Jens Bollerslev

Summary

Affiliation: University of Oslo
Country: Norway

Publications

  1. ncbi request reprint Low-dose GH improves exercise capacity in adults with GH deficiency: effects of a 22-month placebo-controlled, crossover trial
    Jens Bollerslev
    Section of Endocrinology, The National Hospital, Oslo, Norway
    Eur J Endocrinol 153:379-87. 2005
  2. ncbi request reprint Medical observation, compared with parathyroidectomy, for asymptomatic primary hyperparathyroidism: a prospective, randomized trial
    Jens Bollerslev
    Section of Endocrinology, Department of Medicine, Rikshospitalet Radiumhospitalet Medical Center, National University Hospital, N 0027 Oslo, Norway
    J Clin Endocrinol Metab 92:1687-92. 2007
  3. doi request reprint Clinical, immunological, and genetic features of autoimmune primary adrenal insufficiency: observations from a Norwegian registry
    Martina M Erichsen
    Department of Medicine, Haukeland University Hospital, N 5021 Bergen, Norway
    J Clin Endocrinol Metab 94:4882-90. 2009
  4. doi request reprint European Society of Endocrinology Clinical Guideline: Treatment of chronic hypoparathyroidism in adults
    Jens Bollerslev
    Section of Specialized EndocrinologyClinic of Medicine, Oslo University Hospital, Oslo, NorwayFaculty of MedicineUniversity of Oslo, Oslo, NorwayDepartment of Endocrinology and Internal MedicineAarhus University Hospital, Aarhus, DenmarkDepartment of Clinical and Experimental MedicineUniversity of Pisa, Pisa, ItalyEndocrine Research UnitDepartment of Veterans Affairs, San Francisco VA Medical Center, University of California, San Francisco, California, USAEndocrine Surgery UnitHospital Universitari del Mar, Barcelona, SpainRenal DivisionGhent University Hospital, Ghent, BelgiumDivision of EndocrinologyDepartment of MedicineDepartment of Clinical EpidemiologyLeiden University Medical Center, Leiden, The NetherlandsDepartment of Clinical EpidemiologyAarhus University Hospital, Aarhus, Denmark Section of Specialized EndocrinologyClinic of Medicine, Oslo University Hospital, Oslo, NorwayFaculty of MedicineUniversity of Oslo, Oslo, NorwayDepartment of Endocrinology and Internal MedicineAarhus University Hospital, Aarhus, DenmarkDepartment of Clinical and Experimental MedicineUniversity of Pisa, Pisa, ItalyEndocrine Research UnitDepartment of Veterans Affairs, San Francisco VA Medical Center, University of California, San Francisco, California, USAEndocrine Surgery UnitHospital Universitari del Mar, Barcelona, SpainRenal DivisionGhent University Hospital, Ghent, BelgiumDivision of EndocrinologyDepartment of MedicineDepartment of Clinical EpidemiologyLeiden University Medical Center, Leiden, Department of Social Dentistry and Dental Health Education
    Eur J Endocrinol 173:G1-20. 2015
  5. doi request reprint Autosomal dominant osteopetrosis revisited: lessons from recent studies
    Jens Bollerslev
    Section of Specialized Endocrinology, Medical Clinic B, Rikshospitalet, Oslo University Hospital, N 0027 Oslo, Norway
    Eur J Endocrinol 169:R39-57. 2013
  6. pmc Parathyroid hormone, but not vitamin D, is associated with the metabolic syndrome in morbidly obese women and men: a cross-sectional study
    Jøran Hjelmesaeth
    Morbid Obesity Center, Vestfold Hospital Trust, Health Region South, Tønsberg, Norway
    Cardiovasc Diabetol 8:7. 2009
  7. ncbi request reprint New directions in pharmacological treatment of acromegaly
    Jens Bollerslev
    Rikshospitalet University Hospital, Section of Endocrinology, 0027 Oslo, Norway
    Expert Opin Investig Drugs 18:13-22. 2009
  8. doi request reprint Current evidence for recommendation of surgery, medical treatment and vitamin D repletion in mild primary hyperparathyroidism
    Jens Bollerslev
    Section of Specialized Endocrinology, Oslo University Hospital, Rikshospitalet Faculty of Medicine, University of Oslo, N 0027 Oslo, Norway
    Eur J Endocrinol 165:851-64. 2011
  9. pmc Thioredoxin interacting protein is a potential regulator of glucose and energy homeostasis in endogenous Cushing's syndrome
    Tove Lekva
    Section of Specialized Endocrinology, Department of Endocrinology, Oslo University Hospital, Oslo, Norway
    PLoS ONE 8:e64247. 2013
  10. doi request reprint Umbilical cord levels of sclerostin, placental weight, and birth weight are predictors of total bone mineral content in neonates
    Kristin Godang
    Section of Specialized Endocrinology, Department of Endocrinology, Oslo University Hospital Rikshospitalet, PO Box 4950 Nydalen, Oslo 0424, Norway
    Eur J Endocrinol 168:371-8. 2013

Detail Information

Publications76

  1. ncbi request reprint Low-dose GH improves exercise capacity in adults with GH deficiency: effects of a 22-month placebo-controlled, crossover trial
    Jens Bollerslev
    Section of Endocrinology, The National Hospital, Oslo, Norway
    Eur J Endocrinol 153:379-87. 2005
    ..No changes in QOL were seen, possibly because of a good QOL at baseline...
