Ingrid Melle

Summary

Affiliation: University of Oslo
Country: Norway

Publications

  1. ncbi Insight and suicidal behavior in first-episode schizophrenia
    Ingrid Melle
    Division of Mental Health and Addiction, Building 49, Oslo University Hospital Ulleval, PO Box 4956, Nydalen, 0424 Oslo, Norway
    Expert Rev Neurother 12:353-9. 2012
  2. ncbi Previous hospital admissions and disease severity predict the use of antipsychotic combination treatment in patients with schizophrenia
    Albert Bolstad
    Department of Psychiatry Research, Diakonhjemmet Hospital, P O Box 85 Vinderen, Oslo 0319, Norway
    BMC Psychiatry 11:126. 2011
  3. ncbi The estrogen hypothesis of schizophrenia implicates glucose metabolism: association study in three independent samples
    Line Olsen
    Research Institute of Biological Psychiatry, Sct, Hans Hospital, DK 4000 Roskilde, Denmark
    BMC Med Genet 9:39. 2008
  4. ncbi Measuring quality of life in first-episode psychosis
    I Melle
    Department of Research and Education, Division of Psychiatry, Ulleval University Hospital, 0407 Oslo, Norway
    Eur Psychiatry 20:474-83. 2005
  5. ncbi Early detection of the first episode of schizophrenia and suicidal behavior
    Ingrid Melle
    Department of Research and Education, Division of Psychiatry, Ulleval University Hospital, N 0407 Oslo, Norway
    Am J Psychiatry 163:800-4. 2006
  6. ncbi Prevention of negative symptom psychopathologies in first-episode schizophrenia: two-year effects of reducing the duration of untreated psychosis
    Ingrid Melle
    Section for Psychosis Research, Division of Psychiatry, Ulleval University Hospital, 0407 Oslo, Norway
    Arch Gen Psychiatry 65:634-40. 2008
  7. ncbi The development of subjective quality of life over the first 2 years in first-episode psychosis
    Ingrid Melle
    Department of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    J Nerv Ment Dis 198:864-9. 2010
  8. ncbi Course and predictors of suicidality over the first two years of treatment in first-episode schizophrenia spectrum psychosis
    Ingrid Melle
    Clinic for Mental Health and Addiction, Department of Psychiatry, University of Oslo, Oslo University Hospital, Kirkeveien 166, Oslo, Norway
    Arch Suicide Res 14:158-70. 2010
  9. ncbi Subcortical brain volumes relate to neurocognition in schizophrenia and bipolar disorder and healthy controls
    Cecilie B Hartberg
    Institute of Clinical Medicine, Psychiatry Section, University of Oslo, Norway
    Prog Neuropsychopharmacol Biol Psychiatry 35:1122-30. 2011
  10. ncbi Sex-specific cortisol levels in bipolar disorder and schizophrenia during mental challenge--relationship to clinical characteristics and medication
    Nils Eiel Steen
    Psychosis Research Unit, Division of Mental Health and Addiction, Oslo University Hospital, Ulleval Hospital, P O Box 4956 Nydalen, 0424 Oslo, Norway
    Prog Neuropsychopharmacol Biol Psychiatry 35:1100-7. 2011

Detail Information

Publications109 found, 100 shown here

  1. ncbi Insight and suicidal behavior in first-episode schizophrenia
    Ingrid Melle
    Division of Mental Health and Addiction, Building 49, Oslo University Hospital Ulleval, PO Box 4956, Nydalen, 0424 Oslo, Norway
    Expert Rev Neurother 12:353-9. 2012
    ..In this article, we will present a review of studies illustrating the complex background of suicide risk in schizophrenia, with a particular emphasis on the role of insight in the early phases of schizophrenia...
  2. ncbi Previous hospital admissions and disease severity predict the use of antipsychotic combination treatment in patients with schizophrenia
    Albert Bolstad
    Department of Psychiatry Research, Diakonhjemmet Hospital, P O Box 85 Vinderen, Oslo 0319, Norway
    BMC Psychiatry 11:126. 2011
    ....
  3. ncbi The estrogen hypothesis of schizophrenia implicates glucose metabolism: association study in three independent samples
    Line Olsen
    Research Institute of Biological Psychiatry, Sct, Hans Hospital, DK 4000 Roskilde, Denmark
    BMC Med Genet 9:39. 2008
    ..Thus, we tested the hypothesis that variants of the glycolytic genes are associated with schizophrenia or at least with gender-associated aspects of the illness...
  4. ncbi Measuring quality of life in first-episode psychosis
    I Melle
    Department of Research and Education, Division of Psychiatry, Ulleval University Hospital, 0407 Oslo, Norway
    Eur Psychiatry 20:474-83. 2005
    ....
  5. ncbi Early detection of the first episode of schizophrenia and suicidal behavior
    Ingrid Melle
    Department of Research and Education, Division of Psychiatry, Ulleval University Hospital, N 0407 Oslo, Norway
    Am J Psychiatry 163:800-4. 2006
    ..Treatment programs that bring first-episode patients into treatment at lower symptom levels can have the potential to reduce risk for suicide attempts...
