Ingrid Agartz

Summary

Affiliation: University of Oslo
Country: Norway

Publications

  1. ncbi request reprint MR volumetry during acute alcohol withdrawal and abstinence: a descriptive study
    Ingrid Agartz
    Karolinska Institutet, Department of Clinical Neuroscience, Clinical Alcohol and Drug Addiction Research Section and Human Brain Informatics, Psychiatry Section, Karolinska Hospital, Stockholm SE 171 76, Sweden
    Alcohol Alcohol 38:71-8. 2003
  2. ncbi request reprint Brain-derived neurotrophic factor gene (BDNF) variants and schizophrenia: an association study
    Erik G Jonsson
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, SE 171 76 Stockholm, Sweden
    Prog Neuropsychopharmacol Biol Psychiatry 30:924-33. 2006
  3. ncbi request reprint BDNF gene variants and brain morphology in schizophrenia
    Ingrid Agartz
    Department of Clinical Neuroscience, Human Brain Informatics, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 141:513-23. 2006
  4. doi request reprint Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene
    Anna K Kähler
    TOP Project, Institute of Psychiatry, University of Oslo, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 147:1089-100. 2008
  5. doi request reprint A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample
    Srdjan Djurovic
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    J Affect Disord 126:312-6. 2010
  6. pmc Previous hospital admissions and disease severity predict the use of antipsychotic combination treatment in patients with schizophrenia
    Albert Bolstad
    Department of Psychiatry Research, Diakonhjemmet Hospital, P O Box 85 Vinderen, Oslo 0319, Norway
    BMC Psychiatry 11:126. 2011
  7. pmc Apathy is associated with executive functioning in first episode psychosis
    Ann Faerden
    Ulleval University Hospital, 0407 Oslo, Norway
    BMC Psychiatry 9:1. 2009
  8. pmc The estrogen hypothesis of schizophrenia implicates glucose metabolism: association study in three independent samples
    Line Olsen
    Research Institute of Biological Psychiatry, Sct, Hans Hospital, DK 4000 Roskilde, Denmark
    BMC Med Genet 9:39. 2008
  9. doi request reprint Common sequence variants in the major histocompatibility complex region associate with cerebral ventricular size in schizophrenia
    Ingrid Agartz
    Institute of Clinical Medicine, Department of Biostatistics, University of Oslo, Oslo, Norway
    Biol Psychiatry 70:696-8. 2011
  10. doi request reprint An exploratory model for G x E interaction on hippocampal volume in schizophrenia; obstetric complications and hypoxia-related genes
    Unn Kristin Haukvik
    Department of Clinical Medicine, section Vinderen, University of Oslo, Norway
    Prog Neuropsychopharmacol Biol Psychiatry 34:1259-65. 2010

Detail Information

Publications100

  1. ncbi request reprint MR volumetry during acute alcohol withdrawal and abstinence: a descriptive study
    Ingrid Agartz
    Karolinska Institutet, Department of Clinical Neuroscience, Clinical Alcohol and Drug Addiction Research Section and Human Brain Informatics, Psychiatry Section, Karolinska Hospital, Stockholm SE 171 76, Sweden
    Alcohol Alcohol 38:71-8. 2003
    ....
  2. ncbi request reprint Brain-derived neurotrophic factor gene (BDNF) variants and schizophrenia: an association study
    Erik G Jonsson
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, SE 171 76 Stockholm, Sweden
    Prog Neuropsychopharmacol Biol Psychiatry 30:924-33. 2006
    ..Thus, the BDNF gene may confer susceptibility to schizophrenia. Additional studies are warranted to shed further light on this possibility...
  3. ncbi request reprint BDNF gene variants and brain morphology in schizophrenia
    Ingrid Agartz
    Department of Clinical Neuroscience, Human Brain Informatics, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 141:513-23. 2006
    ..Trends for associations between several polymorphisms/haplotype estimates and MRI volumes were found. BDNF gene variation may influence brain morphology. The effects may be different in patients with schizophrenia and healthy subjects...
  4. doi request reprint Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene
    Anna K Kähler
    TOP Project, Institute of Psychiatry, University of Oslo, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 147:1089-100. 2008
    ....
  5. doi request reprint A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample
    Srdjan Djurovic
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    J Affect Disord 126:312-6. 2010
    ..In the present study we investigated genetic variants associated with bipolar disorder in a homogenous Norwegian sample, and potential genetic overlap with schizophrenia, using the Affymetrix 6.0 array...
  6. pmc Previous hospital admissions and disease severity predict the use of antipsychotic combination treatment in patients with schizophrenia
    Albert Bolstad
    Department of Psychiatry Research, Diakonhjemmet Hospital, P O Box 85 Vinderen, Oslo 0319, Norway
    BMC Psychiatry 11:126. 2011
    ....
