Fang Liu

Summary

Affiliation: The Norwegian Radium Hospital
Country: Norway

Publications

  1. pmc Comparison of hybridization-based and sequencing-based gene expression technologies on biological replicates
    Fang Liu
    Department of Tumor Biology, Rikshopitalet Radiumhospitalet Medical Center, Montebello, Oslo, Norway
    BMC Genomics 8:153. 2007
  2. pmc The human genomic melting map
    Fang Liu
    Department of Tumor Biology, Institute for Cancer Research, Rikshospitalet Radiumhospitalet Medical Center, Oslo, Norway
    PLoS Comput Biol 3:e93. 2007
  3. pmc Validation of oligoarrays for quantitative exploration of the transcriptome
    Vigdis Nygaard
    Department of Tumor Biology, Institute for Cancer Research, Norwegian Radium Hospital, Montebello, Oslo, Norway
    BMC Genomics 9:258. 2008
  4. doi Performance comparison of multiple microarray platforms for gene expression profiling
    Fang Liu
    Department of Tumor Biology, Institute for Cancer Research, Norwegian Radium Hospital, Montebello, Oslo, Norway
    Methods Mol Biol 802:141-55. 2012
  5. ncbi Downregulation of tissue factor by RNA interference in human melanoma LOX-L cells reduces pulmonary metastasis in nude mice
    Xiaolin Wang
    Biotechnology Center of Oslo, University of Oslo, Oslo, Norway
    Int J Cancer 112:994-1002. 2004
  6. pmc Effects of mRNA amplification on gene expression ratios in cDNA experiments estimated by analysis of variance
    Vigdis Nygaard
    Department of Tumor Biology, Institute for Cancer Research, The Norwegian Radium Hospital, Montebello, 0310 Oslo, Norway
    BMC Genomics 4:11. 2003
  7. ncbi Speed-up of DNA melting algorithm with complete nearest neighbor properties
    Eivind Tøstesen
    Department of Tumor Biology, The Norwegian Radium Hospital, N 0310 Oslo, Norway
    Biopolymers 70:364-76. 2003
  8. ncbi FigSearch: a figure legend indexing and classification system
    Fang Liu
    Department of Tumor Biology, Institute for Cancer Research, The Norwegian Radium Hospital, Montebello, 0310 Oslo, Norway
    Bioinformatics 20:2880-2. 2004
  9. ncbi Multi-group cancer outlier differential gene expression detection
    Fang Liu
    Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA
    Comput Biol Chem 31:65-71. 2007
  10. ncbi Synthesis, DNA-binding, cleavage, and cytotoxic activity of new 1,7-dioxa-4,10-diazacyclododecane artificial receptors containing bisguanidinoethyl or diaminoethyl double side arms
    Xin Sheng
    Department of Chemistry, State Key Laboratory of Coordination, Chemistry, Nanjing University, Nanjing, PR China
    Chemistry 13:9703-12. 2007

Collaborators

Detail Information

Publications60

  1. pmc Comparison of hybridization-based and sequencing-based gene expression technologies on biological replicates
    Fang Liu
    Department of Tumor Biology, Rikshopitalet Radiumhospitalet Medical Center, Montebello, Oslo, Norway
    BMC Genomics 8:153. 2007
    ..As part of an ongoing large-scale cross-platform data comparison framework, we report here a comparison based on identical samples between one-dye DNA microarray platforms and MPSS (Massively Parallel Signature Sequencing)...
  2. pmc The human genomic melting map
    Fang Liu
    Department of Tumor Biology, Institute for Cancer Research, Rikshospitalet Radiumhospitalet Medical Center, Oslo, Norway
    PLoS Comput Biol 3:e93. 2007
    ..The human DNA melting map may be further explored at http://meltmap.uio.no...
