrid Melle
    Division of Mental Health and Addiction, Building 49, Oslo University Hospital Ulleval, PO Box 4956, Nydalen, 0424 Oslo, Norway
    Expert Rev Neurother 12:353-9. 2012
    ..In this article, we will present a review of studies illustrating the complex background of suicide risk in schizophrenia, with a particular emphasis on the role of insight in the early phases of schizophrenia...
  6. pmc Previous hospital admissions and disease severity predict the use of antipsychotic combination treatment in patients with schizophrenia
    Albert Bolstad
    Department of Psychiatry Research, Diakonhjemmet Hospital, P O Box 85 Vinderen, Oslo 0319, Norway
    BMC Psychiatry 11:126. 2011
    ....
  7. pmc The estrogen hypothesis of schizophrenia implicates glucose metabolism: association study in three independent samples
    Line Olsen
    Research Institute of Biological Psychiatry, Sct, Hans Hospital, DK 4000 Roskilde, Denmark
    BMC Med Genet 9:39. 2008
    ..Thus, we tested the hypothesis that variants of the glycolytic genes are associated with schizophrenia or at least with gender-associated aspects of the illness...
  8. ncbi request reprint Prevention of negative symptom psychopathologies in first-episode schizophrenia: two-year effects of reducing the duration of untreated psychosis
    Ingrid Melle
    Section for Psychosis Research, Division of Psychiatry, Ulleval University Hospital, 0407 Oslo, Norway
    Arch Gen Psychiatry 65:634-40. 2008
    ..The duration of untreated psychosis (DUP)-the time from onset of psychotic symptoms to the start of adequate treatment--is consistently correlated with better course and outcome, but the mechanisms are poorly understood...
  9. ncbi request reprint Course and predictors of suicidality over the first two years of treatment in first-episode schizophrenia spectrum psychosis
    Ingrid Melle
    Clinic for Mental Health and Addiction, Department of Psychiatry, University of Oslo, Oslo University Hospital, Kirkeveien 166, Oslo, Norway
    Arch Suicide Res 14:158-70. 2010
    ..Severe suicidality (plans and attempts) was predicted by drug abuse, dissatisfaction with life and severe suicidality at start of treatment...
  10. ncbi request reprint Measuring quality of life in first-episode psychosis
    I Melle
    Department of Research and Education, Division of Psychiatry, Ulleval University Hospital, 0407 Oslo, Norway
    Eur Psychiatry 20:474-83. 2005
    ....
  11. ncbi request reprint Early detection of the first episode of schizophrenia and suicidal behavior
    Ingrid Melle
    Department of Research and Education, Division of Psychiatry, Ulleval University Hospital, N 0407 Oslo, Norway
    Am J Psychiatry 163:800-4. 2006
    ..Treatment programs that bring first-episode patients into treatment at lower symptom levels can have the potential to reduce risk for suicide attempts...
  12. doi request reprint The development of subjective quality of life over the first 2 years in first-episode psychosis
    Ingrid Melle
    Department of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    J Nerv Ment Dis 198:864-9. 2010
    ..Improvements in general s-QoL were associated with increase in excitative symptoms and with improvements in depressive symptoms, global functioning, level of daily activities, level of social activities, and perceived general health...
  13. doi request reprint Subcortical brain volumes relate to neurocognition in schizophrenia and bipolar disorder and healthy controls
    Cecilie B Hartberg
    Institute of Clinical Medicine, Psychiatry Section, University of Oslo, Norway
    Prog Neuropsychopharmacol Biol Psychiatry 35:1122-30. 2011
    ..It is unknown whether relationships between subcortical volumes and neurocognitive performance are similar or different between schizophrenia and bipolar disorder...
  14. ncbi request reprint Depression and depressive symptoms in first episode psychosis
    Kristin Lie Romm
    Department of Psychiatry, Oslo University Hospital, Ulleval, Oslo, Norway
    J Nerv Ment Dis 198:67-71. 2010
    ..Thus depressive symptoms are frequent among FEPP, with indications of gender specific differences in patient characteristics that might imply different approaches to treatment...
  15. doi request reprint Sex-specific cortisol levels in bipolar disorder and schizophrenia during mental challenge--relationship to clinical characteristics and medication
    Nils Eiel Steen
    Psychosis Research Unit, Division of Mental Health and Addiction, Oslo University Hospital, Ulleval Hospital, P O Box 4956 Nydalen, 0424 Oslo, Norway
    Prog Neuropsychopharmacol Biol Psychiatry 35:1100-7. 2011
    ....
