Torgils Fossen

Summary

Affiliation: University of Bergen
Country: Norway

Publications

  1. ncbi request reprint Onions: a source of unique dietary flavonoids
    Rune Slimestad
    PlantChem, Saerheim Research Centre, N 4353 Klepp Station, Norway
    J Agric Food Chem 55:10067-80. 2007
  2. pmc The host-pathogen interaction of human cyclophilin A and HIV-1 Vpr requires specific N-terminal and novel C-terminal domains
    Sara M Ø Solbak
    Centre of Pharmacy, University of Bergen, N 5007 Bergen Norway
    BMC Struct Biol 11:49. 2011
  3. pmc Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly
    Jörg Votteler
    Institute of Virology, Friedrich Alexander University, Erlangen, Germany
    Retrovirology 8:11. 2011
  4. ncbi request reprint Covalent anthocyanin-flavone dimer from leaves of Oxalis triangularis
    Torgils Fossen
    Department of Chemistry, University of Bergen, Allegt 41, N 5007 Bergen, Norway
    Phytochemistry 68:652-62. 2007
  5. ncbi request reprint Anthocyanins from flowers of the orchids Dracula chimaera and D. cordobae
    Torgils Fossen
    Department of Chemistry, University of Bergen, Allegt 41, N 5007 Bergen, Norway
    Phytochemistry 63:783-7. 2003
  6. ncbi request reprint Acylated anthocyanins from leaves of Oxalis triangularis
    Torgils Fossen
    Department of Chemistry, University of Bergen, Norway
    Phytochemistry 66:1133-40. 2005
  7. ncbi request reprint C-glycosylanthocyanidins synthesized from C-glycosylflavones
    Orjan Bjorøy
    Department of Chemistry, University of Bergen, Allegt 41, N 5007 Bergen, Norway
    Phytochemistry 70:278-87. 2009
  8. ncbi request reprint Dimeric anthocyanins from strawberry (Fragaria ananassa) consisting of pelargonidin 3-glucoside covalently linked to four flavan-3-ols
    Torgils Fossen
    Department of Chemistry, University of Bergen, Allegt 41, N 5007 Bergen, Norway
    Phytochemistry 65:1421-8. 2004
  9. doi request reprint HIV-1 p6-Another viral interaction partner to the host cellular protein cyclophilin A
    Sara M Ø Solbak
    Department of Chemistry and Centre of Pharmacy, University of Bergen, Bergen, Norway
    Biochim Biophys Acta 1824:667-78. 2012
  10. ncbi request reprint Anthocyanin 3-galactosides from Cornus alba 'Sibirica' with glucosidation of the B-ring
    Orjan Bjorøy
    Department of Chemistry, University of Bergen, Allegt 41, 5007 Bergen, Norway
    Phytochemistry 68:640-5. 2007

Collaborators

  • Øyvind M Andersen
  • Ulrich Schubert
  • Monica Jordheim
  • George W Francis
  • Alok Sharma
  • Rune Slimestad
  • Kjersti Aaby
  • Peter Henklein
  • Victor Wray
  • Sara M Ø Solbak
  • Karsten Bruns
  • Orjan Bjorøy
  • Petra Henklein
  • Saleh Rayyan
  • Rene Röder
  • Jörg Votteler
  • Friedrich Hahn
  • Arnt J Raae
  • Ole Horvli
  • David Mitzner
  • Nicole Studtrucker
  • Oyvind M Andersen
  • Xuan Hong Thy Nguyen
  • Ole Johan Juvik
  • Bashar Amer
  • Sara Marie Øie Solbak
  • Tove R Reksten
  • Sara M Solbak
  • Uwe Tessmer
  • Dag Olav Øvstedal
  • Øyvind Halskau
  • Rebekka Niebert
  • Tove Ragna Reksten
  • Anni Vedeler
  • Sabine Hahn
  • Kerstin Schmidt
  • Norbert Bannert
  • Liane Neumann
  • Gudrun Holland
  • David E Ott
  • Manfred Nimtz
  • Pia Rauch
  • Marte I Flydal
  • Kjersti Kalberg
  • Stefan Sörgel
  • Elke Rücker
  • Bernhard Schick
  • André Eissmann
  • Frank Kirchhoff
  • Jan Munch