  3. pmc Validation of oligoarrays for quantitative exploration of the transcriptome
    Vigdis Nygaard
    Department of Tumor Biology, Institute for Cancer Research, Norwegian Radium Hospital, Montebello, Oslo, Norway
    BMC Genomics 9:258. 2008
    ..105. Our aim was to investigate whether the less resource demanding and more widespread oligoarray technique could provide data that were correlated to and had the same absolute scale as those obtained with MPSS and SAGE...
  4. doi Performance comparison of multiple microarray platforms for gene expression profiling
    Fang Liu
    Department of Tumor Biology, Institute for Cancer Research, Norwegian Radium Hospital, Montebello, Oslo, Norway
    Methods Mol Biol 802:141-55. 2012
    ..After stringent preprocessing, commercial arrays were more consistent than "in-house" arrays, and by most measures, one-dye platforms were more consistent than two-dye platforms...
  5. ncbi Downregulation of tissue factor by RNA interference in human melanoma LOX-L cells reduces pulmonary metastasis in nude mice
    Xiaolin Wang
    Biotechnology Center of Oslo, University of Oslo, Oslo, Norway
    Int J Cancer 112:994-1002. 2004
    ..The results provide a basis for investigating molecular mechanisms underlying the effects of TF on the metastatic capacity of LOX-L melanoma cells...
  6. pmc Effects of mRNA amplification on gene expression ratios in cDNA experiments estimated by analysis of variance
    Vigdis Nygaard
    Department of Tumor Biology, Institute for Cancer Research, The Norwegian Radium Hospital, Montebello, 0310 Oslo, Norway
    BMC Genomics 4:11. 2003
    ..We present a quantitative study of the variation and noise present in our data set obtained from experiments with either amplified or non-amplified material...
  7. ncbi Speed-up of DNA melting algorithm with complete nearest neighbor properties
    Eivind Tøstesen
    Department of Tumor Biology, The Norwegian Radium Hospital, N 0310 Oslo, Norway
    Biopolymers 70:364-76. 2003
    ..This can provide a better understanding of the physics of denaturation and the biology of genomes...
  8. ncbi FigSearch: a figure legend indexing and classification system
    Fang Liu
    Department of Tumor Biology, Institute for Cancer Research, The Norwegian Radium Hospital, Montebello, 0310 Oslo, Norway
    Bioinformatics 20:2880-2. 2004
    ..AVAILABILITY: A searchable Web interface, FigSearch, is accessible via http://pubgeneserver.uio.no/figsearch/ for all figures from the available corpus...
  9. ncbi Multi-group cancer outlier differential gene expression detection
    Fang Liu
    Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA
    Comput Biol Chem 31:65-71. 2007
    ..Supplementary information can be found at http://www.biostat.umn.edu/~baolin/research/orf.html...
  10. ncbi Synthesis, DNA-binding, cleavage, and cytotoxic activity of new 1,7-dioxa-4,10-diazacyclododecane artificial receptors containing bisguanidinoethyl or diaminoethyl double side arms
    Xin Sheng
    Department of Chemistry, State Key Laboratory of Coordination, Chemistry, Nanjing University, Nanjing, PR China
    Chemistry 13:9703-12. 2007
    ..In-vitro cytotoxic activities toward murine melanoma B16 cells and human leukemia HL-60 cells were also examined: Cu(2+)-4 shows the highest activity with IC(50) values of 1.62x10(-4) and 1.19x10(-5) M, respectively...
  11. ncbi Molecular epidemiology of rabies in Guangxi Province, south of China
    Qi Liu
    College of Animal Science and Technology, Guangxi University, 100 Daxue Road, Nanning 530004, Guangxi, China
    J Clin Virol 39:295-303. 2007
    ..Surveillance data for rabies in Guangxi Province in China showed that human rabies cases have gradually increased since 1996...
  12. ncbi Identification of cotton microRNAs and their targets
    Baohong Zhang
    Henan Institute of Science and Technology, Xinxiang, Henna, PR China
    Gene 397:26-37. 2007
    ....
