Arne Reimers

Summary

Affiliation: St. Olavs Hospital
Country: Norway

Publications

  1. ncbi request reprint [Oral contraceptives can affect the metabolism of other drugs]
    Arne Reimers
    Avdeling for klinisk farmakologi, St Olavs Hospital, 7006 Trondheim
    Tidsskr Nor Laegeforen 124:1785-7. 2004
  2. ncbi request reprint Lamotrigine serum concentrations throughout the menstrual cycle--a study of 2 cases
    Arne Reimers
    Department of Clinical Pharmacology, St Olavs University Hospital, Trondheim, Norway
    Clin Neuropharmacol 29:160-2. 2006
  3. doi request reprint Serum concentration/dose ratio of levetiracetam before, during and after pregnancy
    Andreas Austgulen Westin
    Department of Clinical Pharmacology, St Olavs Hospital, Olav Kyrres gate 17, N 7006 Trondheim, Norway
    Seizure 17:192-8. 2008
  4. ncbi request reprint Drug interactions between lamotrigine and psychoactive drugs: evidence from a therapeutic drug monitoring service
    Arne Reimers
    Department of Clinical Pharmacology, St Olavs University Hospital, 7006 Trondheim, Norway
    J Clin Psychopharmacol 25:342-8. 2005
  5. ncbi request reprint Acute lamotrigine overdose in an adolescent
    Arne Reimers
    Department of Clinical Pharmacology, St Olavs University Hospital, Trondheim, Norway
    Ther Drug Monit 29:669-70. 2007
  6. ncbi request reprint Lamotrigine in children and adolescents: the impact of age on its serum concentrations and on the extent of drug interactions
    Arne Reimers
    Department of Clinical Pharmacology, St Olavs University Hospital, 7006 Trondheim, Norway
    Eur J Clin Pharmacol 63:687-92. 2007
  7. pmc Expression of UDP-glucuronosyltransferase 1A4 in human placenta at term
    Arne Reimers
    Department of Clinical Pharmacology, St Olavs University Hospital, and Department of Neuroscience, Faculty of Medicine, NTNU, P O Box 3250 Sluppen, 7006, Trondheim, Norway
    Eur J Drug Metab Pharmacokinet 35:79-82. 2011
  8. ncbi request reprint Ethinyl estradiol, not progestogens, reduces lamotrigine serum concentrations
    Arne Reimers
    Department of Clinical Pharmacology, St Olavs Hospital, and Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway
    Epilepsia 46:1414-7. 2005
  9. doi request reprint Trends and changes in the clinical use of lamotrigine
    Arne Reimers
    Department of Clinical Pharmacology, St Olavs University Hospital, Trondheim, Norway
    Pharmacoepidemiol Drug Saf 18:132-9. 2009
  10. doi request reprint Serum concentration/dose ratio of topiramate during pregnancy
    Andreas Austgulen Westin
    Department of Clinical Pharmacology, St Olavs University Hospital, Trondheim, Norway
    Epilepsia 50:480-5. 2009

