Ole A Andreassen

Summary

Affiliation: University of Oslo
Country: Norway

Publications

  1. ncbi request reprint [Pharmacogenetics and tailored drug treatment in schizophrenia]
    Ole A Andreassen
    Institutt for psykiatri, Universitetet i Oslo
    Tidsskr Nor Laegeforen 126:2400-2. 2006
  2. pmc Measuring cognitive insight in schizophrenia and bipolar disorder: a comparative study
    John A Engh
    Division of Psychiatry, Ulleval University Hospital, Oslo, Norway
    BMC Psychiatry 7:71. 2007
  3. doi request reprint Can learning potential in schizophrenia be assessed with the standard CVLT-II? An exploratory study
    Anja Vaskinn
    Institute of Psychiatry, University of Oslo, Norway
    Scand J Psychol 49:179-86. 2008
  4. doi request reprint The validity of d prime as a working memory index: results from the "Bergen n-back task"
    Beathe C Haatveit
    Department of Psychiatry, Oslo University Hospital, Ullevaal, Norway
    J Clin Exp Neuropsychol 32:871-80. 2010
  5. doi request reprint Decreased self-reported arousal in schizophrenia during aversive picture viewing compared to bipolar disorder and healthy controls
    Sofie R Aminoff
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Psychiatry Res 185:309-14. 2011
  6. pmc Boosting the power of schizophrenia genetics by leveraging new statistical tools
    Ole A Andreassen
    To whom correspondence should be addressed NORMENT, KG Jebsen Centre for Psychosis Research, Oslo University Hospital, Building 49, Ulleval, Kirkeveien 166, PO Box 4956, Nydalen, 0424 Oslo, Norway tel 47 23 02 73 50 22 11 78 43 dir, fax 47 23 02 73 33, E mail
    Schizophr Bull 40:13-7. 2014
  7. pmc Neurocognitive profiles in treatment-resistant bipolar I and bipolar II disorder depression
    Ute Kessler
    Moodnet Research Group, Psychiatric Division, Haukeland University Hospital, Bergen, Norway
    BMC Psychiatry 13:105. 2013
  8. pmc Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors
    Ole A Andreassen
    K G Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo 0407, Norway
    Am J Hum Genet 92:197-209. 2013
  9. pmc Self-esteem is associated with premorbid adjustment and positive psychotic symptoms in early psychosis
    Kristin Lie Romm
    Division of Mental Health and Addiction, Oslo University Hospital, 0407 Oslo, Norway
    BMC Psychiatry 11:136. 2011
  10. pmc Previous hospital admissions and disease severity predict the use of antipsychotic combination treatment in patients with schizophrenia
    Albert Bolstad
    Department of Psychiatry Research, Diakonhjemmet Hospital, P O Box 85 Vinderen, Oslo 0319, Norway
    BMC Psychiatry 11:126. 2011

Detail Information

Publications107 found, 100 shown here

  1. ncbi request reprint [Pharmacogenetics and tailored drug treatment in schizophrenia]
    Ole A Andreassen
    Institutt for psykiatri, Universitetet i Oslo
    Tidsskr Nor Laegeforen 126:2400-2. 2006
    ..Molecular genetic techniques seem to have a potential for identifying biological predictors of drug response and side effects, and help to establish tailored drug treatment...
  2. pmc Measuring cognitive insight in schizophrenia and bipolar disorder: a comparative study
    John A Engh
    Division of Psychiatry, Ulleval University Hospital, Oslo, Norway
    BMC Psychiatry 7:71. 2007
    ..The relationship between the BCIS as a measure of cognitive insight and established methods for assessment of insight of illness was explored in both diagnostic groups...
  3. doi request reprint Can learning potential in schizophrenia be assessed with the standard CVLT-II? An exploratory study
    Anja Vaskinn
    Institute of Psychiatry, University of Oslo, Norway
    Scand J Psychol 49:179-86. 2008
    ..This standard administration approach is a promising, time-saving alternative to the modified tests of learning potential used so far...
  4. doi request reprint The validity of d prime as a working memory index: results from the "Bergen n-back task"
    Beathe C Haatveit
    Department of Psychiatry, Oslo University Hospital, Ullevaal, Norway
    J Clin Exp Neuropsychol 32:871-80. 2010
    ..d ' has the advantage of capturing executive skills needed to perform mental operations in patients with schizophrenia, without being influenced by demographic variables or IQ...
  5. doi request reprint Decreased self-reported arousal in schizophrenia during aversive picture viewing compared to bipolar disorder and healthy controls
    Sofie R Aminoff
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Psychiatry Res 185:309-14. 2011
    ..This was more pronounced in females. The presence of lifetime psychotic symptoms did not influence emotional responses...
  6. pmc Boosting the power of schizophrenia genetics by leveraging new statistical tools
    Ole A Andreassen
    To whom correspondence should be addressed NORMENT, KG Jebsen Centre for Psychosis Research, Oslo University Hospital, Building 49, Ulleval, Kirkeveien 166, PO Box 4956, Nydalen, 0424 Oslo, Norway tel 47 23 02 73 50 22 11 78 43 dir, fax 47 23 02 73 33, E mail
    Schizophr Bull 40:13-7. 2014
    ....
