Silke Appel

Summary

Affiliation: University of Bergen
Country: Norway

Publications

  1. pmc The bacterial preparation OK432 induces IL-12p70 secretion in human dendritic cells in a TLR3 dependent manner
    Arnt Ove Hovden
    Broegelmann Research Laboratory, The Gade Institute, University of Bergen, Bergen, Norway
    PLoS ONE 7:e31217. 2012
  2. pmc Expression of ESE-3 isoforms in immunogenic and tolerogenic human monocyte-derived dendritic cells
    Florian Sprater
    Broegelmann Research Laboratory, The Gade Institute, University of Bergen, Bergen, Norway
    PLoS ONE 7:e49577. 2012
  3. doi request reprint Potential association of muscarinic receptor 3 gene variants with primary Sjogren's syndrome
    Silke Appel
    Broegelmann Research Laboratory, The Gade Institute, University of Bergen, Norway
    Ann Rheum Dis 70:1327-9. 2011
  4. pmc Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses
    Arnt Ove Hovden
    The Gade Institute, University of Bergen, Norway
    BMC Immunol 12:2. 2011
  5. doi request reprint The complexity of Sjögren's syndrome: novel aspects on pathogenesis
    Roland Jonsson
    Broegelmann Research Laboratory, The Gade Institute, University of Bergen, Bergen, Norway
    Immunol Lett 141:1-9. 2011
  6. doi request reprint Levels of dendritic cell populations and regulatory T cells vary significantly between two commonly used mouse strains
    Petra Vogelsang
    Broegelmann Research Laboratory, The Gade Institute, University of Bergen, Bergen, Norway
    Scand J Immunol 70:541-6. 2009
  7. doi request reprint The 2011 Nobel Prize in physiology or medicine
    Roman Volchenkov
    Broegelmann Research Laboratory, The Gade Institute, University of Bergen, Bergen, Norway
    Scand J Immunol 75:1-4. 2012
  8. ncbi request reprint CD11c(+) dendritic cells rather than Langerhans cells are reduced in normal skin of immunosuppressed renal transplant recipients
    Lene F Sandvik
    Broegelmann Research Laboratory, The Gade Institute, University of Bergen, NO 5021 Bergen, Norway
    Acta Derm Venereol 94:173-8. 2014
  9. ncbi request reprint Levels of plasmacytoid dendritic cells and type-2 myeloid dendritic cells are reduced in peripheral blood of patients with primary Sjogren's syndrome
    Petra Vogelsang
    Broegelmann Research Laboratory, The Gade Institute, University of Bergen, Laboratory building, 5th Floor, N 5021 Bergen, Norway
    Ann Rheum Dis 69:1235-8. 2010

Collaborators

Detail Information

Publications9

  1. pmc The bacterial preparation OK432 induces IL-12p70 secretion in human dendritic cells in a TLR3 dependent manner
    Arnt Ove Hovden
    Broegelmann Research Laboratory, The Gade Institute, University of Bergen, Bergen, Norway
    PLoS ONE 7:e31217. 2012
    ..OK432 demonstrates a critical ability to induce IL-12p70 production, which is of great relevance in DC based cancer immunotherapy...
  2. pmc Expression of ESE-3 isoforms in immunogenic and tolerogenic human monocyte-derived dendritic cells
    Florian Sprater
    Broegelmann Research Laboratory, The Gade Institute, University of Bergen, Bergen, Norway
    PLoS ONE 7:e49577. 2012
    ..In blood DC populations only splice variant ESE-3b was detectable. ESE-3j was not detectable in any of the DC populations. These findings suggest that ESE-3b is the functionally most important ESE-3 isoform in DC...
  3. doi request reprint Potential association of muscarinic receptor 3 gene variants with primary Sjogren's syndrome
    Silke Appel
    Broegelmann Research Laboratory, The Gade Institute, University of Bergen, Norway
    Ann Rheum Dis 70:1327-9. 2011
    ..Specifically, dysfunction of exocrine pathways involving the muscarinic receptor 3 (CHRM3) has been indicated...
  4. pmc Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses
    Arnt Ove Hovden
    The Gade Institute, University of Bergen, Norway
    BMC Immunol 12:2. 2011
    ..OK432 is an immunotherapeutic agent derived from killed Streptococcus pyogenes that has been used clinically to treat malignant and benign neoplasms for decades...
  5. doi request reprint The complexity of Sjögren's syndrome: novel aspects on pathogenesis
    Roland Jonsson
    Broegelmann Research Laboratory, The Gade Institute, University of Bergen, Bergen, Norway
    Immunol Lett 141:1-9. 2011
    ..In addition, such approaches allowed us to glimpse at the apparent complexity of Sjögren's syndrome...
  6. doi request reprint Levels of dendritic cell populations and regulatory T cells vary significantly between two commonly used mouse strains
    Petra Vogelsang
    Broegelmann Research Laboratory, The Gade Institute, University of Bergen, Bergen, Norway
    Scand J Immunol 70:541-6. 2009
    ..Therefore, we emphasize the importance of considering the proper model when comparing data sets from different mouse strains...
  7. doi request reprint The 2011 Nobel Prize in physiology or medicine
    Roman Volchenkov
    Broegelmann Research Laboratory, The Gade Institute, University of Bergen, Bergen, Norway
    Scand J Immunol 75:1-4. 2012
    ..Ralph M. Steinman received the award for the discovery of dendritic cells, a cell type bridging innate and adaptive immunity, and how these cells orchestrate immune responses...
  8. ncbi request reprint CD11c(+) dendritic cells rather than Langerhans cells are reduced in normal skin of immunosuppressed renal transplant recipients
    Lene F Sandvik
    Broegelmann Research Laboratory, The Gade Institute, University of Bergen, NO 5021 Bergen, Norway
    Acta Derm Venereol 94:173-8. 2014
    ..This finding underlines the role of DC subsets in immunosurveillance, and may have implications for our understanding of the effect of immunosuppression on DC subsets. ..
  9. ncbi request reprint Levels of plasmacytoid dendritic cells and type-2 myeloid dendritic cells are reduced in peripheral blood of patients with primary Sjogren's syndrome
    Petra Vogelsang
    Broegelmann Research Laboratory, The Gade Institute, University of Bergen, Laboratory building, 5th Floor, N 5021 Bergen, Norway
    Ann Rheum Dis 69:1235-8. 2010
    ..This study quantified interferon-producing plasmacytoid DC (pDC) and two myeloid DC subsets (mDC1 and mDC2) in peripheral blood (PB) from primary SS (pSS) patients and healthy controls...