Ingebjørg Seljeflot

Summary

Country: Norway

Publications

  1. pmc Circulating levels of IL-18 are significantly influenced by the IL-18 +183 A/G polymorphism in coronary artery disease patients with diabetes type 2 and the metabolic syndrome: an observational study
    Trine B Opstad
    Center for Clinical Heart Research, Department of Cardiology, Oslo University Hospital, Ulleval, Norway
    Cardiovasc Diabetol 10:110. 2011
  2. pmc Blood cell gene expression associated with cellular stress defense is modulated by antioxidant-rich food in a randomised controlled clinical trial of male smokers
    Siv K Bøhn
    Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Norway
    BMC Med 8:54. 2010
  3. ncbi request reprint Procoagulant activity and cytokine expression in whole blood cultures from patients with atherosclerosis supplemented with omega-3 fatty acids
    I Seljeflot
    Dept of Clinical Chemistry, Ulleval University Hospital, Oslo, Norway
    Thromb Haemost 81:566-70. 1999
  4. ncbi request reprint Effects of doxazosin and atenolol on circulating endothelin-1 and von Willebrand factor in hypertensive middle-aged men
    I Seljeflot
    Research Forum, Ulleval University Hospital, Oslo, Norway
    J Cardiovasc Pharmacol 34:584-8. 1999
  5. ncbi request reprint Reduced expression of endothelial cell markers after long-term transdermal hormone replacement therapy in women with coronary artery disease
    I Seljeflot
    Research Forum, Ulleval University Hospital, Oslo, Norway
    Thromb Haemost 83:944-8. 2000
  6. ncbi request reprint Reduced expression of endothelial cell markers after 1 year treatment with simvastatin and atorvastatin in patients with coronary heart disease
    Ingebjørg Seljeflot
    Center for Clinical Research, Ulleval University Hospital, Oslo, Norway
    Atherosclerosis 162:179-85. 2002
  7. ncbi request reprint Improved fibrinolysis after 1-year treatment with HMG CoA reductase inhibitors in patients with coronary heart disease
    Ingebjørg Seljeflot
    Center for Clinical Research, Ulleval University Hospital, Oslo, Norway
    Thromb Res 105:285-90. 2002
  8. ncbi request reprint Increased levels of soluble tissue factor during long-term treatment with warfarin in patients after an acute myocardial infarction
    I Seljeflot
    Center for Clinical Research, Ulleval University Hospital, Oslo, Norway
    J Thromb Haemost 2:726-30. 2004
  9. ncbi request reprint Soluble tissue factor as predictor of future events in patients with acute myocardial infarction
    Ingebjørg Seljeflot
    Center for Clinical Research, Ulleval University Hospital, Oslo, Norway
    Thromb Res 111:369-72. 2003
  10. doi request reprint The influence of intracoronary injection of bone marrow cells on prothrombotic markers in patients with acute myocardial infarction
    Svein Solheim
    Center for Clinical Heart Research, Oslo University Hospital, Ulleval, Oslo, Norway
    Thromb Res 130:765-8. 2012

Detail Information

Publications64

  1. pmc Circulating levels of IL-18 are significantly influenced by the IL-18 +183 A/G polymorphism in coronary artery disease patients with diabetes type 2 and the metabolic syndrome: an observational study
    Trine B Opstad
    Center for Clinical Heart Research, Department of Cardiology, Oslo University Hospital, Ulleval, Norway
    Cardiovasc Diabetol 10:110. 2011
    ..The present study investigated the presence and influence of IL-18 genetic variants on gene- and protein expression in stable coronary artery disease (CAD) patients...
  2. pmc Blood cell gene expression associated with cellular stress defense is modulated by antioxidant-rich food in a randomised controlled clinical trial of male smokers
    Siv K Bøhn
    Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Norway
    BMC Med 8:54. 2010
    ..However, the mechanisms behind this protective effect are not elucidated. We have tested the hypothesis that intake of antioxidant-rich foods can affect groups of genes associated with cellular stress defence in human blood cells...