  7. pmc Neurocognitive profiles in treatment-resistant bipolar I and bipolar II disorder depression
    Ute Kessler
    Moodnet Research Group, Psychiatric Division, Haukeland University Hospital, Bergen, Norway
    BMC Psychiatry 13:105. 2013
    ....
  8. pmc Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors
    Ole A Andreassen
    K G Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo 0407, Norway
    Am J Hum Genet 92:197-209. 2013
    ..Together, these findings suggest the feasibility of using genetic-pleiotropy-informed methods for improving gene discovery in SCZ and identifying potential mechanistic relationships with various CVD risk factors...
  9. pmc Self-esteem is associated with premorbid adjustment and positive psychotic symptoms in early psychosis
    Kristin Lie Romm
    Division of Mental Health and Addiction, Oslo University Hospital, 0407 Oslo, Norway
    BMC Psychiatry 11:136. 2011
    ..The main aims of the study were to examine whether premorbid adjustment has an impact on the subject's self-esteem, and whether lowered self-esteem contributes to the development of delusions and hallucinations...
  10. pmc Previous hospital admissions and disease severity predict the use of antipsychotic combination treatment in patients with schizophrenia
    Albert Bolstad
    Department of Psychiatry Research, Diakonhjemmet Hospital, P O Box 85 Vinderen, Oslo 0319, Norway
    BMC Psychiatry 11:126. 2011
    ....
  11. pmc Apathy is associated with executive functioning in first episode psychosis
    Ann Faerden
    Ulleval University Hospital, 0407 Oslo, Norway
    BMC Psychiatry 9:1. 2009
    ....
  12. pmc The study protocol of the Norwegian randomized controlled trial of electroconvulsive therapy in treatment resistant depression in bipolar disorder
    Ute Kessler
    Moodnet Research Group, Haukeland University Hospital, Bergen, Norway
    BMC Psychiatry 10:16. 2010
    ..Cognitive changes and quality of life during the treatment will be assessed...
  13. pmc The estrogen hypothesis of schizophrenia implicates glucose metabolism: association study in three independent samples
    Line Olsen
    Research Institute of Biological Psychiatry, Sct, Hans Hospital, DK 4000 Roskilde, Denmark
    BMC Med Genet 9:39. 2008
    ..Thus, we tested the hypothesis that variants of the glycolytic genes are associated with schizophrenia or at least with gender-associated aspects of the illness...
  14. doi request reprint Sex-specific cortisol levels in bipolar disorder and schizophrenia during mental challenge--relationship to clinical characteristics and medication
    Nils Eiel Steen
    Psychosis Research Unit, Division of Mental Health and Addiction, Oslo University Hospital, Ulleval Hospital, P O Box 4956 Nydalen, 0424 Oslo, Norway
    Prog Neuropsychopharmacol Biol Psychiatry 35:1100-7. 2011
    ....
  15. doi request reprint Subcortical brain volumes relate to neurocognition in schizophrenia and bipolar disorder and healthy controls
    Cecilie B Hartberg
    Institute of Clinical Medicine, Psychiatry Section, University of Oslo, Norway
    Prog Neuropsychopharmacol Biol Psychiatry 35:1122-30. 2011
    ..It is unknown whether relationships between subcortical volumes and neurocognitive performance are similar or different between schizophrenia and bipolar disorder...
  16. doi request reprint Suicidality before and in the early phases of first episode psychosis
    Elizabeth A Barrett
    Department of Mental Health, Oslo University Hospital, 0514 Oslo, Norway
    Schizophr Res 119:11-7. 2010
    ..This study explored the prevalence and characteristics of suicidality in patients with a first episode of psychosis (FEP) in two time intervals: 1) prior to study entry and 2) explicitly in the period of untreated psychosis...
  17. doi request reprint Dysbindin and d-amino-acid-oxidase gene polymorphisms associated with positive and negative symptoms in schizophrenia
    Katrine V Wirgenes
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Neuropsychobiology 60:31-6. 2009
    ....
  18. doi request reprint Using the Wisconsin Card Sorting Test to assess learning potential in normal IQ schizophrenia: does it have potential?
    Anja Vaskinn
    Institute of Psychiatry, University of Oslo, and Oslo University Hospital, Aker, Norway
    Nord J Psychiatry 63:405-11. 2009
    ..Learning potential, a dynamic multi-administration approach to assessment, is claimed to predict functional outcome in schizophrenia better than traditional single-administration neuropsychological tests...
  19. pmc Neurocognitive features in subgroups of bipolar disorder
    Sofie Ragnhild Aminoff
    KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Ullevaal Hospital, Oslo, Norway
    Bipolar Disord 15:272-83. 2013
    ..To examine which subgroups of DSM-IV bipolar disorder (BD) [BD type I (BD-I) or BD type II (BD-II), and subgroups based on history of psychosis, presenting polarity, and age at onset] differentiate best regarding neurocognitive measures...