  6. ncbi Prevention of negative symptom psychopathologies in first-episode schizophrenia: two-year effects of reducing the duration of untreated psychosis
    Ingrid Melle
    Section for Psychosis Research, Division of Psychiatry, Ulleval University Hospital, 0407 Oslo, Norway
    Arch Gen Psychiatry 65:634-40. 2008
    ..The duration of untreated psychosis (DUP)-the time from onset of psychotic symptoms to the start of adequate treatment--is consistently correlated with better course and outcome, but the mechanisms are poorly understood...
  7. ncbi The development of subjective quality of life over the first 2 years in first-episode psychosis
    Ingrid Melle
    Department of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    J Nerv Ment Dis 198:864-9. 2010
    ..Improvements in general s-QoL were associated with increase in excitative symptoms and with improvements in depressive symptoms, global functioning, level of daily activities, level of social activities, and perceived general health...
  8. ncbi Course and predictors of suicidality over the first two years of treatment in first-episode schizophrenia spectrum psychosis
    Ingrid Melle
    Clinic for Mental Health and Addiction, Department of Psychiatry, University of Oslo, Oslo University Hospital, Kirkeveien 166, Oslo, Norway
    Arch Suicide Res 14:158-70. 2010
    ..Severe suicidality (plans and attempts) was predicted by drug abuse, dissatisfaction with life and severe suicidality at start of treatment...
  9. ncbi Subcortical brain volumes relate to neurocognition in schizophrenia and bipolar disorder and healthy controls
    Cecilie B Hartberg
    Institute of Clinical Medicine, Psychiatry Section, University of Oslo, Norway
    Prog Neuropsychopharmacol Biol Psychiatry 35:1122-30. 2011
    ..It is unknown whether relationships between subcortical volumes and neurocognitive performance are similar or different between schizophrenia and bipolar disorder...
  10. ncbi Sex-specific cortisol levels in bipolar disorder and schizophrenia during mental challenge--relationship to clinical characteristics and medication
    Nils Eiel Steen
    Psychosis Research Unit, Division of Mental Health and Addiction, Oslo University Hospital, Ulleval Hospital, P O Box 4956 Nydalen, 0424 Oslo, Norway
    Prog Neuropsychopharmacol Biol Psychiatry 35:1100-7. 2011
    ....
  11. ncbi Suicidality before and in the early phases of first episode psychosis
    Elizabeth A Barrett
    Department of Mental Health, Oslo University Hospital, 0514 Oslo, Norway
    Schizophr Res 119:11-7. 2010
    ..This study explored the prevalence and characteristics of suicidality in patients with a first episode of psychosis (FEP) in two time intervals: 1) prior to study entry and 2) explicitly in the period of untreated psychosis...
  12. ncbi Depression and depressive symptoms in first episode psychosis
    Kristin Lie Romm
    Department of Psychiatry, Oslo University Hospital, Ulleval, Oslo, Norway
    J Nerv Ment Dis 198:67-71. 2010
    ..Thus depressive symptoms are frequent among FEPP, with indications of gender specific differences in patient characteristics that might imply different approaches to treatment...
  13. ncbi Suicidality in first episode psychosis is associated with insight and negative beliefs about psychosis
    Elizabeth A Barrett
    Department of Mental Health and Addiction, Oslo University Hospital, 0424 Oslo, Norway
    Schizophr Res 123:257-62. 2010
    ....
  14. ncbi Cardiovascular risk factors during second generation antipsychotic treatment are associated with increased C-reactive protein
    Ingrid Dieset
    Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    Schizophr Res 140:169-74. 2012
    ..We investigated whether there is a relationship between CVD risk factors and inflammation in schizophrenia or bipolar disorder, and if second generation antipsychotics (SGA) interact...
  15. ncbi Factors associated with occupational and academic status in patients with first-episode psychosis with a particular focus on neurocognition
    Marte Tandberg
    Division of Mental Health and Addiction, Oslo University Hospital, 0407 Oslo, Norway
    Soc Psychiatry Psychiatr Epidemiol 47:1763-73. 2012
    ..Further, it investigated the relationship between students, employed and unemployed patients and clinical, neurocognitive, global, and social functioning...
  16. ncbi Apathy in first episode psychosis patients: a ten year longitudinal follow-up study
    Julie Evensen
    Division of Mental Health and Addiction, Oslo University Hospital, N 0407, Oslo, Norway
    Schizophr Res 136:19-24. 2012
    ..Apathy is a common symptom in first episode psychosis (FEP), and is associated with poor functioning. Prevalence and correlates of apathy 10 years after the first psychotic episode remain unexplored...
  17. ncbi Association analysis of ANK3 gene variants in nordic bipolar disorder and schizophrenia case-control samples
    Martin Tesli
    Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 156:969-74. 2011
    ..These results further support that ANK3 is a susceptibility gene specific to BD and that more than one risk locus is involved...
  18. ncbi Association study of PDE4B gene variants in Scandinavian schizophrenia and bipolar disorder multicenter case-control samples
    Anna K Kähler
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 153:86-96. 2010
    ..Further studies are needed to evaluate the implicated PDE4B region of interest, for potential involvement in SZ and BP susceptibility...
  19. ncbi Neurocognitive functioning and suicidality in schizophrenia spectrum disorders
    Elizabeth A Barrett
    Department of Mental Health and Addiction, Oslo University Hospital, 0424 Oslo, Norway
    Compr Psychiatry 52:156-63. 2011
    ....
