S Tonstad

Summary

Country: Norway

Publications

  1. pmc Orlistat after initial dietary/behavioural treatment: changes in body weight and dietary maintenance in subjects with sleep related breathing disorders
    Mette Svendsen
    Preventive Cardiology, Oslo University Hospital, Ulleval Hospital, N 0407 Oslo, Norway
    Nutr J 10:21. 2011
  2. pmc Leisure time physical activity in middle age predicts the metabolic syndrome in old age: results of a 28-year follow-up of men in the Oslo study
    Ingar Holme
    Centre of Preventive Medicine, Ulleval University Hospital, 0407 Oslo, Norway
    BMC Public Health 7:154. 2007
  3. ncbi request reprint Effect of nurse counselling on metabolic risk factors in patients with mild hypertension: a randomised controlled trial
    Serena Tonstad
    Department of Preventive Cardiology, Ulleval University Hospital, Oslo, Norway
    Eur J Cardiovasc Nurs 6:160-4. 2007
  4. ncbi request reprint Smoking cessation efficacy and safety of varenicline, an alpha4beta2 nicotinic receptor partial agonist
    Serena Tonstad
    Department of Preventive Cardiology, Ulleval University Hospital, Oslo, Norway
    J Cardiovasc Nurs 21:433-6. 2006
  5. ncbi request reprint Rimonabant: a cannabinoid receptor blocker for the treatment of metabolic and cardiovascular risk factors
    Serena Tonstad
    Department of Preventive Cardiology, Ulleval University Hospital, N 0407 Oslo, Norway
    Nutr Metab Cardiovasc Dis 16:156-62. 2006
  6. ncbi request reprint Varenicline for smoking cessation
    Serena Tonstad
    Ulleval University Hospital, Department of Preventive Cardiology N 0407 Oslo, Norway
    Expert Rev Neurother 7:121-7. 2007
  7. ncbi request reprint Effect of maintenance therapy with varenicline on smoking cessation: a randomized controlled trial
    Serena Tonstad
    Department of Preventive Cardiology, Ulleval University Hospital, and University of Oslo, Oslo, Norway
    JAMA 296:64-71. 2006
  8. ncbi request reprint Do novel risk factors differ between men and women aged 18 to 39 years with a high risk of coronary heart disease?
    Serena Tonstad
    Department of Preventive Cardiology, Center for Preventive Medicine, Ulleval University Hospital, Oslo, Norway
    Metabolism 56:260-6. 2007
  9. ncbi request reprint [Nutritional status after surgical treatment of obesity]
    Serena Tonstad
    Avdeling for preventiv kardiologi, Ulleval universitetssykehus, 0407 Oslo
    Tidsskr Nor Laegeforen 127:50-3. 2007
  10. ncbi request reprint No effect of increased water intake on blood viscosity and cardiovascular risk factors
    Serena Tonstad
    Department of Preventive Cardiology, Ulleval University Hospital, N 0407 Oslo, Norway
    Br J Nutr 96:993-6. 2006

Detail Information

Publications105 found, 100 shown here

  1. pmc Orlistat after initial dietary/behavioural treatment: changes in body weight and dietary maintenance in subjects with sleep related breathing disorders
    Mette Svendsen
    Preventive Cardiology, Oslo University Hospital, Ulleval Hospital, N 0407 Oslo, Norway
    Nutr J 10:21. 2011
    ..Orlistat is a pharmacological agent that reduces the intestinal absorption of fat and may favour long-term weight maintenance...
  2. pmc Leisure time physical activity in middle age predicts the metabolic syndrome in old age: results of a 28-year follow-up of men in the Oslo study
    Ingar Holme
    Centre of Preventive Medicine, Ulleval University Hospital, 0407 Oslo, Norway
    BMC Public Health 7:154. 2007
    ....
  3. ncbi request reprint Effect of nurse counselling on metabolic risk factors in patients with mild hypertension: a randomised controlled trial
    Serena Tonstad
    Department of Preventive Cardiology, Ulleval University Hospital, Oslo, Norway
    Eur J Cardiovasc Nurs 6:160-4. 2007
    ..Hypertension often clusters with metabolic risk factors and its optimal treatment may involve a number of changes in lifestyle. Nurse-led care regarding lifestyle change may improve outcomes in cardiovascular disease prevention involving...
  4. ncbi request reprint Smoking cessation efficacy and safety of varenicline, an alpha4beta2 nicotinic receptor partial agonist
    Serena Tonstad
    Department of Preventive Cardiology, Ulleval University Hospital, Oslo, Norway
    J Cardiovasc Nurs 21:433-6. 2006
    ..Phase 3 studies have evaluated the effects of varenicline on inducing smoking cessation and maintaining smoking abstinence...
  5. ncbi request reprint Rimonabant: a cannabinoid receptor blocker for the treatment of metabolic and cardiovascular risk factors
    Serena Tonstad
    Department of Preventive Cardiology, Ulleval University Hospital, N 0407 Oslo, Norway
    Nutr Metab Cardiovasc Dis 16:156-62. 2006
    ..This review discusses the role of rimonabant, a cannabinoid receptor 1 blocker, which has undergone Phase III clinical testing, in the treatment of obesity and tobacco dependence...
  6. ncbi request reprint Varenicline for smoking cessation
    Serena Tonstad
    Ulleval University Hospital, Department of Preventive Cardiology N 0407 Oslo, Norway
    Expert Rev Neurother 7:121-7. 2007
    ..It has no contraindications except hypersensitivity and is well tolerated. This article reviews the available information on varenicline and discusses its clinical use...
  7. ncbi request reprint Effect of maintenance therapy with varenicline on smoking cessation: a randomized controlled trial
    Serena Tonstad
    Department of Preventive Cardiology, Ulleval University Hospital, and University of Oslo, Oslo, Norway
    JAMA 296:64-71. 2006
    ..The majority of cigarette smokers who achieve abstinence relapse within the first year and require many attempts before achieving permanent abstinence. Evidence to support pharmacological treatment for relapse prevention is insufficient...