  20. doi request reprint Suicidality in first episode psychosis is associated with insight and negative beliefs about psychosis
    Elizabeth A Barrett
    Department of Mental Health and Addiction, Oslo University Hospital, 0424 Oslo, Norway
    Schizophr Res 123:257-62. 2010
    ....
  21. doi request reprint Depression and depressive symptoms in first episode psychosis
    Kristin Lie Romm
    Department of Psychiatry, Oslo University Hospital, Ulleval, Oslo, Norway
    J Nerv Ment Dis 198:67-71. 2010
    ..Thus depressive symptoms are frequent among FEPP, with indications of gender specific differences in patient characteristics that might imply different approaches to treatment...
  22. doi request reprint Cannabis use and premorbid functioning as predictors of poorer neurocognition in schizophrenia spectrum disorder
    P Andreas Ringen
    KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital, N 0424 Oslo, Norway
    Schizophr Res 143:84-9. 2013
    ..We investigated the relation between cannabis use, determined by its presence in urine, and neurocognitive functioning in schizophrenia controlling for the potential bias of premorbid functioning...
  23. pmc Association of genetic variants on 15q12 with cortical thickness and cognition in schizophrenia
    Trygve E Bakken
    The Scripps Research Institute, Scripps Translational Science Institute, 3344 N Torrey Pines Court, La Jolla, CA 92037, USA
    Arch Gen Psychiatry 68:781-90. 2011
    ..Identifying genes that contribute to variation in cortical thickness provides a means to elucidate some of the biological mechanisms underlying these diseases and general cognitive abilities...
  24. pmc Apathy, poor verbal memory and male gender predict lower psychosocial functioning one year after the first treatment of psychosis
    Ann Faerden
    Oslo University Hospital, Ulleval, 0407 Oslo, Norway Electronic address
    Psychiatry Res 210:55-61. 2013
    ..Apathy is a negative symptom associated with poor psychosocial functioning in schizophrenia but has not been sufficiently studied as predictor of poor functioning in first episode psychosis (FEP)...
  25. doi request reprint Interleukin 1 receptor antagonist and soluble tumor necrosis factor receptor 1 are associated with general severity and psychotic symptoms in schizophrenia and bipolar disorder
    Sigrun Hope
    KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    Schizophr Res 145:36-42. 2013
    ..We investigated if elevated inflammation was associated with disease severity (trait) or current symptom level (state), comparing psychotic with general characteristics...
  26. doi request reprint Sex differences in neuropsychological performance and social functioning in schizophrenia and bipolar disorder
    Anja Vaskinn
    Oslo University Hospital, Psychosis Research Unit, Oslo, Norway
    Neuropsychology 25:499-510. 2011
    ..To investigate sex differences in neurocognition and social functioning in schizophrenia and bipolar disorder and the possible role of sex as a moderator of this relationship...
  27. doi request reprint ZNF804A and cortical thickness in schizophrenia and bipolar disorder
    Orjan Bergmann
    KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    Psychiatry Res 212:154-7. 2013
    ..Results show no significant associations...
  28. doi request reprint Association analysis of ANK3 gene variants in nordic bipolar disorder and schizophrenia case-control samples
    Martin Tesli
    Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 156:969-74. 2011
    ..These results further support that ANK3 is a susceptibility gene specific to BD and that more than one risk locus is involved...
  29. doi request reprint Association study of PDE4B gene variants in Scandinavian schizophrenia and bipolar disorder multicenter case-control samples
    Anna K Kähler
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 153:86-96. 2010
    ..Further studies are needed to evaluate the implicated PDE4B region of interest, for potential involvement in SZ and BP susceptibility...
  30. doi request reprint BDNF val66met modulates the association between childhood trauma, cognitive and brain abnormalities in psychoses
    Monica Aas
    Institute of Clinical Medicine, University of Oslo, Norway Psychosis Research Unit, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway Electronic address
    Prog Neuropsychopharmacol Biol Psychiatry 46:181-8. 2013
    ....
  31. doi request reprint Psychosocial function in schizophrenia and bipolar disorder: Relationship to neurocognition and clinical symptoms
    Carmen Simonsen
    Psychosis Research Section, Oslo University Hospital, Oslo, Norway
    J Int Neuropsychol Soc 16:771-83. 2010
    ..Despite differences in neurocognition and psychosocial function, groups showed the same pattern in prediction of functioning irrespective of DSM-IV or clinical definition...
  32. pmc CACNA1C risk variant and amygdala activity in bipolar disorder, schizophrenia and healthy controls
    Martin Tesli
    Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    PLoS ONE 8:e56970. 2013
    ....
  33. doi request reprint Neurocognitive functioning and suicidality in schizophrenia spectrum disorders
    Elizabeth A Barrett
    Department of Mental Health and Addiction, Oslo University Hospital, 0424 Oslo, Norway
    Compr Psychiatry 52:156-63. 2011
    ....