  3. ncbi request reprint Procoagulant activity and cytokine expression in whole blood cultures from patients with atherosclerosis supplemented with omega-3 fatty acids
    I Seljeflot
    Dept of Clinical Chemistry, Ulleval University Hospital, Oslo, Norway
    Thromb Haemost 81:566-70. 1999
    ..001, TNF alpha p = 0.002). The present results indicate a reduction in pro-thrombotic potential in patients receiving highly concentrated n-3 FA, whereas some proinflammatory responses might be adverse...
  4. ncbi request reprint Effects of doxazosin and atenolol on circulating endothelin-1 and von Willebrand factor in hypertensive middle-aged men
    I Seljeflot
    Research Forum, Ulleval University Hospital, Oslo, Norway
    J Cardiovasc Pharmacol 34:584-8. 1999
    ....
  5. ncbi request reprint Reduced expression of endothelial cell markers after long-term transdermal hormone replacement therapy in women with coronary artery disease
    I Seljeflot
    Research Forum, Ulleval University Hospital, Oslo, Norway
    Thromb Haemost 83:944-8. 2000
    ....
  6. ncbi request reprint Reduced expression of endothelial cell markers after 1 year treatment with simvastatin and atorvastatin in patients with coronary heart disease
    Ingebjørg Seljeflot
    Center for Clinical Research, Ulleval University Hospital, Oslo, Norway
    Atherosclerosis 162:179-85. 2002
    ....
  7. ncbi request reprint Improved fibrinolysis after 1-year treatment with HMG CoA reductase inhibitors in patients with coronary heart disease
    Ingebjørg Seljeflot
    Center for Clinical Research, Ulleval University Hospital, Oslo, Norway
    Thromb Res 105:285-90. 2002
    ..The results indicate that the drugs promote a profibrinolytic profile, and may in part explain the benefit of statin treatment rendered in the prevention of CHD...
  8. ncbi request reprint Increased levels of soluble tissue factor during long-term treatment with warfarin in patients after an acute myocardial infarction
    I Seljeflot
    Center for Clinical Research, Ulleval University Hospital, Oslo, Norway
    J Thromb Haemost 2:726-30. 2004
    ..However, significantly reduced levels of the coagulation products were obtained, indicating reduced thrombin generation. The increased levels of sTF during warfarin therapy are suggested to appear on the basis of reduced consumption...
  9. ncbi request reprint Soluble tissue factor as predictor of future events in patients with acute myocardial infarction
    Ingebjørg Seljeflot
    Center for Clinical Research, Ulleval University Hospital, Oslo, Norway
    Thromb Res 111:369-72. 2003
  10. doi request reprint The influence of intracoronary injection of bone marrow cells on prothrombotic markers in patients with acute myocardial infarction
    Svein Solheim
    Center for Clinical Heart Research, Oslo University Hospital, Ulleval, Oslo, Norway
    Thromb Res 130:765-8. 2012
    ..The aim of the present substudy of the autologous stem cell transplantation in acute myocardial infarction (ASTAMI) trial was to investigate the influence of intracoronary injection of mBMC on selected circulating prothrombotic markers...
  11. pmc Increased levels of CRP and MCP-1 are associated with previously unknown abnormal glucose regulation in patients with acute STEMI: a cohort study
    Eva C Knudsen
    Center for Clinical Heart Research, Oslo University Hospital, Ulleval, Oslo, Norway
    Cardiovasc Diabetol 9:47. 2010
    ....
  12. ncbi request reprint Influence of long-term intervention with dietary counseling, long-chain n-3 fatty acid supplements, or both on circulating markers of endothelial activation in men with long-standing hyperlipidemia
    Elsa M Hjerkinn
    Center for Clinical Research, Ullevaal University Hospital, Oslo, Norway
    Am J Clin Nutr 81:583-9. 2005
    ..Elevated concentrations of circulating cell adhesion molecules, thrombomodulin (TM), von Willebrand factor (vWF), and tissue-type plasminogen activator antigen (tPAag) are related to atherothrombotic cardiovascular disease...
