S D Fossa

Summary

Affiliation: University of Oslo
Country: Norway

Publications

  1. pmc Association between long-term neuro-toxicities in testicular cancer survivors and polymorphisms in glutathione-s-transferase-P1 and -M1, a retrospective cross sectional study
    Jan Oldenburg
    Department of Clinical Cancer Research, The Norwegian Radiumhospital, Oslo, Norway
    J Transl Med 5:70. 2007
  2. ncbi request reprint Quality of life of patients with newly diagnosed poor prognosis M1 prostate cancer undergoing orchiectomy without or with mitomycin C. Results from the EORTC Phase-III trial 30893
    S D Fossa
    Department of Medical Oncology and Radiotherapy, Norwegian Radium Hospital, Oslo, Norway
    Eur Urol 37:541-51. 2000
  3. ncbi request reprint Health-related quality of life in patients treated for testicular cancer
    S D Fossa
    Department of Medical Oncology and Radiotherapy, Norwegian Radium Hospital, Oslo, Norway
    Curr Opin Urol 9:425-9. 1999
  4. ncbi request reprint Flutamide versus prednisone in patients with prostate cancer symptomatically progressing after androgen-ablative therapy: a phase III study of the European organization for research and treatment of cancer genitourinary group
    S D Fossa
    Department of Medical Oncology and Radiotherapy, Norwegian Radium Hospital, Oslo, Norway
    J Clin Oncol 19:62-71. 2001
  5. ncbi request reprint Short Form 36 and Hospital Anxiety and Depression Scale. A comparison based on patients with testicular cancer
    S D Fossa
    Department of Medical Oncology and Radiotherapy, The Norwegian Radium Hospital, University of Oslo, Montebello, 0310, Oslo, Norway
    J Psychosom Res 52:79-87. 2002
  6. ncbi request reprint Long-term renal function after treatment for malignant germ-cell tumours
    S D Fossa
    Department of Medical Oncology and Radiotherapy, The Norwegian Radium Hospital, Oslo
    Ann Oncol 13:222-8. 2002
  7. ncbi request reprint No randomised trial of prostate-cancer screening in Norway
    S D Fossa
    Norwegian Radium Hospital, Oslo
    Lancet Oncol 2:741-5; discussion 746-9. 2001
  8. ncbi request reprint Selection of patients may limit the generalizability of results from cancer trials
    Sophie D Fossa
    Norwegian Radium Hospital, University of Oslo
    Acta Oncol 41:131-7. 2002
  9. ncbi request reprint Quality of life in good prognosis patients with metastatic germ cell cancer: a prospective study of the European Organization for Research and Treatment of Cancer Genitourinary Group/Medical Research Council Testicular Cancer Study Group (30941/TE20)
    Sophie D Fossa
    Norwegian Radium Hospital, Oslo, Norway
    J Clin Oncol 21:1107-18. 2003
  10. ncbi request reprint Fatigue, anxiety, and depression in long-term survivors of testicular cancer
    Sophie D Fossa
    Norwegian Radium Hospital, Department of Oncology and Radiotherapy, Oslo, Norway
    J Clin Oncol 21:1249-54. 2003

Detail Information

Publications83

  1. pmc Association between long-term neuro-toxicities in testicular cancer survivors and polymorphisms in glutathione-s-transferase-P1 and -M1, a retrospective cross sectional study
    Jan Oldenburg
    Department of Clinical Cancer Research, The Norwegian Radiumhospital, Oslo, Norway
    J Transl Med 5:70. 2007
    ..To assess the impact of polymorphisms in Glutathione S-transferase (GST) -P1, -M1, and -T1 on self-reported chemotherapy-induced long-term toxicities in testicular cancer survivors (TCSs)...
  2. ncbi request reprint Quality of life of patients with newly diagnosed poor prognosis M1 prostate cancer undergoing orchiectomy without or with mitomycin C. Results from the EORTC Phase-III trial 30893
    S D Fossa
    Department of Medical Oncology and Radiotherapy, Norwegian Radium Hospital, Oslo, Norway
    Eur Urol 37:541-51. 2000
    ..To compare the quality of life (QL) of patients with poor prognosis M1 prostate cancer treated with orchiectomy alone (ORCH) or orchiectomy combined with adjuvant mitomycin C (MMC; 15 mg/m(2) i.v. q 6 weeks: ORCH+MMC; EORTC trial 30893)...
  3. ncbi request reprint Health-related quality of life in patients treated for testicular cancer
    S D Fossa
    Department of Medical Oncology and Radiotherapy, Norwegian Radium Hospital, Oslo, Norway
    Curr Opin Urol 9:425-9. 1999
    ..The long-term investigation and follow-up of testicular cancer survivors provide useful information on survivorship problems in cured cancer patients in general...