  34. doi request reprint A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample
    Srdjan Djurovic
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    J Affect Disord 126:312-6. 2010
    ..In the present study we investigated genetic variants associated with bipolar disorder in a homogenous Norwegian sample, and potential genetic overlap with schizophrenia, using the Affymetrix 6.0 array...
  35. pmc Clinical characteristics in schizophrenia patients with or without suicide attempts and non-suicidal self-harm--a cross-sectional study
    Erlend Mork
    National Centre for Suicide Research and Prevention, Institute of Clinical Medicine, University of Oslo, Sognsvannsveien 21, 0372 Oslo, Norway
    BMC Psychiatry 13:255. 2013
    ....
  36. doi request reprint Cardiovascular risk factors during second generation antipsychotic treatment are associated with increased C-reactive protein
    Ingrid Dieset
    Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    Schizophr Res 140:169-74. 2012
    ..We investigated whether there is a relationship between CVD risk factors and inflammation in schizophrenia or bipolar disorder, and if second generation antipsychotics (SGA) interact...
  37. doi request reprint Factors associated with occupational and academic status in patients with first-episode psychosis with a particular focus on neurocognition
    Marte Tandberg
    Division of Mental Health and Addiction, Oslo University Hospital, 0407 Oslo, Norway
    Soc Psychiatry Psychiatr Epidemiol 47:1763-73. 2012
    ..Further, it investigated the relationship between students, employed and unemployed patients and clinical, neurocognitive, global, and social functioning...
  38. doi request reprint Neurocognitive functioning in patients recently diagnosed with bipolar disorder
    Tone Hellvin
    Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    Bipolar Disord 14:227-38. 2012
    ..In this study we compare neurocognitive function in a cohort of first-contact mania patients with a healthy control group matched for age, gender, and education...
  39. doi request reprint Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area
    Anna K Kähler
    Institute of Psychiatry, University of Oslo, Oslo University Hospital Ulleval, Norway
    Biol Psychiatry 69:90-6. 2011
    ..Extracellular matrix structures called perineuronal nets, condensed around subsets of neurons and proximal dendrites during brain maturation, regulate synaptic transmission and plasticity...
  40. doi request reprint Investigating relationships between cortical thickness and cognitive performance in patients with schizophrenia and healthy adults
    Cecilie Bhandari Hartberg
    Institute of Psychiatry, section Vinderen, University of Oslo, Oslo, Norway
    Psychiatry Res 182:123-33. 2010
    ....
  41. pmc Excessive cannabis use is associated with earlier age at onset in bipolar disorder
    Trine V Lagerberg
    Department of Research and Development, Division of Mental Health and Addiction, Oslo University Hospital, Norway
    Eur Arch Psychiatry Clin Neurosci 261:397-405. 2011
    ..This indicates that an early onset may increase the risk of cannabis use and that cannabis use may trigger bipolar disorder in vulnerable individuals...
  42. doi request reprint Severe social anxiety in early psychosis is associated with poor premorbid functioning, depression, and reduced quality of life
    Kristin Lie Romm
    Psychosis Research Unit, Division of Mental Health and Addiction, Oslo University Hospital, 0407 Oslo, Norway
    Compr Psychiatry 53:434-40. 2012
    ..Furthermore, we wanted to explore whether social anxiety is associated with reduced quality of life (QoL)...
  43. doi request reprint Social cognition and clinical insight in schizophrenia and bipolar disorder
    Anja Vaskinn
    KG Jebsen Centre for Psychosis Research, Oslo University Hospital, Oslo, Norway
    J Nerv Ment Dis 201:445-51. 2013
    ..Poorer insight was associated with higher symptom load. Social cognition seems to be of importance for clinical insight in schizophrenia, whereas symptoms are important in bipolar I disorder...
  44. doi request reprint Is cognitive impairment following early life stress in severe mental disorders based on specific or general cognitive functioning?
    Monica Aas
    Institute of Clinical Medicine, University of Oslo, Norway
    Psychiatry Res 198:495-500. 2012
    ..Moreover, these dysfunctions seem to be driven by underlying deficits in general cognitive tasks as measured by the WASI...
  45. doi request reprint Genome-wide association study identifies genetic loci associated with body mass index and high density lipoprotein-cholesterol levels during psychopharmacological treatment - a cross-sectional naturalistic study
    Lavinia Athanasiu
    Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    Psychiatry Res 197:327-36. 2012
    ..This deserves to be replicated in additional populations to provide more evidence for molecular genetic mechanisms of side effects during psychopharmacological treatment...
  46. pmc Neurocognitive dysfunction in bipolar and schizophrenia spectrum disorders depends on history of psychosis rather than diagnostic group
    Carmen Simonsen
    Department of Psychology, University of Oslo, 0317 Oslo, Norway
    Schizophr Bull 37:73-83. 2011
    ..We asked whether neurocognitive dysfunction in bipolar and schizophrenia spectrum disorders depends more on history of psychosis than diagnostic category or subtype...
  47. doi request reprint Cortical volume, surface area, and thickness in schizophrenia and bipolar disorder
    Lars M Rimol
    Division of Mental Health and Addiction, Institute of Clinical Medicine, University of Oslo, Norway
    Biol Psychiatry 71:552-60. 2012
    ....