  7. pmc Apathy is associated with executive functioning in first episode psychosis
    Ann Faerden
    Ulleval University Hospital, 0407 Oslo, Norway
    BMC Psychiatry 9:1. 2009
    ....
  8. pmc The estrogen hypothesis of schizophrenia implicates glucose metabolism: association study in three independent samples
    Line Olsen
    Research Institute of Biological Psychiatry, Sct, Hans Hospital, DK 4000 Roskilde, Denmark
    BMC Med Genet 9:39. 2008
    ..Thus, we tested the hypothesis that variants of the glycolytic genes are associated with schizophrenia or at least with gender-associated aspects of the illness...
  9. doi request reprint Common sequence variants in the major histocompatibility complex region associate with cerebral ventricular size in schizophrenia
    Ingrid Agartz
    Institute of Clinical Medicine, Department of Biostatistics, University of Oslo, Oslo, Norway
    Biol Psychiatry 70:696-8. 2011
    ..3-22.1 has been implicated in the development of schizophrenia...
  10. doi request reprint An exploratory model for G x E interaction on hippocampal volume in schizophrenia; obstetric complications and hypoxia-related genes
    Unn Kristin Haukvik
    Department of Clinical Medicine, section Vinderen, University of Oslo, Norway
    Prog Neuropsychopharmacol Biol Psychiatry 34:1259-65. 2010
    ....
  11. doi request reprint Dystrobrevin-binding protein 1 gene (DTNBP1) variants associated with cerebrospinal fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in healthy volunteers
    Dimitrios Andreou
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, SE 17176 Stockholm, Sweden
    Eur Neuropsychopharmacol 21:700-4. 2011
    ..The results suggest that genetic variation in DTNBP1 gene affects the regulation of dopamine and serotonin turnover in the central nervous system of healthy volunteers...
  12. doi request reprint Subcortical brain volumes relate to neurocognition in schizophrenia and bipolar disorder and healthy controls
    Cecilie B Hartberg
    Institute of Clinical Medicine, Psychiatry Section, University of Oslo, Norway
    Prog Neuropsychopharmacol Biol Psychiatry 35:1122-30. 2011
    ..It is unknown whether relationships between subcortical volumes and neurocognitive performance are similar or different between schizophrenia and bipolar disorder...
  13. doi request reprint Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area
    Anna K Kähler
    Institute of Psychiatry, University of Oslo, Oslo University Hospital Ulleval, Norway
    Biol Psychiatry 69:90-6. 2011
    ..Extracellular matrix structures called perineuronal nets, condensed around subsets of neurons and proximal dendrites during brain maturation, regulate synaptic transmission and plasticity...
  14. doi request reprint Dysbindin and d-amino-acid-oxidase gene polymorphisms associated with positive and negative symptoms in schizophrenia
    Katrine V Wirgenes
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Neuropsychobiology 60:31-6. 2009
    ....
  15. doi request reprint DTNBP1, NRG1, DAOA, DAO and GRM3 polymorphisms and schizophrenia: an association study
    Erik G Jonsson
    HUBIN project, Department of Clinical Neuroscience, Karolinska Institutet and Hospital, Stockholm, Sweden
    Neuropsychobiology 59:142-50. 2009
    ....
  16. doi request reprint Two methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms, schizophrenia and bipolar disorder: an association study
    Erik G Jonsson
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 147:976-82. 2008
    ..However, when combined with previous studies in meta-analyses there is still evidence for association between the MTHFR C677T polymorphism and schizophrenia. Additional studies are warranted to shed further light on these relationships...
  17. doi request reprint ZNF804A and cortical thickness in schizophrenia and bipolar disorder
    Orjan Bergmann
    KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    Psychiatry Res 212:154-7. 2013
    ..Results show no significant associations...
  18. doi request reprint The tryptophan hydroxylase 1 (TPH1) gene, schizophrenia susceptibility, and suicidal behavior: a multi-centre case-control study and meta-analysis
    Peter Saetre
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 153:387-96. 2010
    ....
  19. doi request reprint Brain-derived neurotrophic factor gene variation influences cerebrospinal fluid 3-methoxy-4-hydroxyphenylglycol concentrations in healthy volunteers
    Erik G Jonsson
    Department of Clinical Neuroscience, Karolinska Institute and Hospital, Stockholm, Sweden
    J Neural Transm 115:1695-9. 2008
    ..01). The results suggest that BDNF gene variation participates in regulation of norepinephrine turnover rates in the central nervous system of human subjects...
  20. doi request reprint Investigating relationships between cortical thickness and cognitive performance in patients with schizophrenia and healthy adults
    Cecilie Bhandari Hartberg
    Institute of Psychiatry, section Vinderen, University of Oslo, Oslo, Norway
    Psychiatry Res 182:123-33. 2010
    ....
  21. pmc Association between a genetic variant in the serotonin transporter gene (SLC6A4) and suicidal behavior in patients with schizophrenia
    Eva Lindholm Carlström
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, Stockholm, Sweden
    Behav Brain Funct 8:24. 2012
    ..In this study, we wanted to elucidate whether SLC6A4 variations is involved in attempted suicide among patients with schizophrenia in a Scandinavian case-control sample...
