Giang Thanh Thi Ho
Affiliation: University of Oslo
Ho G, Ahmed A, Zou Y, Aslaksen T, Wangensteen H, Barsett H. Structure-activity relationship of immunomodulating pectins from elderberries. Carbohydr Polym. 2015;125:314-22 pubmed publisher
..These results indicated that elderberries contained immunomodulating polysaccharides, where the ramified regions express the activities observed. ..
Ho G, Zou Y, Aslaksen T, Wangensteen H, Barsett H. Structural characterization of bioactive pectic polysaccharides from elderflowers (Sambuci flos). Carbohydr Polym. 2016;135:128-37 pubmed publisher
..No cytotoxity was observed. ..
Ho G, Zou Y, Wangensteen H, Barsett H. RG-I regions from elderflower pectins substituted on GalA are strong immunomodulators. Int J Biol Macromol. 2016;92:731-738 pubmed publisher
..The results showed that the high molecular RG-I containing polymers exhibit the highest dose-dependent complement fixing and macrophage stimulating activities. ..
Ho G, Kase E, Wangensteen H, Barsett H. Effect of Phenolic Compounds from Elderflowers on Glucose- and Fatty Acid Uptake in Human Myotubes and HepG2-Cells. Molecules. 2017;22: pubmed publisher
..Elderflower might therefore be valuable as a functional food against diabetes. ..
Ho G, Wangensteen H, Barsett H. Elderberry and Elderflower Extracts, Phenolic Compounds, and Metabolites and Their Effect on Complement, RAW 264.7 Macrophages and Dendritic Cells. Int J Mol Sci. 2017;18: pubmed publisher
..Only 4-methylcatechol was cytotoxic at the highest tested concentration (100 µM). Elderberry and elderflower constituents may possess inflammatory modulating activity, which increases their nutritional value. ..
Ho G, Nguyen T, Kase E, Tadesse M, Barsett H, Wangensteen H. Enhanced Glucose Uptake in Human Liver Cells and Inhibition of Carbohydrate Hydrolyzing Enzymes by Nordic Berry Extracts. Molecules. 2017;22: pubmed publisher
..These results increase the value of these berries as a component of a healthy Nordic diet and have a potential benefit against diabetes. ..