  48. doi request reprint Effect of DISC1 SNPs on brain structure in healthy controls and patients with a history of psychosis
    Anna K Kähler
    Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 159:722-30. 2012
    ..In conclusion, DISC1 SNPs might impact brain structural variation, possibly differently in psychosis patients versus controls, but independent replication will be needed to confirm our findings...
  49. doi request reprint Genome-wide study identifies PTPRO and WDR72 and FOXQ1-SUMO1P1 interaction associated with neurocognitive function
    Marissa Leblanc
    Epi Gen, Institute of Clinical Medicine, Akershus University Hospital, University of Oslo, Oslo, Norway
    J Psychiatr Res 46:271-8. 2012
    ..We performed a genome-wide association study (GWAS) to identify genes associated with neurocognition...
  50. pmc Serotonin transporter gene polymorphism, childhood trauma, and cognition in patients with psychotic disorders
    Monica Aas
    Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    Schizophr Bull 38:15-22. 2012
    ..We hypothesize that 5-HTTLPR variations and long-term effects of childhood trauma interact and contribute to some of the variation in cognitive dysfunction seen in patients with psychotic disorders...
  51. doi request reprint Catechol O-methyltransferase variants and cognitive performance in schizophrenia and bipolar disorder versus controls
    Katrine V Wirgenes
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Schizophr Res 122:31-7. 2010
    ..However, the results have been inconsistent and there are few studies addressing other COMT single nucleotide polymorphisms (SNPs)...
  52. doi request reprint Increased systemic cortisol metabolism in patients with schizophrenia and bipolar disorder: a mechanism for increased stress vulnerability?
    Nils Eiel Steen
    Section for Psychosis Research, Clinic of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    J Clin Psychiatry 72:1515-21. 2011
    ....
  53. pmc Perceived discrimination is associated with severity of positive and depression/anxiety symptoms in immigrants with psychosis: a cross-sectional study
    Akiah O Berg
    Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway
    BMC Psychiatry 11:77. 2011
    ..We investigated if perceived discrimination was associated with the severity of these symptoms among immigrants in Norway with psychotic disorders...
  54. doi request reprint Associations between variants near a monoaminergic pathways gene (PHOX2B) and amygdala reactivity: a genome-wide functional imaging study
    Olga Therese Ousdal
    Oslo University Hospital, Oslo, Norway
    Twin Res Hum Genet 15:273-85. 2012
    ....
  55. doi request reprint High prevalence of childhood trauma in patients with schizophrenia spectrum and affective disorder
    Sara Larsson
    Department of Research and Development, Clinic of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    Compr Psychiatry 54:123-7. 2013
    ....
  56. doi request reprint Treatment delay and excessive substance use in bipolar disorder
    Trine Vik Lagerberg
    Psychosis Research Unit, Division of Mental Health and Addiction, Department of Research and Development, Oslo University Hospital, Oslo, Norway
    J Nerv Ment Dis 198:628-33. 2010
    ..Patients with antecedent excessive substance use had reduced risk of long treatment delays. The risk of developing excessive substance use after BD onset increased with longer treatment delays...
  57. doi request reprint Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE)
    Srdjan Djurovic
    Institute of Psychiatry, University of Oslo, Norway
    Psychiatry Res 168:256-8. 2009
    ..We report, for the first time, a possible involvement of MCTP2 as a potential novel susceptibility gene for schizophrenia...
  58. doi request reprint Association analysis of PALB2 and BRCA2 in bipolar disorder and schizophrenia in a scandinavian case-control sample
    Martin Tesli
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 153:1276-82. 2010
    ..Our findings support PALB2 and BRCA2 as risk genes specifically for BD, and suggest that altered DNA repair related to neurogenesis may be involved in BD pathophysiology. © 2010 Wiley-Liss, Inc...
  59. doi request reprint The neural correlates of cognitive control in bipolar I disorder: an fMRI study of medial frontal cortex activation during a Go/No-go task
    Audun Welander-Vatn
    Institute of Clinical Medicine, Section of Psychiatry, University of Oslo, 0318 Oslo, Norway
    Neurosci Lett 549:51-6. 2013
    ..Although the patients display some deviances in behavioural measures, this study reveals no significant differences between BD I subjects and healthy controls in recruitment of the medial frontal cortex during a Go/No-go task. ..
  60. doi request reprint An association between affective lability and executive functioning in bipolar disorder
    Sofie Ragnhild Aminoff
    Institute of Clinical Medicine, University of Oslo P O Box 1171 Blindern, N 0318 Oslo, Norway
    Psychiatry Res 198:58-61. 2012
    ....
  61. doi request reprint Common sequence variants in the major histocompatibility complex region associate with cerebral ventricular size in schizophrenia
    Ingrid Agartz
    Institute of Clinical Medicine, Department of Biostatistics, University of Oslo, Oslo, Norway
    Biol Psychiatry 70:696-8. 2011
    ..3-22.1 has been implicated in the development of schizophrenia...