  16. ncbi request reprint Suicidality before and in the early phases of first episode psychosis
    Elizabeth A Barrett
    Department of Mental Health, Oslo University Hospital, 0514 Oslo, Norway
    Schizophr Res 119:11-7. 2010
    ..This study explored the prevalence and characteristics of suicidality in patients with a first episode of psychosis (FEP) in two time intervals: 1) prior to study entry and 2) explicitly in the period of untreated psychosis...
  17. doi request reprint Cannabis use and premorbid functioning as predictors of poorer neurocognition in schizophrenia spectrum disorder
    P Andreas Ringen
    KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital, N 0424 Oslo, Norway
    Schizophr Res 143:84-9. 2013
    ..We investigated the relation between cannabis use, determined by its presence in urine, and neurocognitive functioning in schizophrenia controlling for the potential bias of premorbid functioning...
  18. doi request reprint Suicidality in first episode psychosis is associated with insight and negative beliefs about psychosis
    Elizabeth A Barrett
    Department of Mental Health and Addiction, Oslo University Hospital, 0424 Oslo, Norway
    Schizophr Res 123:257-62. 2010
    ....
  19. ncbi request reprint Cardiovascular risk factors during second generation antipsychotic treatment are associated with increased C-reactive protein
    Ingrid Dieset
    Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    Schizophr Res 140:169-74. 2012
    ..We investigated whether there is a relationship between CVD risk factors and inflammation in schizophrenia or bipolar disorder, and if second generation antipsychotics (SGA) interact...
  20. pmc Apathy, poor verbal memory and male gender predict lower psychosocial functioning one year after the first treatment of psychosis
    Ann Faerden
    Oslo University Hospital, Ulleval, 0407 Oslo, Norway Electronic address
    Psychiatry Res 210:55-61. 2013
    ..Apathy is a negative symptom associated with poor psychosocial functioning in schizophrenia but has not been sufficiently studied as predictor of poor functioning in first episode psychosis (FEP)...
  21. ncbi request reprint Catechol O-methyltransferase variants and cognitive performance in schizophrenia and bipolar disorder versus controls
    Katrine V Wirgenes
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Schizophr Res 122:31-7. 2010
    ..However, the results have been inconsistent and there are few studies addressing other COMT single nucleotide polymorphisms (SNPs)...
  22. doi request reprint Neurocognitive development in first episode psychosis 5 years follow-up: associations between illness severity and cognitive course
    Helene Eidsmo Barder
    Division of Mental Health and Addiction, Oslo University Hospital, N 0407 Oslo, Norway
    Schizophr Res 149:63-9. 2013
    ....
  23. doi request reprint ZNF804A and cortical thickness in schizophrenia and bipolar disorder
    Orjan Bergmann
    KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    Psychiatry Res 212:154-7. 2013
    ..Results show no significant associations...
  24. doi request reprint Factors associated with occupational and academic status in patients with first-episode psychosis with a particular focus on neurocognition
    Marte Tandberg
    Division of Mental Health and Addiction, Oslo University Hospital, 0407 Oslo, Norway
    Soc Psychiatry Psychiatr Epidemiol 47:1763-73. 2012
    ..Further, it investigated the relationship between students, employed and unemployed patients and clinical, neurocognitive, global, and social functioning...
  25. doi request reprint Apathy in first episode psychosis patients: a ten year longitudinal follow-up study
    Julie Evensen
    Division of Mental Health and Addiction, Oslo University Hospital, N 0407, Oslo, Norway
    Schizophr Res 136:19-24. 2012
    ..Apathy is a common symptom in first episode psychosis (FEP), and is associated with poor functioning. Prevalence and correlates of apathy 10 years after the first psychotic episode remain unexplored...
  26. doi request reprint Association analysis of ANK3 gene variants in nordic bipolar disorder and schizophrenia case-control samples
    Martin Tesli
    Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 156:969-74. 2011
    ..These results further support that ANK3 is a susceptibility gene specific to BD and that more than one risk locus is involved...
  27. doi request reprint Association study of PDE4B gene variants in Scandinavian schizophrenia and bipolar disorder multicenter case-control samples
    Anna K Kähler
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 153:86-96. 2010
    ..Further studies are needed to evaluate the implicated PDE4B region of interest, for potential involvement in SZ and BP susceptibility...
  28. doi request reprint Neurocognitive functioning and suicidality in schizophrenia spectrum disorders
    Elizabeth A Barrett
    Department of Mental Health and Addiction, Oslo University Hospital, 0424 Oslo, Norway
    Compr Psychiatry 52:156-63. 2011
    ....
  29. doi request reprint Dysbindin and d-amino-acid-oxidase gene polymorphisms associated with positive and negative symptoms in schizophrenia
    Katrine V Wirgenes
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Neuropsychobiology 60:31-6. 2009
    ....