Detail Information

Publications30

  1. ncbi request reprint Onions: a source of unique dietary flavonoids
    Rune Slimestad
    PlantChem, Saerheim Research Centre, N 4353 Klepp Station, Norway
    J Agric Food Chem 55:10067-80. 2007
    ..From bulbs of the cultivar "Tropea", 5.9 mg of taxifolin 7-glucoside and 98.1 mg of taxifolin have been isolated per kilogram of FW...
  2. pmc The host-pathogen interaction of human cyclophilin A and HIV-1 Vpr requires specific N-terminal and novel C-terminal domains
    Sara M Ø Solbak
    Centre of Pharmacy, University of Bergen, N 5007 Bergen Norway
    BMC Struct Biol 11:49. 2011
    ..CypA interacts with the virus proteins Capsid (CA) and Vpr, however, the mechanism through which CypA influences HIV-1 infectivity still remains unclear...
  3. pmc Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly
    Jörg Votteler
    Institute of Virology, Friedrich Alexander University, Erlangen, Germany
    Retrovirology 8:11. 2011
    ..In this study, we investigated the importance of the highly conserved serine residue at position 40, which until now has not been assigned to any known function of p6...
  4. ncbi request reprint Covalent anthocyanin-flavone dimer from leaves of Oxalis triangularis
    Torgils Fossen
    Department of Chemistry, University of Bergen, Allegt 41, N 5007 Bergen, Norway
    Phytochemistry 68:652-62. 2007
    ..The equilibria between the various forms of 1 were studied by two-dimensional NOESY and ROESY NMR spectroscopy. 2D HSQC-TOCSY NMR spectroscopy was among the methods used for characterization of the various forms...
  5. ncbi request reprint Anthocyanins from flowers of the orchids Dracula chimaera and D. cordobae
    Torgils Fossen
    Department of Chemistry, University of Bergen, Allegt 41, N 5007 Bergen, Norway
    Phytochemistry 63:783-7. 2003
    ..chimaera and D. cordobae (78 and 28% of the total anthocyanin content, respectively) differs from previously analysed orchid species, in which glucose is found as the only anthocyanin sugar moiety...
  6. ncbi request reprint Acylated anthocyanins from leaves of Oxalis triangularis
    Torgils Fossen
    Department of Chemistry, University of Bergen, Norway
    Phytochemistry 66:1133-40. 2005
    ..St.-Hil. In pigments 2, 4 and 5 a malonyl unit is linked to the rhamnose 4-position, which has not been reported previously for any anthocyanin before. The identifications were mainly based on 2D NMR spectroscopy and electrospray MS...
  7. ncbi request reprint C-glycosylanthocyanidins synthesized from C-glycosylflavones
    Orjan Bjorøy
    Department of Chemistry, University of Bergen, Allegt 41, N 5007 Bergen, Norway
    Phytochemistry 70:278-87. 2009
    ..This stability may extend the present use of anthocyanins as nutraceuticals, pharmaceuticals or colorants...
  8. ncbi request reprint Dimeric anthocyanins from strawberry (Fragaria ananassa) consisting of pelargonidin 3-glucoside covalently linked to four flavan-3-ols
    Torgils Fossen
    Department of Chemistry, University of Bergen, Allegt 41, N 5007 Bergen, Norway
    Phytochemistry 65:1421-8. 2004
    ..Even though 1 and 2 are based on a different aglycone, their structures may be similar to tentatively identified pigments, which have been assumed to contribute to the colour of red wines...
  9. doi request reprint HIV-1 p6-Another viral interaction partner to the host cellular protein cyclophilin A
    Sara M Ø Solbak
    Department of Chemistry and Centre of Pharmacy, University of Bergen, Bergen, Norway
    Biochim Biophys Acta 1824:667-78. 2012
    ..The binding motifs of p6 to Tsg-101, ALIX and Vpr coincide with binding regions and catalytic sites of p6 to CypA, suggesting a potential role of CypA in modulating functional interactions of HIV-1...
  10. ncbi request reprint Anthocyanin 3-galactosides from Cornus alba 'Sibirica' with glucosidation of the B-ring
    Orjan Bjorøy
    Department of Chemistry, University of Bergen, Allegt 41, 5007 Bergen, Norway
    Phytochemistry 68:640-5. 2007
    ..The ornamental autumn leaves and the characteristic purplish red bark of this variety were found to contain only pigment 5...
  11. ncbi request reprint Anthocyanins with 4'-glucosidation from red onion, Allium cepa