  62. doi request reprint Validation of the Norwegian version of the Social Functioning Scale (SFS) for schizophrenia and bipolar disorder
    Tone Hellvin
    Institute of Psychiatry, University of Oslo, Oslo University Hospital Ulleval, Oslo, Norway
    Scand J Psychol 51:525-33. 2010
    ..Thus, SFS adds valuable information as a supplement to standard clinician-rated assessment tools of social functioning, suited both for research and clinical work...
  63. doi request reprint Social functioning in first contact mania: clinical and neurocognitive correlates
    Tone Hellvin
    Division of Mental Health and Addiction, Oslo University Hospital, PO Box 4956 Nydalen, 0424 Oslo, Norway
    Compr Psychiatry 54:432-8. 2013
    ..To study social functioning, and its relationship with clinical and neurocognitive variables, in patients having their first treatment contact for a manic episode...
  64. doi request reprint Self-harm in patients with schizophrenia spectrum disorders
    Erlend Mork
    National Centre for SuicideResearch and Prevention, Institute ofClinical Medicine, University of Oslo, Oslo, Norway
    Arch Suicide Res 16:111-23. 2012
    ..We conclude that while self-harm in patients with schizophrenia spectrum disorders is highly prevalent in both genders, risk factors in men and women differ in several important ways...
  65. pmc Patterns of childhood adverse events are associated with clinical characteristics of bipolar disorder
    Sara Larsson
    Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    BMC Psychiatry 13:97. 2013
    ....
  66. doi request reprint An exploratory model for G x E interaction on hippocampal volume in schizophrenia; obstetric complications and hypoxia-related genes
    Unn Kristin Haukvik
    Department of Clinical Medicine, section Vinderen, University of Oslo, Norway
    Prog Neuropsychopharmacol Biol Psychiatry 34:1259-65. 2010
    ....
  67. pmc Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort
    Lavinia Athanasiu
    Institute of Psychiatry, University of Oslo, P O 1130, Blindern, N 0318 Oslo, Norway
    J Psychiatr Res 44:748-53. 2010
    ..The association of ANK3 with schizophrenia is intriguing in light of recent associations of ANK3 with bipolar disorder, thereby supporting the hypothesis of an overlap in genetic susceptibility between these psychopathological entities...
  68. doi request reprint Altered systemic cortisol metabolism in bipolar disorder and schizophrenia spectrum disorders
    Nils Eiel Steen
    KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway Institute of Clinical Medicine, University of Oslo, Oslo, Norway Drammen District Psychiatric Center, Clinic of Mental Health and Addiction, Vestre Viken Hospital Trust, Drammen, Norway Electronic address
    J Psychiatr Res 52:57-62. 2014
    ..The design makes it impossible to determine the direction of the effect. However, the findings merit further study of cortisol metabolism as a possible component in the HPA axis dysfunction and pathophysiology of BD and SCZ...
  69. pmc Excessive substance use in bipolar disorder is associated with impaired functioning rather than clinical characteristics, a descriptive study
    Trine V Lagerberg
    Section for Psychosis Research, Oslo University Hospital, Bygg 49, Kirkevn, 166 N 0407 Oslo, Norway
    BMC Psychiatry 10:9. 2010
    ....
  70. doi request reprint Apathy in first episode psychosis patients: one year follow up
    Ann Faerden
    Oslo University Hospital, Ulleval, 0407 Oslo, Norway
    Schizophr Res 116:20-6. 2010
    ....
  71. doi request reprint SRD5A2 is associated with increased cortisol metabolism in schizophrenia spectrum disorders
    Nils Eiel Steen
    Section for Psychosis Research, Clinic of Mental Health and Addiction, Oslo University Hospital, Ulleval Hospital, P O Box 4956 Nydalen, 0424 Oslo, Norway
    Prog Neuropsychopharmacol Biol Psychiatry 34:1500-6. 2010
    ..We investigated whether five genes involved in cortisol metabolism were associated with altered activity of cortisol metabolizing enzymes in bipolar disorder (BD) and schizophrenia spectrum disorders (SCZ)...
  72. doi request reprint Evidence for a possible association of neurotrophin receptor (NTRK-3) gene polymorphisms with hippocampal function and schizophrenia
    Mona K Otnaess
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Neurobiol Dis 34:518-24. 2009
    ..The present results, although not robust, suggest that the NTRK-3 gene influences hippocampal function and may modify the risk for schizophrenia...
  73. pmc Aversive event anticipation affects connectivity between the ventral striatum and the orbitofrontal cortex in an fMRI avoidance task
    Ingeborg Bolstad
    KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    PLoS ONE 8:e68494. 2013
    ..In addition, this study replicates previous findings suggesting that the task is robust. ..
  74. ncbi request reprint Evidence for reduced dentate gyrus and fimbria volume in bipolar II disorder
    Torbjørn Elvsåshagen
    Department of Neuropsychiatry and Psychosomatic Medicine, Oslo University Hospital, Oslo, Norway
    Bipolar Disord 15:167-76. 2013
    ....