  30. pmc Neurocognitive dysfunction in bipolar and schizophrenia spectrum disorders depends on history of psychosis rather than diagnostic group
    Carmen Simonsen
    Department of Psychology, University of Oslo, 0317 Oslo, Norway
    Schizophr Bull 37:73-83. 2011
    ..We asked whether neurocognitive dysfunction in bipolar and schizophrenia spectrum disorders depends more on history of psychosis than diagnostic category or subtype...
  31. doi request reprint Sex differences in neuropsychological performance and social functioning in schizophrenia and bipolar disorder
    Anja Vaskinn
    Oslo University Hospital, Psychosis Research Unit, Oslo, Norway
    Neuropsychology 25:499-510. 2011
    ..To investigate sex differences in neurocognition and social functioning in schizophrenia and bipolar disorder and the possible role of sex as a moderator of this relationship...
  32. doi request reprint Neurocognition and occupational functioning in patients with first-episode psychosis: a 2-year follow-up study
    Marte Tandberg
    Division of Mental Health and Addiction, Oslo University Hospital, 0407 Oslo, Norway
    Psychiatry Res 188:334-42. 2011
    ..For those unemployed at baseline, none of the variables predicted change in employment status. Implications of these results are discussed...
  33. ncbi request reprint Neurocognitive dysfunction in first-episode psychosis: correlates with symptoms, premorbid adjustment, and duration of untreated psychosis
    Bjørn Rishovd Rund
    Department of Psychiatry, Ulleval University Hospital, Oslo, Norway
    Am J Psychiatry 161:466-72. 2004
    ....
  34. doi request reprint BDNF val66met modulates the association between childhood trauma, cognitive and brain abnormalities in psychoses
    Monica Aas
    Institute of Clinical Medicine, University of Oslo, Norway Psychosis Research Unit, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway Electronic address
    Prog Neuropsychopharmacol Biol Psychiatry 46:181-8. 2013
    ....
  35. ncbi request reprint The course of neurocognitive functioning in first-episode psychosis and its relation to premorbid adjustment, duration of untreated psychosis, and relapse
    Bjørn Rishovd Rund
    Department of Psychology, University of Oslo, P O Box 1094 Blindern, N 0317 Oslo, Norway
    Schizophr Res 91:132-40. 2007
    ..More severe deficits in WM and VL are associated with more relapses during the first year. It is unclear whether NP deficits cause relapse, relapse causes NP deficits, or both are manifestations of a third deteriorative process...
  36. doi request reprint A comparison of adolescent- and adult-onset first-episode, non-affective psychosis: 2-year follow-up
    Johannes Langeveld
    Department of Psychiatry, Regional Centre for Clinical Research in Psychosis, Stavanger University Hospital, Norway
    Eur Arch Psychiatry Clin Neurosci 262:599-605. 2012
    ..Our results indicate that adolescent-onset and adult-onset psychosis have similar prognostic trajectories, although both may predict a qualitatively different course from childhood-onset psychosis...
  37. doi request reprint Flat affect and social functioning: a 10 year follow-up study of first episode psychosis patients
    Julie Evensen
    Division of Mental Health and Addiction, Oslo University Hospital, N 0407, Oslo, Norway
    Schizophr Res 139:99-104. 2012
    ..Affective flattening has been described as enduring, but long term follow-up studies of first episode psychosis patients are lacking...
  38. doi request reprint Genome-wide association study identifies genetic loci associated with body mass index and high density lipoprotein-cholesterol levels during psychopharmacological treatment - a cross-sectional naturalistic study
    Lavinia Athanasiu
    Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    Psychiatry Res 197:327-36. 2012
    ..This deserves to be replicated in additional populations to provide more evidence for molecular genetic mechanisms of side effects during psychopharmacological treatment...
  39. doi request reprint Neurocognitive functioning in patients recently diagnosed with bipolar disorder
    Tone Hellvin
    Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    Bipolar Disord 14:227-38. 2012
    ..In this study we compare neurocognitive function in a cohort of first-contact mania patients with a healthy control group matched for age, gender, and education...
  40. doi request reprint Affective symptoms are associated with markers of inflammation and immune activation in bipolar disorders but not in schizophrenia
    Sigrun Hope
    Department of Psychiatry, Østfold Hospital, Fredrikstad, Norway
    J Psychiatr Res 45:1608-16. 2011
    ..We aimed to determine if immune markers that consistently have been reported elevated in BP were associated with depressive and manic symptoms, and if this was specific for BP...