  2. ncbi request reprint Medical observation, compared with parathyroidectomy, for asymptomatic primary hyperparathyroidism: a prospective, randomized trial
    Jens Bollerslev
    Section of Endocrinology, Department of Medicine, Rikshospitalet Radiumhospitalet Medical Center, National University Hospital, N 0027 Oslo, Norway
    J Clin Endocrinol Metab 92:1687-92. 2007
    ..The clinical presentation of primary hyperparathyroidism (pHPT) has changed during the last half century, and the diagnosis is now more often made by chance in patients with no specific symptoms...
  3. doi request reprint Clinical, immunological, and genetic features of autoimmune primary adrenal insufficiency: observations from a Norwegian registry
    Martina M Erichsen
    Department of Medicine, Haukeland University Hospital, N 5021 Bergen, Norway
    J Clin Endocrinol Metab 94:4882-90. 2009
    ..We aimed to determine the clinical, immunological, and genetic features of a national registry-based cohort...
  4. doi request reprint European Society of Endocrinology Clinical Guideline: Treatment of chronic hypoparathyroidism in adults
    Jens Bollerslev
    Section of Specialized EndocrinologyClinic of Medicine, Oslo University Hospital, Oslo, NorwayFaculty of MedicineUniversity of Oslo, Oslo, NorwayDepartment of Endocrinology and Internal MedicineAarhus University Hospital, Aarhus, DenmarkDepartment of Clinical and Experimental MedicineUniversity of Pisa, Pisa, ItalyEndocrine Research UnitDepartment of Veterans Affairs, San Francisco VA Medical Center, University of California, San Francisco, California, USAEndocrine Surgery UnitHospital Universitari del Mar, Barcelona, SpainRenal DivisionGhent University Hospital, Ghent, BelgiumDivision of EndocrinologyDepartment of MedicineDepartment of Clinical EpidemiologyLeiden University Medical Center, Leiden, The NetherlandsDepartment of Clinical EpidemiologyAarhus University Hospital, Aarhus, Denmark Section of Specialized EndocrinologyClinic of Medicine, Oslo University Hospital, Oslo, NorwayFaculty of MedicineUniversity of Oslo, Oslo, NorwayDepartment of Endocrinology and Internal MedicineAarhus University Hospital, Aarhus, DenmarkDepartment of Clinical and Experimental MedicineUniversity of Pisa, Pisa, ItalyEndocrine Research UnitDepartment of Veterans Affairs, San Francisco VA Medical Center, University of California, San Francisco, California, USAEndocrine Surgery UnitHospital Universitari del Mar, Barcelona, SpainRenal DivisionGhent University Hospital, Ghent, BelgiumDivision of EndocrinologyDepartment of MedicineDepartment of Clinical EpidemiologyLeiden University Medical Center, Leiden, Department of Social Dentistry and Dental Health Education
    Eur J Endocrinol 173:G1-20. 2015
    ..This guideline is therefore mainly based on how patients are managed in clinical practice, as reported in small case series and based on the experiences of the authors. ..
  5. doi request reprint Autosomal dominant osteopetrosis revisited: lessons from recent studies
    Jens Bollerslev
    Section of Specialized Endocrinology, Medical Clinic B, Rikshospitalet, Oslo University Hospital, N 0027 Oslo, Norway
    Eur J Endocrinol 169:R39-57. 2013
    ..Thereby, these studies have highlighted several intriguing treatment possibilities, employing novel modes of action, which could provide benefits to the treatment of osteoporosis. ..
  6. pmc Parathyroid hormone, but not vitamin D, is associated with the metabolic syndrome in morbidly obese women and men: a cross-sectional study
    Jøran Hjelmesaeth
    Morbid Obesity Center, Vestfold Hospital Trust, Health Region South, Tønsberg, Norway
    Cardiovasc Diabetol 8:7. 2009
    ..We aimed to explore whether MS is associated with abnormal serum levels of PTH, 25(OH)D and magnesium in a population of morbidly obese patients...
  7. ncbi request reprint New directions in pharmacological treatment of acromegaly
    Jens Bollerslev
    Rikshospitalet University Hospital, Section of Endocrinology, 0027 Oslo, Norway
    Expert Opin Investig Drugs 18:13-22. 2009
    ..The aim of treatment for acromegaly is to control tumour growth, relieve symptoms and ensure biochemical cure. With specific, well-tolerated medication, long-time primary or preoperative treatment should be discussed...
  8. doi request reprint Current evidence for recommendation of surgery, medical treatment and vitamin D repletion in mild primary hyperparathyroidism
    Jens Bollerslev
    Section of Specialized Endocrinology, Oslo University Hospital, Rikshospitalet Faculty of Medicine, University of Oslo, N 0027 Oslo, Norway
    Eur J Endocrinol 165:851-64. 2011
    ..Combined therapy with calcimimetics and alendronate could be considered for patients with hypercalcaemia and overt bone disease...
  9. pmc Thioredoxin interacting protein is a potential regulator of glucose and energy homeostasis in endogenous Cushing's syndrome
    Tove Lekva
    Section of Specialized Endocrinology, Department of Endocrinology, Oslo University Hospital, Oslo, Norway
    PLoS ONE 8:e64247. 2013
    ..We recently demonstrated that the thioredoxin/TXNIP axis may mediate some detrimental effects of glucocorticoid excess on bone tissue in CS. Here we show that alterations in this axis also may affect glucose metabolism in these patients...