  13. ncbi request reprint Inflammatory and thrombotic markers in patients with ST-elevation myocardial infarction treated with thrombolysis and early PCI: a NORDISTEMI substudy
    Sigrun Halvorsen
    Department of Cardiology, Oslo University Hospital Ulleval, Oslo, Norway
    Thromb Res 130:495-500. 2012
    ..Furthermore, we wanted to study if levels of markers were related to infarct size...
  14. ncbi request reprint Effect of diet or very long chain omega-3 fatty acids on progression of atherosclerosis, evaluated by carotid plaques, intima-media thickness and by pulse wave propagation in elderly men with hypercholesterolaemia
    Elsa M Hjerkinn
    Centre for Clinical Research, Ullevaal University Hospital, Oslo, Norway
    Eur J Cardiovasc Prev Rehabil 13:325-33. 2006
    ..4 g/day) on the progression of atherosclerosis in carotid arteries and on finger pulse wave propagation...
  15. doi request reprint Reduced platelet function and role of drugs in acute gastrointestinal bleeding
    Marianne K Kringen
    Department of Pharmacology, Oslo University Hospital, Ulleval, Kirkeveien 166, Oslo, Norway
    Basic Clin Pharmacol Toxicol 108:194-201. 2011
    ..In conclusion, platelet function is reduced in acute GI bleeding patients and a considerable proportion appears to be related to drug use...
  16. doi request reprint L-arginine, asymmetric dimethylarginine and rhythm outcome after electrical cardioversion for atrial fibrillation
    Arnljot Tveit
    Department of Internal Medicine, Baerum Hospital, Vestre Viken Hospital Trust, Oslo, Norway
    Cardiology 117:176-80. 2010
    ....
  17. ncbi request reprint Relationship between obesity, smoking, and the endogenous nitric oxide synthase inhibitor, asymmetric dimethylarginine
    Hilde M A Eid
    Center for Clinical Research, Ullevaal University Hospital, NO 0407 Oslo, Norway
    Metabolism 53:1574-9. 2004
    ..The beneficial dimethylarginine profile observed in smokers in this elderly population is not easily explainable and should be further investigated...
  18. doi request reprint The effect of exercise on serum levels of interleukin-18 and components of the metabolic syndrome
    Marius Trøseid
    Center for Clinical Heart Research, Department of Cardiology, Oslo University Hospital, Ulleval, Oslo, Norway
    Metab Syndr Relat Disord 7:579-84. 2009
    ..Pravastatin was used for comparison...
  19. ncbi request reprint Markers of endothelial and platelet activation are associated with high on-aspirin platelet reactivity in patients with stable coronary artery disease
    Alf Age R Pettersen
    Center for Clinical Heart Research, Oslo University Hospital, Ullevaal, Oslo, Norway
    Thromb Res 130:424-8. 2012
    ..Aspirin inhibits the cyclooxygenase-1 (COX-1) mediated thromboxane A2 synthesis. Despite COX-1 inhibition, in patients with coronary artery disease (CAD), platelets can be activated through other mechanisms, like activation by thrombin...
  20. pmc The role of interleukin-18 in the metabolic syndrome
    Marius Trøseid
    Center for Clinical Heart Research, Department of Cardiology, Oslo University Hospital, Ulleval, Oslo, Norway
    Cardiovasc Diabetol 9:11. 2010
    ..The purpose of this review is to outline the role of IL-18 in the metabolic syndrome, with particular emphasis on cardiovascular risk and the potential effect of life style interventions...
  21. doi request reprint Circulating CD34⁺ progenitor cells and growth factors in patients treated with PCI for acute myocardial infarction or stable angina pectoris
    Haakon K Grøgaard
    Department of Cardiology, Oslo University Hospital, Ulleval, Oslo, Norway
    Scand J Clin Lab Invest 71:322-9. 2011
    ..To differentiate the effect of myocardial infarction from the effect of percutaneous coronary intervention (PCI) on the circulatory profiles of CD34(+) cells and growth factors in patients with ST-elevation myocardial infarction (STEMI)...