  41. doi request reprint Psychosocial function in schizophrenia and bipolar disorder: Relationship to neurocognition and clinical symptoms
    Carmen Simonsen
    Psychosis Research Section, Oslo University Hospital, Oslo, Norway
    J Int Neuropsychol Soc 16:771-83. 2010
    ..Despite differences in neurocognition and psychosocial function, groups showed the same pattern in prediction of functioning irrespective of DSM-IV or clinical definition...
  42. ncbi request reprint A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample
    Srdjan Djurovic
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    J Affect Disord 126:312-6. 2010
    ..In the present study we investigated genetic variants associated with bipolar disorder in a homogenous Norwegian sample, and potential genetic overlap with schizophrenia, using the Affymetrix 6.0 array...
  43. doi request reprint Apathy in first episode psychosis patients: one year follow up
    Ann Faerden
    Oslo University Hospital, Ulleval, 0407 Oslo, Norway
    Schizophr Res 116:20-6. 2010
    ....
  44. pmc Clinical characteristics in schizophrenia patients with or without suicide attempts and non-suicidal self-harm--a cross-sectional study
    Erlend Mork
    National Centre for Suicide Research and Prevention, Institute of Clinical Medicine, University of Oslo, Sognsvannsveien 21, 0372 Oslo, Norway
    BMC Psychiatry 13:255. 2013
    ....
  45. doi request reprint Occupational outcome in bipolar disorder is not predicted by premorbid functioning and intelligence
    Helle K Schoeyen
    Moodnet Research Group, Division of Psychiatry, Stavanger University Hospital, Stavanger, Norway
    Bipolar Disord 15:294-305. 2013
    ..The present study addressed the role of premorbid functioning [assessed with the Premorbid Adjustment Scale (PAS)], intelligence, course of illness, and sociodemographics on occupational outcome in BD...
  46. doi request reprint Early detection, early symptom progression and symptomatic remission after ten years in a first episode of psychosis study
    Wenche Ten Velden Hegelstad
    Regional Centre for Clinical Research in Psychosis, Division of Psychiatry, Stavanger University Hospital, Norway, PO Box 8100, 4068 Stavanger, Norway
    Schizophr Res 143:337-43. 2013
    ..Poor symptom outcome remains a challenge in psychosis: At least 50% of first-episode patients continue to have positive and/or negative symptoms after ten years...
  47. pmc CACNA1C risk variant and amygdala activity in bipolar disorder, schizophrenia and healthy controls
    Martin Tesli
    Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    PLoS ONE 8:e56970. 2013
    ....
  48. doi request reprint Is cognitive impairment following early life stress in severe mental disorders based on specific or general cognitive functioning?
    Monica Aas
    Institute of Clinical Medicine, University of Oslo, Norway
    Psychiatry Res 198:495-500. 2012
    ..Moreover, these dysfunctions seem to be driven by underlying deficits in general cognitive tasks as measured by the WASI...
  49. doi request reprint Severe social anxiety in early psychosis is associated with poor premorbid functioning, depression, and reduced quality of life
    Kristin Lie Romm
    Psychosis Research Unit, Division of Mental Health and Addiction, Oslo University Hospital, 0407 Oslo, Norway
    Compr Psychiatry 53:434-40. 2012
    ..Furthermore, we wanted to explore whether social anxiety is associated with reduced quality of life (QoL)...
  50. ncbi request reprint Treatment delay and excessive substance use in bipolar disorder
    Trine Vik Lagerberg
    Psychosis Research Unit, Division of Mental Health and Addiction, Department of Research and Development, Oslo University Hospital, Oslo, Norway
    J Nerv Ment Dis 198:628-33. 2010
    ..Patients with antecedent excessive substance use had reduced risk of long treatment delays. The risk of developing excessive substance use after BD onset increased with longer treatment delays...
  51. doi request reprint Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area
    Anna K Kähler
    Institute of Psychiatry, University of Oslo, Oslo University Hospital Ulleval, Norway
    Biol Psychiatry 69:90-6. 2011
    ..Extracellular matrix structures called perineuronal nets, condensed around subsets of neurons and proximal dendrites during brain maturation, regulate synaptic transmission and plasticity...
  52. ncbi request reprint Pathways to care for first-episode psychosis in an early detection healthcare sector: part of the Scandinavian TIPS study
    Jan Olav Johannessen
    Division of Psychiatry, General Hospital of Rogaland, Armauer Hanssens vei 20, 4000 Stavanger, Norway
    Br J Psychiatry Suppl 48:s24-8. 2005
    ..Early detection programmes aim to reduce the duration of untreated psychosis (DUP) by public education and by prompt access to treatment via active outreach detection teams...