  22. doi request reprint Interleukin 1 receptor antagonist and soluble tumor necrosis factor receptor 1 are associated with general severity and psychotic symptoms in schizophrenia and bipolar disorder
    Sigrun Hope
    KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    Schizophr Res 145:36-42. 2013
    ..We investigated if elevated inflammation was associated with disease severity (trait) or current symptom level (state), comparing psychotic with general characteristics...
  23. pmc D-amino acid oxidase activator gene (DAOA) variation affects cerebrospinal fluid homovanillic acid concentrations in healthy Caucasians
    Dimitrios Andreou
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Eur Arch Psychiatry Clin Neurosci 262:549-56. 2012
    ....
  24. doi request reprint Association analysis of ANK3 gene variants in nordic bipolar disorder and schizophrenia case-control samples
    Martin Tesli
    Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 156:969-74. 2011
    ..These results further support that ANK3 is a susceptibility gene specific to BD and that more than one risk locus is involved...
  25. doi request reprint Genome-wide study identifies PTPRO and WDR72 and FOXQ1-SUMO1P1 interaction associated with neurocognitive function
    Marissa Leblanc
    Epi Gen, Institute of Clinical Medicine, Akershus University Hospital, University of Oslo, Oslo, Norway
    J Psychiatr Res 46:271-8. 2012
    ..We performed a genome-wide association study (GWAS) to identify genes associated with neurocognition...
  26. doi request reprint Association between a disrupted-in-schizophrenia 1 (DISC1) single nucleotide polymorphism and schizophrenia in a combined Scandinavian case-control sample
    Peter Saetre
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, SE 171 76 Stockholm, Sweden
    Schizophr Res 106:237-41. 2008
    ....
  27. doi request reprint BDNF val66met modulates the association between childhood trauma, cognitive and brain abnormalities in psychoses
    Monica Aas
    Institute of Clinical Medicine, University of Oslo, Norway Psychosis Research Unit, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway Electronic address
    Prog Neuropsychopharmacol Biol Psychiatry 46:181-8. 2013
    ....
  28. doi request reprint Effect of DISC1 SNPs on brain structure in healthy controls and patients with a history of psychosis
    Anna K Kähler
    Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 159:722-30. 2012
    ..In conclusion, DISC1 SNPs might impact brain structural variation, possibly differently in psychosis patients versus controls, but independent replication will be needed to confirm our findings...
  29. doi request reprint Cortical volume, surface area, and thickness in schizophrenia and bipolar disorder
    Lars M Rimol
    Division of Mental Health and Addiction, Institute of Clinical Medicine, University of Oslo, Norway
    Biol Psychiatry 71:552-60. 2012
    ....
  30. doi request reprint Brain-derived neurotrophic factor polymorphisms and frontal cortex morphology in schizophrenia
    Katarina Varnas
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, SE 171 76 Stockholm, Sweden
    Psychiatr Genet 18:177-83. 2008
    ..To investigate associations between brain-derived neurotrophic factor (BDNF) gene polymorphisms and regional frontal cortical thickness and volume in patients with schizophrenia and healthy control participants...
  31. doi request reprint Catechol O-methyltransferase variants and cognitive performance in schizophrenia and bipolar disorder versus controls
    Katrine V Wirgenes
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Schizophr Res 122:31-7. 2010
    ..However, the results have been inconsistent and there are few studies addressing other COMT single nucleotide polymorphisms (SNPs)...
  32. pmc Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age at onset of schizophrenia: no consistent evidence for an association in the Nordic population
    Peter Saetre
    Department of Clinical Neuroscience, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 159:981-6. 2012
    ..The present results do not suggest that the investigated MTHFR polymorphism has any significant influence on age at onset of schizophrenia in the Nordic population...
  33. doi request reprint Is cognitive impairment following early life stress in severe mental disorders based on specific or general cognitive functioning?
    Monica Aas
    Institute of Clinical Medicine, University of Oslo, Norway
    Psychiatry Res 198:495-500. 2012
    ..Moreover, these dysfunctions seem to be driven by underlying deficits in general cognitive tasks as measured by the WASI...
  34. pmc Serotonin transporter gene polymorphism, childhood trauma, and cognition in patients with psychotic disorders
    Monica Aas
    Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    Schizophr Bull 38:15-22. 2012
    ..We hypothesize that 5-HTTLPR variations and long-term effects of childhood trauma interact and contribute to some of the variation in cognitive dysfunction seen in patients with psychotic disorders...
  35. pmc Increased sensitivity to effects of normal aging and Alzheimer's disease on cortical thickness by adjustment for local variability in gray/white contrast: a multi-sample MRI study
    Lars T Westlye
    Center for the Study of Human Cognition, Department of Psychology, University of Oslo, Oslo, Norway
    Neuroimage 47:1545-57. 2009
    ..In sum, the findings indicate that adjusting for contrast can increase the sensitivity of MR morphometry to variables of interest...