  13. ncbi Clinical and molecular genetic analysis of a family with sitosterolemia and co-existing erythrocyte and platelet abnormalities
    Yanhua Su
    Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, 188 Shizi Street, Suzhou 215006, China
    Haematologica 91:1392-5. 2006
    ..Our results suggest that blood cells could be a target for the toxic effect of plasma phytosterols; the coexisting hematologic abnormalities might represent a specific subtype of sitosterolemia...
  14. ncbi Modulation of D2R-NR2B interactions in response to cocaine
    Xian Yu Liu
    Department of Basic Medical Science, University of Missouri Kansas City, School of Medicine, Kansas City, Missouri 64108, USA
    Neuron 52:897-909. 2006
    ..This type of dopamine-glutamate integration at the receptor level may be responsible for synergistically inhibiting the D2R-mediated circuits in the basal ganglia and fulfilling the stimulative effect of psychostimulants...
  15. pmc A UMLS-based spell checker for natural language processing in vaccine safety
    Herman D Tolentino
    Bacterial Vaccine Preventable Diseases Branch, Epidemiology and Surveillance Division, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    BMC Med Inform Decis Mak 7:3. 2007
    ..Our objective in this paper was to create a UMLS-based spelling error correction tool as a first step in the natural language processing (NLP) pipeline for AEFI reports...
  16. ncbi [Effects of triptolide and TNF-alpha on the expression of VEGF in Raji cells and on angiogenesis in ECV304 cells]
    Guo hui Cui
    Department of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 14:1008-12. 2006
    ..It is concluded that the expressions of VEGF in Raji cells are increased by TNF-alpha and suppressed by triptolide. VEGF and TNF-alpha induce angiogenesis and triptolide inhibits angiogenesis in ECV304 cells...
  17. ncbi Synthesis and DNA cleavage activity of artificial receptor 1,4,7-triazacyclononane containing guanidinoethyl and hydroxyethyl side arms
    Xin Sheng
    Department of Chemistry, State Key Laboratory of Coordination Chemistry, Nanjing University, Nanjing 210093, P R China
    J Org Chem 72:1799-802. 2007
    ..160 h-1 giving 107-fold rate acceleration over uncatalyzed DNA. The acceleration is driven by the spatial proximity of the nucleophilic hydroxyl group and the electrophilic activation for the phosphodiester by the guanidinium group...
  18. pmc Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis
    Xiao Mei Wang
    Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Exp Med 203:2895-906. 2006
    ..This study indicates a pivotal role for cav-1 in ECM regulation and suggests a novel therapeutic target for patients with pulmonary fibrosis...
  19. ncbi Expression profiling reveals dysregulation of cellular cytoskeletal genes in HBx-induced hepatocarcinogenesis
    Qiang Sun
    Genetic Laboratory of Development and Diseases, Institute of Biotechnology, Beijing, PR, China
    Cancer Biol Ther 6:668-74. 2007
    ..These findings propose for the first time that systemic dysregulation of cellular cytoskeletal genes is involved in HBx-induced hepatocarcinogenesis...
  20. ncbi Molecular genetic evidence of an independent origin of serous low malignant potential implants and lymph node inclusions
    Robert E Emerson
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Int J Gynecol Pathol 26:387-94. 2007
    ..However, in at least some cases, the implants and inclusions seem to arise independently from the associated ovarian serous LMP tumors...
  21. doi Quantitative proteomic signature of liver cancer cells: tissue transglutaminase 2 could be a novel protein candidate of human hepatocellular carcinoma
    Yulin Sun
    State Key Laboratory of Molecular Oncology, Department of Abdominal Surgery, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021 P R China
    J Proteome Res 7:3847-59. 2008
    ..These novel findings may provide important clues to identify new biomarkers of HCC and indirectly improve early detection of the disease...
  22. doi Exponential stability analysis for neural networks with time-varying delay
    Min Wu
    IEEE Trans Syst Man Cybern B Cybern 38:1152-6. 2008
    ..Two numerical examples are given to demonstrate its effectiveness...