  53. ncbi request reprint Apathy and functioning in first-episode psychosis
    Ann Faerden
    Department of Psychiatry, Ulleval University Hospital, Oslo, Norway
    Psychiatr Serv 60:1495-503. 2009
    ....
  54. doi request reprint Social cognition and clinical insight in schizophrenia and bipolar disorder
    Anja Vaskinn
    KG Jebsen Centre for Psychosis Research, Oslo University Hospital, Oslo, Norway
    J Nerv Ment Dis 201:445-51. 2013
    ..Poorer insight was associated with higher symptom load. Social cognition seems to be of importance for clinical insight in schizophrenia, whereas symptoms are important in bipolar I disorder...
  55. doi request reprint High prevalence of childhood trauma in patients with schizophrenia spectrum and affective disorder
    Sara Larsson
    Department of Research and Development, Clinic of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    Compr Psychiatry 54:123-7. 2013
    ....
  56. doi request reprint Effect of DISC1 SNPs on brain structure in healthy controls and patients with a history of psychosis
    Anna K Kähler
    Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 159:722-30. 2012
    ..In conclusion, DISC1 SNPs might impact brain structural variation, possibly differently in psychosis patients versus controls, but independent replication will be needed to confirm our findings...
  57. doi request reprint Object relations and reality testing in schizophrenia, bipolar disorders, and healthy controls: differences in profiles and clinical correlates
    Charlotte Fredslund Hansen
    Department of Psychology, University of Oslo, Norway
    Compr Psychiatry 53:1200-7. 2012
    ..In the current study, we examine if there are OR and RT differences in schizophrenia and bipolar disorder compared to healthy controls and to what extent differences in clinical characteristics mediates the putative effect of diagnosis...
  58. ncbi request reprint Object relations, reality testing, and social withdrawal in schizophrenia and bipolar disorder
    Charlotte Fredslund Hansen
    Department of Psychology, University of Oslo, Oslo, Norway
    J Nerv Ment Dis 201:222-5. 2013
    ..These two measures, together with the level of alienation, explained a significant amount of variance in self-experienced social dysfunction. Findings reveal the multidimensional nature of social dysfunction in severe mental disorders...
  59. doi request reprint Up-regulation of NOTCH4 gene expression in bipolar disorder
    Ingrid Dieset
    Division of Mental Health and Addiction, Oslo University Hospital Ulleval, Oslo, Norway
    Am J Psychiatry 169:1292-300. 2012
    ..The authors investigated the NOTCH4 gene expression in individuals with bipolar disorder and schizophrenia relative to healthy comparison subjects and identified putative expression quantitative trait loci in and around the NOTCH4 gene...
  60. ncbi request reprint Genome-wide study identifies PTPRO and WDR72 and FOXQ1-SUMO1P1 interaction associated with neurocognitive function
    Marissa Leblanc
    Epi Gen, Institute of Clinical Medicine, Akershus University Hospital, University of Oslo, Oslo, Norway
    J Psychiatr Res 46:271-8. 2012
    ..We performed a genome-wide association study (GWAS) to identify genes associated with neurocognition...
  61. doi request reprint Cortical volume, surface area, and thickness in schizophrenia and bipolar disorder
    Lars M Rimol
    Division of Mental Health and Addiction, Institute of Clinical Medicine, University of Oslo, Norway
    Biol Psychiatry 71:552-60. 2012
    ....
  62. pmc Serotonin transporter gene polymorphism, childhood trauma, and cognition in patients with psychotic disorders
    Monica Aas
    Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    Schizophr Bull 38:15-22. 2012
    ..We hypothesize that 5-HTTLPR variations and long-term effects of childhood trauma interact and contribute to some of the variation in cognitive dysfunction seen in patients with psychotic disorders...
  63. ncbi request reprint Reducing the duration of untreated first-episode psychosis: effects on clinical presentation
    Ingrid Melle
    Division of Psychiatry, Ullevaal University Hospital, Oslo, Norway
    Arch Gen Psychiatry 61:143-50. 2004
    ..Most studies on first-episode psychosis show an association between a long duration of untreated psychosis (DUP) and poorer short-term outcome, but the mechanisms of this relationship are poorly understood...
  64. pmc Excessive cannabis use is associated with earlier age at onset in bipolar disorder
    Trine V Lagerberg
    Department of Research and Development, Division of Mental Health and Addiction, Oslo University Hospital, Norway
    Eur Arch Psychiatry Clin Neurosci 261:397-405. 2011
    ..This indicates that an early onset may increase the risk of cannabis use and that cannabis use may trigger bipolar disorder in vulnerable individuals...