  36. doi request reprint Tryptophan hydroxylase gene 1 (TPH1) variants associated with cerebrospinal fluid 5-hydroxyindole acetic acid and homovanillic acid concentrations in healthy volunteers
    Dimitrios Andreou
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, SE 171 76 Stockholm, Sweden
    Psychiatry Res 180:63-7. 2010
    ..The results suggest that TPH1 gene variation participates in the regulation of serotonin and dopamine turnover rates in the central nervous system of healthy human subjects...
  37. pmc Consistent neuroanatomical age-related volume differences across multiple samples
    Kristine B Walhovd
    Center for the Study of Human Cognition, Department of Psychology, University of Oslo, Norway
    Neurobiol Aging 32:916-32. 2011
    ..Healthy aging appears associated with more widespread and consistent age-related neuroanatomical volume differences than previously believed...
  38. doi request reprint Intron 12 in NTRK3 is associated with bipolar disorder
    Lavinia Athanasiu
    Department of Psychiatry, Oslo University Hospital Ulleval, Oslo, Norway
    Psychiatry Res 185:358-62. 2011
    ....
  39. doi request reprint Association study of PDE4B gene variants in Scandinavian schizophrenia and bipolar disorder multicenter case-control samples
    Anna K Kähler
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 153:86-96. 2010
    ..Further studies are needed to evaluate the implicated PDE4B region of interest, for potential involvement in SZ and BP susceptibility...
  40. ncbi request reprint Potential genetic variants in schizophrenia: a Bayesian analysis
    Hakan Hall
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    World J Biol Psychiatry 8:12-22. 2007
    ..The results indicate that the Bayesian statistical method gives additional possibilities in the search for risk factors for schizophrenia or other complex disorders...
  41. doi request reprint Association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age of onset in schizophrenia
    Maria Vares
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 153:610-8. 2010
    ..008). The MTHFR C677T polymorphism may play a role as a modifying factor for age of onset in schizophrenia...
  42. doi request reprint The neural correlates of cognitive control in bipolar I disorder: an fMRI study of medial frontal cortex activation during a Go/No-go task
    Audun Welander-Vatn
    Institute of Clinical Medicine, Section of Psychiatry, University of Oslo, 0318 Oslo, Norway
    Neurosci Lett 549:51-6. 2013
    ..Although the patients display some deviances in behavioural measures, this study reveals no significant differences between BD I subjects and healthy controls in recruitment of the medial frontal cortex during a Go/No-go task. ..
  43. pmc CACNA1C risk variant and amygdala activity in bipolar disorder, schizophrenia and healthy controls
    Martin Tesli
    Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    PLoS ONE 8:e56970. 2013
    ....
  44. doi request reprint Cardiovascular risk factors during second generation antipsychotic treatment are associated with increased C-reactive protein
    Ingrid Dieset
    Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    Schizophr Res 140:169-74. 2012
    ..We investigated whether there is a relationship between CVD risk factors and inflammation in schizophrenia or bipolar disorder, and if second generation antipsychotics (SGA) interact...
  45. pmc Minute effects of sex on the aging brain: a multisample magnetic resonance imaging study of healthy aging and Alzheimer's disease
    Anders M Fjell
    Center for the Study of Human Cognition, Department of Psychology, University of Oslo, 0317 Oslo, Norway
    J Neurosci 29:8774-83. 2009
    ..Analyses of the AD sample showed no interactions between sex and age for any brain region. We conclude that sex has negligible effects on the age slope of brain volumes both in healthy participants and in AD...
  46. doi request reprint Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE)
    Srdjan Djurovic
    Institute of Psychiatry, University of Oslo, Norway
    Psychiatry Res 168:256-8. 2009
    ..We report, for the first time, a possible involvement of MCTP2 as a potential novel susceptibility gene for schizophrenia...
  47. ncbi request reprint Regional thinning of the cerebral cortex in schizophrenia: effects of diagnosis, age and antipsychotic medication
    Ragnar Nesvåg
    Department of Psychiatric Research, Diakonhjemmet Hospital, and Institute of Psychiatry, University of Oslo, Norway
    Schizophr Res 98:16-28. 2008
    ..The lack of significant influence from antipsychotic medication supports that regional cortical thinning is an inherent feature of the neurobiological disease process in schizophrenia...
  48. doi request reprint The use of screening instruments for detecting alcohol and other drug use disorders in first-episode psychosis
    Ragnar Nesvåg
    Department of Psychiatry, Diakonhjemmet Hospital, Oslo, Norway
    Psychiatry Res 177:228-34. 2010
    ..The results of this study suggest that AUDIT and DUDIT are powerful screening instruments for detecting alcohol and other drug use disorders in patients with first-episode psychosis...