  4. ncbi request reprint Flutamide versus prednisone in patients with prostate cancer symptomatically progressing after androgen-ablative therapy: a phase III study of the European organization for research and treatment of cancer genitourinary group
    S D Fossa
    Department of Medical Oncology and Radiotherapy, Norwegian Radium Hospital, Oslo, Norway
    J Clin Oncol 19:62-71. 2001
    ....
  5. ncbi request reprint Short Form 36 and Hospital Anxiety and Depression Scale. A comparison based on patients with testicular cancer
    S D Fossa
    Department of Medical Oncology and Radiotherapy, The Norwegian Radium Hospital, University of Oslo, Montebello, 0310, Oslo, Norway
    J Psychosom Res 52:79-87. 2002
    ....
  6. ncbi request reprint Long-term renal function after treatment for malignant germ-cell tumours
    S D Fossa
    Department of Medical Oncology and Radiotherapy, The Norwegian Radium Hospital, Oslo
    Ann Oncol 13:222-8. 2002
    ....
  7. ncbi request reprint No randomised trial of prostate-cancer screening in Norway
    S D Fossa
    Norwegian Radium Hospital, Oslo
    Lancet Oncol 2:741-5; discussion 746-9. 2001
    ..In this review, the NUCG's reasons for not participating in the trial are discussed in full...
  8. ncbi request reprint Selection of patients may limit the generalizability of results from cancer trials
    Sophie D Fossa
    Norwegian Radium Hospital, University of Oslo
    Acta Oncol 41:131-7. 2002
    ..By registering patients undergoing comparable treatment outside a trial, the overall applicability of the treatment in question can be assessed...
  9. ncbi request reprint Quality of life in good prognosis patients with metastatic germ cell cancer: a prospective study of the European Organization for Research and Treatment of Cancer Genitourinary Group/Medical Research Council Testicular Cancer Study Group (30941/TE20)
    Sophie D Fossa
    Norwegian Radium Hospital, Oslo, Norway
    J Clin Oncol 21:1107-18. 2003
    ..To describe global quality of life (GLQL) in patients with metastatic testicular cancer (TC) treated with four different schedules of bleomycin, etoposide, and cisplatin (BEP) chemotherapy (four v three cycles given over 5 v 3 days)...
  10. ncbi request reprint Fatigue, anxiety, and depression in long-term survivors of testicular cancer
    Sophie D Fossa
    Norwegian Radium Hospital, Department of Oncology and Radiotherapy, Oslo, Norway
    J Clin Oncol 21:1249-54. 2003
    ..Occurrence of CF in TCSs is compared with findings in male survivors of Hodgkin's disease (HDSs) and in males from the general population (GenPop)...
  11. ncbi request reprint Definitive radiotherapy of prostate cancer: the possible role of staging lymphadenectomy
    Sophie D Fossa
    Department of Clinical Research, The Norwegian Radium Hospital, Oslo, Norway
    Int J Radiat Oncol Biol Phys 57:33-41. 2003
    ..To evaluate the postradiotherapy 5-year cancer-specific (CSS), clinical progression-free (cPFS), and overall (OS) survival rates in patients with pN0 M0 prostate cancer (PC)...
  12. ncbi request reprint [Long-term effects after mantle field radiotherapy for Hodgkin's lymphoma]
    Sophie D Fossa
    Det norske radiumhospital HF, Montebello, 0310 Oslo
    Tidsskr Nor Laegeforen 125:41-4. 2005
    ..Cancer survivors have an increased risk of life-long health problems that may be associated with their treatment...
  13. ncbi request reprint Interferon-alpha-2a with or without 13-cis retinoic acid in patients with progressive, measurable metastatic renal cell carcinoma
    Sophie D Fossa
    Department of Oncology, The Norwegian Radium Hospital, Oslo, Norway
    Cancer 101:533-40. 2004
    ..In 1995, preclinical and clinical data indicated an improvement of these results if IFN was combined with 13-cis retinoic acid (CRA)...
  14. ncbi request reprint Long-term sequelae after cancer therapy--survivorship after treatment for testicular cancer
    Sophie D Fossa
    Norwegian Radium Hospital, Department of Clinical Cancer Research, Montebello, Oslo, Norway
    Acta Oncol 43:134-41. 2004
    ..Knowledge of post-treatment long-term morbidity is essential for early recognition and treatment of late complications, and enables adequate counselling of new cancer patients...
  15. ncbi request reprint [Are all LH-RH analogues equally effective in prostate cancer?]
    Sophie D Fossa
    Fagområdet Klinisk kreftforskning, Enhet for langtidsstudier, Rikshospitalet Radiumhospitalet, 0310 Oslo
    Tidsskr Nor Laegeforen 125:2493-5. 2005
    ..Gonadotropin analogues are used in patients with prostate cancer for Leydig cell suppression with serum testosterone levels within the range after castration. Insufficient effect may have adverse consequences on the clinical course...