  65. doi request reprint Intron 12 in NTRK3 is associated with bipolar disorder
    Lavinia Athanasiu
    Department of Psychiatry, Oslo University Hospital Ulleval, Oslo, Norway
    Psychiatry Res 185:358-62. 2011
    ....
  66. pmc Perceived discrimination is associated with severity of positive and depression/anxiety symptoms in immigrants with psychosis: a cross-sectional study
    Akiah O Berg
    Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway
    BMC Psychiatry 11:77. 2011
    ..We investigated if perceived discrimination was associated with the severity of these symptoms among immigrants in Norway with psychotic disorders...
  67. doi request reprint Increased systemic cortisol metabolism in patients with schizophrenia and bipolar disorder: a mechanism for increased stress vulnerability?
    Nils Eiel Steen
    Section for Psychosis Research, Clinic of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    J Clin Psychiatry 72:1515-21. 2011
    ....
  68. pmc Contrasting monosymptomatic patients with hallucinations and delusions in first-episode psychosis patients: a five-year longitudinal follow-up study
    Julie Evensen
    Division of Psychiatry, Oslo University Hospital, Oslo, Norway
    Psychopathology 44:90-7. 2011
    ....
  69. doi request reprint Association analysis of PALB2 and BRCA2 in bipolar disorder and schizophrenia in a scandinavian case-control sample
    Martin Tesli
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 153:1276-82. 2010
    ..Our findings support PALB2 and BRCA2 as risk genes specifically for BD, and suggest that altered DNA repair related to neurogenesis may be involved in BD pathophysiology. © 2010 Wiley-Liss, Inc...
  70. doi request reprint The use of screening instruments for detecting alcohol and other drug use disorders in first-episode psychosis
    Ragnar Nesvåg
    Department of Psychiatry, Diakonhjemmet Hospital, Oslo, Norway
    Psychiatry Res 177:228-34. 2010
    ..The results of this study suggest that AUDIT and DUDIT are powerful screening instruments for detecting alcohol and other drug use disorders in patients with first-episode psychosis...
  71. pmc Osteoprotegerin levels in patients with severe mental disorders
    Sigrun Hope
    Department of Psychiatry, Østfold Hospital, Fredrikstad, Norway
    J Psychiatry Neurosci 35:304-10. 2010
    ..In the present study, we investigated whether osteoprotegerin (OPG), a member of the tumour necrosis factor receptor family involved in calcification and inflammation, is elevated in patients with severe mental disorders...
  72. doi request reprint Self-harm in patients with schizophrenia spectrum disorders
    Erlend Mork
    National Centre for SuicideResearch and Prevention, Institute ofClinical Medicine, University of Oslo, Oslo, Norway
    Arch Suicide Res 16:111-23. 2012
    ..We conclude that while self-harm in patients with schizophrenia spectrum disorders is highly prevalent in both genders, risk factors in men and women differ in several important ways...
  73. pmc Self-esteem is associated with premorbid adjustment and positive psychotic symptoms in early psychosis
    Kristin Lie Romm
    Division of Mental Health and Addiction, Oslo University Hospital, 0407 Oslo, Norway
    BMC Psychiatry 11:136. 2011
    ..The main aims of the study were to examine whether premorbid adjustment has an impact on the subject's self-esteem, and whether lowered self-esteem contributes to the development of delusions and hallucinations...
  74. pmc Excessive substance use in bipolar disorder is associated with impaired functioning rather than clinical characteristics, a descriptive study
    Trine V Lagerberg
    Section for Psychosis Research, Oslo University Hospital, Bygg 49, Kirkevn, 166 N 0407 Oslo, Norway
    BMC Psychiatry 10:9. 2010
    ....
  75. ncbi request reprint Effect of an early detection programme on duration of untreated psychosis: part of the Scandinavian TIPS study
    Svein Friis
    Department of Research and Education, Division of Psychiatry, Ulleval University Hospital, Oslo N 0407, Norway
    Br J Psychiatry Suppl 48:s29-32. 2005
    ..It is unclear whether an early detection programme increases or decreases the number of patients with a long duration of untreated psychosis (DUP), and whether these differ from other patients with a long DUP...
  76. doi request reprint SRD5A2 is associated with increased cortisol metabolism in schizophrenia spectrum disorders
    Nils Eiel Steen
    Section for Psychosis Research, Clinic of Mental Health and Addiction, Oslo University Hospital, Ulleval Hospital, P O Box 4956 Nydalen, 0424 Oslo, Norway
    Prog Neuropsychopharmacol Biol Psychiatry 34:1500-6. 2010
    ..We investigated whether five genes involved in cortisol metabolism were associated with altered activity of cortisol metabolizing enzymes in bipolar disorder (BD) and schizophrenia spectrum disorders (SCZ)...