  49. doi request reprint Depression and depressive symptoms in first episode psychosis
    Kristin Lie Romm
    Department of Psychiatry, Oslo University Hospital, Ulleval, Oslo, Norway
    J Nerv Ment Dis 198:67-71. 2010
    ..Thus depressive symptoms are frequent among FEPP, with indications of gender specific differences in patient characteristics that might imply different approaches to treatment...
  50. pmc Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort
    Lavinia Athanasiu
    Institute of Psychiatry, University of Oslo, P O 1130, Blindern, N 0318 Oslo, Norway
    J Psychiatr Res 44:748-53. 2010
    ..The association of ANK3 with schizophrenia is intriguing in light of recent associations of ANK3 with bipolar disorder, thereby supporting the hypothesis of an overlap in genetic susceptibility between these psychopathological entities...
  51. doi request reprint High prevalence of childhood trauma in patients with schizophrenia spectrum and affective disorder
    Sara Larsson
    Department of Research and Development, Clinic of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    Compr Psychiatry 54:123-7. 2013
    ....
  52. doi request reprint Up-regulation of NOTCH4 gene expression in bipolar disorder
    Ingrid Dieset
    Division of Mental Health and Addiction, Oslo University Hospital Ulleval, Oslo, Norway
    Am J Psychiatry 169:1292-300. 2012
    ..The authors investigated the NOTCH4 gene expression in individuals with bipolar disorder and schizophrenia relative to healthy comparison subjects and identified putative expression quantitative trait loci in and around the NOTCH4 gene...
  53. doi request reprint Associations between variants near a monoaminergic pathways gene (PHOX2B) and amygdala reactivity: a genome-wide functional imaging study
    Olga Therese Ousdal
    Oslo University Hospital, Oslo, Norway
    Twin Res Hum Genet 15:273-85. 2012
    ....
  54. doi request reprint Genome-wide association study identifies genetic loci associated with body mass index and high density lipoprotein-cholesterol levels during psychopharmacological treatment - a cross-sectional naturalistic study
    Lavinia Athanasiu
    Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    Psychiatry Res 197:327-36. 2012
    ..This deserves to be replicated in additional populations to provide more evidence for molecular genetic mechanisms of side effects during psychopharmacological treatment...
  55. doi request reprint Evidence for a possible association of neurotrophin receptor (NTRK-3) gene polymorphisms with hippocampal function and schizophrenia
    Mona K Otnaess
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Neurobiol Dis 34:518-24. 2009
    ..The present results, although not robust, suggest that the NTRK-3 gene influences hippocampal function and may modify the risk for schizophrenia...
  56. doi request reprint Association analysis of PALB2 and BRCA2 in bipolar disorder and schizophrenia in a scandinavian case-control sample
    Martin Tesli
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Am J Med Genet B Neuropsychiatr Genet 153:1276-82. 2010
    ..Our findings support PALB2 and BRCA2 as risk genes specifically for BD, and suggest that altered DNA repair related to neurogenesis may be involved in BD pathophysiology. © 2010 Wiley-Liss, Inc...
  57. pmc Patterns of childhood adverse events are associated with clinical characteristics of bipolar disorder
    Sara Larsson
    Institute of Clinical Medicine, University of Oslo, Oslo, Norway
    BMC Psychiatry 13:97. 2013
    ....
  58. doi request reprint Neurocognitive function in long-term treated schizophrenia: a five-year follow-up study
    Maria Ekerholm
    Department of Clinical Neuroscience, Karolinska Institutet and Hospital, SE 171 76 Stockholm, Sweden
    Psychiatry Res 200:144-52. 2012
    ..5 years in patients with long-term treated schizophrenia, in line with previous scientific research. The authors discuss the impact of age and education and limitations of the study...
  59. pmc Kynurenine 3-monooxygenase polymorphisms: relevance for kynurenic acid synthesis in patients with schizophrenia and healthy controls
    Maria Holtze
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
    J Psychiatry Neurosci 37:53-7. 2012
    ..This compound is an end-metabolite of the kynurenine pathway, and its formation indirectly depends on the activity of kynurenine 3-monooxygenase (KMO), the enzyme converting kynurenine to 3-hydroxykynurenine...
  60. doi request reprint Self-harm in patients with schizophrenia spectrum disorders
    Erlend Mork
    National Centre for SuicideResearch and Prevention, Institute ofClinical Medicine, University of Oslo, Oslo, Norway
    Arch Suicide Res 16:111-23. 2012
    ..We conclude that while self-harm in patients with schizophrenia spectrum disorders is highly prevalent in both genders, risk factors in men and women differ in several important ways...
  61. ncbi request reprint Effects of alcohol consumption and antipsychotic medication on brain morphology in schizophrenia
    Ragnar Nesvåg
    Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway
    Schizophr Res 90:52-61. 2007
    ..This study demonstrates that alcohol consumption is an important factor for variation in WM volumes, and this effect should be taken into account in all studies evaluating brain volumes from MR images...