  8. ncbi request reprint Do novel risk factors differ between men and women aged 18 to 39 years with a high risk of coronary heart disease?
    Serena Tonstad
    Department of Preventive Cardiology, Center for Preventive Medicine, Ulleval University Hospital, Oslo, Norway
    Metabolism 56:260-6. 2007
    ..Lifestyle factors including body mass index, dietary sucrose, smoking, and hormones were associated with levels of the markers independent of sex with body mass index being the most prominent factor...
  9. ncbi request reprint [Nutritional status after surgical treatment of obesity]
    Serena Tonstad
    Avdeling for preventiv kardiologi, Ulleval universitetssykehus, 0407 Oslo
    Tidsskr Nor Laegeforen 127:50-3. 2007
    ..Biliopancreatic bypass with duodenal switch is a treatment for morbid obesity that combines restriction of dietary intake with a high degree of malabsorption. The operation involves the risk of losing important nutritional elements...
  10. ncbi request reprint No effect of increased water intake on blood viscosity and cardiovascular risk factors
    Serena Tonstad
    Department of Preventive Cardiology, Ulleval University Hospital, N 0407 Oslo, Norway
    Br J Nutr 96:993-6. 2006
    ..In conclusion, a postulated protective effect of increased water or fluid intake is not explained by a change in blood viscosity and increased fluid intake does not influence CVD risk factors in the short term...
  11. ncbi request reprint Identifying obese women most at risk from cardiovascular disease
    S Tonstad
    Department of Preventive Cardiology, Center for Preventive Medicine, Ulleval University Hospital, Oslo, Norway
    Int J Obes (Lond) 31:S19-25; discussion S31-2. 2007
    ..Weight loss and lifestyle changes that have been shown to improve risk-factor profiles are crucial interventions and should be considered, even if standard risk calculators do not indicate an elevated cardiovascular risk...
  12. ncbi request reprint The dual peroxisome proliferator-activated receptor alpha/gamma agonist tesaglitazar further improves the lipid profile in dyslipidemic subjects treated with atorvastatin
    Serena Tonstad
    Department of Preventive Cardiology, Ulleval University Hospital, N 0407, Oslo, Norway
    Metabolism 56:1285-92. 2007
    ..In conclusion, the addition of tesaglitazar to a background of atorvastatin therapy further improved the dyslipidemia associated with insulin resistance...
  13. ncbi request reprint Determinants of control of high blood pressure. The Oslo Health Study 2000-2001
    Serena Tonstad
    Department of Preventive Cardiology, Preventive Medicine Clinic, Ulleval University Hospital, Oslo, Norway
    Blood Press 13:343-9. 2004
    ..To examine determinants of control of high blood pressure in Oslo, Norway...
  14. ncbi request reprint [Should children with familial hypercholesterolemia be treated with statins?]
    Serena Tonstad
    Avdeling for preventiv kardiologi, Ulleval universitetssykehus, Oslo, Norge
    Lakartidningen 101:3406. 2004
  15. ncbi request reprint Premature coronary heart disease, cigarette smoking, and the metabolic syndrome
    Serena Tonstad
    Department of Preventive Cardiology, Division of Medicine, Ulleval University Hospital, Oslo, Norway
    Am J Cardiol 96:1681-5. 2005
    ..004). These findings indicate that although smoking cessation is imperative for patients with premature CHD, the metabolic risks associated with overweight and obesity after cessation need to be addressed...
  16. ncbi request reprint Efficacy and safety of topiramate in the treatment of obese subjects with essential hypertension
    Serena Tonstad
    University of Oslo, Oslo, Norway
    Am J Cardiol 96:243-51. 2005
    ..In conclusion, topiramate produced clinically relevant effects in reducing body weight and BP, with generally mild to moderate adverse effects...
  17. ncbi request reprint Effect of lifestyle changes on atherogenic lipids and endothelial cell adhesion molecules in young adults with familial premature coronary heart disease
    Serena Tonstad
    Department of Preventive Cardiology, Center for Clinical Research, Ulleval University Hospital, Oslo, Norway
    Am J Cardiol 95:1187-91. 2005
    ..05 between groups). These findings indicate that dietary modification and smoking cessation are feasible in young adults with familial premature CHD and document novel mechanisms by which lifestyle modification may reduce CHD risk...
  18. ncbi request reprint [Drugs for smoking cessation]
    Serena Tonstad
    Avdeling for preventiv kardiologi, Klinikk for forebyggende medisin, Ulleval universitetssykehus, 0407 Oslo
    Tidsskr Nor Laegeforen 125:178-80. 2005
  19. ncbi request reprint Association between plasma total homocysteine and parental history of cardiovascular disease in children with familial hypercholesterolemia
    S Tonstad
    Lipid Clinic, Medical Department A, National Hospital, Oslo, Norway
    Circulation 96:1803-8. 1997
    ..Because individuals with familial hyperlipidemias have an exceptionally high risk of premature CVD, we explored the relationship between tHcy and parental history of CVD in children with familial hypercholesterolemia (FH)...
  20. ncbi request reprint Consumption of fruit and berries is inversely associated with carotid atherosclerosis in elderly men
    I Ellingsen
    Department of Preventive Cardiology, Ulleval University Hospital, N 0047 Oslo, Norway
    Br J Nutr 99:674-81. 2008
    ..5 % adjusted difference in mean IMT. These findings suggest that consumption of fruit and berries may be protective against carotid atherosclerosis in elderly men at high risk of CVD...
  21. ncbi request reprint Molecular genetics of familial hypercholesterolaemia in Norway
    T P Leren
    Department of Medical Genetics, Ulleval University Hospital, Norway
    J Intern Med 241:185-94. 1997
    ..To characterize mutations in the low density lipoprotein (LDL) receptor gene causing familial hypercholesterolaemia (FH) amongst Norwegian patients...