  22. pmc Activin A levels are associated with abnormal glucose regulation in patients with myocardial infarction: potential counteracting effects of activin A on inflammation
    Geir Ø Andersen
    Department of Cardiology, Oslo University Hospital Ulleval, Oslo, Norway
    Diabetes 60:1544-51. 2011
    ..On the basis of the role of activin A in inflammation, atherogenesis, and glucose homeostasis, we investigated whether activin A could be related to glucometabolic abnormalities in patients with acute myocardial infarction (MI)...
  23. ncbi request reprint Cell treatment after acute myocardial infarction prevents early decline in circulating IGF-1
    Haakon K Grøgaard
    Institute for Experimental Medical Research, Oslo University Hospital, Ulleval, University of Oslo, Oslo, Norway
    Scand Cardiovasc J 44:267-72. 2010
    ..To examine the influence of intracoronary autologous bone marrow cell transplantation after acute myocardial infarction on circulating growth factors and their relationship to left ventricular function...
  24. ncbi request reprint Inflammatory responses after intracoronary injection of autologous mononuclear bone marrow cells in patients with acute myocardial infarction
    Svein Solheim
    Department of Cardiology, Ulleval University Hospital, Oslo, Norway
    Am Heart J 155:55.e1-9. 2008
    ..The aim of this study was to investigate the influence of intracoronary injection of mBMC on inflammatory mediators in patients with acute myocardial infarction (AMI)...
  25. ncbi request reprint Effect of lifestyle and/or statin treatment on soluble markers of atherosclerosis in hypertensives
    Anne Hjelstuen
    Research Forum, Ulleval University Hospital, Oslo, Norway
    Scand Cardiovasc J 41:313-20. 2007
    ..To investigate the independent and combined effects of lifestyle changes and statin treatment on soluble markers of atherosclerotic activity...
  26. ncbi request reprint Occult bleeding in three different antithrombotic regimes after myocardial infarction. A WARIS-II subgroup analysis
    Mette Hurlen
    Ulleval University Hospital, Norway
    Thromb Res 118:433-8. 2006
    ..The accompanying bleeding tendency is a concern. The aim of the present study was to compare the occurrence of occult bleeding and iron deficiency during these treatment modalities...
  27. ncbi request reprint Coagulation factor VII, R353Q polymorphism, and serum choline-containing phospholipids in males at high risk for coronary heart disease
    Anja S Lindman
    Center for Clinical Research, Ulleval University Hospital, Oslo, Norway
    Thromb Res 113:57-65. 2004
    ..The R353Q polymorphism of the FVII gene has been shown to modify plasma levels of FVII, and has in some studies also been associated with reduced risk for MI...
  28. ncbi request reprint No difference in the effects of clopidogrel and aspirin on inflammatory markers in patients with coronary heart disease
    Svein Solheim
    Clinical Cardiovascular Research Unit, Department of Cardiology, Ulleval University Hospital, Oslo, Norway
    Thromb Haemost 96:660-4. 2006
    ..The present results indicate similar anti-inflammatory effects of the two drugs...
  29. pmc Abnormal glucose regulation in patients with acute ST- elevation myocardial infarction-a cohort study on 224 patients
    Eva C Knudsen
    Center for Clinical Heart Research, Ulleval University Hospital, University of Oslo, Oslo, Norway
    Cardiovasc Diabetol 8:6. 2009
    ....
  30. pmc Impact of newly diagnosed abnormal glucose regulation on long-term prognosis in low risk patients with ST-elevation myocardial infarction: A follow-up study
    Eva C Knudsen
    Center for Clinical Heart Research, Oslo University Hospital, Ulleval, Oslo, Norway
    BMC Endocr Disord 11:14. 2011
    ..abstract:..