  62. ncbi request reprint Grey and white matter proportional relationships in the cerebellar vermis altered in schizophrenia
    Glenn Lawyer
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Cerebellum 8:52-60. 2009
    ..Tissue class volumes in the cerebellar vermis were strongly interrelated in controls. These relationships were disturbed in patients with schizophrenia...
  63. doi request reprint No effect of obstetric complications on basal ganglia volumes in schizophrenia
    Unn Kristin Haukvik
    Institute of Psychiatry, section Vinderen, University of Oslo, P O Box 85 Vinderen, N 0319 Oslo, Norway
    Prog Neuropsychopharmacol Biol Psychiatry 34:619-23. 2010
    ..This is the first study to explore if there is a relationship between OCs and basal ganglia volume in schizophrenia...
  64. pmc Amphetamine dependence and co-morbid alcohol abuse: associations to brain cortical thickness
    Glenn Lawyer
    Department of Psychiatry, University of Oslo, Norway
    BMC Pharmacol 10:5. 2010
    ..In addition to contrasting patients with controls, a number of analyses sought to identify possible confounding effects from alcohol...
  65. doi request reprint Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and age of onset in schizophrenia: a combined analysis of independent samples
    Peter Saetre
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 156:215-24. 2011
    ..The present results suggest that the investigated MTHFR polymorphisms do not influence age of onset in schizophrenia...
  66. ncbi request reprint Cerebellar volumes in men with schizophrenia and alcohol dependence
    Katarina Varnas
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Psychiatry Clin Neurosci 61:326-9. 2007
    ..The results provide indications for differential morphological abnormalities of the cerebellar vermis in patients with schizophrenia and alcohol dependence...
  67. doi request reprint Cortical thickness and subcortical volumes in schizophrenia and bipolar disorder
    Lars M Rimol
    Department of Psychiatry, section Vinderen, University of Oslo, Oslo, Norway
    Biol Psychiatry 68:41-50. 2010
    ..The purpose of this study was to compare cortical thickness and subcortical volumes in schizophrenia and bipolar disorder, to assess differences and similarities in cortical and subcortical brain structure...
  68. doi request reprint The relationship between symptom severity and regional cortical and grey matter volumes in schizophrenia
    Ragnar Nesvåg
    Institute of Psychiatry, University of Oslo, P O Box 85 Vinderen, 0319 Oslo, Norway
    Prog Neuropsychopharmacol Biol Psychiatry 33:482-90. 2009
    ..To investigate the relationship between symptom severity and cortical and grey matter volumes in schizophrenia...
  69. doi request reprint Apathy and functioning in first-episode psychosis
    Ann Faerden
    Department of Psychiatry, Ulleval University Hospital, Oslo, Norway
    Psychiatr Serv 60:1495-503. 2009
    ....
  70. ncbi request reprint Pathway analysis of genetic markers associated with a functional MRI faces paradigm implicates polymorphisms in calcium responsive pathways
    Morten Mattingsdal
    Research Unit, Sørlandet Hospital, Kristiansand, Norway
    Neuroimage 70:143-9. 2013
    ..These findings suggest that pathway analysis of GWAS results derived from principal component analysis of fMRI data is a promising method, to our knowledge, not previously described...
  71. doi request reprint Increased systemic cortisol metabolism in patients with schizophrenia and bipolar disorder: a mechanism for increased stress vulnerability?
    Nils Eiel Steen
    Section for Psychosis Research, Clinic of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
    J Clin Psychiatry 72:1515-21. 2011
    ....
  72. pmc Morphological correlates to cognitive dysfunction in schizophrenia as studied with Bayesian regression
    Glenn Laywer
    Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden
    BMC Psychiatry 6:31. 2006
    ..This work explored a model encompassing all of these possibilities to identify the strongest morphological relationships to cognitive skill in schizophrenia...
  73. doi request reprint Investigating possible subtypes of schizophrenia patients and controls based on brain cortical thickness
    Glenn Lawyer
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Psychiatry Res 164:254-64. 2008
    ..The study found no subtypes specific to patients. It suggested, however, that associations between abnormally thin cortex and schizophrenia are more widespread than shown by previously published results based on significance testing...
  74. doi request reprint Local and covariate-modulated false discovery rates applied in neuroimaging
    Glenn Lawyer
    Department of Psychiatry, University of Oslo, Oslo, Norway
    Neuroimage 47:213-9. 2009
    ..The increased statistical precision from more accurate models of the distribution of the test statistic demonstrates the potential of these methods for neuroimaging and suggests the possibility to test novel hypothesis...
  75. ncbi request reprint Frontal and temporal volume size of grey and white matter in patients with schizophrenia: an MRI parcellation study
    Gaku Okugawa
    Department of Clinical Neuroscience, Human Brain Informatics, Karolinska Institutet, Stockholm 171 76, Sweden
    Eur Arch Psychiatry Clin Neurosci 257:304-7. 2007
    ..Schizophrenic patients had a greater CSF volume in the frontal and temporal lobes. These results suggest that volume reduction in the cerebrum is prominent in the frontal and temporal lobes in both men and women with schizophrenia...