  16. pmc Increased mortality rates in young and middle-aged patients with malignant germ cell tumours
    S D Fossa
    The Norwegian Radium Hospital, Department of Clinical Research, Montebello, N 0310 Oslo, Norway
    Br J Cancer 90:607-12. 2004
    ..The increased death risk due to benign gastrointestinal disorders, probably related to radiotherapy, requires future in-depth analysis...
  17. pmc Intensive induction chemotherapy with C-BOP/BEP for intermediate- and poor-risk metastatic germ cell tumours (EORTC trial 30948)
    S D Fossa
    Department of Oncology, Norwegian Radium Hospital, University of Oslo, Oslo, Norway
    Br J Cancer 93:1209-14. 2005
    ..The treatment's toxicity is manageable in a multicentre setting. In poor prognosis patients, C-BOP/BEP should be compared to standard chemotherapy of four cycles of BEP...
  18. ncbi request reprint Testicular carcinoma in situ in patients with extragonadal germ-cell tumours: the clinical role of pretreatment biopsy
    S D Fossa
    Department of Clinical Research, The Norwegian Radium Hospital, Oslo, Norway
    Ann Oncol 14:1412-8. 2003
    ....
  19. ncbi request reprint Liposomal doxorubicin (Caelyx) in symptomatic androgen-independent prostate cancer (AIPC)--delayed response and flare phenomenon should be considered
    Sophie D Fossa
    Department of Medical Oncology and Radiotherapy, The Norwegian Radium Hospital, Montebello, Oslo
    Scand J Urol Nephrol 36:34-9. 2002
    ..The formulation may therefore be beneficial in anthracycline-sensitive malignancies, where toxicity represents a major problem, as is the case in androgen-insensitive prostate cancer (AIPC)...
  20. doi request reprint Predicted cardiovascular mortality and reported cardiovascular morbidity in testicular cancer survivors
    H S Haugnes
    Department of Oncology, Institute of Clinical Medicine, University of Tromsø, Tromsø, Norway
    J Cancer Surviv 2:128-37. 2008
    ....
  21. ncbi request reprint Oral mucosal side effects of cytotoxic chemotherapy of testicular cancer. A retrospective study
    B B Herlofson
    Department of Oral Surgery and Oral Medicine, Faculty of Dentistry, University of Oslo, Norway
    Eur J Oral Sci 105:523-6. 1997
    ..The study revealed that 62% of the patients in the chemotherapy group developed adverse soft tissue reactions, with mucositis and pain as chief complaints, whereas none in the control group experienced any mucosal complications...
  22. ncbi request reprint Optimal planning target volume for stage I testicular seminoma: A Medical Research Council randomized trial. Medical Research Council Testicular Tumor Working Group
    S D Fossa
    Norwegian Radium Hospital, Oslo, Norway
    J Clin Oncol 17:1146. 1999
    ..To compare relapse rates and toxicity associated with para-aortic (PA) strip or PA and ipsilateral iliac lymph node irradiation (dogleg [DL] field) (30 Gy/15 fractions/3 weeks) for stage I testicular seminoma...
  23. pmc How safe is surveillance in patients with histologically low-risk non-seminomatous testicular cancer in a geographically extended country with limited computerised tomographic resources?
    S D Fossa
    Department of Medical Oncology, Norwegian Radium Hospital, Oslo
    Br J Cancer 70:1156-60. 1994
    ..The responsible cancer centre and the local hospitals should establish a high degree of cooperation and enable adequate follow-up examinations in these patients...
  24. pmc Risk of cancer in relatives of testicular cancer patients
    K Heimdal
    Department of Genetics, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway
    Br J Cancer 73:970-3. 1996
    ..This study supports the hypothesis that families of testicular cancer patients are not prone to cancer...
  25. doi request reprint Health status at long-term follow-up in patients treated for extremity localized Ewing Sarcoma or osteosarcoma: a Scandinavian sarcoma group study
    L H Aksnes
    Department of Oncology, The Norwegian Radium Hospital, Rikshospitalet University Hospital, Oslo, Norway
    Pediatr Blood Cancer 53:84-9. 2009
    ..The results were compared with findings in age- and gender-matched individuals from the general population (NORMs)...
  26. ncbi request reprint Prognostic value of neuroendocrine serum markers and PSA in irradiated patients with pN0 localized prostate cancer
    W Lilleby
    Department of Oncology and Radiotherapy, Norwegian Radium Hospital, N 0310 Oslo, Norway
    Prostate 46:126-33. 2001
    ..We evaluated the additional prognostic impact of serum levels of neuron-specific enolase (NSE) and chromograninA (CgA) after curative radiotherapy and the importance of serum PSA, analyzed 3 months after irradiation...