  10. doi request reprint Umbilical cord levels of sclerostin, placental weight, and birth weight are predictors of total bone mineral content in neonates
    Kristin Godang
    Section of Specialized Endocrinology, Department of Endocrinology, Oslo University Hospital Rikshospitalet, PO Box 4950 Nydalen, Oslo 0424, Norway
    Eur J Endocrinol 168:371-8. 2013
    ..We hypothesized that the fibroblast growth factor 23 (FGF23) system and Wnt signaling pathway are important for normal skeletal development in the offspring...
  11. doi request reprint Associations between body composition, circulating interleukin-1 receptor antagonist, osteocalcin, and insulin metabolism in active acromegaly
    Thor Ueland
    Section of Endocrinology, Research Institute for Internal Medicine, University of Oslo, N 0027 Oslo, Norway
    J Clin Endocrinol Metab 95:361-8. 2010
    ....
  12. doi request reprint Determinants of bone mass in end-stage renal failure patients at the time of kidney transplantation
    Szilveszter Dolgos
    Medical Center, Section of Nephrology, Rikshospitalet, University of Oslo, Oslo, Norway
    Clin Transplant 22:462-8. 2008
    ..Our study aimed to identify predictors of bone mass and cumulative fracture rate at the time of renal transplantation (RTx). This is important since the patients experience further substantial bone loss the first month post-transplant...
  13. doi request reprint Seasonal variation in maternal and umbilical cord 25(OH) vitamin D and their associations with neonatal adiposity
    Kristin Godang
    Section of Specialized Endocrinology, Department of Endocrinology, Oslo University Hospital Rikshospitalet, PO Box 4950 Nydalen, 0424 Oslo, Norway
    Eur J Endocrinol 170:609-17. 2014
    ....
  14. doi request reprint Epithelial splicing regulator protein 1 and alternative splicing in somatotroph adenomas
    Tove Lekva
    Section of Specialized Endocrinology and Research Institute for Internal Medicine, Oslo University Hospital, Rikshospitalet, University of Oslo, PO Box 4950 Nydalen, 0424 Oslo, Norway
    Endocrinology 154:3331-43. 2013
    ..Our study indicates that ESRP1 in somatotroph adenomas regulates transcripts that may be essential in the EMT progression and in the response to somatostatin analog treatment. ..
  15. doi request reprint TXNIP is highly regulated in bone biopsies from patients with endogenous Cushing's syndrome and related to bone turnover
    Tove Lekva
    Section of Specialized Endocrinology, Department of Endocrinology, Faculty of Medicine, University of Oslo and Oslo University Hospital, 0027 Oslo, Norway
    Eur J Endocrinol 166:1039-48. 2012
    ..The aim of the present study was to investigate the functional role of TXNIP in bone with focus on osteoblast (OB) differentiation and OB-mediated osteoclast activity and function in vitro...
  16. doi request reprint Disturbed energy metabolism after lung and heart transplantation
    Liv Forli
    Medical Department, Oslo University Hospital, Rikshospitalet, N 0027 Oslo, Norway
    Clin Transplant 25:E136-43. 2011
    ..After transplantation, a disturbed energy metabolism is indicated, where adiponectin and especially leptin are involved and a disadvantageous body composition is favored with increased body fat and decreased lean mass...
  17. doi request reprint Adiposity-related inflammation: effects of pregnancy
    Camilla M Friis
    Division of Obstetrics and Gynaecology, Oslo University Hospital Rikshospitalet, Oslo, Norway
    Obesity (Silver Spring) 21:E124-30. 2013
    ..In the nonpregnant population, there is extensive evidence of a systemic low-grade inflammatory status in relation to excess adipose tissue. Less is known about the relation during pregnancy...
  18. doi request reprint Effect of surgery on cardiovascular risk factors in mild primary hyperparathyroidism
    Jens Bollerslev
    Section of Endocrinology, Department of Medicine, Rikshospitalet, Oslo University Hospital, and University of Oslo, 0027 Oslo, Norway
    J Clin Endocrinol Metab 94:2255-61. 2009
    ..The extraskeletal effects of PTH, such as insulin resistance, arterial hypertension, and cardiovascular (CV) risk, may however be reversible by operation...
  19. pmc Newborn body fat: associations with maternal metabolic state and placental size
    Camilla M Friis
    Section for Obstetrics, Women and Children s Division, Rikshospitalet, Oslo University Hospital, Oslo, Norway
    PLoS ONE 8:e57467. 2013
    ..Secondly, we examined the relations between maternal metabolic parameters associated with BMI and placental weight...
  20. doi request reprint Gene expression profiling identifies ESRP1 as a potential regulator of epithelial mesenchymal transition in somatotroph adenomas from a large cohort of patients with acromegaly
    Tove Lekva
    Section of Specialized Endocrinology, Department of Endocrinology, and Research Institute for Internal Medicine, Oslo University Hospital, 0424 Oslo, Norway
    J Clin Endocrinol Metab 97:E1506-14. 2012
    ....
  21. doi request reprint Assessing body composition in healthy newborn infants: reliability of dual-energy x-ray absorptiometry
    Kristin Godang
    Department of Endocrinology, Oslo University Hospital, Rikshospitalet, Oslo, Norway
    J Clin Densitom 13:151-60. 2010
    ..CLP and CF measurements are appropriate for larger cohorts or when DXA is unavailable, and they provide fair rough estimations of fat mass...