  76. doi request reprint Cerebral cortical thickness and a history of obstetric complications in schizophrenia
    Unn Kristin Haukvik
    Institute of Psychiatry, University of Oslo, P O Box 85 Vinderen, N 0319 Oslo, Norway
    J Psychiatr Res 43:1287-93. 2009
    ....
  77. doi request reprint No altered dorsal anterior cingulate activation in bipolar II disorder patients during a Go/No-go task: an fMRI study
    Audun S Welander-Vatn
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    Bipolar Disord 11:270-9. 2009
    ..The aim of this study was to investigate whether patients with BD II showed decreased activation in the dorsal anterior cingulate cortex (dACC) as compared to healthy controls when performing a task sensitive to impulsivity...
  78. ncbi request reprint Selective reduction of the posterior superior vermis in men with chronic schizophrenia
    Gaku Okugawa
    Department of Clinical Neuroscience, Human Brain Informatics Center HUBIN, Karolinska Institute and Hospital, SE 171 76 Stockholm, Sweden
    Schizophr Res 55:61-7. 2002
    ..The findings support the view that within the cerebellum the posterior superior vermis may be selectively reduced in men with chronic schizophrenia...
  79. ncbi request reprint Altered white matter/gray matter proportions in the striatum of patients with schizophrenia: a volumetric MRI study
    Chiharu Tamagaki
    Human Brain Informatics, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Am J Psychiatry 162:2315-21. 2005
    ..Anatomical structures of the striatum were studied in 58 patients with schizophrenia and 56 healthy comparison subjects of both genders matched for age and handedness...
  80. ncbi request reprint Age at onset of bipolar disorder in a Norwegian catchment area sample
    Sara Larsson
    Institute of Psychiatry, University of Oslo, Oslo, Norway
    J Affect Disord 124:174-7. 2010
    ..In addition, we examined whether age at onset influenced on time to first treatment, and if patient characteristics related to illness severity influenced age at onset...
  81. ncbi request reprint Assessing apathy: the use of the Apathy Evaluation Scale in first episode psychosis
    Ann Faerden
    Section for Psychosis Research, Division of Psychiatry, Building 49, Ulleval University Hospital, Krikeveien 166, 0407 Oslo, Norway
    Eur Psychiatry 23:33-9. 2008
    ..The main aims of this study were to examine the psychometric properties of the AES-C and its relationship to the Positive and Negative Syndrome Scale (PANSS)...
  82. doi request reprint Apathy in first episode psychosis patients: one year follow up
    Ann Faerden
    Oslo University Hospital, Ulleval, 0407 Oslo, Norway
    Schizophr Res 116:20-6. 2010
    ....
  83. pmc Excessive substance use in bipolar disorder is associated with impaired functioning rather than clinical characteristics, a descriptive study
    Trine V Lagerberg
    Section for Psychosis Research, Oslo University Hospital, Bygg 49, Kirkevn, 166 N 0407 Oslo, Norway
    BMC Psychiatry 10:9. 2010
    ....
  84. doi request reprint Suicidality in first episode psychosis is associated with insight and negative beliefs about psychosis
    Elizabeth A Barrett
    Department of Mental Health and Addiction, Oslo University Hospital, 0424 Oslo, Norway
    Schizophr Res 123:257-62. 2010
    ....
  85. doi request reprint Neurocognitive functioning and suicidality in schizophrenia spectrum disorders
    Elizabeth A Barrett
    Department of Mental Health and Addiction, Oslo University Hospital, 0424 Oslo, Norway
    Compr Psychiatry 52:156-63. 2011
    ....
  86. doi request reprint [Do obstetric complications increase the risk of schizophrenia?]
    Unn Kristin Haukvik
    Institutt for psykiatri, Universitetet i Oslo, Postboks 85 Vinderen, 0319 Oslo, Norway
    Tidsskr Nor Laegeforen 130:270-2. 2010
    ..The purpose of this article is to provide an overview of research on obstetric complications as risk factors for schizophrenia...
  87. doi request reprint Suicidality before and in the early phases of first episode psychosis
    Elizabeth A Barrett
    Department of Mental Health, Oslo University Hospital, 0514 Oslo, Norway
    Schizophr Res 119:11-7. 2010
    ..This study explored the prevalence and characteristics of suicidality in patients with a first episode of psychosis (FEP) in two time intervals: 1) prior to study entry and 2) explicitly in the period of untreated psychosis...
  88. doi request reprint Sex-specific cortisol levels in bipolar disorder and schizophrenia during mental challenge--relationship to clinical characteristics and medication
    Nils Eiel Steen
    Psychosis Research Unit, Division of Mental Health and Addiction, Oslo University Hospital, Ulleval Hospital, P O Box 4956 Nydalen, 0424 Oslo, Norway
    Prog Neuropsychopharmacol Biol Psychiatry 35:1100-7. 2011
    ....