  27. pmc The prognostic significance of prostate specific antigen in metastatic hormone-resistant prostate cancer
    S D Fossa
    Department of Medical Oncology, Norwegian Radium Hospital, Oslo
    Br J Cancer 66:181-4. 1992
    ..The lack of serum PSA to predict survival may be explained by a heterogenous composition of hormone resistant prostate cancer as regards differentiated and/or PSA producing vs undifferentiated and/or PSA non-producing cells...
  28. doi request reprint Malignant ovarian germ cell tumors: presentation, survival and second cancer in a population based Norwegian cohort (1953-2009)
    O Solheim
    Department of Gynaecologic Oncology, Oslo University Hospital, The Norwegian Radium Hospital, Oslo, Norway National Resource Centre for Late Effects after Cancer Treatment, Oslo University Hospital, The Norwegian Radium Hospital, Oslo, Norway Electronic address
    Gynecol Oncol 131:330-5. 2013
    ....
  29. ncbi request reprint Treatment-related premature ovarian failure as a long-term complication after Hodgkin's lymphoma
    U K H Haukvik
    University of Oslo, Norway
    Ann Oncol 17:1428-33. 2006
    ..The scope of this study was to investigate the risk of developing POF as a long-term complication in young women treated for Hodgkin's lymphoma...
  30. ncbi request reprint Expression of c-erbB-2 protein, neuron-specific enolase and DNA flow cytometry in locally advanced transitional cell carcinoma of the urinary bladder
    A Berner
    Department of Pathology, Norwegian Radium Hospital, Oslo
    Histopathology 22:327-33. 1993
    ..004). Whether the c-erbB-2 expression is a useful prognostic marker in addition to other conventional parameters, remains to be shown...
  31. doi request reprint Alterations of gene expression in blood cells associated with chronic fatigue in breast cancer survivors
    H Landmark-Høyvik
    Department of Genetics, Institute for Cancer Research, Norwegian Radium Hospital, Oslo University Hospital, Oslo 310, Norway
    Pharmacogenomics J 9:333-40. 2009
    ....
  32. doi request reprint Interest and preferences for exercise counselling and programming among Norwegian cancer survivors
    G M Gjerset
    Department of Clinical Cancer Research, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway
    Eur J Cancer Care (Engl) 20:96-105. 2011
    ..The knowledge from this study can contribute to make suitable physical rehabilitation available to cancer patients in the future...
  33. pmc Valvular dysfunction and left ventricular changes in Hodgkin's lymphoma survivors. A longitudinal study
    T Wethal
    Department of Cardiology, University of Oslo, Sognsvannsveien 20, Oslo 0027, Norway
    Br J Cancer 101:575-81. 2009
    ..This study examined the time-dependent development and evolution of valvular and myocardial function related to treatment with mediastinal radiotherapy and anthracyclines in HLSs...
  34. pmc Gonadal function in male patients after treatment for malignant lymphomas, with emphasis on chemotherapy
    C E Kiserud
    Department of Clinical Cancer Research, National Resource Center for long term effects after Cancer, Norwegian Radium Hospital, Rikshospitalet University Hospital, Oslo 0310, Norway
    Br J Cancer 100:455-63. 2009
    ....
  35. ncbi request reprint Components of the metabolic syndrome in long-term survivors of testicular cancer
    H S Haugnes
    Department of Oncology, Institute of Clinical Medicine, University of Tromsø, Norway
    Ann Oncol 18:241-8. 2007
    ..A possible explanation of the excess cardiovascular risk in testicular cancer (TC) survivors is development of metabolic syndrome. The association between metabolic syndrome and TC treatment is examined in long-term survivors...
  36. doi request reprint Variations in testosterone pathway genes and susceptibility to testicular cancer in Norwegian men
    W Kristiansen
    Faculty of Health Sciences, Oslo and Akershus University College of Applied Sciences, Oslo, Norway
    Int J Androl 35:819-27. 2012
    ..No statistically significant difference between the histological subtypes seminoma and non-seminoma was observed. Our results may suggest a possible association between genetic variation in the LHR gene and the risk of developing TC...
  37. ncbi request reprint Filgrastim during combination chemotherapy of patients with poor-prognosis metastatic germ cell malignancy. European Organization for Research and Treatment of Cancer, Genito-Urinary Group, and the Medical Research Council Testicular Cancer Working Party,
    S D Fossa
    Department of Medical Oncology and Radiotherapy, Norwegian Radium Hospital, Oslo
    J Clin Oncol 16:716-24. 1998
    ..To determine the effect of r-metHu granulocyte colony-stimulating factor (G-CSF) on the proportion of patients with metastatic poor-prognosis malignant germ cell tumors who receive full dose-intensity combination chemotherapy...
  38. doi request reprint C-reactive protein; a potential marker of second cancer and cardiovascular disease in testicular cancer survivors?