  20. ncbi Neurocognition and occupational functioning in patients with first-episode psychosis: a 2-year follow-up study
    Marte Tandberg
    Division of Mental Health and Addiction, Oslo University Hospital, 0407 Oslo, Norway
    Psychiatry Res 188:334-42. 2011
    ..For those unemployed at baseline, none of the variables predicted change in employment status. Implications of these results are discussed...
  21. ncbi Dysbindin and d-amino-acid-oxidase gene polymorphisms associated with positive and negative symptoms in schizophrenia
    Katrine V Wirgenes
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Neuropsychobiology 60:31-6. 2009
    ....
  22. ncbi Neurocognitive dysfunction in bipolar and schizophrenia spectrum disorders depends on history of psychosis rather than diagnostic group
    Carmen Simonsen
    Department of Psychology, University of Oslo, 0317 Oslo, Norway
    Schizophr Bull 37:73-83. 2011
    ..We asked whether neurocognitive dysfunction in bipolar and schizophrenia spectrum disorders depends more on history of psychosis than diagnostic category or subtype...
  23. ncbi Sex differences in neuropsychological performance and social functioning in schizophrenia and bipolar disorder
    Anja Vaskinn
    Oslo University Hospital, Psychosis Research Unit, Oslo, Norway
    Neuropsychology 25:499-510. 2011
    ..To investigate sex differences in neurocognition and social functioning in schizophrenia and bipolar disorder and the possible role of sex as a moderator of this relationship...
  24. ncbi A comparison of adolescent- and adult-onset first-episode, non-affective psychosis: 2-year follow-up
    Johannes Langeveld
    Department of Psychiatry, Regional Centre for Clinical Research in Psychosis, Stavanger University Hospital, Norway
    Eur Arch Psychiatry Clin Neurosci 262:599-605. 2012
    ..Our results indicate that adolescent-onset and adult-onset psychosis have similar prognostic trajectories, although both may predict a qualitatively different course from childhood-onset psychosis...
  25. ncbi Flat affect and social functioning: a 10 year follow-up study of first episode psychosis patients
    Julie Evensen
    Division of Mental Health and Addiction, Oslo University Hospital, N 0407, Oslo, Norway
    Schizophr Res 139:99-104. 2012
    ..Affective flattening has been described as enduring, but long term follow-up studies of first episode psychosis patients are lacking...
  26. ncbi Genome-wide association study identifies genetic loci associated with body mass index and high density lipoprotein-cholesterol levels during psychopharmacological treatment - a cross-sectional naturalistic study
    Lavinia Athanasiu
    Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    Psychiatry Res 197:327-36. 2012
    ..This deserves to be replicated in additional populations to provide more evidence for molecular genetic mechanisms of side effects during psychopharmacological treatment...
  27. ncbi Neurocognitive functioning in patients recently diagnosed with bipolar disorder
    Tone Hellvin
    Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    Bipolar Disord 14:227-38. 2012
    ..In this study we compare neurocognitive function in a cohort of first-contact mania patients with a healthy control group matched for age, gender, and education...
  28. ncbi Affective symptoms are associated with markers of inflammation and immune activation in bipolar disorders but not in schizophrenia
    Sigrun Hope
    Department of Psychiatry, Østfold Hospital, Fredrikstad, Norway
    J Psychiatr Res 45:1608-16. 2011
    ..We aimed to determine if immune markers that consistently have been reported elevated in BP were associated with depressive and manic symptoms, and if this was specific for BP...
  29. ncbi A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample
    Srdjan Djurovic
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    J Affect Disord 126:312-6. 2010
    ..In the present study we investigated genetic variants associated with bipolar disorder in a homogenous Norwegian sample, and potential genetic overlap with schizophrenia, using the Affymetrix 6.0 array...
  30. ncbi Psychosocial function in schizophrenia and bipolar disorder: Relationship to neurocognition and clinical symptoms
    Carmen Simonsen
    Psychosis Research Section, Oslo University Hospital, Oslo, Norway
    J Int Neuropsychol Soc 16:771-83. 2010
    ..Despite differences in neurocognition and psychosocial function, groups showed the same pattern in prediction of functioning irrespective of DSM-IV or clinical definition...
  31. ncbi Catechol O-methyltransferase variants and cognitive performance in schizophrenia and bipolar disorder versus controls
    Katrine V Wirgenes
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Schizophr Res 122:31-7. 2010
    ..However, the results have been inconsistent and there are few studies addressing other COMT single nucleotide polymorphisms (SNPs)...
  32. ncbi Apathy in first episode psychosis patients: one year follow up
    Ann Faerden
    Oslo University Hospital, Ulleval, 0407 Oslo, Norway
    Schizophr Res 116:20-6. 2010
    ....
  33. ncbi Is cognitive impairment following early life stress in severe mental disorders based on specific or general cognitive functioning?
    Monica Aas
    Institute of Clinical Medicine, University of Oslo, Norway
    Psychiatry Res 198:495-500. 2012
    ..Moreover, these dysfunctions seem to be driven by underlying deficits in general cognitive tasks as measured by the WASI...