  23. ncbi Cancer gene therapy of adenovirus-mediated anti-4-1BB scFv in immunocompetent mice
    Fang Liu
    Department of Pharmacology, Institute of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China
    Cancer Biol Ther 7:448-53. 2008
    ..These results indicated that nonreplicative adenovirus carrying the anti-4-1BB scFv gene possessed powerful in vivo anti-tumor efficacy and might be a valuable tool for cancer immunotherapy...
  24. doi Input reconstruction of chaos sensors
    Dongchuan Yu
    College of Automation Engineering, Qingdao University, Qingdao, Shandong 266071, People s Republic of China
    Chaos 18:023106. 2008
    ..We discuss also how to improve the robustness of reconstruction. Some examples are presented to illustrate the measurement signal reconstruction method suggested...
  25. pmc The ubiquitin-proteasome pathway mediates gelsolin protein downregulation in pancreatic cancer
    Xiao Guang Ni
    Department of Endoscopy, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Mol Med 14:582-9. 2008
    ..In conclusion, gelsolin levels are actively downregulated in pancreatic cancer and enhanced targeting of gelsolin to the ubiquitin-proteasome pathway is an important contributing factor for this effect...
  26. ncbi Identification of candidate biomarkers for hepatocellular carcinoma through pre-cancerous expression analysis in an HBx transgenic mouse
    Qiang Sun
    Genetic Laboratory of Development and Diseases, Institute of Biotechnology, Beijing, PR China
    Cancer Biol Ther 6:1532-8. 2007
    ..This work describes a new way to identify novel biomarker candidates for HCC diagnosis...
  27. doi DNA binding, cleavage, and cytotoxic activity of the preorganized dinuclear zinc(II) complex of triazacyclononane derivatives
    Xin Sheng
    Department of Chemistry, State Key Laboratory of Coordination Chemistry, Nanjing University, Nanjing 210093, People s Republic of China
    Bioconjug Chem 19:490-8. 2008
    ..A hydrolytic mechanism of the cleavage process was suggested, and a preliminary study of the antitumor activity was also conducted...
  28. ncbi Intratumor injection of oncolytic adenovirus expressing HSP70 prolonged survival in melanoma B16 bearing mice by enhanced immune response
    Zhen Ren
    Department of Pharmacology, College of Basic Medical Sciences, Shanghai Jiao Tong University, Shanghai, PR China
    Cancer Biol Ther 7:191-95. 2008
    ..These results indicated that the recombinant oncolytic adenovirus over-expressing HSPs possessed powerful in vivo anti-tumor efficacy and might be a valuable approach for cancer immune gene therapy...
  29. pmc Overexpression of angiotensinogen increases tubular apoptosis in diabetes
    Fang Liu
    Université de Montréal Centre hospitalier de l Université de Montréal Hôtel Dieu, Research Centre Pavillon Masson, 3850 Saint Urbain Street, Montreal, Quebec, Canada H2W 1T8
    J Am Soc Nephrol 19:269-80. 2008
    ..In conclusion, intrarenal RAS activation and high glucose may act in concert to increase tubular apoptosis in diabetes, independent of systemic hypertension...
  30. ncbi Attenuation of interstitial fibrosis and tubular apoptosis in db/db transgenic mice overexpressing catalase in renal proximal tubular cells
    Marie Luise Brezniceanu
    Universite de Montreal, Centre hospitalier de l Université de Montréal CHUM Hôtel Dieu, Research Centre, Pavillon Masson, 3850 Saint Urbain St, Montreal, Quebec, Canada
    Diabetes 57:451-9. 2008
    ....
  31. ncbi PICO Linguist and BabelMeSH: development and partial evaluation of evidence-based multilanguage search tools for MEDLINE/PubMed
    Paul Fontelo
    High Performance Computing and Communications, Lister Hill National Center for Biomedical Communications, NIH, Bethesda, MD 20894, USA
    Stud Health Technol Inform 129:817-21. 2007
    ..PICO Linguist and BabelMeSH could be useful and convenient tools in finding current evidence sources in the medical literature especially for non-English medical terms that may be difficult to express in English...
