Johan Ferno

Summary

Affiliation: University of Bergen
Country: Norway

Publications

  1. ncbi request reprint Lipogenic effects of psychotropic drugs: focus on the SREBP system
    Johan Ferno
    Department of Clinical Medicine, Dr Einar Martens Research Group for Biological Psychiatry and Bergen Mental Health Research Center, University of Bergen, Bergen, Norway
    Front Biosci (Landmark Ed) 16:49-60. 2011
  2. pmc Acute effects of orexigenic antipsychotic drugs on lipid and carbohydrate metabolism in rat
    Goran Jassim
    Dr Einar Martens Research Group for Biological Psychiatry, Department of Clinical Medicine, University of Bergen, Bergen, Norway
    Psychopharmacology (Berl) 219:783-94. 2012
  3. pmc Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells
    Audun O Vik-Mo
    Department of Clinical Medicine, University of Bergen, Dr Einar Martens Research Group for Biological Psychiatry and Bergen Mental Health Research Center, Norway
    BMC Pharmacol 9:10. 2009
  4. doi request reprint Acute clozapine exposure in vivo induces lipid accumulation and marked sequential changes in the expression of SREBP, PPAR, and LXR target genes in rat liver
    Johan Fernø
    Department of Clinical Medicine, Dr Einar Martens Research Group for Biological Psychiatry and Bergen Mental Health, Research Center, University of Bergen, Bergen, Norway
    Psychopharmacology (Berl) 203:73-84. 2009
  5. pmc Olanzapine-induced hyperphagia and weight gain associate with orexigenic hypothalamic neuropeptide signaling without concomitant AMPK phosphorylation
    Johan Fernø
    Dr Einar Martens Research Group for Biological Psychiatry, Department of Clinical Medicine, University of Bergen, Bergen, Norway
    PLoS ONE 6:e20571. 2011

Collaborators

Detail Information

Publications5

  1. ncbi request reprint Lipogenic effects of psychotropic drugs: focus on the SREBP system
    Johan Ferno
    Department of Clinical Medicine, Dr Einar Martens Research Group for Biological Psychiatry and Bergen Mental Health Research Center, University of Bergen, Bergen, Norway
    Front Biosci (Landmark Ed) 16:49-60. 2011
    ..These results provide new insight into the molecular mechanisms of psychotropic drug action and could be relevant both for their therapeutic action and metabolic adverse effects...
  2. pmc Acute effects of orexigenic antipsychotic drugs on lipid and carbohydrate metabolism in rat
    Goran Jassim
    Dr Einar Martens Research Group for Biological Psychiatry, Department of Clinical Medicine, University of Bergen, Bergen, Norway
    Psychopharmacology (Berl) 219:783-94. 2012
    ..This study aims to investigate whether orexigenic antipsychotic drugs may induce dyslipidemia and glucose disturbances in female rats through direct perturbation of metabolically active peripheral tissues, independent of prior weight gain...
  3. pmc Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells
    Audun O Vik-Mo
    Department of Clinical Medicine, University of Bergen, Dr Einar Martens Research Group for Biological Psychiatry and Bergen Mental Health Research Center, Norway
    BMC Pharmacol 9:10. 2009
    ..The aim of the present proof-of-principle study was to investigate whether such drugs also affect lipid transport and export pathways in cultured human CNS and liver cells...
  4. doi request reprint Acute clozapine exposure in vivo induces lipid accumulation and marked sequential changes in the expression of SREBP, PPAR, and LXR target genes in rat liver
    Johan Fernø
    Department of Clinical Medicine, Dr Einar Martens Research Group for Biological Psychiatry and Bergen Mental Health, Research Center, University of Bergen, Bergen, Norway
    Psychopharmacology (Berl) 203:73-84. 2009
    ..We recently showed that APDs activate lipid biosynthesis in cultured liver cells through stimulation of the sterol regulatory element-binding protein (SREBP) transcription factors...
  5. pmc Olanzapine-induced hyperphagia and weight gain associate with orexigenic hypothalamic neuropeptide signaling without concomitant AMPK phosphorylation
    Johan Fernø
    Dr Einar Martens Research Group for Biological Psychiatry, Department of Clinical Medicine, University of Bergen, Bergen, Norway
    PLoS ONE 6:e20571. 2011
    ..Our data shed new light on the hypothalamic mechanism underlying antipsychotic-induced hyperphagia and weight gain, and provide the basis for alternative targets to control energy balance...