  22. ncbi request reprint Bone metabolism and growth hormone deficiency. Experimental and clinical aspects
    Thor Ueland
    Section of Endocrinology, Rikshospitalet University Hospital, Oslo, Norway
    Front Horm Res 33:146-60. 2005
  23. doi request reprint Different levels of various glucocorticoid-regulated genes in corticotroph adenomas
    Johan Arild Evang
    Section of Specialized Endocrinology, Oslo University Hospital Rikshospitalet, P O Box 4950, Nydalen, 0424, Oslo, Norway
    Endocrine 44:220-7. 2013
    ..The pattern and variability of glucocorticoid resistance in corticotroph adenomas seem to correlate with a loss of the epithelial phenotype associated with corticotroph tumor dedifferentiation. ..
  24. pmc Attenuated RORC expression in the presence of EMT progression in somatotroph adenomas following treatment with somatostatin analogs is associated with poor clinical recovery
    Tove Lekva
    Section of Specialized Endocrinology, Department of Endocrinology, Oslo University Hospital, Oslo, Norway
    PLoS ONE 8:e66927. 2013
    ..Our study indicates that attenuated RORC may be involved in the poor clinical response to SA treatment in patients with acromegaly. ..
  25. doi request reprint Interleukin 1 receptor antagonist is associated with changes in body composition during physiological GH substitution in patients with adult-onset growth hormone deficiency
    Thor Ueland
    Research Institute for Internal Medicine, Rikshospitalet, Oslo University Hospital, Norway
    Clin Endocrinol (Oxf) 74:60-6. 2011
    ....
  26. doi request reprint Dietary vitamin K2 supplement improves bone status after lung and heart transplantation
    Liv Forli
    Medical Department, Rikshospitalet, Oslo University Hospital, Oslo, Norway
    Transplantation 89:458-64. 2010
    ..The aim of this randomized, double blind, prospective longitudinal study was to investigate the effect of a dietary supplement with vitamin K2 (180 microg menakinon-7) on bone mass, the first year after lung and heart transplantation...
  27. doi request reprint Early changes in bone mass, biochemical bone markers and fibroblast growth factor 23 after renal transplantation
    Szilveszter Dolgos
    Medical Center, Rikshospitalet Radiumhospitalet, University of Oslo, Oslo, Norway
    Scand J Clin Lab Invest 69:161-7. 2009
    ..We investigated early changes in bone mass and the association of these biochemical markers and FGF-23 with bone loss following renal transplantation (RTx)...
  28. doi request reprint Determinants of short-term changes in body composition following renal transplantation
    Szilveszter Dolgos
    Medical Department, Section of Nephrology and Laboratory for Renal Physiology, Rikshospitalet, Oslo, Norway
    Scand J Urol Nephrol 43:76-83. 2009
    ..The aim of this study was to quantify the early changes in body composition after transplantation and identify predictors of these changes...
  29. pmc Fetal growth versus birthweight: the role of placenta versus other determinants
    Marie Cecilie Paasche Roland
    Department of Obstetrics, Oslo University Hospital, Oslo, Norway
    PLoS ONE 7:e39324. 2012
    ..We aimed to study the effects of maternal characteristics on both birthweight and fetal growth in third trimester and introduce placental weight as a possible determinant of both birthweight and fetal growth in third trimester...
  30. doi request reprint Adipocytes as a source of increased circulating levels of nicotinamide phosphoribosyltransferase/visfatin in active acromegaly
    Nicoleta C Olarescu
    Section of Specialized Endocrinology, Oslo University Hospital, Rikshospitalet, Songnsvannsveien 20, N 0027 Oslo, Norway
    J Clin Endocrinol Metab 97:1355-62. 2012
    ..Nicotinamide phosphoribosyltransferase (NAMPT)/visfatin is a widely expressed protein with various effects on glucose and lipid metabolism, cell survival, and inflammation...
  31. ncbi request reprint Positive effects of a physiological dose of GH on markers of atherogenesis: a placebo-controlled study in patients with adult-onset GH deficiency
    Jens Bollerslev
    Section of Endocrinology, The National University Hospital, Oslo, Norway
    Eur J Endocrinol 154:537-43. 2006
    ....
  32. doi request reprint Expression of SSTR2a, but not of SSTRs 1, 3, or 5 in somatotroph adenomas assessed by monoclonal antibodies was reduced by octreotide and correlated with the acute and long-term effects of octreotide
    Olivera Casar-Borota
    Section of Specialized Endocrinology, Oslo University Hospital, Rikshospitalet, PO Box 4950 Nydalen, 0424 Oslo, Norway
    J Clin Endocrinol Metab 98:E1730-9. 2013
    ..The expression of SSTRs other than SSTR2a has not been studied in large, unselected cohorts using novel rabbit monoclonal antibodies...
  33. doi request reprint Intensity of pituitary adenoma on T2-weighted magnetic resonance imaging predicts the response to octreotide treatment in newly diagnosed acromegaly
    Ansgar Heck
    Section of Specialized Endocrinology, Oslo University Hospital, Rikshospitalet, Norway
    Clin Endocrinol (Oxf) 77:72-8. 2012
    ....
  34. ncbi request reprint The clinical response to somatostatin analogues in acromegaly correlates to the somatostatin receptor subtype 2a protein expression of the adenoma
    Stine L Fougner
    Research Institute for Internal Medicine, University of Oslo, Oslo, Norway
    Clin Endocrinol (Oxf) 68:458-65. 2008
    ..The aim of this study was to determine adenoma SSTR2a protein expression and gsp status in a large group of patients with acromegaly, and relate this to the clinical effect of octreotide...