  32. ncbi Effect of protein kinase C on T lymphocyte proliferation and apoptosis in acute idiopathic thrombocytopenic purpura
    Fang Liu
    Department of Microbiology and Immunology, Guangdong Medical College, Zhanjiang, Guangdong Province, China
    Acta Haematol 116:173-80. 2006
    ..PKC activation may enhance T lymphocyte activity, suppress T cell apoptosis, and be involved in thrombocyte damage, which can be related to the immunity pathogenesis of ITP...
  33. ncbi Correlations between growth parameters of spoilage micro-organisms and shelf-life of pork stored under air and modified atmosphere at -2, 4 and 10 degrees C
    Fang Liu
    Department of Food Science and Technology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai Qi Xin Road 2678, Shanghai 201101, China
    Food Microbiol 23:578-83. 2006
    ..The mu(max) and lambda of micro-organisms correlated well with microbial and sensory shelf-life. The shelf-life of pork is mainly correlated with the growth parameters of mu(max) and lambda than by N(max)...
  34. ncbi [Experimental study on anticancer effect of curcumin on Raji cells in vitro]
    Chun Yan Sun
    Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022
    Zhongguo Zhong Xi Yi Jie He Za Zhi 24:1003-6. 2004
    ..To study the anticancer effect and mechanism of curcumin on Raji cells in vitro and compared the cytotoxicities of curcumin on Raji cells and normal human peripheral blood mononuclear cell (PBMC)...
  35. pmc The Smad3 linker region contains a transcriptional activation domain
    Guannan Wang
    Center for Advanced Biotechnology and Medicine, Rutgers, The State University of New Jersey, 679 Hoes Lane, Piscataway, NJ 08854, USA
    Biochem J 386:29-34. 2005
    ..Thus our findings uncover an important function of the Smad3 linker region in Smad-mediated transcriptional control...
  36. ncbi Effects of fluoride on lipid peroxidation, DNA damage and apoptosis in human embryo hepatocytes
    Ai Guo Wang
    Department of Environmental Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China
    Biomed Environ Sci 17:217-22. 2004
    ..To investigate the effects of fluoride on lipid peroxidation, DNA damage and apoptosis in human embryo hepatocyte L-02 cells...
  37. ncbi Gene expression changes induced by green tea polyphenol (-)-epigallocatechin-3-gallate in human bronchial epithelial 21BES cells analyzed by DNA microarray
    Ragini Vittal
    Susan Lehman Cullman Laboratory for Cancer Research, Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers University, State University of New Jersey, 164 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Mol Cancer Ther 3:1091-9. 2004
    ..The elucidation of gene expression changes between H2O2-dependent and H2O2-independent responses helps us better understand the cancer chemopreventive and anticancer actions of EGCG...
  38. ncbi TRIM45, a novel human RBCC/TRIM protein, inhibits transcriptional activities of ElK-1 and AP-1
    Yuequn Wang
    The Center for Heart Development, College of Life Sciences, Hunan Normal University, Changsha 410081, Hunan, People s Republic of China
    Biochem Biophys Res Commun 323:9-16. 2004
    ..Overexpression of TRIM45 in COS-7 cells inhibits the transcriptional activities of ElK-1 and AP-1. These results suggest that TRIM45 may act as a new transcriptional repressor in mitogen-activated protein kinase signaling pathway...
  39. ncbi Inhibiting apoptosis of CTLL-2 cells to enhance their GVL effects via anti-Fas ribozyme
    Min Zhang
    Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
    Acta Biochim Biophys Sin (Shanghai) 36:559-65. 2004
    ..The results demonstrated anti-Fas ribozyme could efficiently cleave Fas and inhibit Fas-mediated apoptosis of CTLL-2 cells to improve their viability. Our study made a basis for enhancing CTLL-2 cells anti-leukemia effect in DLI...