  22. ncbi request reprint A common missense mutation (C210G) in the LDL receptor gene among Norwegian familial hypercholesterolemia subjects
    H Sundvold
    Department of Medical Genetics, Ulleval University Hospital, Oslo, Norway
    Hum Mutat 7:70-1. 1996
  23. doi request reprint Plant sterols from rapeseed and tall oils: effects on lipids, fat-soluble vitamins and plant sterol concentrations
    E Heggen
    Department of Preventive Cardiology, Ullevaal University Hospital, Oslo, Norway
    Nutr Metab Cardiovasc Dis 20:258-65. 2010
    ..We evaluated the effects of plant sterols from rapeseed and tall oils on serum lipids, lipoproteins, fat-soluble vitamins and plant sterol concentrations...
  24. ncbi request reprint Undertreatment and overtreatment with statins: the Oslo Health Study 2000-2001
    S Tonstad
    Department of Preventive Cardiology, Preventive Medicine Clinic, Ulleval University Hospital, Oslo, Norway
    J Intern Med 255:494-502. 2004
    ..We examined the prevalence and factors associated with use of cholesterol-lowering statins in the population...
  25. pmc Low dose colestipol in adolescents with familial hypercholesterolaemia
    S Tonstad
    Medical Department A, National Hospital, Oslo, Norway
    Arch Dis Child 74:157-60. 1996
    ..Although low dose colestipol effectively reduces low density lipoprotein cholesterol levels, only a minority of adolescents adhered to the new formulation for one year. Folate and possibly vitamin D supplementation is recommended...
  26. ncbi request reprint Risk factors related to carotid intima-media thickness and plaque in children with familial hypercholesterolemia and control subjects
    S Tonstad
    Medical Department A, National Hospital, Oslo, Norway
    Arterioscler Thromb Vasc Biol 16:984-91. 1996
    ..B-mode ultrasonography may prove to be a useful tool in risk stratification of children with FH...
  27. ncbi request reprint Two novel missense mutations in the LDL receptor gene causing familial hypercholesterolemia
    K E Gundersen
    Department of Medical Genetics, Ulleval University Hospital, Oslo, Norway
    Clin Genet 49:85-7. 1996
    ..Based upon screening of 437 unrelated familial hypercholesterolemia heterozygotes, both D147Y and Q345R account for about 0.5% of the mutations causing familial hypercholesterolemia in Norway...
  28. ncbi request reprint A high risk score for coronary heart disease is associated with the metabolic syndrome in 40-year-old men and women
    Serena Tonstad
    Department of Preventive Cardiology, Ulleval University Hospital, Oslo, Norway
    J Cardiovasc Risk 10:129-35. 2003
    ..Guidelines recommend follow-up of people whose 10-year risk of coronary heart disease (CHD) is > 10%. We calculated CHD risk, number of risk factors and occurrence of the metabolic syndrome among screened 40-year-old men and women...
  29. doi request reprint Kiwifruit decreases blood pressure and whole-blood platelet aggregation in male smokers
    A Karlsen
    Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway
    J Hum Hypertens 27:126-30. 2013
    ..009 and P=0.034). No effects on these parameters were observed in the antioxidant-rich diet group. This study suggest that intake of kiwifruit may have beneficial effects on BP and platelet aggregation in male smokers...
  30. ncbi request reprint Effect of dietary and antismoking advice on the incidence of myocardial infarction: a 16-year follow-up of the Oslo Diet and Antismoking Study after its close
    I Holme
    Department of Epidemiology, Preventive Medicine Clinic, Ulleval University Hospital, N 407 Oslo, Norway
    Nutr Metab Cardiovasc Dis 16:330-8. 2006
    ..In an extended follow-up we studied the incidence of myocardial infarction (MI) 16 years after the end of the trial in the intervention and control groups...
  31. ncbi request reprint The effect of an increased intake of vegetables and fruit on weight loss, blood pressure and antioxidant defense in subjects with sleep related breathing disorders
    M Svendsen
    Department of Preventive Cardiology, Ulleval University Hospital, Oslo, Norway
    Eur J Clin Nutr 61:1301-11. 2007
    ..To assess the effect of an increased consumption of vegetables and fruit on body weight, risk factors for cardiovascular disease (CVD) and antioxidant defense in obese patients with sleep-related breathing disorders (SRBD)...
  32. ncbi request reprint Follow-up of diet and cardiovascular risk factors 20 years after cessation of intervention in the Oslo Diet and Antismoking Study
    I Ellingsen
    Department of Preventive Medicine, Ulleval University Hospital, Oslo, Norway
    Eur J Clin Nutr 60:378-85. 2006
    ..To test the long-term maintenance of lifestyle change, we examined diet and cardiovascular risk factors in subjects initially randomised to the control and intervention groups 20 years after cessation of the intervention...
  33. ncbi request reprint Dietary adherence in children with familial hypercholesterolemia
    S Tonstad
    Medical Department A, National Hospital, Oslo, Norway
    Am J Clin Nutr 65:1018-26. 1997
    ..We conclude that adherence to fat restriction among children treated for familial hypercholesterolemia is associated with increased micronutrient density, decreased energy density, and psychosocial factors that facilitate adherence...
  34. ncbi request reprint Action levels for obesity treatment in 40 to 42-y-old men and women compared with action levels for prevention of coronary heart disease
    S Tonstad
    Preventive Cardiology, Department of Medicine, Ulleval Hospital, Oslo, Norway
    Int J Obes Relat Metab Disord 25:1698-704. 2001
    ....
  35. ncbi request reprint Reduced expression of endothelial cell markers after 1 year treatment with simvastatin and atorvastatin in patients with coronary heart disease
    Ingebjørg Seljeflot
    Center for Clinical Research, Ulleval University Hospital, Oslo, Norway
    Atherosclerosis 162:179-85. 2002
    ....