  34. ncbi Severe social anxiety in early psychosis is associated with poor premorbid functioning, depression, and reduced quality of life
    Kristin Lie Romm
    Psychosis Research Unit, Division of Mental Health and Addiction, Oslo University Hospital, 0407 Oslo, Norway
    Compr Psychiatry 53:434-40. 2012
    ..quot; Furthermore, we wanted to explore whether social anxiety is associated with reduced quality of life (QoL)...
  35. ncbi Treatment delay and excessive substance use in bipolar disorder
    Trine Vik Lagerberg
    Psychosis Research Unit, Division of Mental Health and Addiction, Department of Research and Development, Oslo University Hospital, Oslo, Norway
    J Nerv Ment Dis 198:628-33. 2010
    ..Patients with antecedent excessive substance use had reduced risk of long treatment delays. The risk of developing excessive substance use after BD onset increased with longer treatment delays...
  36. ncbi Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area
    Anna K Kähler
    Institute of Psychiatry, University of Oslo, Oslo University Hospital Ulleval, Norway
    Biol Psychiatry 69:90-6. 2011
    ..Extracellular matrix structures called perineuronal nets, condensed around subsets of neurons and proximal dendrites during brain maturation, regulate synaptic transmission and plasticity...
  37. ncbi Pathways to care for first-episode psychosis in an early detection healthcare sector: part of the Scandinavian TIPS study
    Jan Olav Johannessen
    Division of Psychiatry, General Hospital of Rogaland, Armauer Hanssens vei 20, 4000 Stavanger, Norway
    Br J Psychiatry Suppl 48:s24-8. 2005
    ..Early detection programmes aim to reduce the duration of untreated psychosis (DUP) by public education and by prompt access to treatment via active outreach detection teams...
  38. ncbi The course of neurocognitive functioning in first-episode psychosis and its relation to premorbid adjustment, duration of untreated psychosis, and relapse
    Bjørn Rishovd Rund
    Department of Psychology, University of Oslo, P O Box 1094 Blindern, N 0317 Oslo, Norway
    Schizophr Res 91:132-40. 2007
    ..More severe deficits in WM and VL are associated with more relapses during the first year. It is unclear whether NP deficits cause relapse, relapse causes NP deficits, or both are manifestations of a third deteriorative process...
  39. ncbi Object relations, reality testing, and social withdrawal in schizophrenia and bipolar disorder
    Charlotte Fredslund Hansen
    Department of Psychology, University of Oslo Psychosis Research Unit, Oslo University Hospital Psychosis Research Centre, Institute of Clinical Medicine, University of Oslo, Oslo, Norway and Yale University, School of Medicine, New Haven, CT
    J Nerv Ment Dis 201:222-5. 2013
    ..These two measures, together with the level of alienation, explained a significant amount of variance in self-experienced social dysfunction. Findings reveal the multidimensional nature of social dysfunction in severe mental disorders...
  40. ncbi Effect of DISC1 SNPs on brain structure in healthy controls and patients with a history of psychosis
    Anna K Kähler
    Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 159:722-30. 2012
    ..In conclusion, DISC1 SNPs might impact brain structural variation, possibly differently in psychosis patients versus controls, but independent replication will be needed to confirm our findings...
  41. ncbi Object relations and reality testing in schizophrenia, bipolar disorders, and healthy controls: differences in profiles and clinical correlates
    Charlotte Fredslund Hansen
    Department of Psychology, University of Oslo, Norway
    Compr Psychiatry 53:1200-7. 2012
    ..In the current study, we examine if there are OR and RT differences in schizophrenia and bipolar disorder compared to healthy controls and to what extent differences in clinical characteristics mediates the putative effect of diagnosis...
  42. ncbi Up-regulation of NOTCH4 gene expression in bipolar disorder
    Ingrid Dieset
    Division of Mental Health and Addiction, Oslo University Hospital Ulleval, Oslo, Norway
    Am J Psychiatry 169:1292-300. 2012
    ..The authors investigated the NOTCH4 gene expression in individuals with bipolar disorder and schizophrenia relative to healthy comparison subjects and identified putative expression quantitative trait loci in and around the NOTCH4 gene...
  43. ncbi Genome-wide study identifies PTPRO and WDR72 and FOXQ1-SUMO1P1 interaction associated with neurocognitive function
    Marissa Leblanc
    Epi Gen, Institute of Clinical Medicine, Akershus University Hospital, University of Oslo, Oslo, Norway
    J Psychiatr Res 46:271-8. 2012
    ..We performed a genome-wide association study (GWAS) to identify genes associated with neurocognition...
  44. ncbi Cortical volume, surface area, and thickness in schizophrenia and bipolar disorder
    Lars M Rimol
    Division of Mental Health and Addiction, Institute of Clinical Medicine, University of Oslo, Norway
    Biol Psychiatry 71:552-60. 2012
    ....
  45. ncbi Serotonin transporter gene polymorphism, childhood trauma, and cognition in patients with psychotic disorders
    Monica Aas
    Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    Schizophr Bull 38:15-22. 2012
    ..We hypothesize that 5-HTTLPR variations and long-term effects of childhood trauma interact and contribute to some of the variation in cognitive dysfunction seen in patients with psychotic disorders...
  46. ncbi Reducing the duration of untreated first-episode psychosis: effects on clinical presentation
    Ingrid Melle
    Division of Psychiatry, Ullevaal University Hospital, Oslo, Norway
    Arch Gen Psychiatry 61:143-50. 2004
    ..Most studies on first-episode psychosis show an association between a long duration of untreated psychosis (DUP) and poorer short-term outcome, but the mechanisms of this relationship are poorly understood...