  35. doi request reprint Reduced bone mass and increased bone turnover in postmenopausal women with epilepsy using antiepileptic drug monotherapy
    Merete Alice Lyngstad-Brechan
    Department of Neurology, Division for Clinical Neuroscience, Section for Adult Epileptology, Rikshospitalet University Hospital, Oslo, Norway
    Scand J Clin Lab Invest 68:759-66. 2008
    ..The aims of this study were to assess the occurrence of osteoporosis and fracture rate in Norwegian postmenopausal women with epilepsy using antiepileptic drugs (AEDs), and to investigate how AEDs may affect bone health...
  36. ncbi request reprint Restoration of the coupling process and normalization of bone mass following successful treatment of endogenous Cushing's syndrome: a prospective, long-term study
    Cybele Kristo
    Section of Endocrinology, Rikshospitalet University Hospital, Oslo, Norway
    Eur J Endocrinol 154:109-18. 2006
    ..Endogenous Cushing's syndrome (CS) is associated with bone loss and an increased risk of fractures. However, the long-term outcome of treatment on bone health has not been adequately clarified...
  37. doi request reprint The expression of E-cadherin in somatotroph pituitary adenomas is related to tumor size, invasiveness, and somatostatin analog response
    Stine Lyngvi Fougner
    Research Institute for Internal Medicine, Section of Endocrinology, Rikshospitalet Medical Centre, N 0027 Oslo, Norway
    J Clin Endocrinol Metab 95:2334-42. 2010
    ..In somatotroph adenomas, a variable and reduced expression of E-cadherin has been demonstrated. In addition, nuclear translocation of E-cadherin was found to correlate with pituitary tumor invasion...
  38. ncbi request reprint Age-related changes in cortical bone content of insulin-like growth factor binding protein (IGFBP)-3, IGFBP-5, osteoprotegerin, and calcium in postmenopausal osteoporosis: a cross-sectional study
    Thor Ueland
    Department of Endocrinology, and Research Institute for Internal Medicine National, University Hospital, N 0027 Oslo, Norway
    J Clin Endocrinol Metab 88:1014-8. 2003
    ..As for OPG, our findings probably represent compensatory responses to increased osteoclastic resorption...
  39. pmc Shape information from glucose curves: functional data analysis compared with traditional summary measures
    Kathrine Frey Frøslie
    Department of Biostatistics, University of Oslo, Oslo, Norway
    BMC Med Res Methodol 13:6. 2013
    ..Our mean aim was to extract information inherent in the shape of OGTT glucose curves, compare it with the information from simple summary measures, and explore the clinical usefulness of such information...
  40. doi request reprint Reduced levels of E-cadherin correlate with progression of corticotroph pituitary tumours
    Johan Arild Evang
    Section of Specialised Endocrinology, Department of Endocrinology, Oslo University Hospital, Rikshospitalet, Oslo, Norway
    Clin Endocrinol (Oxf) 75:811-8. 2011
    ....
  41. doi request reprint Adenoma granulation pattern correlates with clinical variables and effect of somatostatin analogue treatment in a large series of patients with acromegaly
    Stine Lyngvi Fougner
    Research Institute for Internal Medicine, University of Oslo, Norway
    Clin Endocrinol (Oxf) 76:96-102. 2012
    ..Gsp oncogenes are activating mutations in the Gsα subunit gene, found in approximately 40% of somatotroph adenomas...
  42. doi request reprint Increased risk of macrosomia among overweight women with high gestational rise in fasting glucose
    Nanna Voldner
    Department of Obstetrics and Gynecology, Rikshospitalet, University of Oslo, Oslo, Norway
    J Matern Fetal Neonatal Med 23:74-81. 2010
    ..We wanted to explore the effect of BMI and fasting plasma glucose (FPG), fasting plasma insulin (FPI) and insulin resistance (HOMA-IR) on the risk of newborn macrosomia...
  43. doi request reprint The glucocorticoid-induced leucine zipper gene (GILZ) expression decreases after successful treatment of patients with endogenous Cushing's syndrome and may play a role in glucocorticoid-induced osteoporosis
    Tove Lekva
    Section of Endocrinology, Department of Medicine, Research Institute for Internal Medicine, Oslo University Hospital, Rikshospitalet, N 0027 Oslo, Norway
    J Clin Endocrinol Metab 95:246-55. 2010
    ..Glucocorticoid-induced bone loss is a serious complication in patients with endogenous Cushing's syndrome. However, the mechanism(s) by which excess glucocorticoids influence bone metabolism is not completely understood...
  44. doi request reprint β-cell dysfunction in women with previous gestational diabetes is associated with visceral adipose tissue distribution
    Tove Lekva
    Research Institute for Internal MedicineOslo University Hospital, Rikshospitalet, University of Oslo, P b 4950 Nydalen, 0424 Oslo, NorwaySection of Specialized EndocrinologyDepartment of Endocrinology, Oslo University Hospital, Rikshospitalet, Oslo, NorwayFaculty of MedicineUniversity of Oslo, Oslo, NorwayDepartment of ObstetricsOslo University Hospital, Rikshospitalet, Oslo, Norway
    Eur J Endocrinol 173:63-70. 2015
    ..Glucose intolerance in pregnancy predicts an increased risk of future type 2 diabetes...