    T Wethal
    Department of Cardiology, Faculty Division Rikshospitalet, University of Oslo, Oslo, Norway
    Eur J Cancer 46:3425-33. 2010
    ..There is conflicting evidence regarding CRP as a marker of future cancer. We studied whether CRP predicts CVD and consecutive cancer in testicular cancer survivors (TCSs)...
  39. ncbi request reprint Parenthood probability and pregnancy outcome in patients with a cancer diagnosis during adolescence and young adulthood
    H Magelssen
    Rikshospitalet Radiumhospitalet Medical Center, Department of Clinical Cancer Research, University of Oslo, Montebello, 0310 Oslo, Norway
    Hum Reprod 23:178-86. 2008
    ..To compare first-time parenthood probability and pregnancy outcome between cancer patients and the general population...
  40. ncbi request reprint Quality of life in patients with urinary diversion after operation for locally advanced rectal cancer
    M G Guren
    Department of Clinical Cancer Research, The Norwegian Radium Hospital, N 0310 Oslo, Norway
    Eur J Surg Oncol 27:645-51. 2001
    ..The aim was to assess the quality of life (QoL) in disease-free patients with urinary diversion after extensive surgery for advanced rectal cancer...
  41. ncbi request reprint Treatment-related differences in cardiovascular risk factors in long-term survivors of testicular cancer
    T Wethal
    Department of Cardiology, Faculty Division Rikshospitalet, University of Oslo, Oslo, Norway
    J Cancer Surviv 1:8-16. 2007
    ..Treatment in testicular cancer survivors (TCSs) may be followed by cardiovascular disorders. We have examined whether today's three treatment modalities are associated with a biochemical cardiovascular risk profile...
  42. doi request reprint Genetic variation in AKT1, PTEN and the 8q24 locus, and the risk of testicular germ cell tumor
    K E Andreassen
    Department of Oncology, Oslo University Hospital, P O Box 4950, Nydalen, Oslo NO 0434, Norway
    Hum Reprod 28:1995-2002. 2013
    ..Is there an association between testicular germ cell tumor (TGCT) and genetic polymorphisms in AKT1, PTEN and the 8q24 locus?..
  43. pmc Clinical significance of DNA ploidy and S-phase fraction and their relation to p53 protein, c-erbB-2 protein and HCG in operable muscle-invasive bladder cancer
    S D Fossa
    Department of Medical Oncology and Radiotherapy, Norwegian Radium Hospital, Oslo
    Br J Cancer 68:572-8. 1993
    ..A high SPF, determined by FCM, may be helpful to identify patients with chemotherapy-sensitive TCC of the urinary bladder...
  44. ncbi request reprint Prediction of objective response to recombinant interferon-alpha with or without vinblastine in metastatic renal cell carcinoma
    S D Fossa
    Department of Medical Oncology, Norwegian Radium Hospital, Oslo
    Acta Oncol 29:303-6. 1990
    ..If at least 30% tumour size reduction is observed at that time, the patient will most probably respond objectively. If the size reduction is less, IFN with or without VB is likely to be ineffective in terms of response achievement...
  45. ncbi request reprint Lack of gonadal protection by medroxyprogesterone acetate-induced transient medical castration during chemotherapy for testicular cancer
    S D Fossa
    Department of Medical Oncology and Radiotherapy, Norwegian Radium Hospital, Oslo
    Br J Urol 62:449-53. 1988
    ....
  46. ncbi request reprint Frequent loss of 11p13 and 11p15 loci in male germ cell tumours
    R A Lothe
    Department of Genetics, Norwegian Radium Hospital, Montebello, Oslo
    Genes Chromosomes Cancer 7:96-101. 1993
    ..In addition, identification of the parental origin of the allelic losses revealed a paternal loss in six patients and a maternal loss in one case...
  47. doi request reprint Pain after palliative radiotherapy for spine metastases
    O Zaikova
    Department of Orthopaedic Surgery, Norwegian Radium Hospital, Oslo University Hospital, Montebello, Norway
    Clin Oncol (R Coll Radiol) 22:828-36. 2010
    ..The purpose of the study was to evaluate the response to palliative radiotherapy in patients with painful spinal metastatic disease (SMD)...
  48. ncbi request reprint Survival after curative treatment of muscle-invasive bladder cancer
    S D Fossa
    Department of Medical Oncology and Radiotherapy, The Norwegian Radium Hospital, Montebello, Oslo
    Acta Oncol 35:59-65. 1996
    ..However, subgroups of patients may benefit from this approach allowing bladder conservation in selected cases. More effective adjuvant regimens have to be developed for high-risk patients (pT3b/pN+)...