    Torgils Fossen
    Department of Chemistry, University of Bergen, Allegt 41, N 5007, Bergen, Norway
    Phytochemistry 64:1367-74. 2003
    ..Compared to cyanidin 3-glycosides the cyanidin 4'-glucoside derivatives showed hypsochromic shifts of visible lambda(max) and hyperchromic effects on wavelengths around 440 nm, similar to pelargonidin 3-glycosides...
  12. pmc The intriguing cyclophilin A-HIV-1 Vpr interaction: prolyl cis/trans isomerisation catalysis and specific binding
    Sara M Solbak
    Department of Chemistry, University of Bergen, N 5007 Bergen, Norway
    BMC Struct Biol 10:31. 2010
    ..The interaction of HIV-1 viral protein R (Vpr) with the human peptidyl prolyl isomerase CypA is known to occur in vitro and in vivo. However, the nature of the interaction of CypA with Pro-35 of N-terminal Vpr has remained undefined...
  13. ncbi request reprint Molar absorptivities and reducing capacity of pyranoanthocyanins and other anthocyanins
    Monica Jordheim
    Department of Chemistry, University of Bergen, Norway
    J Agric Food Chem 55:10591-8. 2007
    ..The relative order of the reducing capacity of the various 5-carboxypyranoanthocyanidin 3-glucosides and anthocyanidin 3-glucosides were nearly alike, whether determined by coulometric array detection or FRAP...
  14. ncbi request reprint Anthocyanin from strawberry (Fragaria ananassa) with the novel aglycone, 5-carboxypyranopelargonidin
    Øyvind M Andersen
    Department of Chemistry, University of Bergen, Allegt 41, N 5007 Bergen, Norway
    Phytochemistry 65:405-10. 2004
    ..The colours of 1 and 2 in buffered solutions with pH 1.1 and pH 6.9 have been described by the CIELAB coordinates h(ab) (hue angle), C* (chroma), and L* (lightness)...
  15. ncbi request reprint Flavone C-glycosides from seeds of fenugreek, Trigonella foenum-graecum L
    Saleh Rayyan
    Department of Chemistry, University of Bergen, Allegt 41, Bergen, Norway
    J Agric Food Chem 58:7211-7. 2010
    ....
  16. ncbi request reprint Characterization of hemiacetal forms of anthocyanidin 3-O-beta-glycopyranosides
    Monica Jordheim
    Department of Chemistry, University of Bergen, Allegt 41, 5007 Bergen, Norway
    J Agric Food Chem 54:9340-6. 2006
    ..These pigments have been proposed to exist predominantly as hemiacetals in slightly acidic to neutral solvents, which is a relevant pH range in plants and in the human gastrointestinal tract...
  17. ncbi request reprint Flavone C-glycosides from leaves of Oxalis triangularis
    Saleh Rayyan
    Department of Chemistry, University of Bergen, Allegt 41, N 5007 Bergen, Norway
    J Agric Food Chem 53:10057-60. 2005
    ..Signal duplication in the NMR spectra of 2, 4, and 5 revealed the presence of rotameric conformers, created by rotational hindrance at the C(sp3) -C(sp2) glucosyl-flavone linkage in these flavone C-glycosides...
  18. ncbi request reprint Reactivity of anthocyanins and pyranoanthocyanins. Studies on aromatic hydrogen-deuterium exchange reactions in methanol
    Monica Jordheim
    Department of Chemistry, University of Bergen, Allegt 41, 5007, Bergen, Norway
    J Agric Food Chem 55:8261-8. 2007
    ..It is concluded that a stabilization of the sigma-complexes, assumed to be the intermediates in the reactions, takes place for the common anthocyanins (1-3) contrary to the pyranoanthocyanins (4-6)...
  19. doi request reprint Structural properties of anthocyanins: rearrangement of C-glycosyl-3-deoxyanthocyanidins in acidic aqueous solutions
    Orjan Bjorøy
    Department of Chemistry, University of Bergen, Allegt 41, N 5007 Bergen, Norway
    J Agric Food Chem 57:6668-77. 2009
    ..The stable C-glycosyl-3-deoxyanthocyanidins may thus attract interest as possible colorants in the food industry, etc...
  20. doi request reprint Novel GHB-derived natural products from European mistletoe (Viscum album)
    Bashar Amer
    Department of Chemistry and Centre for Pharmacy, University of Bergen, Allégt, Bergen, Norway
    Pharm Biol 51:981-6. 2013
    ..At present the most important application of mistletoe extracts is in the treatment of cancer. However, natural products specific to mistletoe have rarely been encountered in the current literature...