  47. ncbi Neurocognitive dysfunction in first-episode psychosis: correlates with symptoms, premorbid adjustment, and duration of untreated psychosis
    Bjørn Rishovd Rund
    Department of Psychiatry, Ulleval University Hospital, Oslo, Norway
    Am J Psychiatry 161:466-72. 2004
    ....
  48. ncbi Excessive cannabis use is associated with earlier age at onset in bipolar disorder
    Trine V Lagerberg
    Department of Research and Development, Division of Mental Health and Addiction, Oslo University Hospital, Norway
    Eur Arch Psychiatry Clin Neurosci 261:397-405. 2011
    ..This indicates that an early onset may increase the risk of cannabis use and that cannabis use may trigger bipolar disorder in vulnerable individuals...
  49. ncbi Intron 12 in NTRK3 is associated with bipolar disorder
    Lavinia Athanasiu
    Department of Psychiatry, Oslo University Hospital Ulleval, Oslo, Norway
    Psychiatry Res 185:358-62. 2011
    ....
  50. ncbi Perceived discrimination is associated with severity of positive and depression/anxiety symptoms in immigrants with psychosis: a cross-sectional study
    Akiah O Berg
    Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway
    BMC Psychiatry 11:77. 2011
    ..We investigated if perceived discrimination was associated with the severity of these symptoms among immigrants in Norway with psychotic disorders...
  51. ncbi The use of screening instruments for detecting alcohol and other drug use disorders in first-episode psychosis
    Ragnar Nesvåg
    Department of Psychiatry, Diakonhjemmet Hospital, Oslo, Norway
    Psychiatry Res 177:228-34. 2010
    ..The results of this study suggest that AUDIT and DUDIT are powerful screening instruments for detecting alcohol and other drug use disorders in patients with first-episode psychosis...
  52. ncbi Association analysis of PALB2 and BRCA2 in bipolar disorder and schizophrenia in a scandinavian case-control sample
    Martin Tesli
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 153:1276-82. 2010
    ..Our findings support PALB2 and BRCA2 as risk genes specifically for BD, and suggest that altered DNA repair related to neurogenesis may be involved in BD pathophysiology. © 2010 Wiley-Liss, Inc...
  53. ncbi Contrasting monosymptomatic patients with hallucinations and delusions in first-episode psychosis patients: a five-year longitudinal follow-up study
    Julie Evensen
    Division of Psychiatry, Oslo University Hospital, Oslo, Norway
    Psychopathology 44:90-7. 2011
    ....
  54. ncbi Increased systemic cortisol metabolism in patients with schizophrenia and bipolar disorder: a mechanism for increased stress vulnerability?
    Nils Eiel Steen
    Section for Psychosis Research, Clinic of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    J Clin Psychiatry 72:1515-21. 2011
    ....
  55. ncbi Apathy and functioning in first-episode psychosis
    Ann Faerden
    Department of Psychiatry, Ulleval University Hospital, Oslo, Norway
    Psychiatr Serv 60:1495-503. 2009
    ....
  56. ncbi Osteoprotegerin levels in patients with severe mental disorders
    Sigrun Hope
    Department of Psychiatry, Østfold Hospital, Fredrikstad, Norway
    J Psychiatry Neurosci 35:304-10. 2010
    ..In the present study, we investigated whether osteoprotegerin (OPG), a member of the tumour necrosis factor receptor family involved in calcification and inflammation, is elevated in patients with severe mental disorders...
  57. ncbi Self-harm in patients with schizophrenia spectrum disorders
    Erlend Mork
    National Centre for SuicideResearch and Prevention, Institute ofClinical Medicine, University of Oslo, Oslo, Norway
    Arch Suicide Res 16:111-23. 2012
    ..We conclude that while self-harm in patients with schizophrenia spectrum disorders is highly prevalent in both genders, risk factors in men and women differ in several important ways...
  58. ncbi Excessive substance use in bipolar disorder is associated with impaired functioning rather than clinical characteristics, a descriptive study
    Trine V Lagerberg
    Section for Psychosis Research, Oslo University Hospital, Bygg 49, Kirkevn, 166 N 0407 Oslo, Norway
    BMC Psychiatry 10:9. 2010
    ....
  59. ncbi Self-esteem is associated with premorbid adjustment and positive psychotic symptoms in early psychosis
    Kristin Lie Romm
    Division of Mental Health and Addiction, Oslo University Hospital, 0407 Oslo, Norway
    BMC Psychiatry 11:136. 2011
    ..The main aims of the study were to examine whether premorbid adjustment has an impact on the subject's self-esteem, and whether lowered self-esteem contributes to the development of delusions and hallucinations...
  60. ncbi Stability of medication in early psychosis: a comparison between second-generation and low-dose first-generation antipsychotics
    Stein Opjordsmoen
    Department of Research and Education, Division of Psychiatry, Ulleval University Hospital, Oslo, Norway
    Early Interv Psychiatry 3:58-65. 2009
    ..This naturalistic study aims to compare discontinuation rates for low-dose first-generation versus second-generation antipsychotics in first-episode psychotic patients...