  49. ncbi request reprint Cardiorespiratory fitness in relation to self-reported physical function in cancer patients after chemotherapy
    L Thorsen
    Department of Psychosocial Oncology and Rehabilitation, The Norwegian Radium Hospital, Oslo, Norway
    J Sports Med Phys Fitness 46:122-7. 2006
    ..We hypothesized an association between these parameters, since they might be thought to measure parts of the same phenomenon...
  50. ncbi request reprint Blood pressure and body mass index in long-term survivors of testicular cancer
    H Sagstuen
    Department of Oncology, Institute of Clinical Medicine, University of Tromsø, N 9037 Tromsø, Norway
    J Clin Oncol 23:4980-90. 2005
    ..To evaluate blood pressure and body mass index (BMI) in long-term survivors of testicular cancer (TC) treated with different modalities...
  51. doi request reprint Fatigue in hormone-naïve prostate cancer patients treated with radical prostatectomy or definitive radiotherapy
    A E Kyrdalen
    Department of Clinical Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Rikshospitalet, Oslo, Norway
    Prostate Cancer Prostatic Dis 13:144-50. 2010
    ..Further studies of CF in prostate cancer survivors should take into consideration the survivors' pretreatment medical and psychosocial situation...
  52. ncbi request reprint Erroneous diagnosis of pancreatic cancer after radiotherapy of testicular cancer
    E Stensvold
    Department of Medical Oncology, The Norwegian Radium Hospital, Oslo, Norway
    Eur J Surg Oncol 30:352-5. 2004
    ..After radiotherapy with or without chemotherapy radiation-induced normal tissue alteration may mimic cancer and may cause major morbidity...
  53. ncbi request reprint p53, p21 and mdm2 expression vs the response to radiotherapy in transitional cell carcinoma of the bladder
    R Røtterud
    Department of Pathology, The Norwegian Radium Hospital, Montebello N 0310, Norway
    BJU Int 88:202-8. 2001
    ..To identify, in a retrospective study, possible molecular markers predictive of radioresponsiveness in patients with transitional cell carcinoma (TCC) of the bladder...
  54. pmc Cisplatin, vincristine and ifosphamide combination chemotherapy of metastatic seminoma: results of EORTC trial 30874. EORTC GU Group
    S D Fossa
    Department of Medical Oncology and Radiotherapy, Norwegian Radium Hospital, Oslo
    Br J Cancer 71:619-24. 1995
    ..The HOP chemotherapy regimen is highly effective in patients with advanced metastatic seminoma or those relapsing after previous radiotherapy, but is associated with a high risk of toxicity, in particular myelotoxicity...
  55. ncbi request reprint A comparison of different modes for the detection of p53 protein accumulation. A study of bladder cancer
    S M Kraggerud
    Department of Cell Biology, Norwegian Radium Hospital, Montebello, Oslo, Norway
    Pathol Res Pract 193:471-8. 1997
    ..However, FCM is a more sensitive and objective method for the detection of p53 protein than IHC and this should be taken into account when routinely evaluating the p53 protein accumulation by IHC...
  56. doi request reprint CYP1A1, CYP3A5 and CYP3A7 polymorphisms and testicular cancer susceptibility
    W Kristiansen
    Faculty of Health Sciences, Oslo University College, Oslo, Norway
    Int J Androl 34:77-83. 2011
    ..This study suggests that polymorphisms in the CYP1A1 gene may contribute to variability of individual susceptibility to TC...
  57. doi request reprint Definitive radiotherapy with adjuvant long-term antiandrogen treatment for locally advanced prostate cancer: health-related quality of life and hormonal changes
    A Berg
    Faculty Division The Norwegian Radium Hospital, Faculty of Medicine, University of Oslo, Oslo, Norway
    Prostate Cancer Prostatic Dis 12:269-76. 2009
    ..05) lower on physical function and vitality. Estimated free testosterone and measured serum estradiol had increased from baseline in most patients, but did not correlate with HRQoL outcomes 5 years after the start of treatment...
  58. ncbi request reprint Regional trends in prostate cancer incidence, treatment with curative intent and mortality in Norway 1980-2007
    R Kvale
    Department of Clinical and Registry based Research, The Cancer Registry of Norway, Oslo, Norway
    Cancer Epidemiol 34:359-67. 2010
    ....
  59. ncbi request reprint Quality of life during radiotherapy for rectal cancer
    M G Guren
    Department of Clinical Cancer Research, The Norwegian Radium Hospital, Oslo, Norway
    Eur J Cancer 39:587-94. 2003
    ..HRQL scores had returned to pre-treatment levels 4-6 weeks after radiotherapy. Thus, diarrhoea, fatigue and appetite loss increased transiently during pelvic radiotherapy...