  36. ncbi request reprint Use of progestogen-only contraceptives/medications and lipid parameters in women age 40 to 42 years: results of a population-based cross-sectional Norwegian Survey
    Sidsel Graff-Iversen
    National Health Screening Service, Oslo, Norway
    Contraception 66:7-13. 2002
    ..Use of the IUD with levonorgestrel was also linked with a decreased risk of high serum triglycerides and of high non-HDL-cholesterol concentrations and a total/HDL-cholesterol ratio similar to that of nonusers of hormones...
  37. ncbi request reprint Effect of smoking cessation on markers of inflammation and endothelial cell activation among individuals with high risk for cardiovascular disease
    B Halvorsen
    Institute for Internal Medicine Research, University of Oslo, Oslo, Norway
    Scand J Clin Lab Invest 67:604-11. 2007
    ..To prospectively determine the effect of smoking cessation on markers of inflammation and endothelial cell activation...
  38. ncbi request reprint Under-reporting of dietary intake by smoking and non-smoking subjects counselled for hypercholesterolaemia
    S Tonstad
    Medical Department A, National Hospital, Oslo, Norway
    J Intern Med 245:337-44. 1999
    ..We asked whether under-reporting of energy and cigarette smoking were associated with choice of foods and dietary composition amongst subjects with hypercholesterolaemia who had received dietary instruction to lower serum cholesterol...
  39. doi request reprint Effects of a low glycemic load diet versus a low-fat diet in subjects with and without the metabolic syndrome
    T O Klemsdal
    Department of Preventive Cardiology, Center for Preventive Medicine, Ullevaal University Hospital, Oslo, Kirkeveien 166, N 0407 Oslo, Norway
    Nutr Metab Cardiovasc Dis 20:195-201. 2010
    ..The study aim was to compare a low glycemic load (LGL) diet versus a low-fat diet in a trial with a moderately intense dietary intervention in subjects with varying degrees of metabolic syndrome...
  40. doi request reprint The long-term influence of orlistat on dietary intake in obese subjects with components of metabolic syndrome
    M Svendsen
    Department of Preventive Cardiology, Ulleval University Hospital, Oslo, Norway
    J Hum Nutr Diet 22:55-63. 2009
    ..The present study examined the effect of orlistat on dietary intake, especially fat intake, during long-term weight maintenance...
  41. ncbi request reprint Dietary and antismoking advice and ischemic heart disease mortality in men with normal or high fasting triacylglycerol concentrations: a 23-y follow-up study
    Ingrid Ellingsen
    Department of Preventive Cardiology, Ullev degrees al University Hospital, Oslo, Norway
    Am J Clin Nutr 78:935-40. 2003
    ..The study showed a significant reduction in ischemic heart disease (IHD) events in the intervention group...
  42. ncbi request reprint Serum cholesterol response to replacing butter with a new trans-free margarine in hypercholesterolemic subjects
    S Tonstad
    Lipid Clinic, Medical Department A, National Hospital, Oslo, Norway
    Nutr Metab Cardiovasc Dis 11:320-6. 2001
    ..A food company has used data concerning the cholesterolemic effects of individual fatty acids, including trans fatty acids, to develop a commercially available and virtually trans-free margarine...
  43. ncbi request reprint Elevated Framingham risk score in HIV-positive patients on highly active antiretroviral therapy: results from a Norwegian study of 721 subjects
    B M Bergersen
    Department of Infectious Diseases, Ulleval University Hospital, 0407 Oslo, Norway
    Eur J Clin Microbiol Infect Dis 23:625-30. 2004
    ..In patients with elevated lipid levels, a change in the HAART regimen or treatment with lipid-lowering drugs should be considered...
  44. ncbi request reprint A rational approach to treating hypercholesterolaemia in children. Weighing the risks and benefits
    S Tonstad
    Ulleval Hospital, Oslo, Norway
    Drug Saf 16:330-41. 1997
    ..Drug treatment should be restricted to children who are at exceptionally high risk of disease, usually those with genetic dyslipidaemias...
  45. ncbi request reprint Bupropion SR for smoking cessation in smokers with cardiovascular disease: a multicentre, randomised study
    S Tonstad
    Department of Preventative Cardiology, Ulleval University Hospital, N 0407, Oslo, Norway
    Eur Heart J 24:946-55. 2003
    ..To investigate the safety and efficacy of bupropion sustained release (bupropion SR) in promoting abstinence from smoking in subjects with cardiovascular disease (CVD)...
  46. pmc Mothers' negative affectivity during pregnancy and food choices for their infants
    S E Hampson
    Oregon Research Institute, Eugene, OR, USA 2 Department of Nutrition, University of Oslo, Blindern, Oslo, Norway
    Int J Obes (Lond) 34:327-31. 2010
    ..The objective of this study was to analyze whether maternal negative affectivity assessed in pregnancy is related with subsequent infant food choices...
  47. ncbi request reprint Effectiveness of low-dose lovastatin combined with low-dose colestipol in moderate to severe primary hypercholesterolaemia
    S Tonstad
    Department of Medicine A, Rikshospitalet, Oslo, Norway
    Scand J Clin Lab Invest 53:457-63. 1993
    ..No change was seen in the placebo group. Thus, low-dose combination therapy with lovastatin and colestipol, in conjunction with dietary treatment, is effective in moderate to severe primary hypercholesterolaemia, and is well tolerated...
  48. ncbi request reprint Stratification of risk in children with familial hypercholesterolemia with focus on psychosocial issues
    S Tonstad
    Department of Preventive Cardiology, Preventive Medicine Center, Ulleval University Hospital, N 0407 Oslo, Norway
    Nutr Metab Cardiovasc Dis 11:64-7. 2001
    ..This paper discusses the clinical implications of making a diagnosis of familial hypercholesterolemia (FH) in children and data on psychosocial issues...