  75. doi request reprint Cortical thickness and subcortical volumes in schizophrenia and bipolar disorder
    Lars M Rimol
    Department of Psychiatry, section Vinderen, University of Oslo, Oslo, Norway
    Biol Psychiatry 68:41-50. 2010
    ..The purpose of this study was to compare cortical thickness and subcortical volumes in schizophrenia and bipolar disorder, to assess differences and similarities in cortical and subcortical brain structure...
  76. pmc Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate
    Ole A Andreassen
    KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    PLoS Genet 9:e1003455. 2013
    ..Together, these findings show the feasibility of genetic pleiotropy-informed methods to improve gene discovery in SCZ and BD and indicate overlapping genetic mechanisms between these two disorders...
  77. doi request reprint No altered dorsal anterior cingulate activation in bipolar II disorder patients during a Go/No-go task: an fMRI study
    Audun S Welander-Vatn
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Bipolar Disord 11:270-9. 2009
    ..The aim of this study was to investigate whether patients with BD II showed decreased activation in the dorsal anterior cingulate cortex (dACC) as compared to healthy controls when performing a task sensitive to impulsivity...
  78. doi request reprint Social problem-solving in high-functioning schizophrenia: specific deficits in sending skills
    Anja Vaskinn
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Psychiatry Res 165:215-23. 2009
    ....
  79. doi request reprint No association between DGKH and bipolar disorder in a Scandinavian case-control sample
    Martin Tesli
    Institute of Psychiatry, Faculty Division Akershus University Hospital, University of Oslo, Oslo, Norway
    Psychiatr Genet 19:269-72. 2009
    ..We found no significant association after multiple-testing correction between any of these SNPs and BD in our sample. Thus, it is unlikely that these genetic variations confer susceptibility to BD in this large Scandinavian sample...
  80. pmc All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs
    Andrew J Schork
    Cognitive Sciences Graduate Program, University of California San Diego, La Jolla, California, United States of America
    PLoS Genet 9:e1003449. 2013
    ..05. Our analyses demonstrate an inherent stratification among GWAS SNPs with important conceptual implications that can be leveraged by statistical methods to improve the discovery of loci...
  81. doi request reprint Hormonal markers of metabolic dysregulation in patients with severe mental disorders after olanzapine treatment under real-life conditions
    Astrid B Birkenaes
    Department of Psychiatry, Akershus University Hospital, Lørenskog, Norway
    J Clin Psychopharmacol 29:109-16. 2009
    ..The present study investigated the levels of several metabolic regulatory hormones in psychiatric outpatients treated with different antipsychotics under real-life conditions...
  82. doi request reprint Neurocognitive profiles in bipolar I and bipolar II disorder: differences in pattern and magnitude of dysfunction
    Carmen Simonsen
    Department of Psychiatry, Ulleval University Hospital, and Institute of Psychology, University of Oslo, Oslo, Norway
    Bipolar Disord 10:245-55. 2008
    ..The aim of this study was to examine whether patients with bipolar I and bipolar II disorder have different neurocognitive profiles...
  83. ncbi request reprint The level of cardiovascular risk factors in bipolar disorder equals that of schizophrenia: a comparative study
    Astrid B Birkenaes
    Division of Psychiatry, Ulleval University Hospital, Oslo, Norway
    J Clin Psychiatry 68:917-23. 2007
    ..It also compares the prevalence of risk factors in each diagnostic group with the general population...
  84. doi request reprint Emotion perception and learning potential: mediators between neurocognition and social problem-solving in schizophrenia?
    Anja Vaskinn
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    J Int Neuropsychol Soc 14:279-88. 2008
    ....
  85. doi request reprint A cross-sectional study of vitamin D deficiency among immigrants and Norwegians with psychosis compared to the general population
    Akiah Ottesen Berg
    Institute of Psychiatry, University of Oslo, Oslo University Hospital, Building 49, Kirkeveien 166, N 0407 Oslo, Norway
    J Clin Psychiatry 71:1598-604. 2010
    ..This study aimed to determine vitamin D levels among immigrants and Norwegians with psychosis compared to the general population and their association to clinical characteristics...
  86. ncbi request reprint Sociodemographic characteristics and cardiovascular risk factors in patients with severe mental disorders compared with the general population
    Astrid B Birkenaes
    Department of Psychiatry, Ulleval University Hospital and University of Oslo, Norway
    J Clin Psychiatry 67:425-33. 2006
    ....
  87. ncbi request reprint Should catatonia be part of the differential diagnosis of coma?
    Erlend Hem
    Department of Behavioural Sciences in Medicine, Faculty of Medicine, University of Oslo, Norway
    Nord J Psychiatry 59:528-30. 2005
    ..We report two further cases where coma was a part of this syndrome of disturbed motility. They were successfully treated with ECT. Consequently, we suggest that catatonia may be a differential diagnosis of coma...
  88. ncbi request reprint Medication adherence in outpatients with severe mental disorders: relation between self-reports and serum level
    Halldora Jonsdottir
    Section for Psychosis Research, Department of Psychiatry, Oslo University Hospital Ulleval, Oslo, Norway
    J Clin Psychopharmacol 30:169-75. 2010
    ..In this naturalistic sample, outpatients with severe mental disorders showed relatively good adherence to prescribed medication, and self-report questionnaires seem to be a valid method for measuring adherence...