  21. ncbi request reprint 6-carboxydihydroresveratrol 3-O-β-glucopyranoside--a novel natural product from the Cretaceous relict Metasequoia glyptostroboides
    Xuan Hong Thy Nguyen
    Department of Chemistry and Centre for Pharmacy, University of Bergen, Allegt 41, N 5007 Bergen, Norway
    Fitoterapia 95:109-14. 2014
    ..glyptostroboides, including the novel natural product 6-carboxydihydroresveratrol 3-O-β-glucopyranoside. The structure determinations were based on extensive use of 2D NMR spectroscopic techniques and high-resolution mass spectrometry. ..
  22. doi request reprint Influenza A virus protein PB1-F2 from different strains shows distinct structural signatures
    Sara M Ø Solbak
    Department of Chemistry and Centre of Pharmacy, University of Bergen, N 5007 Bergen, Norway
    Biochim Biophys Acta 1834:568-82. 2013
    ..This signature could indicate the pathological nature of viruses emerging in the future and thus aid in the recognition of these viruses...
  23. doi request reprint A new protolimonoid from Capuronianthus mahafalensis
    Torgils Fossen
    Centre for Pharmacy and Department of Chemistry, University of Bergen, Bergen, Norway
    Fitoterapia 83:901-6. 2012
    ..Its structure was determined by 1D and 2D NMR spectroscopy and high-resolution MS. To the best of our knowledge, this is the first time that a four-membered ring occurs in the side chain of protolimonoids...
  24. ncbi request reprint Anthocyanins from red onion, Allium cepa, with novel aglycone
    Torgils Fossen
    Department of Chemistry, University of Bergen, Allegt 41, N 5007 Bergen, Norway
    Phytochemistry 62:1217-20. 2003
    ..These latter compounds are most probably formed by esterification of 2 with the solvent (acidified methanol) during the isolation process. The structures were elucidated by 2D NMR spectroscopy and LC-MS...
  25. doi request reprint HIV-1 p6 - a structured to flexible multifunctional membrane-interacting protein
    Sara Marie Øie Solbak
    Department of Chemistry and Centre for Pharmacy, University of Bergen, N 5007 Bergen, Norway
    Biochim Biophys Acta 1828:816-23. 2013
    ....
  26. doi request reprint The flavonoids of tomatoes
    Rune Slimestad
    Saerheim Research Centre, PlantChem, N 4353 Klepp Station, Norway
    J Agric Food Chem 56:2436-41. 2008
    ..The individual quantities of quercetin 3-O-(2''- O-beta-apiofuranosyl-6''- O-alpha-rhamnopyranosyl-beta-glucopyranoside) and phloretin 3',5'-di-C-beta-glucopyranoside was similar to that of rutin in several cultivars...
  27. pmc Proline 35 of human immunodeficiency virus type 1 (HIV-1) Vpr regulates the integrity of the N-terminal helix and the incorporation of Vpr into virus particles and supports the replication of R5-tropic HIV-1 in human lymphoid tissue ex vivo
    Jörg Votteler
    Institute of Virology, University of Erlangen Nuremberg, Erlangen, Germany
    J Virol 81:9572-6. 2007
    ....
  28. ncbi request reprint Structural characterization and oligomerization of PB1-F2, a proapoptotic influenza A virus protein
    Karsten Bruns
    Institute of Clinical and Molecular Virology, University of Erlangen Nurnberg, Erlangen D 91054, Germany
    J Biol Chem 282:353-63. 2007
    ..The consequences of the strong oligomerization and helical propensities of the molecule are discussed and used to formulate a hypothetical model of its interaction with the mitochondrial membrane...
  29. ncbi request reprint Solution structure of the human immunodeficiency virus type 1 p6 protein
    Torgils Fossen
    Department of Structural Biology, Gesellschaft fur Biotechnologische Forschung, D 38124 Braunschweig, Germany
    J Biol Chem 280:42515-27. 2005
    ....
  30. ncbi request reprint Structural characterization of the HIV-1 Vpr N terminus: evidence of cis/trans-proline isomerism
    Karsten Bruns
    Department of Structural Biology, Gesellschaft fur Biotechnologische Forschung, D 38124 Braunschweig, Germany
    J Biol Chem 278:43188-201. 2003
    ..Luban, J., Neidleman, J., Greene, W. C., and Schubert, U. (2003) J. Biol. Chem. 278, 43170-43181) of a functional interaction between the major cellular isomerase cyclophilin A and Vpr, both of which are incorporated into HIV-1 virions...