  60. ncbi request reprint TP53 and p21WAF1/CIP1 behave differently in euploid versus aneuploid bladder tumours treated with radiotherapy
    R Røtterud
    Department of Pathology, The Norwegian Radium Hospital, Montebello, Oslo
    Acta Oncol 40:644-52. 2001
    ..We conclude that DNA aneuploidy may confer increased radiosensitivity in bladder cancer patients and that TP53 accumulation may confer increased radiosensitivity, but its effect is detectable only in euploid tumours...
  61. pmc Prognostic factors in patients progressing after cisplatin-based chemotherapy for malignant non-seminomatous germ cell tumours
    S D Fossa
    Department of Medical Oncology and Radiotherapy, The Norwegian Radium Hospital, Montebello, Oslo
    Br J Cancer 80:1392-9. 1999
    ..The results of high-dose salvage chemotherapy should be interpreted on the background of these prognostic factors...
  62. doi request reprint Long-term survivorship after cancer: how far have we come?
    S D Fossa
    Department of Clinical Cancer Research, Rikshospitalet University Hospital and University of Oslo, Faculty of Medicine, Norwegian Radium Hospital, Oslo, Norway
    Ann Oncol 19:v25-9. 2008
  63. ncbi request reprint Sequential 5-fluorouracil and methotrexate. Negative experience in metastatic colorectal cancer
    E H Wanderas
    Department of Medical Oncology and Radiotherapy, Norwegian Radium Hospital, Oslo
    Acta Oncol 26:289-93. 1987
    ..The median survival was 7 months in group 1 and 10 1/2 months in group 2. Almost identical results were obtained by the two treatment schedules. The toxicity of both regimens was low...
  64. pmc Second non-germ cell malignancies after radiotherapy of testicular cancer with or without chemotherapy
    S D Fossa
    Department of Medical Oncology and Radiotherapy, Norwegian Radium Hospital, Montebello, Oslo
    Br J Cancer 61:639-43. 1990
    ..The application of the extended radiotherapy or the combination of radiotherapy and chemotherapy containing alkylating drugs should be avoided in order to reduce this excess risk...
  65. ncbi request reprint High prostate cancer mortality in Norway: influence of Cancer Registry information?
    E Hernes
    The Norwegian Radium Hospital HF, Montebello, Oslo, Norway
    APMIS 113:542-9. 2005
    ..7 to 22.9 per 100,000). In conclusion, the high rates of prostate cancer mortality in Norway could not be explained by information transfer from the CR to the COD Registry...
  66. doi request reprint [Long-term toxicity after therapy for testicular cancer with special focus on sexual disorders]
    J Oldenburg
    Department of Clinical Cancer Research, The Norwegian Radium Hospital, Montebello, 0310, Oslo, Norway
    Urologe A 48:372-6. 2009
    ..Furthermore, patients should be informed about long-term complications and their possible reduction by optimizing the risk factor profile...
  67. ncbi request reprint Prognostic significance of histologic grading in patients with prostate carcinoma who are assessed by the Gleason and World Health Organization grading systems in needle biopsies obtained prior to radiotherapy
    W Lilleby
    Department of Clinical Radiotherapy, The Norwegian Radium Hospital, The University of Oslo, Oslo, Norway
    Cancer 92:311-9. 2001
    ..The current study was conducted to evaluate and compare the impact of two major histologic grading systems on failure-free survival in patients with prostate carcinoma who are treated with definitive radiation...
  68. pmc Expression of the epidermal growth factor receptor family in prostate carcinoma before and during androgen-independence
    E Hernes
    Department of Clinical Cancer Research, The Norwegian Radium Hospital, Montebello, N 0310 Oslo, Norway
    Br J Cancer 90:449-54. 2004
    ..029). Our results support ongoing therapeutic attempts of EGFR inhibition in subgroups of patients with prostate cancer. Further research is needed to understand the function of EGFRs in this malignancy...
  69. ncbi request reprint Protein networking in bladder cancer: immunoreactivity for FGFR3, EGFR, ERBB2, KAI1, PTEN, and RAS in normal and malignant urothelium
    R Røtterud
    The Urological Research Institute, Oslo Urological University Clinic, Aker University Hospital, Oslo, Norway
    Histol Histopathol 22:349-63. 2007
    ..EGFR and KAI1 may discriminate between non-metastasised and metastasised cancers. A complex network of associations between the factors is suggested...
  70. ncbi request reprint Androgen replacement and quality of life in patients treated for bilateral testicular cancer
    S D Fossa
    Department of Medical Oncology and Radiotherapy, Norwegian Radium Hospital, Montebello, Oslo, Norway
    Eur J Cancer 35:1220-5. 1999
    ..Schedules for ARP have to be improved. In spite of intermittent hypogonadism most patients are psychosocially and sexually well adjusted to their health situation...
  71. doi request reprint A population-based study of spinal metastatic disease in South-East Norway
    O Zaikova
    Department of Oncological Surgery, Norwegian Radium Hospital, Oslo, Norway
    Clin Oncol (R Coll Radiol) 21:753-9. 2009
    ....