  40. ncbi Using genetic algorithm to identify completely unknown system in FTIR spectra analysis
    Fang Liu
    Laboratory of Advanced Spectroscopy, Nanjing University of Science and Technology, Jiangsu, Nanjing, PR China
    J Environ Sci Health A Tox Hazard Subst Environ Eng 39:1525-33. 2004
    ..The maximal relative error is no more than 10%. It means that GA has the capability of simultaneous identification and prediction, especially for those completely unknown mixed spectra in FTIR...
  41. pmc Carbon monoxide protects against liver failure through nitric oxide-induced heme oxygenase 1
    Brian S Zuckerbraun
    Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    J Exp Med 198:1707-16. 2003
    ....
  42. pmc MKK3 mitogen-activated protein kinase pathway mediates carbon monoxide-induced protection against oxidant-induced lung injury
    Leo E Otterbein
    Section of Pulmonary and Critical Care Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
    Am J Pathol 163:2555-63. 2003
    ....
  43. ncbi Synthesis of beta-substituted cationic porphyrins and their interactions with DNA
    Bo Chen
    College of Chemistry and Molecular Sciences, Wuhan University, Hubei Wuhan 430072, P R China
    Bioorg Med Chem Lett 13:3731-3. 2003
    ..We found that substituents at the beta-position of porphyrins (7 and 8) have apparently affected their interactions with DNA compared with non-beta-substituted porphyrins (10)...
  44. pmc Repression of Smad transcriptional activity by PIASy, an inhibitor of activated STAT
    Jianyin Long
    Center for Advanced Biotechnology and Medicine, Susan Lehman Cullman Laboratory for Cancer Research, Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, State University of New Jersey, 679 Hoes Lane, Piscataway, NJ 08854, USA
    Proc Natl Acad Sci U S A 100:9791-6. 2003
    ..Taken together, our studies indicate that PIASy can inhibit TGF-beta/Smad transcriptional responses through interactions with Smad proteins and HDAC...
  45. ncbi Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury
    Leo E Otterbein
    Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Montefiore University Hospital, Pittsburgh, Pennsylvania, USA
    Nat Med 9:183-90. 2003
    ..These findings demonstrate a protective role for CO in vascular injury and support its use as a therapeutic agent...
  46. pmc NMR structure of HI0004, a putative essential gene product from Haemophilus influenzae, and comparison with the X-ray structure of an Aquifex aeolicus homolog
    Deok Cheon Yeh
    Center for Advanced Research in Bio technology, University of Maryland Biotechnology Institute, 9600 Gudel sky Drive, Rockville, MD 20850, USA
    Protein Sci 14:424-30. 2005
    ..Despite this level of sequence homology, significant differences exist between the two structures. These differences are described along with possible functional implications of the structures...
  47. ncbi Folding efficiency is rate-limiting in dopamine D4 receptor biogenesis
    Kathleen Van Craenenbroeck
    Laboratory of Molecular Neurobiology, Center for Addiction and Mental Health, Toronto, Ontario M5T 1R8, Canada
    J Biol Chem 280:19350-7. 2005
    ..Consequently, the clinical profile of dopaminergic ligands, including antipsychotics, may include their ability to serve as pharmacological chaperones...
  48. ncbi A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies
    Winston Patrick Kuo
    Department of Developmental Biology, Harvard School of Dental Medicine, 188 Longwood Ave, Boston, Massachusetts 02115, USA
    Nat Biotechnol 24:832-40. 2006
    ..We demonstrate that, after stringent preprocessing, commercial arrays were more consistent than in-house arrays, and by most measures, one-dye platforms were more consistent than two-dye platforms...
  49. ncbi [Preparation of placental-eluted gamma globulin and its immunosuppressive effect in vitro and in vivo]
    Fang Liu
    Peking University Institute of Hematology, Peking University People Hospital, Beijing 100044, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 14:529-34. 2006
    ..In short, PEGG may be a potent therapeutic agent for GVHD...
  50. pmc Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models
    Antony A Cooper
    School of Biological Sciences, University of Missouri Kansas City, Kansas City, MO 64110, USA
    Science 313:324-8. 2006
    ..Thus, synucleinopathies may result from disruptions in basic cellular functions that interface with the unique biology of particular neurons to make them especially vulnerable...
