Alexandra Bjørk

Summary

Affiliation: University of Oslo
Country: Norway

Publications

  1. ncbi Electrostatic interactions across the dimer-dimer interface contribute to the pH-dependent stability of a tetrameric malate dehydrogenase
    Alexandra Bjørk
    Department of Biology, University of Oslo, Box 1031 Blindern, N 0316 Oslo, Norway
    FEBS Lett 553:423-6. 2003
  2. ncbi Stabilization of a tetrameric malate dehydrogenase by introduction of a disulfide bridge at the dimer-dimer interface
    Alexandra Bjørk
    Department of Biology, University of Oslo, PO Box 1031 Blindern, N 0316 Oslo, Norway
    J Mol Biol 334:811-21. 2003
  3. ncbi Large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface
    Alexandra Bjørk
    Department of Molecular Biosciences, University of Oslo, P O Box 1041, Blindern, N 0316 Oslo, Norway
    J Mol Biol 341:1215-26. 2004
  4. ncbi Structural basis for thermophilic protein stability: structures of thermophilic and mesophilic malate dehydrogenases
    Bjørn Dalhus
    Department of Chemistry, University of Oslo, Box 1033, Blindern, N 0316 Oslo, Norway
    J Mol Biol 318:707-21. 2002

Collaborators

  • Vincent G H Eijsink
  • S Ramaswamy
  • Bjørn Dalhus
  • Uwe H Sauer
  • Andreas Karlsson
  • Bjørnar Synstad
  • Kenth Johansson
  • Hans Eklund
  • Reidun Sirevåg
  • Pär Eklund
  • Kristine Naterstad
  • Markuu Saarinen

Detail Information

Publications4

  1. ncbi Electrostatic interactions across the dimer-dimer interface contribute to the pH-dependent stability of a tetrameric malate dehydrogenase
    Alexandra Bjørk
    Department of Biology, University of Oslo, Box 1031 Blindern, N 0316 Oslo, Norway
    FEBS Lett 553:423-6. 2003
    ..8 degrees C, and depended strongly on pH. Gel-filtration experiments indicated that the 26.8 degrees C loss in stability observed for the D56K mutant at low pH was accompanied by a shift towards a lower oligomerization state...
  2. ncbi Stabilization of a tetrameric malate dehydrogenase by introduction of a disulfide bridge at the dimer-dimer interface
    Alexandra Bjørk
    Department of Biology, University of Oslo, PO Box 1031 Blindern, N 0316 Oslo, Norway
    J Mol Biol 334:811-21. 2003
    ..The results show that tetramerization may contribute to MDH stability to an extent that depends strongly on the number of stabilizing interactions in the dimer-dimer interface...
  3. ncbi Large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface
    Alexandra Bjørk
    Department of Molecular Biosciences, University of Oslo, P O Box 1041, Blindern, N 0316 Oslo, Norway
    J Mol Biol 341:1215-26. 2004
    ....
  4. ncbi Structural basis for thermophilic protein stability: structures of thermophilic and mesophilic malate dehydrogenases
    Bjørn Dalhus
    Department of Chemistry, University of Oslo, Box 1033, Blindern, N 0316 Oslo, Norway
    J Mol Biol 318:707-21. 2002
    ..A structural alignment of tetrameric and dimeric prokaryotic MDHs reveal that structural elements that differ among dimeric and tetrameric MDHs are located in a few loop regions...