  31. doi request reprint Amino-terminal pro-B-type natriuretic peptide (NT-proBNP) levels 3 months after myocardial infarction are more strongly associated with magnetic resonance-determined ejection fraction than NTproBNP levels in the acute phase
    Nisha Mistry
    Department of Cardiology, Oslo University Hospital, Oslo, Norway
    J Card Fail 17:479-86. 2011
    ....
  32. ncbi request reprint Influence of aspirin on inflammatory markers in patients after acute myocardial infarction
    Svein Solheim
    Department of Cardiology, Ulleval University Hospital, Oslo, Norway
    Am J Cardiol 92:843-5. 2003
    ..However, the same levels were not predictors for clinical end points...
  33. ncbi request reprint Inflammatory responses after percutaneous coronary intervention in patients with acute myocardial infarction or stable angina pectoris
    S Solheim
    Department of Cardiology, Ulleval University Hospital, Oslo, Norway
    Scand J Clin Lab Invest 68:555-62. 2008
    ..To investigate the profile of circulating inflammatory markers after percutaneous coronary intervention (PCI) in patients with AMI or stable angina pectoris (AP)...
  34. doi request reprint The influence of tissue factor and tissue factor pathway inhibitor polymorphisms on thrombin generation in stable coronary artery disease
    Trine B Opstad
    Department of Cardiology, Center for Clinical Heart Research, Oslo University Hospital, Oslo, Norway
    Pathophysiol Haemost Thromb 37:98-103. 2010
    ..05) and additionally time to peak (p = 0.06). Strong correlations between TFPI levels, prothrombin fragment 1 and 2 as well as calibrated automated thrombogram parameters were observed...
  35. doi request reprint Dairy products and metabolic effects in overweight men and women: results from a 6-mo intervention study
    Marianne Hauge Wennersberg
    Department of Nutrition, University of Oslo, Oslo, Norway
    Am J Clin Nutr 90:960-8. 2009
    ..Some epidemiologic studies have suggested inverse relations between intake of dairy products and components of the metabolic syndrome...
  36. pmc Prothrombotic markers in patients with acute myocardial infarction and left ventricular thrombus formation treated with pci and dual antiplatelet therapy
    Svein Solheim
    Center for Clinical Heart Research, Department of Cardiology, Oslo University Hospital, Ulleval, Postbox 4956, Nydalen, 0424, Oslo, Norway
    Thromb J 11:1. 2013
    ..abstract:..
  37. doi request reprint The L-arginine-asymmetric dimethylarginine ratio is strongly related to the severity of chronic heart failure. No effects of exercise training
    Ingebjørg Seljeflot
    Center for Clinical Heart Research, Department of Cardiology, Oslo University Hospital Ulleval, Oslo, Norway
    J Card Fail 17:135-42. 2011
    ..The effect of 4 months' group-based exercise training was further investigated...
  38. doi request reprint Vitamin C consumption is associated with less progression in carotid intima media thickness in elderly men: A 3-year intervention study
    Ingrid Ellingsen
    Department of Preventive Cardiology, Ulleval University Hospital, Oslo, Norway
    Nutr Metab Cardiovasc Dis 19:8-14. 2009
    ..Plant foods may lower the risk of cardiovascular disease...
  39. ncbi request reprint The association between metabolic syndrome and infarct size in patients with acute myocardial infarction
    Ellen Bøhmer
    Oslo University Hospital, Ulleval, Department of Cardiology, Oslo, Norway
    Scand J Clin Lab Invest 70:287-93. 2010
    ..We investigated the role of metabolic syndrome and related biomarkers as predictors of infarct size in patients with their first myocardial infarction...
  40. ncbi request reprint Do novel risk factors differ between men and women aged 18 to 39 years with a high risk of coronary heart disease?
    Serena Tonstad
    Department of Preventive Cardiology, Center for Preventive Medicine, Ulleval University Hospital, Oslo, Norway
    Metabolism 56:260-6. 2007
    ..Lifestyle factors including body mass index, dietary sucrose, smoking, and hormones were associated with levels of the markers independent of sex with body mass index being the most prominent factor...