  89. ncbi request reprint Similar immune profile in bipolar disorder and schizophrenia: selective increase in soluble tumor necrosis factor receptor I and von Willebrand factor
    Sigrun Hope
    Department of Psychiatry, Østfold Hospital, Eidsberg, Norway
    Bipolar Disord 11:726-34. 2009
    ....
  90. pmc Osteoprotegerin levels in patients with severe mental disorders
    Sigrun Hope
    Department of Psychiatry, Østfold Hospital, Fredrikstad, Norway
    J Psychiatry Neurosci 35:304-10. 2010
    ..In the present study, we investigated whether osteoprotegerin (OPG), a member of the tumour necrosis factor receptor family involved in calcification and inflammation, is elevated in patients with severe mental disorders...
  91. pmc High consistency of regional cortical thinning in aging across multiple samples
    Anders M Fjell
    Center for the Study of Human Cognition, Department of Psychology, University of Oslo, Olso 0317, Norway
    Cereb Cortex 19:2001-12. 2009
    ..The inferior temporal lobe and anterior cingulate cortices were relatively less affected by age. The results are discussed in relation to leading theories of cognitive aging...
  92. doi request reprint Affective symptoms are associated with markers of inflammation and immune activation in bipolar disorders but not in schizophrenia
    Sigrun Hope
    Department of Psychiatry, Østfold Hospital, Fredrikstad, Norway
    J Psychiatr Res 45:1608-16. 2011
    ..We aimed to determine if immune markers that consistently have been reported elevated in BP were associated with depressive and manic symptoms, and if this was specific for BP...
  93. ncbi request reprint Smaller cerebellar vermis but not hemisphere volumes in patients with chronic schizophrenia
    Gaku Okugawa
    Department of Clinical Neuroscience, Human Brain Infomatics Center HUBIN, Karolinska Institute and Hospital, Stockholm, Sweden
    Am J Psychiatry 160:1614-7. 2003
    ..In this study, they tested whether posterior superior vermis reduction would be seen in a larger group of schizophrenia patients, both male and female...
  94. ncbi request reprint Reduced grey and white matter volumes in the temporal lobe of male patients with chronic schizophrenia
    Gaku Okugawa
    Department of Clinical Neuroscience, Human Brain Informatics HUBIN, Psychiatry Section, Karolinska Institute and Hospital, 17176 Stockholm, Sweden
    Eur Arch Psychiatry Clin Neurosci 252:120-3. 2002
    ..The volume of white matter in the whole brain also appears to be reduced. Among the different brains regions, grey matter reduction was significant only in the temporal region...
  95. ncbi request reprint Morphometric and psychometric comparisons between non-substance-abusing patients with posttraumatic stress disorder and normal controls
    Reza Emdad
    Karolinska Institute, and National Institute for Psychosocial Medicine, Stockholm, Sweden
    Psychother Psychosom 75:122-32. 2006
    ....
  96. ncbi request reprint A morphometric magnetic resonance method for measuring cranial, facial and brain characteristics for application to schizophrenia: part 1
    Karin M Henriksson
    Department of Psychiatric Epidemiology, University Hospital, Lund University, Barngatan 2, S 221 85, Lund, Sweden
    Psychiatry Res 147:173-86. 2006
    ..In a second article we will use this method to compare 3D craniofacial measurements and shape between schizophrenia patients and healthy controls...
  97. doi request reprint Craniofacial dysmorphology and cortical thickness in men with schizophrenia
    Brendan D Kelly
    Schizophr Res 103:322-3. 2008
  98. ncbi request reprint Is craniofacial dysmorpholgy correlated with structural brain anomalies in schizophrenia?
    Brendan D Kelly
    The Stanley Research Unit, Department of Adult Psychiatry, Hospitaller Order of St John of God, Cluain Mhuire Centre, Newtownpark Avenue, Blackrock, Co Dublin, Ireland
    Schizophr Res 80:349-55. 2005
    ..These findings suggest that craniofacial dysmorphology and anomalies of brain morphology may be associated with independent processes in the etiology of schizophrenia...
  99. ncbi request reprint Minor physical anomalies in schizophrenia: is age a confounding factor?
    Karin M Henriksson
    Psychol Med 38:154-6. 2008
  100. ncbi request reprint A pilot study of facial, cranial and brain MRI morphometry in men with schizophrenia: part 2
    Karin Maria Henriksson
    Unit of Psychiatric Epidemiology, Barngatan 2, University Hospital, Lund University, S 221 85, Lund, Sweden
    Psychiatry Res 147:187-95. 2006
    ..In contrast, none of the patient-control differences for the new "interior" (cranial-brain) distances reached statistical significance. These results need to be retested on a larger sample of both sexes...