  49. doi request reprint Weight cycling and risk of forearm fractures: a 28-year follow-up of men in the Oslo Study
    Anne Johanne Søgaard
    Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway
    Am J Epidemiol 167:1005-13. 2008
    ..These findings suggest that weight cycling may predict forearm fracture in elderly men and indicate that the potentially harmful effects of weight cycling are related to the number of episodes occurring at ages 25-50 years...
  50. ncbi request reprint Does bupropion have advantages over other medical therapies in the cessation of smoking?
    Serena Tonstad
    Department of Preventice Cardiology, Ulleval University Hospital, Oslo, Norway
    Expert Opin Pharmacother 5:727-34. 2004
    ..Beyond randomised clinical trials, the effectiveness of bupropion has been shown in clinical practice and managed-care settings...
  51. doi request reprint Psychiatric adverse events in randomized, double-blind, placebo-controlled clinical trials of varenicline: a pooled analysis
    Serena Tonstad
    Department of Preventive Cardiology, Oslo University Hospital Ulleval, Oslo, Norway
    Drug Saf 33:289-301. 2010
    ..In postmarketing surveillance, neuropsychiatric symptoms have appeared; however, their incidence and causal relationship to varenicline is not known...
  52. ncbi request reprint Colestipol tablets in adolescents with familial hypercholesterolaemia
    S Tonstad
    Lipid Clinic, Medical Department A, Rikshospitalet, Oslo, Norway
    Acta Paediatr 85:1080-2. 1996
    ..All preferred the tablets to resin granules they had tried previously. We conclude that low-dose colestipol tablets appear to be safe and effective, and are preferred by adolescents...
  53. ncbi request reprint Does maternal or paternal heredity affect carotid atherosclerosis in children with familial hypercholesterolaemia?
    S Tonstad
    Lipid Clinic, Medical Department A, Rikshospitalet, Oslo, Norway
    Acta Paediatr 89:1490-2. 2000
    ..We found that carotid intima-media thickness and prevalence of plaque did not differ between children with familial hypercholesterolaemia who inherited FH maternally or paternally...
  54. ncbi request reprint Improved fibrinolysis after 1-year treatment with HMG CoA reductase inhibitors in patients with coronary heart disease
    Ingebjørg Seljeflot
    Center for Clinical Research, Ulleval University Hospital, Oslo, Norway
    Thromb Res 105:285-90. 2002
    ..The results indicate that the drugs promote a profibrinolytic profile, and may in part explain the benefit of statin treatment rendered in the prevention of CHD...
  55. doi request reprint Treatment with the PPARgamma agonist rosiglitazone downregulates interleukin-1 receptor antagonist in individuals with metabolic syndrome
    Bente Halvorsen
    Research Institute for Internal Medicine, Ulleval Hospital, Oslo University Hospital, Oslo, Norway
    Eur J Endocrinol 162:267-73. 2010
    ..The balance between protective and proatherogenic effects may differ in various patient populations. We studied the effect of rosiglitazone on inflammatory markers in patients with metabolic syndrome (MetSyn)...
  56. ncbi request reprint Predictiveness of body mass index for fatal coronary heart disease in men according to length of follow-up: a 21-year prospective cohort study
    Lise Lund Haheim
    Norwegian Health Service Research Centre, Department of Preventive Cardiology, Preventive Medicine Clinic, Ulleval University Hospital, Oslo, Norway
    Scand J Public Health 35:4-10. 2007
    ..To test the association between body mass index (BMI) and other coronary risk factors and the risk of a fatal coronary heart disease (CHD) event in different time periods during follow-up...
  57. ncbi request reprint [How to identify individuals with elevated cardiovascular risk?]
    Tor Ole Klemsdal
    Avdeling for preventiv kardiologi, Klinikk for forebyggende medisin, Medisinsk divisjon, Ulleval universitetssykehus, 0407 Oslo
    Tidsskr Nor Laegeforen 124:799-801. 2004
    ..In some individuals with intermediate risk, additionally non-invasive tests may be of value in order to ensure that sufficient information has been obtained for a recommendation of preventive measures...
  58. ncbi request reprint Trends in the incidence of acute myocardial infarction and stroke: a 21-year follow-up of the Oslo study
    Lise Lund Haheim
    Norwegian Health Services Research Centre, Oslo, Norway
    Scand Cardiovasc J 38:216-21. 2004
    ..To explore changes in the incidence of fatal and nonfatal myocardial infarction (MI) and stroke in the same male population over two decades...
  59. ncbi request reprint Does short-term smoking cessation reduce plasma total homocysteine concentrations?
    S Tonstad
    Department of Preventive Cardiology, Ulleval Hospital, Oslo, Norway
    Scand J Clin Lab Invest 62:279-84. 2002
    ..Likewise, no differences were found between quitters and non-quitters whose baseline homocysteine concentrations were above the 75th percentile...
  60. doi request reprint Effect of orlistat on eating behavior among participants in a 3-year weight maintenance trial
    Mette Svendsen
    Department of Preventive Cardiology, Ulleval University Hospital, Oslo, Norway
    Obesity (Silver Spring) 16:327-33. 2008
    ..To examine the effect of orlistat on dietary restraint, disinhibition, hunger, and binge eating and to understand the relation between changes in eating behavior and weight maintenance...
  61. doi request reprint [Risk factors and mortality--a follow-up of the Oslo Health Study from 1972-73]
    Ingar Holme
    Klinikk for forebyggende medisin, Senter for preventiv kardiologi, Oslo universitetssykehus, Ulleval, Norway
    Tidsskr Nor Laegeforen 131:456-60. 2011
    ..We have investigated the significance of a single measurement of risk factors for cardiovascular disease and total mortality for different time periods...
  62. ncbi request reprint [Is a healthy lifestyle worthwhile?]
