Bjørn O Eriksen

..The aim of this study was to study predictors of rate of change in GFR in a population-based cohort...

..A high mortality pre-empted the development of renal failure in many patients. The prognosis of CKD depended strongly on gender...

..Hence, the better prediction of cardiovascular disease by cystatin C than creatinine measurements, found by others, may be due to factors other than GFR...

..Hence, we suggest that the chronicity criterion is an important determinant of the characteristics of the population of patients with CKD stages 3 and 4. This may have practical consequences in both research and clinical work...

..We investigated whether regression models using cystatin C level alone or in combination with creatinine level in principle would improve GFR estimation in the general population compared with models using creatinine level alone...

..We propose that regression-based normalization of GFR to a standardized TBW of 40 L should replace the current practice of normalizing GFR to 1.73 m(2) of body-surface area...

..Thus, estimates of cardiovascular risk associated with small changes in eGFR must be interpreted with caution...

..The aim of the present prospective, population-based study of non-diabetic individuals was to examine the association between low-grade urinary albumin-excretion, MetS, and cardiovascular morbidity and all-cause mortality...

..73 m2) and possibly a more sensitive marker for cardiovascular risk and all-cause mortality. We examined the association of cystatin C with cardiovascular morbidity and all-cause mortality in a prospective population-based study...

..Whether there is an association between the earliest stages of elevated blood pressure and variations in kidney function within the normal range in the general population has not been investigated using accurate methodology...

..A decline in renal function predicted by urinary albumin excretion was suggested. Microalbuminuria may not be a metabolic trait, but a marker mainly of renal endothelial dysfunction...

..We assessed whether impaired fasting glucose (IFG; 5.6-6.9 mmol/L), elevated HbA1c, or hyperinsulinemia are associated with hyperfiltration in the general middle-aged population...

..This study investigated whether lack of physical exercise is associated with hyperfiltration and whether exercise modifies the positive association between fasting glucose and measured GFR...

..Endpoint-data are needed to explore the clinical significance of low-grade UAE increase...

..91, 95% CI 0.59-3.22; 2.61, 95% CI 1.28-3.95 and 3.20, 95% CI 1.80-4.60). These findings suggest that even early impairment of renal function may be associated with insulin resistance and dyslipidemia, regardless of renal albumin leakage...

..The aim of this study was to cross-validate this algorithm in a patient population from Europe, and to assess its usefulness as a clinical tool...

..In this prospective population-based study, we examined whether the proinsulin:insulin ratio (PIR) or insulin:glucose ratio (IGR, an insulin resistance surrogate) predicted carotid plaque size in nondiabetic participants...