  72. ncbi request reprint Health technology assessment and implications for clinical practice: the case of prostate cancer screening
    I N Norderhaug
    The Norwegian Centre for Health Technology Assessment, SINTEF Unimed, Oslo, Norway
    Scand J Clin Lab Invest 63:331-8. 2003
    ..In conclusion, evidence obtained through an international collaboration such as the INAHTA collaboration may be used to develop and implement national guidelines or recommendations...
  73. ncbi request reprint Cancer patients' awareness about their diagnosis: a population-based study
    C Nord
    Department of Clinical Cancer Research, University Hospital, The Norwegian Radiumhospital, Montebello, N 0310 Oslo, Norway
    J Public Health Med 25:313-7. 2003
    ..The aim of the study was to evaluate Norwegian cancer patients' awareness of their prior cancer diagnosis in a general population-based study...
  74. pmc Dose distribution in the thyroid gland following radiation therapy of breast cancer--a retrospective study
    S Johansen
    Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, N 0310 Oslo, Norway
    Radiat Oncol 6:68. 2011
    ..To relate the development of post-treatment hypothyroidism with the dose distribution within the thyroid gland in breast cancer (BC) patients treated with loco-regional radiotherapy (RT)...
  75. ncbi request reprint The level of physical activity in long-term survivors of testicular cancer
    L Thorsen
    Department and Psychosocial Oncology and Rehabilitation, The Norwegian Radium Hospital, University of Oslo, Oslo 0310, Norway
    Eur J Cancer 39:1216-21. 2003
    ..32 (95% Confidence Interval (CI) 1.10-1.58)). The results indicate that the experience of testicular cancer increases rather than reduces the LPA in TCSs, independent of treatment given...
  76. pmc Familial testicular cancer in Norway and southern Sweden
    K Heimdal
    Department of Genetics, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway
    Br J Cancer 73:964-9. 1996
    ..2% in familial TC and 13.3% in sporadic cases). This may indicate that different factors are of importance for the development of familial TC and UDT...
  77. doi request reprint Combined positron emission tomography/computed tomography in sunitinib therapy assessment of patients with metastatic renal cell carcinoma
    M E Revheim
    Division of Imaging and Intervention, Rikshospitalet, Oslo University Hospital, Oslo, Norway
    Clin Oncol (R Coll Radiol) 23:339-43. 2011
    ....
  78. pmc Late recurrences of germ cell malignancies: a population-based experience over three decades
    J Oldenburg
    Faculty of Medicine, University of Oslo, Oslo, Norway
    Br J Cancer 94:820-7. 2006
    ..The 10-year incidence rate of late relapses of 1.3% might reflect the true incidence rate in a population-based cohort of MGCT patients, with cure in at least half of them...
  79. ncbi request reprint Twenty years experience with semen cryopreservation in testicular cancer patients: who needs it?
    H Magelssen
    The Norwegian Radium Hospital, Dep of Clinical Research, Montebello, 0310 Oslo, Norway
    Eur Urol 48:779-85. 2005
    ..To evaluate the role of semen cryopreservation (SCP) in the fertility saving management of testicular cancer (TC) patients, treated at the Norwegian Radium Hospital between 1983 and 2002...
  80. pmc Post-treatment parenthood in Hodgkin's lymphoma survivors
    C E Kiserud
    Unit for long term outcome, Department of Clinical Cancer Research, Rikshospitalet Radiumhospitalet Medical Center, Oslo, Norway
    Br J Cancer 96:1442-9. 2007
    ..In univariate analyses, age at diagnosis was a significant factor related to post-treatment parenthood in females...
  81. pmc Excessive annual BMI increase after chemotherapy among young survivors of testicular cancer
    C Nord
    Department of Medical Oncology and Radiotherapy, University Hospital, The Norwegian Radium Hospital NRH, Oslo, Norway
    Br J Cancer 88:36-41. 2003
    ..Oncologists and young TCSs should be aware of the risk of excessive BMI increase, in particular, after the use of chemotherapy...
  82. pmc Identification of nucleolar protein No55 as a tumour-associated autoantigen in patients with prostate cancer
    A Fossa
    Department of Immunology, The Norwegian Radium Hospital, Montebello, Oslo, 0310, Norway
    Br J Cancer 83:743-9. 2000
    ....
  83. ncbi request reprint Frequent promoter hypermethylation of the O6-Methylguanine-DNA Methyltransferase (MGMT) gene in testicular cancer
    B Smith-Sørensen
    Department of Tumour Biology, Institute for Cancer Research, The Norwegian Radium Hospital, 0310 Oslo, Norway
    Oncogene 21:8878-84. 2002
    ..In summary, our data suggest that inactivation of MGMT contributes to development of nonseminomatous testicular cancer...