  51. ncbi Parallel encoding of focus and interrogative meaning in Mandarin intonation
    Fang Liu
    Department of Linguistics, University of Chicago, IL 60637, USA
    Phonetica 62:70-87. 2005
    ....
  52. ncbi [Hydroxyapatite nanoparticles: a novel material of gene carrier]
    Shaihong Zhu
    General Surgical Department, The Third Xiangya Hospital, Central South University, Changsha 410013, China
    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 22:980-4. 2005
    ..This study demonstrates that Hydroxyapatite nanoparticles could be used as gene carriers...
  53. ncbi [Expression of BLM mRNA in six tumor cell strains]
    Xue Yi
    Department of Hematology, Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430022, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 13:823-6. 2005
    ..01), but no cDNA sequence abnormality of BLM gene in these tumors cells was observed. It is concluded that the increase of expressing level of BLM mRNA may play an important role in the development of these tumors...
  54. ncbi Anticancer effect of curcumin on human B cell non-Hodgkin's lymphoma
    Chunyan Sun
    Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
    J Huazhong Univ Sci Technolog Med Sci 25:404-7. 2005
    ..Morever, curcumin has low toxicity on NPBMNCs but can selectively induce apoptosis in Raji cells...
  55. pmc Identification of Pseudomonas aeruginosa-induced genes in human mast cells using suppression subtractive hybridization: up-regulation of IL-8 and CCL4 production
    Genlou Sun
    Biology Department, Saint Mary s University, Halifax, Nova Scotia, Canada
    Clin Exp Immunol 142:199-205. 2005
    ..aeruginosa pathogenesis. Thus, SSH is an effective approach by identifying potential molecular targets for the study of mechanisms involved in P. aeruginosa and mast cell interaction...
  56. ncbi Suprarenal aortic clamping and reperfusion decreases medullary and cortical blood flow by decreased endogenous renal nitric oxide and PGE2 synthesis
    Stuart I Myers
    McGuire Research Institute McGuire VA Medical Center and Department of Surgery, Virginia Commonwealth University, 23298, USA
    J Vasc Surg 42:524-31. 2005
    ....
  57. ncbi Pharmacological characterization of guinea pig chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)
    Fang Liu
    Department of Inflammation, Millennium Pharmaceutical Inc, Cambridge, MA 02139, USA
    Prostaglandins Other Lipid Mediat 76:133-47. 2005
    ..These results indicate that PGD(2) and the stable metabolite, Delta(12)-PGJ(2), play important roles in CRTH2 activation in the guinea pig...
  58. ncbi Carbon monoxide prevents multiple organ injury in a model of hemorrhagic shock and resuscitation
    Brian S Zuckerbraun
    Department of Surgery, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Shock 23:527-32. 2005
    ..The precise cellular mechanisms involved require further elucidation. CO may prove to be an adjunctive therapy that could be instituted rapidly and with ease as an out-of-hospital therapeutic modality for severe blood loss after trauma...
  59. pmc HU-alpha binds to the putative double-stranded DNA mimic HI1450 from Haemophilus influenzae
    Lisa M Parsons
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, 9600 Gudelsky Drive, Rockville, MD 20850, USA
    Protein Sci 14:1684-7. 2005
    ..These results show that HI1450 and its structural homolog, Ugi, use similar parts of their structures to recognize DNA-binding proteins...
  60. ncbi RRR-alpha-tocopheryl succinate inhibits human gastric cancer SGC-7901 cell growth by inducing apoptosis and DNA synthesis arrest
    Kun Wu
    Department of Nutrition and Food Hygiene, Public Health School, Harbin Medical University, Harbin 150001, Heilongjiang Province, China
    World J Gastroenterol 8:26-30. 2002
    ..To investigate the effects of growth inhibition of human gastric cancer SGC-7901 cell with RRR-alpha-tocopheryl succinate (VES), a derivative of natural Vitamin E, via inducing apoptosis and DNA synthesis arrest...