Jørgen G Bramness

..Our paper reviews the literature in this field and proposes a stress-vulnerability model for understanding the relationship between amphetamine use and psychosis...

..To investigate whether exposure to methadone affects the risk of motor vehicle accident with personal injury...

..This study shows that some patients reduced their use of benzodiazepines substantially after starting pregabalin...

..Our study aimed to explore how common the use of lithium, valproate and lamotrigine in psychiatric conditions in children and adolescents in Norway and to describe concomitant use of other psychotropic drugs...

..There have also been reports of an increasing use of the chemical precursor gamma-butyrolactone (GBL).There is currently a need for knowledge on symptoms, addictiveness and overdoses, as well as targeted preventive measures...

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..The purpose of this study was to see how different clinical tests and observations were related to blood THC concentrations and to determine whether the combined influence of THC and ethanol was different from either drug alone...

..Drugs prescribed for the treatment of insomnia can be either benzodiazepine hypnotics or the newer z-hypnotics, zopiclone and zolpidem. This paper explores possible explanations for the choice made...

..Carisoprodol, a drug used for acute lower back pain, may cause psychomotor impairment. We wanted to investigate if patients using carisoprodol had increased risk of being involved in a traffic accident...

..We wanted to investigate whether filling a prescription for zopiclone or zolpidem was associated with increased risk of road traffic accidents at a national population level. Nitrazepam and flunitrazepam were used as comparator drugs...

..The objective of the present study was to examine whether the use of lithium or valproate increased the risk of being involved in traffic accidents...

..This, together with previous publications, indicates that the population reflected in our data uses regularly prescribed carisoprodol and, to a lesser degree, drug from an illegal street market...

..We compared these groups of drivers to a group suspected of alcohol-related impairment...

..Impairing effects on psychomotor coordination and feelings of sedation were studied by comparing IMs with EMs following their ingestion of a single dose of 700 mg carisoprodol...

..To evaluate the effect of the consumption of benzodiazepines at age 40-42 years on prescription of opioids later in life...

..Carisoprodol was developed to create a drug with less potential for abuse than meprobamate. However, case reports have established carisoprodol as a drug of abuse. This paper explores the extent of potential abuse of this drug in Norway...

..The objective of the present study was to examine whether the use of antidepressants by drivers increased the risk of being involved in traffic accidents...

..To explore psychotropic drug use in the general population and in particular among non-institutionalized persons with mental distress symptoms...

..Indistinct, but important side effects might be overlooked or misunderstood. Evidence-based practice should replace prescriptions based on unclear indications...

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..The objective of this study was to investigate the role of CYP2C19 genetics in mortalities due to carisoprodol intoxication...

..Previous research has used interview or urine analysis to assess benzodiazepine use. In this study a prescription database was applied...

..There were, however, only a small number of cases where the cause of death can be attributed to use of carisoprodol alone...

..The impact of single-dose intake in non-daily users of benzodiazepines on the clinical picture of inebriation was also studied...

..The national prescription databases in Denmark, Norway and Sweden may help provide more reliable information on the epidemiology of lithium use...

..Possible impairment could further be a product of the parent drug and/or the metabolite meprobamate. The present study aimed to investigate if carisoprodol had an impairing effect by it self...

..Whether this is true in a population of benzodiazepine users is uncertain. We studied the relationship in a population of suspected drugged drivers...

..Despite the performance enhancing qualities of amphetamines demonstrated in some low dose laboratory experiments; this study revealed a positive relationship between blood amphetamines concentration and traffic related impairment...

..The main purpose of the present study was to investigate whether a physician's judgment on impairment in a real-life setting among suspected drugged drivers, was related to blood THC concentration...

..3, 95% CI: 1.5, 3.3). This study shows a dose-response effect of self-reported mental health problems on completed suicide and replicates the gender paradox observed in the general population with prospective data...

..In this registry-based study, we examined more than 100,000 Norwegian pregnancies and described the drug prescription pattern of both fathers and mothers around conception and during pregnancy (mothers)...

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..Since few laboratories routinely screen for carisoprodol it is important to keep this drug in mind when encountering intoxications displaying serotonergic symptoms...

..Patients with psychotic conditions have a high prevalence of abuse of drugs, including anticholinergic antiparkinson drugs...

..We found no clinically or statistically significant relationship between blood methamphetamine levels and severity of psychotic symptoms...

..Suicide is a major public health problem and depression is among the most important risk factors for suicide. Treatment of depression might prevent suicide. To study this hypothesis further we conducted an ecological study...

..1 amphetamine, 2.9 methamphetamine, 5.4 codeine, 1.9 morphine, and 4.7 tetrahydrocannabinol. The correlation coefficients between drug concentrations in oral fluid and blood ranged from 0.15 to 0.96 for the six most prevalent drugs...

..Heterozygous individuals with the CYP2C19*1/*2 genotype have a reduced capacity for metabolizing carisoprodol, and should probably be regarded as intermediate metabolizers of this drug...

..The ingestion of all solutions could probably have caused impairment. All the nine drugs were, however, apparent to the consumer from the altered appearance and/or taste of the beverages...