  61. ncbi Decreased self-reported arousal in schizophrenia during aversive picture viewing compared to bipolar disorder and healthy controls
    Sofie R Aminoff
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Psychiatry Res 185:309-14. 2011
    ..This was more pronounced in females. The presence of lifetime psychotic symptoms did not influence emotional responses...
  62. ncbi Validation of the Norwegian version of the Social Functioning Scale (SFS) for schizophrenia and bipolar disorder
    Tone Hellvin
    Institute of Psychiatry, University of Oslo, Oslo University Hospital Ulleval, Oslo, Norway
    Scand J Psychol 51:525-33. 2010
    ..Thus, SFS adds valuable information as a supplement to standard clinician-rated assessment tools of social functioning, suited both for research and clinical work...
  63. ncbi Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE)
    Srdjan Djurovic
    Institute of Psychiatry, University of Oslo, Norway
    Psychiatry Res 168:256-8. 2009
    ..We report, for the first time, a possible involvement of MCTP2 as a potential novel susceptibility gene for schizophrenia...
  64. ncbi SRD5A2 is associated with increased cortisol metabolism in schizophrenia spectrum disorders
    Nils Eiel Steen
    Section for Psychosis Research, Clinic of Mental Health and Addiction, Oslo University Hospital, Ulleval Hospital, P O Box 4956 Nydalen, 0424 Oslo, Norway
    Prog Neuropsychopharmacol Biol Psychiatry 34:1500-6. 2010
    ..We investigated whether five genes involved in cortisol metabolism were associated with altered activity of cortisol metabolizing enzymes in bipolar disorder (BD) and schizophrenia spectrum disorders (SCZ)...
  65. ncbi Effect of an early detection programme on duration of untreated psychosis: part of the Scandinavian TIPS study
    Svein Friis
    Department of Research and Education, Division of Psychiatry, Ulleval University Hospital, Oslo N 0407, Norway
    Br J Psychiatry Suppl 48:s29-32. 2005
    ..It is unclear whether an early detection programme increases or decreases the number of patients with a long duration of untreated psychosis (DUP), and whether these differ from other patients with a long DUP...
  66. ncbi Associations between variants near a monoaminergic pathways gene (PHOX2B) and amygdala reactivity: a genome-wide functional imaging study
    Olga Therese Ousdal
    Oslo University Hospital, Oslo, Norway
    Twin Res Hum Genet 15:273-85. 2012
    ....
  67. ncbi Executive function tests in early-onset psychosis: which one to choose?
    Aina Holmén
    Akershus University Hospital, Mental Health Services, Norway Department of Psychology, University of Oslo, Norway
    Scand J Psychol 53:200-5. 2012
    ..If a more elaborated neuropsychological evaluation of the executive functioning domain is needed, Stroop should be considered a complementary test...
  68. ncbi Long-term follow-up of the TIPS early detection in psychosis study: effects on 10-year outcome
    Wenche Ten Velden Hegelstad
    Division of Psychiatry, Stavanger University Hospital, Regional Center for Clinical Research in Psychosis, Health West, Norway
    Am J Psychiatry 169:374-80. 2012
    ..The authors investigated the differences in symptoms and recovery after 10 years between regional health care sectors with and without a comprehensive program for the early detection of psychosis...
  69. ncbi Common sequence variants in the major histocompatibility complex region associate with cerebral ventricular size in schizophrenia
    Ingrid Agartz
    Institute of Clinical Medicine, Department of Biostatistics, University of Oslo, Oslo, Norway
    Biol Psychiatry 70:696-8. 2011
    ..3-22.1 has been implicated in the development of schizophrenia...
  70. ncbi Neuropsychological profile in early-onset schizophrenia-spectrum disorders: measured with the MATRICS battery
    Aina Holmén
    Department of Psychology, University of Oslo, Norway
    Schizophr Bull 36:852-9. 2010
    ....
  71. ncbi Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort
    Lavinia Athanasiu
    Institute of Psychiatry, University of Oslo, P O 1130, Blindern, N 0318 Oslo, Norway
    J Psychiatr Res 44:748-53. 2010
    ..The association of ANK3 with schizophrenia is intriguing in light of recent associations of ANK3 with bipolar disorder, thereby supporting the hypothesis of an overlap in genetic susceptibility between these psychopathological entities...
  72. ncbi Apathy is associated with executive functioning in first episode psychosis
    Ann Faerden
    Ulleval University Hospital, 0407 Oslo, Norway
    BMC Psychiatry 9:1. 2009
    ....
  73. ncbi Evidence for a possible association of neurotrophin receptor (NTRK-3) gene polymorphisms with hippocampal function and schizophrenia
    Mona K Otnaess
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Neurobiol Dis 34:518-24. 2009
    ..The present results, although not robust, suggest that the NTRK-3 gene influences hippocampal function and may modify the risk for schizophrenia...
  74. ncbi Cortical thickness and subcortical volumes in schizophrenia and bipolar disorder
    Lars M Rimol
    Department of Psychiatry, section Vinderen, University of Oslo, Oslo, Norway
    Biol Psychiatry 68:41-50. 2010
    ..The purpose of this study was to compare cortical thickness and subcortical volumes in schizophrenia and bipolar disorder, to assess differences and similarities in cortical and subcortical brain structure...