  45. doi request reprint Increased serum and bone matrix levels of the secreted Wnt antagonist DKK-1 in patients with growth hormone deficiency in response to growth hormone treatment
    Thor Ueland
    Research Institute for Internal Medicine T U, K O, P A, T L, Oslo University Hospital, Rikshospitalet, Oslo, Norway Faculty of Medicine T U, N C O, K O, P A, T L, J B, University of Oslo, Norway K G Jebsen Inflammatory Research Center T U, P A, University of Oslo, Oslo, Norway Section of Specialized Endocrinology, Department of Endocrinology N C O, A P J, K G, J B, Oslo University Hospital, Rikshospitalet, Oslo, Norway Section of Clinical Immunology and Infectious Diseases P A, Oslo University Hospital, Rikshospitalet, Oslo, Norway
    J Clin Endocrinol Metab 100:736-43. 2015
    ..Wnt signaling pathway has being acknowledged as an important modulator of bone mass and of energy metabolism in adipose tissue and in β-cells...
  46. doi request reprint Effects of parathyroidectomy versus observation on the development of vertebral fractures in mild primary hyperparathyroidism
    Karolina Lundstam
    Department of Radiology K L, M H, Institute of Clinical Sciences, The Sahlgrenska Academy at the University of Gothenburg, Sahlgrenska University Hospital, 413 46 Gothenburg, Sweden Section of Specialized Endocrinology A H, K G, J B, Oslo University Hospital, and Faculty of Medicine, University of Oslo, 0372 Oslo, Norway Clinic of Breast and Endocrine Surgery C M, Center HOC, Copenhagen University Hospital, Rigshospitalet, 2100 Copenhagen, Denmark St Olavs Hospital M B, 7030 Trondheim, Norway Departments of Molecular Medicine and Surgery, and Endocrinology Y P, Karolinska Institutet, Karolinska University Hospital, 171 77 Stockholm, Sweden Department of Surgery J E V, Haukeland University Hospital, 5021 Bergen, Norway Department of Surgical Sciences O H, University of Uppsala, 751 85 Uppsala, Sweden Department of Medicine T R, Section of Endocrinology, Diabetes and Metabolism, Sahlgrenska University Hospital, 413 45 Gothenburg, Sweden Department of Molecular Medicine and Surgery J N, Karolinska Institutet, 171 76 Stockholm, Germany
    J Clin Endocrinol Metab 100:1359-67. 2015
    ..Mild primary hyperparathyroidism (PHPT) is a common disease especially in middle-aged and elderly women. The diagnosis is frequently made incidentally and treatment strategies are widely discussed...
  47. pmc Shape information in repeated glucose curves during pregnancy provided significant physiological information for neonatal outcomes
    Kathrine Frey Frøslie
    Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway Norwegian Resource Centre for Women s Health, Division of Obstetrics and Gynaecology, Oslo University Hospital Rikshospitalet, Oslo, Norway
    PLoS ONE 9:e90798. 2014
    ....
  48. ncbi request reprint Alternative splicing of placental lactogen (CSH2) in somatotroph pituitary adenomas
    Tove Lekva
    Section of Specialized Endocrinology, Department of Endocrinology, Oslo University Hospital, Oslo, Norway
    Neuro Endocrinol Lett 36:136-42. 2015
    ..We evaluated if the mRNA levels of the GH/CSH gene cluster in somatotroph adenomas are associated with an epithelial phenotype and response to SA treatment...
  49. pmc Maternal factors associated with fetal growth and birthweight are independent determinants of placental weight and exhibit differential effects by fetal sex
    Marie Cecilie Paasche Roland
    Department of Obstetrics, Oslo University Hospital, Oslo, Norway
    PLoS ONE 9:e87303. 2014
    ....
  50. doi request reprint HDAC2 expression and variable number of repeats in exon 1 of the HDAC2 gene in corticotroph adenomas
    J Arild Evang
    Section of Specialized Endocrinology, Department of Endocrinology, Oslo University Hospital and University of Oslo, Oslo, Norway
    Clin Endocrinol (Oxf) 73:229-35. 2010
    ..This study aimed to examine HDAC2 expression in a Norwegian cohort of corticotroph adenomas, screen for exonic HDAC2 gene variants in the adenomas and correlate the results with clinical data...
  51. doi request reprint Osteoporosis is a prevalent finding in patients with solid organ failure awaiting transplantation - a population based study
    Szilveszter Dolgos
    Section of Nephrology, Department of Medicine, Rikshospitalet, Oslo, Norway
    Clin Transplant 24:E145-52. 2010
    ..General practitioners and specialists who care for these patients before they are referred for transplantation should consider measures to prevent osteoporosis at an earlier stage...
  52. ncbi request reprint Prognostic value of osteoprotegerin in heart failure after acute myocardial infarction
    Thor Ueland
    Research Institute for Internal Medicine, Section of Endocrinology, National University Hospital, Oslo, Norway
    J Am Coll Cardiol 44:1970-6. 2004
    ..We sought to determine the relationship between osteoprotegerin (OPG) and clinical outcomes in patients with heart failure (HF) after acute myocardial infarction (AMI)...
  53. doi request reprint Normal overall mortality rate in Addison's disease, but young patients are at risk of premature death
    Martina M Erichsen
    Section for Endocrinology, Department of Medicine, Haukeland University Hospital, N 5021 Bergen, Norway
    Eur J Endocrinol 160:233-7. 2009
    ..Primary adrenal insufficiency (Addison's disease) is a rare autoimmune disease. Until recently, life expectancy in Addison's disease patients was considered normal...
