Torgils Fossen

..From bulbs of the cultivar "Tropea", 5.9 mg of taxifolin 7-glucoside and 98.1 mg of taxifolin have been isolated per kilogram of FW...

..CypA interacts with the virus proteins Capsid (CA) and Vpr, however, the mechanism through which CypA influences HIV-1 infectivity still remains unclear...

..In this study, we investigated the importance of the highly conserved serine residue at position 40, which until now has not been assigned to any known function of p6...

..St.-Hil. In pigments 2, 4 and 5 a malonyl unit is linked to the rhamnose 4-position, which has not been reported previously for any anthocyanin before. The identifications were mainly based on 2D NMR spectroscopy and electrospray MS...

..chimaera and D. cordobae (78 and 28% of the total anthocyanin content, respectively) differs from previously analysed orchid species, in which glucose is found as the only anthocyanin sugar moiety...

..The equilibria between the various forms of 1 were studied by two-dimensional NOESY and ROESY NMR spectroscopy. 2D HSQC-TOCSY NMR spectroscopy was among the methods used for characterization of the various forms...

..This stability may extend the present use of anthocyanins as nutraceuticals, pharmaceuticals or colorants...

..The binding motifs of p6 to Tsg-101, ALIX and Vpr coincide with binding regions and catalytic sites of p6 to CypA, suggesting a potential role of CypA in modulating functional interactions of HIV-1...

..Even though 1 and 2 are based on a different aglycone, their structures may be similar to tentatively identified pigments, which have been assumed to contribute to the colour of red wines...

..The ornamental autumn leaves and the characteristic purplish red bark of this variety were found to contain only pigment 5...

..The interaction of HIV-1 viral protein R (Vpr) with the human peptidyl prolyl isomerase CypA is known to occur in vitro and in vivo. However, the nature of the interaction of CypA with Pro-35 of N-terminal Vpr has remained undefined...

..The colours of 1 and 2 in buffered solutions with pH 1.1 and pH 6.9 have been described by the CIELAB coordinates h(ab) (hue angle), C* (chroma), and L* (lightness)...

..The relative order of the reducing capacity of the various 5-carboxypyranoanthocyanidin 3-glucosides and anthocyanidin 3-glucosides were nearly alike, whether determined by coulometric array detection or FRAP...

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..These pigments have been proposed to exist predominantly as hemiacetals in slightly acidic to neutral solvents, which is a relevant pH range in plants and in the human gastrointestinal tract...

..Signal duplication in the NMR spectra of 2, 4, and 5 revealed the presence of rotameric conformers, created by rotational hindrance at the C(sp3) -C(sp2) glucosyl-flavone linkage in these flavone C-glycosides...

..The stable C-glycosyl-3-deoxyanthocyanidins may thus attract interest as possible colorants in the food industry, etc...

..It is concluded that a stabilization of the sigma-complexes, assumed to be the intermediates in the reactions, takes place for the common anthocyanins (1-3) contrary to the pyranoanthocyanins (4-6)...

..These latter compounds are most probably formed by esterification of 2 with the solvent (acidified methanol) during the isolation process. The structures were elucidated by 2D NMR spectroscopy and LC-MS...

..This signature could indicate the pathological nature of viruses emerging in the future and thus aid in the recognition of these viruses...

..Its structure was determined by 1D and 2D NMR spectroscopy and high-resolution MS. To the best of our knowledge, this is the first time that a four-membered ring occurs in the side chain of protolimonoids...

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..Compared to cyanidin 3-glycosides the cyanidin 4'-glucoside derivatives showed hypsochromic shifts of visible lambda(max) and hyperchromic effects on wavelengths around 440 nm, similar to pelargonidin 3-glycosides...

..Luban, J., Neidleman, J., Greene, W. C., and Schubert, U. (2003) J. Biol. Chem. 278, 43170-43181) of a functional interaction between the major cellular isomerase cyclophilin A and Vpr, both of which are incorporated into HIV-1 virions...

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..The consequences of the strong oligomerization and helical propensities of the molecule are discussed and used to formulate a hypothetical model of its interaction with the mitochondrial membrane...

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..The individual quantities of quercetin 3-O-(2''- O-beta-apiofuranosyl-6''- O-alpha-rhamnopyranosyl-beta-glucopyranoside) and phloretin 3',5'-di-C-beta-glucopyranoside was similar to that of rutin in several cultivars...