Abdullah S Madhun

Summary

Affiliation: University of Bergen
Country: Norway

Publications

  1. pmc Pandemic influenza vaccines - the challenges
    Lars R Haaheim
    Myrdalskogen 95, N 5117 Ulset, Norway
    Viruses 1:1089-109. 2009
  2. doi Intramuscular Matrix-M-adjuvanted virosomal H5N1 vaccine induces high frequencies of multifunctional Th1 CD4+ cells and strong antibody responses in mice
    Abdullah S Madhun
    Influenza Centre, The Gade Institute, University of Bergen, N 5021 Bergen, Norway
    Vaccine 27:7367-76. 2009
  3. doi A phase I clinical trial of a PER.C6 cell grown influenza H7 virus vaccine
    Rebecca J Cox
    Influenza Centre, The Gade Institute, University of Bergen, N 5021 Bergen, Norway
    Vaccine 27:1889-97. 2009
  4. doi Evaluation of a virosomal H5N1 vaccine formulated with Matrix M™ adjuvant in a phase I clinical trial
    Rebecca J Cox
    Influenza Centre, The Gade Institute, University of Bergen, N 5021 Bergen, Norway
    Vaccine 29:8049-59. 2011
  5. pmc The human potential of a recombinant pandemic influenza vaccine produced in tobacco plants
    Asne Jul-Larsen
    Influenza Centre, The Gade Institute, University of Bergen, Bergen, Norway
    Hum Vaccin Immunother 8:653-61. 2012
  6. doi T-helper 1 cells elicited by H5N1 vaccination predict seroprotection
    Gabriel K Pedersen
    The Gade Institute, Haukeland University Hospital, Bergen, Norway
    J Infect Dis 206:158-66. 2012
  7. doi A cell-based H7N1 split influenza virion vaccine confers protection in mouse and ferret challenge models
    Rebecca J Cox
    Influenza Centre, The Gade Institute, University of Bergen, Bergen, Norway
    Influenza Other Respir Viruses 3:107-17. 2009
  8. doi Matrix-M adjuvanted virosomal H5N1 vaccine confers protection against lethal viral challenge in a murine model
    Gabriel Pedersen
    Influenza Centre, The Gade Institute, University of Bergen, Bergen, Norway
    Influenza Other Respir Viruses 5:426-37. 2011
  9. doi Intranasal c-di-GMP-adjuvanted plant-derived H5 influenza vaccine induces multifunctional Th1 CD4+ cells and strong mucosal and systemic antibody responses in mice
    Abdullah S Madhun
    Influenza Centre, The Gade Institute, University of Bergen, N 5021 Bergen, Norway
    Vaccine 29:4973-82. 2011
  10. doi An adjuvanted pandemic influenza H1N1 vaccine provides early and long term protection in health care workers
    Abdullah S Madhun
    Influenza Centre, The Gade Institute, University of Bergen, N 5021 Bergen, Norway
    Vaccine 29:266-73. 2010

Collaborators

Detail Information

Publications10

  1. pmc Pandemic influenza vaccines - the challenges
    Lars R Haaheim
    Myrdalskogen 95, N 5117 Ulset, Norway
    Viruses 1:1089-109. 2009
    ..This review will cover some difficult vaccine questions, such as the immunological challenges, the new production platforms, and the limited supply and global equity issues...
  2. doi Intramuscular Matrix-M-adjuvanted virosomal H5N1 vaccine induces high frequencies of multifunctional Th1 CD4+ cells and strong antibody responses in mice
    Abdullah S Madhun
    Influenza Centre, The Gade Institute, University of Bergen, N 5021 Bergen, Norway
    Vaccine 27:7367-76. 2009
    ..Our results highlight that Matrix-M adjuvant is a promising parenteral adjuvant for formulating pandemic candidate vaccines...
  3. doi A phase I clinical trial of a PER.C6 cell grown influenza H7 virus vaccine
    Rebecca J Cox
    Influenza Centre, The Gade Institute, University of Bergen, N 5021 Bergen, Norway
    Vaccine 27:1889-97. 2009
    ..In conclusion, our study shows that producing effective H7 pandemic vaccines is as challenging as has been observed for H5 vaccines...
  4. doi Evaluation of a virosomal H5N1 vaccine formulated with Matrix M™ adjuvant in a phase I clinical trial
    Rebecca J Cox
    Influenza Centre, The Gade Institute, University of Bergen, N 5021 Bergen, Norway
    Vaccine 29:8049-59. 2011
    ..In conclusion, Matrix M™ adjuvant was well tolerated and augmented the antibody response allowing considerable dose sparing down to 1.5 μg HA...
  5. pmc The human potential of a recombinant pandemic influenza vaccine produced in tobacco plants
    Asne Jul-Larsen
    Influenza Centre, The Gade Institute, University of Bergen, Bergen, Norway
    Hum Vaccin Immunother 8:653-61. 2012
    ..We conclude that the tobacco derived recombinant HAC1 antigen is a promising vaccine candidate recognized by both B- and T cells...
  6. doi T-helper 1 cells elicited by H5N1 vaccination predict seroprotection
    Gabriel K Pedersen
    The Gade Institute, Haukeland University Hospital, Bergen, Norway
    J Infect Dis 206:158-66. 2012
    ..An immunological marker for H5N1 vaccine effectiveness is needed for early identification of the best vaccine candidate...
  7. doi A cell-based H7N1 split influenza virion vaccine confers protection in mouse and ferret challenge models
    Rebecca J Cox
    Influenza Centre, The Gade Institute, University of Bergen, Bergen, Norway
    Influenza Other Respir Viruses 3:107-17. 2009
    ..In recent years, several avian influenza subtypes (H5, H7 and H9) have transmitted directly from birds to man, posing a pandemic threat...
  8. doi Matrix-M adjuvanted virosomal H5N1 vaccine confers protection against lethal viral challenge in a murine model
    Gabriel Pedersen
    Influenza Centre, The Gade Institute, University of Bergen, Bergen, Norway
    Influenza Other Respir Viruses 5:426-37. 2011
    ..As regulatory authorities have not yet approved a surrogate correlate of protection for H5N1 vaccines, it is important to test the protective efficacy of candidate H5N1 vaccines in a viral challenge study...
  9. doi Intranasal c-di-GMP-adjuvanted plant-derived H5 influenza vaccine induces multifunctional Th1 CD4+ cells and strong mucosal and systemic antibody responses in mice
    Abdullah S Madhun
    Influenza Centre, The Gade Institute, University of Bergen, N 5021 Bergen, Norway
    Vaccine 29:4973-82. 2011
    ..Our results highlight that c-di-GMP is a promising mucosal adjuvant for pandemic influenza vaccine development...
  10. doi An adjuvanted pandemic influenza H1N1 vaccine provides early and long term protection in health care workers
    Abdullah S Madhun
    Influenza Centre, The Gade Institute, University of Bergen, N 5021 Bergen, Norway
    Vaccine 29:266-73. 2010
    ..A rapid induction of protective antibody is important in reducing community spread of pandemic influenza and in helping maintain the integrity of the health care system during the pandemic...