  75. ncbi Multifamily group treatment in a program for patients with first-episode psychosis: experiences from the TIPS project
    Anne Fjell
    Ulleval University Hospital, N 0407 Oslo, Norway
    Psychiatr Serv 58:171-3. 2007
    ..Treatment was well received by patients and families. Care should be taken to prevent a long delay before group commencement at this stressful period in the lives of patients and families...
  76. ncbi Assessing apathy: the use of the Apathy Evaluation Scale in first episode psychosis
    Ann Faerden
    Section for Psychosis Research, Division of Psychiatry, Building 49, Ulleval University Hospital, Krikeveien 166, 0407 Oslo, Norway
    Eur Psychiatry 23:33-9. 2008
    ..The main aims of this study were to examine the psychometric properties of the AES-C and its relationship to the Positive and Negative Syndrome Scale (PANSS)...
  77. ncbi Are there common core features of apathy in different neuropsychiatric samples as assessed by the Apathy Evaluation Scale?
    Ulrike Sagen
    Institute of Basic Medical Sciences, Department of Behavioural Sciences in Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway
    Nord J Psychiatry 64:49-57. 2010
    ....
  78. ncbi Age at onset of bipolar disorder in a Norwegian catchment area sample
    Sara Larsson
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    J Affect Disord 124:174-7. 2010
    ..In addition, we examined whether age at onset influenced on time to first treatment, and if patient characteristics related to illness severity influenced age at onset...
  79. ncbi A cross-sectional study of vitamin D deficiency among immigrants and Norwegians with psychosis compared to the general population
    Akiah Ottesen Berg
    Institute of Psychiatry, University of Oslo, Oslo University Hospital, Building 49, Kirkeveien 166, N 0407 Oslo, Norway
    J Clin Psychiatry 71:1598-604. 2010
    ..This study aimed to determine vitamin D levels among immigrants and Norwegians with psychosis compared to the general population and their association to clinical characteristics...
  80. ncbi The validity of d prime as a working memory index: results from the "Bergen n-back task"
    Beathe C Haatveit
    Department of Psychiatry, Oslo University Hospital, Ullevaal, Norway
    J Clin Exp Neuropsychol 32:871-80. 2010
    ..d ' has the advantage of capturing executive skills needed to perform mental operations in patients with schizophrenia, without being influenced by demographic variables or IQ...
  81. ncbi Passive/apathetic social withdrawal and active social avoidance in schizophrenia: difference in underlying psychological processes
    Charlotte Fredslund Hansen
    Department of Psychology, University of Oslo, Oslo, Norway
    J Nerv Ment Dis 197:274-7. 2009
    ..We examined whether this differentiation was related to differences in underlying psychological processes of object relations and reality testing...
  82. ncbi Inpatient psychotherapy compared with usual care for patients who have schizophrenic psychoses
    Edvard Hauff
    Department of Psychiatric Research and Education, Ullevaal University Hospital, Oslo, Norway
    Psychiatr Serv 53:471-3. 2002
    ..Psychotherapeutic inpatient programs may be beneficial to patients who have higher levels of global functioning at the start of treatment but detrimental to other patients...
  83. ncbi Sex-dependent association of common variants of microcephaly genes with brain structure
    Lars M Rimol
    Division of Psychiatry, Oslo University Hospital Ulleval, 0407 Oslo, Norway
    Proc Natl Acad Sci U S A 107:384-8. 2010
    ..These results are consistent with the view that common variation in brain structure is associated with genetic variants located in nonexonic, presumably regulatory, regions...
  84. ncbi No altered dorsal anterior cingulate activation in bipolar II disorder patients during a Go/No-go task: an fMRI study
    Audun S Welander-Vatn
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Bipolar Disord 11:270-9. 2009
    ..The aim of this study was to investigate whether patients with BD II showed decreased activation in the dorsal anterior cingulate cortex (dACC) as compared to healthy controls when performing a task sensitive to impulsivity...
  85. ncbi Similar immune profile in bipolar disorder and schizophrenia: selective increase in soluble tumor necrosis factor receptor I and von Willebrand factor
    Sigrun Hope
    Department of Psychiatry, Østfold Hospital, Eidsberg, Norway
    Bipolar Disord 11:726-34. 2009
    ....
  86. ncbi The relationship between staff members' working conditions and patients' perceptions of the treatment environment
    Jan Ivar Rossberg
    Ullevaal University Hospital, 0407 Oslo, Norway
    Int J Soc Psychiatry 54:437-46. 2008
    ..The psychosocial climate of inpatient units has proved to be related to both patient satisfaction and outcome...
  87. ncbi No association between DGKH and bipolar disorder in a Scandinavian case-control sample
    Martin Tesli
    Institute of Psychiatry, Faculty Division Akershus University Hospital, University of Oslo, Oslo, Norway
    Psychiatr Genet 19:269-72. 2009
    ..We found no significant association after multiple-testing correction between any of these SNPs and BD in our sample. Thus, it is unlikely that these genetic variations confer susceptibility to BD in this large Scandinavian sample...
  88. ncbi Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene
    Anna K Kähler
    TOP Project, Institute of Psychiatry, University of Oslo, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 147:1089-100. 2008
    ....