  89. doi request reprint The use of screening instruments for detecting alcohol and other drug use disorders in first-episode psychosis
    Ragnar Nesvåg
    Department of Psychiatry, Diakonhjemmet Hospital, Oslo, Norway
    Psychiatry Res 177:228-34. 2010
    ..The results of this study suggest that AUDIT and DUDIT are powerful screening instruments for detecting alcohol and other drug use disorders in patients with first-episode psychosis...
  90. pmc Osteoprotegerin levels in patients with severe mental disorders
    Sigrun Hope
    Department of Psychiatry, Østfold Hospital, Fredrikstad, Norway
    J Psychiatry Neurosci 35:304-10. 2010
    ..In the present study, we investigated whether osteoprotegerin (OPG), a member of the tumour necrosis factor receptor family involved in calcification and inflammation, is elevated in patients with severe mental disorders...
  91. doi request reprint Dyslipidemia independent of body mass in antipsychotic-treated patients under real-life conditions
    Astrid B Birkenaes
    Section for Psychosis Research, Division of Psychiatry, Ulleval University Hospital and Institute of Psychiatry, Oslo, Norway
    J Clin Psychopharmacol 28:132-7. 2008
    ..We investigated how cardiometabolic risk factors were related to body mass during treatment with different APs under real-life conditions...
  92. pmc Delusions are associated with poor cognitive insight in schizophrenia
    John A Engh
    Section of Psychosis Research, Division of Psychiatry, Ulleval University Hospital, Oslo, Norway
    Schizophr Bull 36:830-5. 2010
    ..The present findings suggest that delusions are associated with low cognitive insight, whereas solitary hallucinations may be associated with high cognitive insight...
  93. ncbi request reprint Similar immune profile in bipolar disorder and schizophrenia: selective increase in soluble tumor necrosis factor receptor I and von Willebrand factor
    Sigrun Hope
    Department of Psychiatry, Østfold Hospital, Eidsberg, Norway
    Bipolar Disord 11:726-34. 2009
    ....
  94. doi request reprint Intron 12 in NTRK3 is associated with bipolar disorder
    Lavinia Athanasiu
    Department of Psychiatry, Oslo University Hospital Ulleval, Oslo, Norway
    Psychiatry Res 185:358-62. 2011
    ....
  95. ncbi request reprint No evidence for association between bipolar disorder risk gene variants and brain structural phenotypes
    Martin Tesli
    Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    J Affect Disord 151:291-7. 2013
    ..We investigated whether these genetic risk variants could explain some of the structural brain abnormalities in BD...
  96. doi request reprint Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene
    Anna K Kähler
    TOP Project, Institute of Psychiatry, University of Oslo, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 147:1089-100. 2008
    ....
  97. ncbi request reprint Age at onset of bipolar disorder in a Norwegian catchment area sample
    Sara Larsson
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    J Affect Disord 124:174-7. 2010
    ..In addition, we examined whether age at onset influenced on time to first treatment, and if patient characteristics related to illness severity influenced age at onset...
  98. doi request reprint Measurement of insight in patients with bipolar disorder: are self-rated scales developed for patients with schizophrenia applicable?
    Halldora Jonsdottir
    Department of Psychiatry, Building 49, University of Oslo, Ulleval University Hospital, 0407 Oslo, Norway
    J Nerv Ment Dis 196:333-5. 2008
    ..This suggests a cautious use of the scale across different diagnostic groups...
  99. pmc A common MECP2 haplotype associates with reduced cortical surface area in humans in two independent populations
    Alexander H Joyner
    Scripps Translational Science Institute, 3344 North Torrey Pines Court, La Jolla, CA 92037, USA
    Proc Natl Acad Sci U S A 106:15483-8. 2009
    ..Secondary analysis showed that this allele was also associated with reduced surface area in specific cortical regions (cuneus, fusiform gyrus, pars triangularis) in both populations...
  100. ncbi request reprint Effects of CAG repeat length, HTT protein length and protein context on cerebral metabolism measured using magnetic resonance spectroscopy in transgenic mouse models of Huntington's disease
    Bruce G Jenkins
    MGH NMR Center, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA
    J Neurochem 95:553-62. 2005
    ..Our results indicate profound metabolic defects that are strongly affected by CAG repeat length, as well as gene expression levels and protein context...
  101. doi request reprint Increased expression of lipid biosynthesis genes in peripheral blood cells of olanzapine-treated patients
    Audun O Vik-Mo
    Dr Einar Martens Research Group for Biological Psychiatry and Bergen Mental Health Research Center, Department of Clinical Medicine, University of Bergen, Norway
    Int J Neuropsychopharmacol 11:679-84. 2008
    ..Transcriptional activation of lipid biosynthesis genes in peripheral blood cells of olanzapine-treated patients suggests a direct lipogenic action of antipsychotic drugs, which may be related to metabolic adverse effects...