  77. doi request reprint Validation of the Norwegian version of the Social Functioning Scale (SFS) for schizophrenia and bipolar disorder
    Tone Hellvin
    Institute of Psychiatry, University of Oslo, Oslo University Hospital Ulleval, Oslo, Norway
    Scand J Psychol 51:525-33. 2010
    ..Thus, SFS adds valuable information as a supplement to standard clinician-rated assessment tools of social functioning, suited both for research and clinical work...
  78. doi request reprint Decreased self-reported arousal in schizophrenia during aversive picture viewing compared to bipolar disorder and healthy controls
    Sofie R Aminoff
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Psychiatry Res 185:309-14. 2011
    ..This was more pronounced in females. The presence of lifetime psychotic symptoms did not influence emotional responses...
  79. doi request reprint Stability of medication in early psychosis: a comparison between second-generation and low-dose first-generation antipsychotics
    Stein Opjordsmoen
    Department of Research and Education, Division of Psychiatry, Ulleval University Hospital, Oslo, Norway
    Early Interv Psychiatry 3:58-65. 2009
    ..This naturalistic study aims to compare discontinuation rates for low-dose first-generation versus second-generation antipsychotics in first-episode psychotic patients...
  80. doi request reprint Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE)
    Srdjan Djurovic
    Institute of Psychiatry, University of Oslo, Norway
    Psychiatry Res 168:256-8. 2009
    ..We report, for the first time, a possible involvement of MCTP2 as a potential novel susceptibility gene for schizophrenia...
  81. doi request reprint Executive function tests in early-onset psychosis: which one to choose?
    Aina Holmén
    Akershus University Hospital, Mental Health Services, Norway Department of Psychology, University of Oslo, Norway
    Scand J Psychol 53:200-5. 2012
    ..If a more elaborated neuropsychological evaluation of the executive functioning domain is needed, Stroop should be considered a complementary test...
  82. doi request reprint Associations between variants near a monoaminergic pathways gene (PHOX2B) and amygdala reactivity: a genome-wide functional imaging study
    Olga Therese Ousdal
    Oslo University Hospital, Oslo, Norway
    Twin Res Hum Genet 15:273-85. 2012
    ....
  83. doi request reprint Long-term follow-up of the TIPS early detection in psychosis study: effects on 10-year outcome
    Wenche Ten Velden Hegelstad
    Division of Psychiatry, Stavanger University Hospital, Regional Center for Clinical Research in Psychosis, Health West, Norway
    Am J Psychiatry 169:374-80. 2012
    ..The authors investigated the differences in symptoms and recovery after 10 years between regional health care sectors with and without a comprehensive program for the early detection of psychosis...
  84. doi request reprint Common sequence variants in the major histocompatibility complex region associate with cerebral ventricular size in schizophrenia
    Ingrid Agartz
    Institute of Clinical Medicine, Department of Biostatistics, University of Oslo, Oslo, Norway
    Biol Psychiatry 70:696-8. 2011
    ..3-22.1 has been implicated in the development of schizophrenia...
  85. pmc Neuropsychological profile in early-onset schizophrenia-spectrum disorders: measured with the MATRICS battery
    Aina Holmén
    Department of Psychology, University of Oslo, Norway
    Schizophr Bull 36:852-9. 2010
    ....
  86. pmc Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort
    Lavinia Athanasiu
    Institute of Psychiatry, University of Oslo, P O 1130, Blindern, N 0318 Oslo, Norway
    J Psychiatr Res 44:748-53. 2010
    ..The association of ANK3 with schizophrenia is intriguing in light of recent associations of ANK3 with bipolar disorder, thereby supporting the hypothesis of an overlap in genetic susceptibility between these psychopathological entities...
  87. pmc Apathy is associated with executive functioning in first episode psychosis
    Ann Faerden
    Ulleval University Hospital, 0407 Oslo, Norway
    BMC Psychiatry 9:1. 2009
    ....
  88. doi request reprint Evidence for a possible association of neurotrophin receptor (NTRK-3) gene polymorphisms with hippocampal function and schizophrenia
    Mona K Otnaess
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Neurobiol Dis 34:518-24. 2009
    ..The present results, although not robust, suggest that the NTRK-3 gene influences hippocampal function and may modify the risk for schizophrenia...
  89. ncbi request reprint Multifamily group treatment in a program for patients with first-episode psychosis: experiences from the TIPS project
    Anne Fjell
    Ulleval University Hospital, N 0407 Oslo, Norway
    Psychiatr Serv 58:171-3. 2007
    ..Treatment was well received by patients and families. Care should be taken to prevent a long delay before group commencement at this stressful period in the lives of patients and families...