Collaborators

Detail Information

Publications20

  1. ncbi request reprint [Oral contraceptives can affect the metabolism of other drugs]
    Arne Reimers
    Avdeling for klinisk farmakologi, St Olavs Hospital, 7006 Trondheim
    Tidsskr Nor Laegeforen 124:1785-7. 2004
  2. ncbi request reprint Lamotrigine serum concentrations throughout the menstrual cycle--a study of 2 cases
    Arne Reimers
    Department of Clinical Pharmacology, St Olavs University Hospital, Trondheim, Norway
    Clin Neuropharmacol 29:160-2. 2006
    ..To measure the serum concentrations of lamotrigine throughout a complete menstrual cycle...
  3. doi request reprint Serum concentration/dose ratio of levetiracetam before, during and after pregnancy
    Andreas Austgulen Westin
    Department of Clinical Pharmacology, St Olavs Hospital, Olav Kyrres gate 17, N 7006 Trondheim, Norway
    Seizure 17:192-8. 2008
    ..To investigate changes in levetiracetam (LEV) serum concentration/dose ratio (C/D-ratio) in relation to pregnancy...
  4. ncbi request reprint Drug interactions between lamotrigine and psychoactive drugs: evidence from a therapeutic drug monitoring service
    Arne Reimers
    Department of Clinical Pharmacology, St Olavs University Hospital, 7006 Trondheim, Norway
    J Clin Psychopharmacol 25:342-8. 2005
    ..Concerning pharmacokinetic drug interactions, we conclude that lamotrigine can be safely combined with most psychotropic drugs...
  5. ncbi request reprint Acute lamotrigine overdose in an adolescent
    Arne Reimers
    Department of Clinical Pharmacology, St Olavs University Hospital, Trondheim, Norway
    Ther Drug Monit 29:669-70. 2007
  6. ncbi request reprint Lamotrigine in children and adolescents: the impact of age on its serum concentrations and on the extent of drug interactions
    Arne Reimers
    Department of Clinical Pharmacology, St Olavs University Hospital, 7006 Trondheim, Norway
    Eur J Clin Pharmacol 63:687-92. 2007
    ..To investigate the impact of age and co-treatment with other drugs on the serum concentrations of lamotrigine in children and adolescents...
  7. pmc Expression of UDP-glucuronosyltransferase 1A4 in human placenta at term
    Arne Reimers
    Department of Clinical Pharmacology, St Olavs University Hospital, and Department of Neuroscience, Faculty of Medicine, NTNU, P O Box 3250 Sluppen, 7006, Trondheim, Norway
    Eur J Drug Metab Pharmacokinet 35:79-82. 2011
    ..Since LTG is primarily metabolized by UGT1A4 and this isozyme is shown to be present in placenta at term, it may be hypothesized that the placenta is involved in the fall of LTG serum concentrations during pregnancy...
  8. ncbi request reprint Ethinyl estradiol, not progestogens, reduces lamotrigine serum concentrations
    Arne Reimers
    Department of Clinical Pharmacology, St Olavs Hospital, and Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway
    Epilepsia 46:1414-7. 2005
    ..To study the interaction between lamotrigine (LTG) and hormonal contraception...
  9. doi request reprint Trends and changes in the clinical use of lamotrigine
    Arne Reimers
    Department of Clinical Pharmacology, St Olavs University Hospital, Trondheim, Norway
    Pharmacoepidemiol Drug Saf 18:132-9. 2009
    ..To investigate long-term trends and changes in the pattern of use of lamotrigine (LTG)...
  10. doi request reprint Serum concentration/dose ratio of topiramate during pregnancy
    Andreas Austgulen Westin
    Department of Clinical Pharmacology, St Olavs University Hospital, Trondheim, Norway
    Epilepsia 50:480-5. 2009
    ..To study the impact of pregnancy on the serum concentration/dose ratio (C/D-ratio) of topiramate (TPM)...
  11. doi request reprint Second-generation antiepileptic drugs and pregnancy: a guide for clinicians
    Arne Reimers
    Department of Clinical Pharmacology, St Olavs University Hospital, 7006 Trondheim, Norway
    Expert Rev Neurother 12:707-17. 2012
    ..The authors review the recommendations and clinical research on modern AED treatment during pregnancy, highlighting current experience with second-generation drugs...
  12. ncbi request reprint [Toxicological screening of medicines and drugs of abuse in emergency cases]
    Arne Helland
    Avdeling for klinisk farmakologi, St Olavs Hospital, 7006 Trondheim
    Tidsskr Nor Laegeforen 128:42-5. 2008
    ..In some situations, and particularly when intoxications are suspected, it would be advantageous if medicines and drugs of abuse could be swiftly detected in serum or urine...
  13. doi request reprint Lamotrigine and its N2-glucuronide during pregnancy: the significance of renal clearance and estradiol
    Arne Reimers
    Department of Clinical Pharmacology, St Olavs University Hospital, 7006 Trondheim, Norway Department of Neuroscience, Faculty of Medicine, Norwegian University of Science and Technology NTNU, 7489 Trondheim, Norway
    Epilepsy Res 94:198-205. 2011
    ..To investigate the physiological mechanisms behind the pronounced decline of lamotrigine (LTG) serum concentrations during pregnancy...
  14. ncbi request reprint Seizure control and pharmacokinetics of antiepileptic drugs in pregnant women with epilepsy
    Eylert Brodtkorb
    Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway
    Seizure 17:160-5. 2008
    ..Education concerning reproductive issues is an essential part of the epilepsy service to fertile women...
  15. doi request reprint [Do urine tests for drugs of abuse cover the substances of interest?]
    Roar Dyrkorn
    Avdeling for klinisk farmakologi, St Olavs Hospital, 7006 Trondheim, Norway
    Tidsskr Nor Laegeforen 131:570-2. 2011
    ..Our laboratory analyses substances with a potential of abuse in about 60,000 urine specimens annually. We wished to find out if our standard panel of analyses can detect most of these substances...
  16. ncbi request reprint Adverse drug reactions of antidepressants and antipsychotics: experience, knowledge and attitudes among Norwegian psychiatrists
    Ingrid Castberg
    Department of Clinical Pharmacology, St Olav University Hospital, Trondheim, Norway
    Nord J Psychiatry 60:227-33. 2006
    ..The knowledge of the underlying mechanisms of ADRs was more or less incomplete. The reporting rate of ADRs to the national regulatory authorities was low...
  17. doi request reprint Is dietary caffeine involved in seizure precipitation?
    Christian Samsonsen
    Department of Neurology and Clinical Neurophysiology, St Olav s University Hospital, Trondheim, Norway
    Epilepsy Behav 28:147-50. 2013
    ..37) or the consumption on a seizure-free day (p = 0.13). Thus, caffeine does not appear to be a common seizure precipitant...
  18. doi request reprint Benzoylated uronic acid building blocks and synthesis of N-uronate conjugates of lamotrigine
    Aslan M Esmurziev
    Norwegian University of Science and Technology NTNU, Trondheim, Norway
    Molecules 17:820-35. 2012
    ..Also methyl (2,3-di-O-benzoyl-4-deoxy-4-fluoro-α-D-glucosyl bromide)uronate underwent N-glucuronidation, but the product was unstable, eliminating hydrogen fluoride to give the corresponding enoate conjugate...
  19. doi request reprint [Dosing of digitoxin in clinical practice]
    Arne Hønnås
    Avdeling for klinisk farmakologi, St Olavs Hospital, 7006 Trondheim, Norway
    Tidsskr Nor Laegeforen 130:1334-6. 2010
    ..In 2007, new Norwegian guidelines suggested that serum concentrations of digitoxin should be in the interval 8 - 15 nmol/l, which is about 50 % lower than previous recommendations...
  20. ncbi request reprint Combined overdose of atomoxetine and methylphenidate in a cytochrome P450 2D6 poor metabolizer
    Arne Reimers
    J Clin Psychopharmacol 27:110-1. 2007