Kari T Inngjerdingen
Affiliation: University of Oslo
Inngjerdingen K, Coulibaly A, Diallo D, Michaelsen T, Paulsen B. A complement fixing polysaccharide from Biophytum petersianum Klotzsch, a medicinal plant from Mali, West Africa. Biomacromolecules. 2006;7:48-53 pubmed
..These results indicate that the pectic substance in B. petersianum contains both rhamnogalacturonan and xylogalacturonan regions. ..
Inngjerdingen K, Kiyohara H, Matsumoto T, Petersen D, Michaelsen T, Diallo D, et al
. An immunomodulating pectic polymer from Glinus oppositifolius. Phytochemistry. 2007;68:1046-58 pubmed
..A decrease in Araf units, 1,3,6-linked Galp units and a partial hydrolysed rhamnogalacturonan backbone, in addition to a reduction in molecular weight are factors that might have contributed to reduced bioactivity. ..
Zou Y, Fu Y, Chen X, Austarheim I, Inngjerdingen K, Huang C, et al
. Purification and Partial Structural Characterization of a Complement Fixating Polysaccharide from Rhizomes of Ligusticum chuanxiong. Molecules. 2017;22: pubmed publisher
..LCP-I-I exhibited potent complement fixation activity, ICH50 of 26.3 ± 2.2 µg/mL, and thus has potential as a natural immunomodulator. ..
Inngjerdingen K, Debes S, Inngjerdingen M, Hokputsa S, Harding S, Rolstad B, et al
. Bioactive pectic polysaccharides from Glinus oppositifolius (L.) Aug. DC., a Malian medicinal plant, isolation and partial characterization. J Ethnopharmacol. 2005;101:204-14 pubmed
..Both GOA1 and GOA2 were shown to exhibit potent dose-dependent complement fixating activities, and induced chemotaxis of macrophages, T cells and NK cells...
Inngjerdingen K, Patel T, Chen X, Kenne L, Allen S, Morris G, et al
. Immunological and structural properties of a pectic polymer from Glinus oppositifolius. Glycobiology. 2007;17:1299-310 pubmed
..The ability of GOA2 to induce secretion of proinflammatory cytokines was examined. Marked upregulations in mRNA for IL-1beta from rat macrophages and IFN-gamma from NK cells were found...
Tvete Inngjerdingen K, Ballo N, Zhang B, Malterud K, Michaelsen T, Diallo D, et al
. A comparison of bioactive aqueous extracts and polysaccharide fractions from roots of wild and cultivated Cochlospermum tinctorium A. Rich. Phytochemistry. 2013;93:136-43 pubmed publisher
..tinctorium contain the same types of bioactive polysaccharides as the wild roots. However, in order to utilize roots of cultivated C. tinctorium in traditional medicine the cultivation method should be improved. ..