  54. doi request reprint The relation of psychological distress to salivary and serum cortisol levels in pregnant women shortly after the diagnosis of a structural fetal anomaly
    Anne Kaasen
    Department of Obstetrics, University of Oslo, Oslo Specialized Endocrinology, Oslo University Hospital Rikshospitalet, Oslo, Norway
    Acta Obstet Gynecol Scand 91:68-78. 2012
    ..DESIGN. A prospective, observational study. ..
  55. pmc Intra-operative MRI facilitates tumour resection during trans-sphenoidal surgery for pituitary adenomas
    Jon Ramm-Pettersen
    Department of Neurosurgery, Oslo University Hospital, 0027 Oslo, Norway
    Acta Neurochir (Wien) 153:1367-73. 2011
    ..In this prospective study, we investigated whether intra-operative magnetic resonance imaging (iMRI) can facilitate tumour resection...
  56. doi request reprint A cohort study of the effects of serum osteoprotegerin and osteoprotegerin gene polymorphisms on cardiovascular mortality in elderly women
    Thor Ueland
    Section of Endocrinology, Rikshospitalet University Hospital, Oslo, Norway
    Clin Endocrinol (Oxf) 71:828-33. 2009
    ..To investigate the role of serum osteoprotegerin (OPG) and OPG gene polymorphisms in relation to cardiovascular (CV) and all-cause mortality in elderly women...
  57. doi request reprint Dual-energy X-ray absorptiometry is a valid method to estimate visceral adipose tissue in adult patients with Prader-Willi syndrome during treatment with growth hormone
    Nicoleta Cristina Olarescu
    Section of Specialized Endocrinology N C O, A P J, K G, J B, Department of Endocrinology, Oslo University Hospital, Rikshospitalet, Faculty of Medicine N C O, J B, and Department of Biostatistics K F F, Institute of Basic Medical Sciences, University of Oslo, N 0424 Oslo, Norway and Department of Radiology A G J, Aarhus University Hospital, DK 8000 C Aarhus, Denmark
    J Clin Endocrinol Metab 99:E1727-31. 2014
    ..Visceral adipose tissue (VAT) is established as a risk factor for type 2 diabetes and cardiovascular disease, but the radiation exposure and cost of computed tomography (CT) measurements limits its daily clinical use...
  58. doi request reprint Glucose homeostasis in adults with Prader-Willi syndrome during treatment with growth hormone: results from a 12-month prospective study
    Anders Palmstrøm Jørgensen
    Section of Specialized Endocrinology, Department of Endocrinology, Oslo University Hospital, Rikshospitalet, Oslo, Norway Electronic address
    Growth Horm IGF Res 24:16-21. 2014
    ..To investigate glucose homeostasis in relation to body mass index (BMI) in adults with PWS before and after GH therapy...
  59. doi request reprint Surgical complications after transsphenoidal microscopic and endoscopic surgery for pituitary adenoma: a consecutive series of 506 procedures
    Helene Halvorsen
    Faculty of Medicine, University of Oslo, Oslo, Norway
    Acta Neurochir (Wien) 156:441-9. 2014
    ..This single-institution, consecutive series of transsphenoidal procedures included all patients in a defined population of 2.6 million inhabitants who underwent surgery during a specific time period...
  60. ncbi request reprint Serum levels of TGF-beta and fibronectin in autosomal dominant osteopetrosis in relation to underlying mutations and well-described murine counterparts
    Jens Bollerslev
    Department of Endocrinology, National University Hospital, N 0027 Oslo, Norway
    Crit Rev Eukaryot Gene Expr 13:163-71. 2003
    ..Biochemical differences among known syndromes related to mutations in the LRP5 gene indicate different underlying pathogenetic mechanisms...
  61. doi request reprint Hormonal alterations in adolescent chronic fatigue syndrome
    Vegard Bruun Wyller
    Division of Paediatrics, Oslo University Hospital, Oslo, Norway
    Acta Paediatr 99:770-3. 2010
    ..This study explored differences among adolescent chronic fatigue syndrome patients and healthy controls regarding antidiuretic hormone, the renin-angiotensin-aldosterone-system, sex hormones and cardiac peptides...
  62. ncbi request reprint [Endogenous Cushing's syndrome]
    Johan Arild Evang
    Endokrinologisk seksjon, Medisinsk avdeling, Rikshospitalet, 0027 Oslo
    Tidsskr Nor Laegeforen 126:599-602. 2006
    ..New diagnostic procedures make today's assessment more accurate. We describe which tests should be done when there is suspicion of the syndrome. Treatment options are mentioned...
  63. doi request reprint KIT protein expression and mutational status of KIT gene in pituitary adenomas
    Olivera Casar-Borota
    Faculty of Medicine, University of Oslo, 0027 Oslo, Norway
    Virchows Arch 460:171-81. 2012
    ..Our results may suggest a role of KIT in the pathogenesis of a subset of pituitary adenomas and point out the need for further research to find out if KIT-reactive adenomas could be sensitive to Imatinib Mesylate...
  64. doi request reprint Human fetoplacental and fetal liver blood flow after maternal glucose loading: a cross-sectional observational study
    Guttorm Haugen
    Department of Obstetrics, Oslo University Hospital Rikshospitalet, Oslo, Norway University of Oslo, Oslo, Norway
    Acta Obstet Gynecol Scand 93:778-85. 2014
    ..To study umbilical vein and fetal liver blood flow related to fetal anthropometric measures following maternal oral glucose loading...
  65. doi request reprint Low levels of raf kinase inhibitory protein in growth hormone-secreting pituitary adenomas correlate with poor response to octreotide treatment
    Stine Lyngvi Fougner
    Research Institute for Internal Medicine, Section of Endocrinology, University of Oslo, Oslo N 0027, Norway
    J Clin Endocrinol Metab 93:1211-6. 2008
    ....