  90. doi request reprint Cortical thickness and subcortical volumes in schizophrenia and bipolar disorder
    Lars M Rimol
    Department of Psychiatry, section Vinderen, University of Oslo, Oslo, Norway
    Biol Psychiatry 68:41-50. 2010
    ..The purpose of this study was to compare cortical thickness and subcortical volumes in schizophrenia and bipolar disorder, to assess differences and similarities in cortical and subcortical brain structure...
  91. ncbi request reprint Assessing apathy: the use of the Apathy Evaluation Scale in first episode psychosis
    Ann Faerden
    Section for Psychosis Research, Division of Psychiatry, Building 49, Ulleval University Hospital, Krikeveien 166, 0407 Oslo, Norway
    Eur Psychiatry 23:33-9. 2008
    ..The main aims of this study were to examine the psychometric properties of the AES-C and its relationship to the Positive and Negative Syndrome Scale (PANSS)...
  92. ncbi request reprint Are there common core features of apathy in different neuropsychiatric samples as assessed by the Apathy Evaluation Scale?
    Ulrike Sagen
    Institute of Basic Medical Sciences, Department of Behavioural Sciences in Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway
    Nord J Psychiatry 64:49-57. 2010
    ....
  93. ncbi request reprint Age at onset of bipolar disorder in a Norwegian catchment area sample
    Sara Larsson
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    J Affect Disord 124:174-7. 2010
    ..In addition, we examined whether age at onset influenced on time to first treatment, and if patient characteristics related to illness severity influenced age at onset...
  94. doi request reprint The validity of d prime as a working memory index: results from the "Bergen n-back task"
    Beathe C Haatveit
    Department of Psychiatry, Oslo University Hospital, Ullevaal, Norway
    J Clin Exp Neuropsychol 32:871-80. 2010
    ..d ' has the advantage of capturing executive skills needed to perform mental operations in patients with schizophrenia, without being influenced by demographic variables or IQ...
  95. doi request reprint A cross-sectional study of vitamin D deficiency among immigrants and Norwegians with psychosis compared to the general population
    Akiah Ottesen Berg
    Institute of Psychiatry, University of Oslo, Oslo University Hospital, Building 49, Kirkeveien 166, N 0407 Oslo, Norway
    J Clin Psychiatry 71:1598-604. 2010
    ..This study aimed to determine vitamin D levels among immigrants and Norwegians with psychosis compared to the general population and their association to clinical characteristics...
  96. pmc Sex-dependent association of common variants of microcephaly genes with brain structure
    Lars M Rimol
    Division of Psychiatry, Oslo University Hospital Ulleval, 0407 Oslo, Norway
    Proc Natl Acad Sci U S A 107:384-8. 2010
    ..These results are consistent with the view that common variation in brain structure is associated with genetic variants located in nonexonic, presumably regulatory, regions...
  97. ncbi request reprint No altered dorsal anterior cingulate activation in bipolar II disorder patients during a Go/No-go task: an fMRI study
    Audun S Welander-Vatn
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Bipolar Disord 11:270-9. 2009
    ..The aim of this study was to investigate whether patients with BD II showed decreased activation in the dorsal anterior cingulate cortex (dACC) as compared to healthy controls when performing a task sensitive to impulsivity...
  98. doi request reprint Passive/apathetic social withdrawal and active social avoidance in schizophrenia: difference in underlying psychological processes
    Charlotte Fredslund Hansen
    Department of Psychology, University of Oslo, Oslo, Norway
    J Nerv Ment Dis 197:274-7. 2009
    ..We examined whether this differentiation was related to differences in underlying psychological processes of object relations and reality testing...
  99. ncbi request reprint Inpatient psychotherapy compared with usual care for patients who have schizophrenic psychoses
    Edvard Hauff
    Department of Psychiatric Research and Education, Ullevaal University Hospital, Oslo, Norway
    Psychiatr Serv 53:471-3. 2002
    ..Psychotherapeutic inpatient programs may be beneficial to patients who have higher levels of global functioning at the start of treatment but detrimental to other patients...
  100. ncbi request reprint Similar immune profile in bipolar disorder and schizophrenia: selective increase in soluble tumor necrosis factor receptor I and von Willebrand factor
    Sigrun Hope
    Department of Psychiatry, Østfold Hospital, Eidsberg, Norway
    Bipolar Disord 11:726-34. 2009
    ....
  101. doi request reprint Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene
    Anna K Kähler
    TOP Project, Institute of Psychiatry, University of Oslo, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 147:1089-100. 2008
    ....