    Ingar Holme
    Avdeling for epidemiologi og helseovervåking, Klinikk for forebyggende medisin, Ulleval universitetssykehus, 0407 Oslo
    Tidsskr Nor Laegeforen 126:2246-9. 2006
    ..We examined whether self-reported lifestyle habits were associated with biological markers, a range of symptoms and several illnesses in 2000...
  63. ncbi request reprint Use of sustained-release bupropion in specific patient populations for smoking cessation
    Serena Tonstad
    Department of Preventive Cardiology, Ulleval University Hospital, N 0407 Oslo, Norway
    Drugs 62:37-43. 2002
    ....
  64. ncbi request reprint Use of oral contraceptives and mortality during 14 years' follow-up of Norwegian women
    Sidsel Graff-Iversen
    Norwegian Institute of Public Health, Oslo, Norway
    Scand J Public Health 34:11-6. 2006
    ..The aim was to evaluate total and cardiovascular disease (CVD) mortality in relation to use of oral contraceptives (OC) in a cohort of women with a relatively high prevalence of smoking and high serum lipid levels...
  65. ncbi request reprint [Cardiovascular risk factors among 40-year old men and women in Oslo 1981-1999]
    Ingar Holme
    Avdeling for epidemiologi og helseovervåking, Klinikk for forebyggende medisin, Medisinsk divisjon, Ulleval universitetssykehus, 0407 Oslo
    Tidsskr Nor Laegeforen 124:3039-42. 2004
    ..Between 1981 and 1991, the City of Oslo offered all its 40-year-old citizens screening for risk factors for cardiovascular disease. We describe changes in risk factors over this period...
  66. doi request reprint Ethnic differences in metabolic syndrome among overweight and obese children and adolescents: the Oslo Adiposity Intervention Study
    Magnhild L Pollestad Kolsgaard
    Department of Pediatrics, Ullevaal University Hospital, Oslo, Norway
    Acta Paediatr 97:1557-63. 2008
    ..Are there differences in the prevalence of metabolic syndrome between obese and overweight Norwegian and immigrant children and adolescents?..
  67. doi request reprint Elevated visfatin levels in overweight and obese children and adolescents with metabolic syndrome
    Magnhild L Kolsgaard
    Department of Pediatrics, Oslo University Hospital, Ullevaal, Norway
    Scand J Clin Lab Invest 69:858-64. 2009
    ..Adipokines have been implicated in the pathogenesis of metabolic syndrome (MetS) and insulin resistance. We investigated the association between these conditions and serum levels of visfatin, adiponectin and leptin...
  68. ncbi request reprint Accuracy of food intake reporting in obese subjects with metabolic risk factors
    Mette Svendsen
    Department of Preventive Cardiology, Ulleval University Hospital, Oslo, Norway
    Br J Nutr 95:640-9. 2006
    ..67 (95 % CI 0.54, 0.83)). In obese subjects with metabolic risk factors, intake of sweets, desserts and snacks, bread and dietary restraint were determinants of reporting accuracy...
  69. doi request reprint Bilberry juice modulates plasma concentration of NF-kappaB related inflammatory markers in subjects at increased risk of CVD
    Anette Karlsen
    Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, PO Box 1046, Blindern, 0316 Oslo, Norway
    Eur J Nutr 49:345-55. 2010
    ..We investigated the effect of bilberry juice on serum and plasma biomarkers of inflammation and antioxidant status in subjects with elevated levels of at least one risk factor for cardiovascular disease (CVD)...
  70. doi request reprint Vitamin C consumption is associated with less progression in carotid intima media thickness in elderly men: A 3-year intervention study
    Ingrid Ellingsen
    Department of Preventive Cardiology, Ulleval University Hospital, Oslo, Norway
    Nutr Metab Cardiovasc Dis 19:8-14. 2009
    ..Plant foods may lower the risk of cardiovascular disease...
  71. ncbi request reprint The detection and management of dyslipidaemia in children and adolescents
    L Ose
    Department of Medicine A, Rikshospitalet, Oslo, Norway
    Acta Paediatr 84:1213-5. 1995
    ..Screening should be limited to children with suspected familial hypercholesterolaemia. Guidelines for individualized dietary and drug therapy are suggested...
  72. ncbi request reprint Hormone therapy and mortality during a 14-year follow-up of 14 324 Norwegian women
    S Graff-Iversen
    Norwegian Institute of Public Health, Oslo, Norway
    J Intern Med 256:437-45. 2004
    ..We evaluated mortality from cardiovascular disease (CVD), coronary heart disease (CHD) and all causes in relation to use of any hormone therapy (HT) and HT with oestradiol and norethisterone or levonorgestrel...
  73. pmc Effects of an antiatherogenic diet during pregnancy on markers of maternal and fetal endothelial activation and inflammation: the CARRDIP study
    J Khoury
    Department of Obstetrics and Gynaecology, Rikshospitalet Radiumhospitalet Medical Centre, Oslo, Norway
    BJOG 114:279-88. 2007
    ..To study the effect of an antiatherogenic diet on maternal and cord blood concentrations of systemic biomarkers of endothelial cell activation, haemostasis and inflammation...
  74. ncbi request reprint A comparison of the effects of 2 doses of soy protein or casein on serum lipids, serum lipoproteins, and plasma total homocysteine in hypercholesterolemic subjects
    Serena Tonstad
    Department of Preventive Cardiology, Ulleval Hospital, Oslo, Norway
    Am J Clin Nutr 76:78-84. 2002
    ..The dose response of soy protein has not been established; neither has its effect on plasma total homocysteine...
  75. ncbi request reprint [New trends in the treatment of obesity]
    Serena Tonstad
    Avdeling for preventiv kardiologi, Klinikk for forebyggende medisin, Ulleval universitetssykehus, 0407 Oslo
    Tidsskr Nor Laegeforen 124:391-2. 2004
  76. pmc Suggestive evidence of associations between liver X receptor β polymorphisms with type 2 diabetes mellitus and obesity in three cohort studies: HUNT2 (Norway), MONICA (France) and HELENA (Europe)
    Karianne Solaas
    Department of Endocrinology, Oslo University Hospital, Aker, Oslo, Norway
    BMC Med Genet 11:144. 2010
    ..We aimed to assess the associations between single nucleotide polymorphisms (SNPs) in LXRβ and risk of type 2 diabetes mellitus (T2DM), obesity and related traits in 3 separate cohort studies...