  66. ncbi request reprint Early posttransplant serum osteoprotegerin levels predict long-term (8-year) patient survival and cardiovascular death in renal transplant patients
    Jøran Hjelmesaeth
    Department of Medicine, Rikshospitalet University Hospital, University of Oslo, Norway
    J Am Soc Nephrol 17:1746-54. 2006
    ..Early measured posttransplantation serum OPG is a highly significant independent predictor of death from any cause or CV death in white renal transplant recipients...
  67. doi request reprint Medical management of primary hyperparathyroidism: proceedings of the fourth International Workshop on the Management of Asymptomatic Primary Hyperparathyroidism
    Claudio Marcocci
    Department of Clinical and Experimental Medicine C M, University of Pisa, and Endocrine Unit 2, University Hospital of Pisa, 56124 Pisa, Italy Section of Specialized Endocrinology J B, Oslo University Hospital, Rikshospitalet and Faculty of Medicine, University of Oslo, N 0027 Oslo, Norway Department of Medicine, Divisions of Endocrinology and Geriatrics A A K, McMaster University, Hamilton, ON, Canada L8N4A6 and Endocrine Research Unit D M S, San Francisco Veterans Affairs Medical Center and Department of Medicine, University of California, San Francisco, California 94143
    J Clin Endocrinol Metab 99:3607-18. 2014
    ..The purpose of this report is to provide an update on calcium and vitamin D supplementation and medical management for those patients with PHPT who cannot or do not want to undergo surgery...
  68. doi request reprint Modifiable determinants of fetal macrosomia: role of lifestyle-related factors
    Nanna Voldner
    Department of Obstetrics and Gynecology, University of Oslo, Rikshospitalet Medical Centre, Oslo, Norway
    Acta Obstet Gynecol Scand 87:423-9. 2008
    ....
  69. ncbi request reprint Raised serum levels of interleukin-8 and interleukin-18 in relation to bone metabolism in endogenous Cushing's syndrome
    Cybele Kristo
    Section of Endocrinology, Medical Department, National University Hospital, N 0027 Oslo, Norway
    Eur J Endocrinol 146:389-95. 2002
    ....
  70. ncbi request reprint Physical activity and calcium consumption are important determinants of lower limb bone mass in older women
    Amanda Devine
    School of Medicine and Pharmacology, University of Western Australia, Nedlands, Western Australia, Australia
    J Bone Miner Res 19:1634-9. 2004
    ..1% higher hip BMD than those who did not, supporting the concept that lifestyle factors play an important role in the maintenance of lower extremity bone mass in older women...
  71. ncbi request reprint Patients with high bone mass phenotype exhibit enhanced osteoblast differentiation and inhibition of adipogenesis of human mesenchymal stem cells
    Weimin Qiu
    Laboratory for Molecular Endocrinology KMEB, Department of Endocrinology and Metabolism, University Hospital of Odense, Odense C, Denmark
    J Bone Miner Res 22:1720-31. 2007
    ..Our in vivo and in vitro results show that activated mutation T253I of LRP5 enhances osteogenesis and inhibits adipogenesis. Inactivating mutation T244M of LRP5 exerts opposite effects...
  72. doi request reprint Preoperative octreotide treatment in newly diagnosed acromegalic patients with macroadenomas increases cure short-term postoperative rates: a prospective, randomized trial
    Sven M Carlsen
    Department of Endocrinology, St Olavs Hospital, University Hospital of Trondheim, 7006 Trondheim, Norway
    J Clin Endocrinol Metab 93:2984-90. 2008
    ..Surgery is the primary treatment of acromegaly. However, it often fails to cure the patient. New strategies that improve surgical outcome are needed...
  73. ncbi request reprint [Hormonally inactive pituitary adenomas]
    Morten Lund-Johansen
    Nevrokirurgisk avdeling, Haukeland Universitetssykehus, Bergen
    Tidsskr Nor Laegeforen 123:2253-6. 2003
    ..This paper surveys hormonally inactive pituitary tumours on the basis of the current international literature; it also reflects the experience of the authors...
  74. pmc Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density
    Liesbeth Van Wesenbeeck
    Department of Medical Genetics, University of Antwerp, Antwerp, Belgium
    Am J Hum Genet 72:763-71. 2003
    ..Functional analysis of the effects of the various mutations will be of interest, to evaluate whether all the mutations give rise to the same pathogenic mechanism...
  75. ncbi request reprint [Hyperprolactinemia and prolactinemia--investigation and treatment]
    Johan Svartberg
    Endokrinologisk seksjon Medisinsk avdeling Universitetssykehuset i Nord Norge 9038 Tromsø
    Tidsskr Nor Laegeforen 122:494-8. 2002
    ..In cases of macroprolactinomas, symptoms caused by local mass effects can be seen. A variety of other conditions may also cause hyperprolactinaemia; the goal of the examination is to identify the cause...
  76. pmc Acidification of the osteoclastic resorption compartment provides insight into the coupling of bone formation to bone resorption
    Morten A Karsdal
    Nordic Bioscience A S, Herlev Hovedgade 207, DK 2730 Herlev, Denmark
    Am J Pathol 166:467-76. 2005
    ..Thus, we suggest that acidification is essential for normal bone remodeling and that attenuated acidification leads to uncoupling with decreased bone resorption and unaffected bone formation...