  89. ncbi Reducing the duration of untreated first-episode psychosis -- effects on baseline social functioning and quality of life
    I Melle
    Department of Psychiatry, Yale University, New Haven, CT, USA
    Acta Psychiatr Scand 112:469-73. 2005
    ..The TIPS study demonstrated that DUP can be reduced through early detection (ED). As quality of life (QoL) is associated with DUP it is expected that reduction of DUP leads to better QoL...
  90. ncbi Differences in prevalence and patterns of substance use in schizophrenia and bipolar disorder
    P A Ringen
    Institute of Psychiatry, Medical Faculty, University of Oslo, Oslo, Norway
    Psychol Med 38:1241-9. 2008
    ..The objective of the present study was to compare the prevalence of substance use in schizophrenia and bipolar disorder, and investigate possible differences in pattern and frequency of use...
  91. ncbi Illicit drug use in patients with psychotic disorders compared with that in the general population: a cross-sectional study
    P A Ringen
    Institute of Psychiatry, University of Oslo, N 0317 Oslo, Norway, and Division of Psychiatry, Ulleval University Hospital, N 0407 Oslo, Norway
    Acta Psychiatr Scand 117:133-8. 2008
    ..Prevalence estimates of illicit drug use in psychotic disorders vary between studies, and only a few studies compared prevalence estimates with those in the general population...
  92. ncbi A 2-year follow-up of involuntary admission's influence upon adherence and outcome in first-episode psychosis
    S Opjordsmoen
    Department of Psychiatry, Oslo University Hospital, Ullevål and Institute of Psychiatry, University of Oslo, Norway
    Acta Psychiatr Scand 121:371-6. 2010
    ..To see, if voluntary admission for treatment in first-episode psychosis results in better adherence to treatment and more favourable outcome than involuntary admission...
  93. ncbi Are multi family groups appropriate for patients with first episode psychosis? A 5-year naturalistic follow-up study
    Jan Ivar Rossberg
    Department of Psychiatry, Oslo University Hospital, Ulleval, Kirkevn, Oslo, Norway
    Acta Psychiatr Scand 122:384-94. 2010
    ..To compare outcome over 5 years for patients who participated in multi family groups (MFGs) to those who refused or were not offered participation...
  94. ncbi A possible association between schizophrenia and GRIK3 polymorphisms in a multicenter sample of Scandinavian origin (SCOPE)
    S Djurovic
    Institute of Psychiatry, University of Oslo, and Department of Medical Genetics, Division of Psychiatry, Ulleval University Hospital Oslo, Oslo, Norway
    Schizophr Res 107:242-8. 2009
    ..The present results, although not robust, support the importance of more extensive investigations of GRIK3, given its potential role in mediating risk for schizophrenia...
  95. ncbi The level of illicit drug use is related to symptoms and premorbid functioning in severe mental illness
    P A Ringen
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Acta Psychiatr Scand 118:297-304. 2008
    ..This study aims to investigate if the amount of illicit psychoactive drug use is related to symptom load or premorbid functioning across diagnosis in patients with severe mental illness...
  96. ncbi Assessment of social anxiety in first episode psychosis using the Liebowitz Social Anxiety scale as a self-report measure
    K L Romm
    Psychosis Research Unit, Division of Mental Health and Addiction, Oslo University Hospital, 0407 Oslo, Norway
    Eur Psychiatry 26:115-21. 2011
    ....
  97. ncbi Opposite relationships between cannabis use and neurocognitive functioning in bipolar disorder and schizophrenia
    P A Ringen
    Institute of Psychiatry, University of Oslo, N 0318 Oslo, Norway
    Psychol Med 40:1337-47. 2010
    ..The aim of this study was to investigate the association between cannabis use and neurocognition in bipolar disorder compared with schizophrenia in a naturalistic setting...
  98. ncbi Patient satisfaction and treatment environment: a 20-year follow-up study from an acute psychiatric ward
    J I Røssberg
    Department of Psychiatry, Ulleval University Hospital, Oslo, Norway
    Nord J Psychiatry 60:176-80. 2006
    ..Changes in these WAS subscales seems to be paralleled by changes in patient satisfaction in the expected direction...
  99. ncbi Early detection and intervention in first-episode schizophrenia: a critical review
    T K Larsen
    University of Oslo, Norway, Roskilde County Psychiatric Hospital Fjorden, Denmark, Rogaland Psychiatric Hospital, Norway, , Oslo, Norway
    Acta Psychiatr Scand 103:323-34. 2001
    ..At the time being reduction of DUP seems to be the most promising strategy. Intervention in the prodromal phase is more ethically and conceptually problematic...
  100. ncbi Does duration of untreated psychosis bias study samples of first-episode psychosis?
    S Friis
    Department of Psychiatry, Ulleval University Hospital, Oslo, Norway
    Acta Psychiatr Scand 110:286-91. 2004
    ..Our questions were: (i) What is the percentage of refusers? (ii) Are there systematic differences between refusers and consenters on DUP and/or other admission variables? (iii) What is the risk of refusal for different values of DUP?..
  101. ncbi Methodological pitfalls in early detection studies - the NAPE Lecture 2002. Nordic Association for Psychiatric Epidemiology
    S Friis
    Division of Psychiatry, Ulleval University Hospital, Oslo, Norway
    Acta Psychiatr Scand 107:3-9. 2003
    ..To identify and discuss methodological pitfalls that may help explain why many questions around early detection (ED) and duration of untreated psychosis (DUP) are still unsolved...