  77. doi request reprint Bilateral oophorectomy before 50 years of age is significantly associated with the metabolic syndrome and Framingham risk score: a controlled, population-based study (HUNT-2)
    Anne Dørum
    Department of Gynecologic Oncology, The Norwegian Radium Hospital, Rikshospitalet HF, University of Oslo, N 0310 Oslo, Norway
    Gynecol Oncol 109:377-83. 2008
    ..We compared the prevalence of the metabolic syndrome (MetS) and Framingham cardiovascular risk scores in women with BOE before 50 years of age to age-matched controls in a population-based study...
  78. ncbi request reprint Altered hemostatic balance and endothelial activation in pregnant women with familial hypercholesterolemia
    Agot L Amundsen
    Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
    Thromb Res 120:21-7. 2007
    ..However, whether hemostatic and endothelial activation markers are increased in pregnant FH women compared with non-FH pregnancies, is unknown...
  79. doi request reprint Mutations in the melanocortin 4 receptor (MC4R) gene in obese patients in Norway
    T Wangensteen
    Department of Medical Genetics, Ulleval University Hospital, Oslo, Norway
    Exp Clin Endocrinol Diabetes 117:266-73. 2009
    ..Mutations in the melanocortin 4 receptor ( MC4R) gene are the most frequent cause of monogenic forms of obesity, but the reported prevalences of mutations in obese individuals diverge, varying from 0.2 to 5.8%...
  80. ncbi request reprint Choices for treatment of hyperlipidaemia
    S Tonstad
    Department of Preventive Cardiology, Preventive Medicine Clinic, Ulleval University Hospital, N 0407 Oslo, Norway
    J Inherit Metab Dis 26:289-98. 2003
    ..We suggest that the child's sex, serum cholesterol level and family history of premature cardiovascular disease may be used to stratify risk. Children at exceptional high risk may be considered for pharmacological treatment...
  81. doi request reprint Leg fat mass as measured by dual X-ray absorptiometry (DXA) impacts insulin resistance differently in obese women versus men
    Gunnar Aasen
    Spesialistsenteret Pilestredet Park, Pilestredet Park, Oslo, Norway
    Scand J Clin Lab Invest 69:181-9. 2009
    ..To investigate the association between regional fat mass (FM) and insulin resistance and dyslipidaemia in obese women and men...
  82. ncbi request reprint Low prevalence of high-density lipoprotein cholesterol level < 1 mmol/L in non-nucleoside reverse transcriptase inhibitor recipients
    Bente M Bergersen
    Department of Infectious Diseases, Ulleval University Hospital, 0407 Oslo, Norway
    Int J STD AIDS 16:365-9. 2005
    ..40; 95% CI 1.47-7.86; P = 0.004) for low HDL-c level. Our study shows that NNRTI recipients have a more favourable HDL-c profile than PI recipients, even when possible confounding factors are taken into account...
  83. ncbi request reprint Risk-factor profile for the incidence of subarachnoid and intracerebral haemorrhage, cerebral infarction, and unspecified stroke during 21 years' follow-up in men
    Lise Lund Håheim
    Norwegian Knowledge Centre for the Health Services, Oslo, Norway
    Scand J Public Health 34:589-97. 2006
    ..To study the risk-factor profile for the incidence of non-fatal and fatal stroke among middle-aged men according to the stroke subtypes subarachnoid or intracerebral haemorrhage, cerebral infarction, and unspecified stroke...
  84. ncbi request reprint Cardiovascular risks associated with smoking: a review for clinicians
    Serena Tonstad
    Department of Preventive Cardiology, Ulleval University Hospital, Oslo, Norway
    Eur J Cardiovasc Prev Rehabil 13:507-14. 2006
    ..Both nicotine replacement and bupropion have been shown to be well tolerated in populations with cardiovascular disease...
  85. ncbi request reprint [Treatment with statins of the elderly]
    Ingar Holme
    Avdeling for epidemiologi og helseovervåkning, Klinikk for forebyggende medisin, Ulleval universitetssykehus, Oslo
    Tidsskr Nor Laegeforen 124:167-9. 2004
    ..While the absolute risk of cardiovascular disease in the elderly is very high, the benefits of treatment may be reduced by adverse events, polypharmacy and competing risks...
  86. ncbi request reprint Children and statins
    S Tonstad
    Department of Preventive Cardiology, Ulleval University Hospital, Oslo, Norway
    Acta Paediatr 92:1001-2. 2003
    ..The question that remains is how to improve dietary and disease information. Conclusion: Children with familial hypercholesterolaemia who are taking statins have no reduction in quality of life or increase in anxiety...
  87. ncbi request reprint Two founder mutations in the LDL receptor gene in Norwegian familial hypercholesterolemia subjects
    T P Leren
    Department of Medical Genetics, Ulleval University Hospital, Oslo, Norway
    Atherosclerosis 111:175-82. 1994
    ..The presence of two founder mutations together with previously published data on the prevalence of FH in Norway, indicate that FH may be a more common disease in Norway than previously thought...
  88. ncbi request reprint Role of lipid-lowering pharmacotherapy in children
    S Tonstad
    Department of Preventive Cardiology, Preventive Medicine Clinic, Ulleval Hospital, Oslo, Norway
    Paediatr Drugs 2:11-22. 2000
    ..Short term studies show that HMG-CoA reductase inhibitors reduce LDL-cholesterol levels similarly in children and in adults. Thus, the drugs may be used in low dosages to treat some adolescents with exceptional risk of disease...
  89. doi request reprint Validation of ActiReg to measure physical activity and energy expenditure against doubly labelled water in obese persons
    Bo Egil Hustvedt
    Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Box 1046 Blindern, N 0316 Oslo, Norway
    Br J Nutr 100:219-26. 2008
    ..Despite slight underestimation ActiReg may be used to measure TEE in obese subjects on two premises: RMR should be measured, and the increased EE during weight-bearing activities in obese subjects should be considered...
  90. ncbi request reprint Effect of a cholesterol-lowering diet on maternal, cord, and neonatal lipids, and pregnancy outcome: a randomized clinical trial
    Janette Khoury
    Department of Obstetrics and Gynecology, National University Hospital, Oslo, Norway
    Am J Obstet Gynecol 193:1292-301. 2005
    ..We assessed the effect of a cholesterol-lowering diet on maternal, cord, and neonatal plasma lipids and pregnancy outcome...
  91. ncbi request reprint Two novel point mutations in the EGF precursor homology domain of the LDL receptor gene causing familial hypercholesterolemia
    T P Leren
    Department of Medical Genetics, Ulleval University Hospital, Oslo, Norway
    Hum Genet 96:241-2. 1995
    ..One mutation (delta N466) was a 3-bp deletion in exon 10 that deletes Asn in codon 466. The other (intron 11 +1, G-->T) was a splice donor mutation at position +1 of intron 11...
  92. ncbi request reprint Marked changes in plasma lipids and lipoproteins during pregnancy in women with familial hypercholesterolemia
    Agot Lia Amundsen
    Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, P O Box 1046 Blindern, 0316 Oslo, Norway
    Atherosclerosis 189:451-7. 2006
    ..In conclusion, the relative increase in plasma lipids was similar in pregnant women with FH and in healthy women, but the absolute magnitude was considerably larger in pregnant FH women...
  93. ncbi request reprint Implementation of guidelines to screen relatives of patients with premature coronary heart disease in a hospital setting
    Serena Tonstad
    Department of Preventive Cardiology, Ulleval University Hospital, Oslo, Norway
    Am J Cardiol 90:1211-4. 2002
    ..These findings indicate that most patients with premature CHD were willing to contact relatives for screening. Screening yielded a substantial percentage of relatives with additional CHD risk factors...
  94. ncbi request reprint Treatment of children with familial hypercholesterolemia
    Serena Tonstad
    Department of Preventive Cardiology, Preventive Medicine Clinic, Ulleval University Hospital, Oslo, Norway
    Expert Rev Cardiovasc Ther 1:135-41. 2003
    ..Gender, family history and LDL-cholesterol level can be used to stratify risk of coronary heart disease. Children that carry very high risk may benefit from starting statins after puberty...
  95. ncbi request reprint [Treatment with statins: further data from the Heart Protection Study]
    Serena Tonstad
    Avdeling for preventiv kardiologi, Klinikk for forebyggende medisin Medisinsk divisjon Ullevål universitetssykehus 0407 Oslo
    Tidsskr Nor Laegeforen 122:2777-80. 2002
    ..In meta-analysis, reduction in events is associated with reduction in serum low-density lipoprotein (LDL) cholesterol levels, however, some studies have proposed a threshold level for the effect...
  96. ncbi request reprint [Bupropion as an aid for smoking cessation]
    Serena Tonstad
    Avdeling for preventiv kardiologi Klinikk for forebyggende medisin Ullevål universitetssykehus 0407 Oslo
    Tidsskr Nor Laegeforen 122:2612-5. 2002
    ..Quitting smoking is a primary lifestyle option for reducing the risk of a number of diseases. Effective therapies include counselling, nicotine replacement and bupropion, a dopamine and noradrenaline reuptake inhibitor...
  97. ncbi request reprint Improvement of postprandial lipid handling and glucose tolerance in a non-diabetic population by the dual PPARalpha/gamma agonist, tesaglitazar
    Bjorn Fagerberg
    Wallenberg Laboratory for Cardiovascular Research, Sahlgrenska University Hospital, 41345 Goteborg, Sweden
    Diab Vasc Dis Res 4:174-80. 2007
    ..To conclude, postprandial dyslipidaemia and hyperglycaemia, indicators of increased vascular risk, were significantly improved by tesaglitazar treatment in these non-diabetic, hypertriglyceridaemic, abdominally obese subjects...
  98. ncbi request reprint A comparative study with rosuvastatin in subjects with metabolic syndrome: results of the COMETS study
    Anton F H Stalenhoef
    Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Eur Heart J 26:2664-72. 2005
    ..The efficacy and safety of rosuvastatin, atorvastatin, and placebo were compared in patients with the metabolic syndrome...
  99. ncbi request reprint [Genetic causes of obesity]
    Teresia Wangensteen
    Avdeling for medisinsk genetikk, Ulleval universitetssykehus, og Institutt for medisinsk genetikk, Universitetet i Oslo
    Tidsskr Nor Laegeforen 125:3090-3. 2005
    ..Overweight and obesity represent an increasing health problem. Both genetic and environmental factors contribute to the development of obesity. This article summarises the genetic aspects of these conditions...
  100. doi request reprint The gap between guidelines and practice in the treatment of type 2 diabetes A nationwide survey in Norway
    Trond G Jenssen
    Rikshospitalet University Hospital, Sognsvannsveien 20, N 0027 Oslo, Norway
    Diabetes Res Clin Pract 80:314-20. 2008
    ..In a nationwide sample of patients with type 2 diabetes we assessed the prevalence of complications and compliance with current guidelines...
  101. ncbi request reprint Effect of orlistat on weight regain and cardiovascular risk factors following a very-low-energy diet in abdominally obese patients: a 3-year randomized, placebo-controlled study
    Bjørn Richelsen
    Department of Endocrinology and Metabolism, Aarhus University Hospital, Aarhus, Denmark
    Diabetes Care 30:27-32. 2007
    ....