  41. ncbi request reprint Fractalkine levels are elevated early after PCI-treated ST-elevation myocardial infarction; no influence of autologous bone marrow derived stem cell injection
    Ida Unhammer Njerve
    Center for Clinical Heart Research, Department of Cardiology, Oslo University Hospital Ullevaal, Oslo, Norway Center for Heart Failure Research, Oslo University Hospital, Oslo, Norway Faculty of Medicine, University of Oslo, Oslo, Norway Electronic address
    Cytokine 69:131-5. 2014
    ....
  42. pmc Effects of omega 3 supplementation in elderly patients with acute myocardial infarction: design of a prospective randomized placebo controlled study
    Kristian Laake
    Center for Clinical Heart Research, Oslo University Hospital, Ulleval, Oslo, Norway
    BMC Geriatr 14:74. 2014
    ..We present the design of the OMEMI (OMega-3 fatty acids in Elderly patients with Myocardial Infarction) study...
  43. pmc Warfarin dose and INR related to genotypes of CYP2C9 and VKORC1 in patients with myocardial infarction
    Kari Bente Foss Haug
    R and D, Department of Clinical Chemistry, Ulleval University Hospital, Kirkeveien 166, O407 Oslo, Norway
    Thromb J 6:7. 2008
    ....
  44. ncbi request reprint Decreased levels of asymmetric dimethylarginine during acute hyperinsulinemia
    Hilde Marie Angell Eid
    Center for Clinical Research, Department of Cardiology, Ullevaal University Hospital, Oslo, Norway
    Metabolism 56:464-9. 2007
    ..The possible influence of insulin on ADMA levels in a chronic state of insulin resistance can, however, not be deduced from the present investigation...
  45. ncbi request reprint Unstable angina, stroke, myocardial infarction and death in aspirin non-responders. A prospective, randomized trial. The ASCET (ASpirin non-responsiveness and Clopidogrel Endpoint Trial) design
    Alf Age Pettersen
    Department of Cardiology, Ulleval University Hospital, Oslo, Norway
    Scand Cardiovasc J 38:353-6. 2004
    ..Laboratory methods for determination of platelet reactivity and treatment efficacy have been complicated and time consuming. New methodologies, like the PFA-100 system, have made such analyses more suitable for clinical use...
  46. ncbi request reprint Serum non-esterified very long-chain PUFA are associated with markers of endothelial dysfunction
    Paula Yli-Jama
    Institute for Nutrition Research, University of Oslo, PO Box 1046, Blindern, N 0316, Oslo, Norway
    Atherosclerosis 164:275-81. 2002
    ..The inverse relation between the levels of sVCAM-1 and very long-chain n-3 fatty acids might indicate an anti-inflammatory effect of the latter...
  47. doi request reprint Elevated serum osteoprotegerin levels measured early after acute ST-elevation myocardial infarction predict final infarct size
    Geir Øystein Andersen
    Department of Cardiology, Oslo University Hospital Ulleval, Oslo, Norway
    Heart 97:460-5. 2011
    ..The outcome variable final infarct size was dichotomised using the 75th percentile as the cutoff value (large infarct size ≥ 29.0%). A multivariable analysis was performed adjusting for multiple clinical and biochemical covariates...
  48. ncbi request reprint Altered hemostatic balance and endothelial activation in pregnant women with familial hypercholesterolemia
    Agot L Amundsen
    Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
    Thromb Res 120:21-7. 2007
    ..However, whether hemostatic and endothelial activation markers are increased in pregnant FH women compared with non-FH pregnancies, is unknown...
  49. doi request reprint Fractalkine and its receptor (CX3CR1) in patients with stable coronary artery disease and diabetes mellitus
    Ida Unhammer Njerve
    Center for Clinical Heart Research, Department of Cardiology, Oslo University Hospital, Ullevaal, Oslo, Norway
    Metab Syndr Relat Disord 10:400-6. 2012
    ..We investigated whether CAD patients with T2DM or metabolic syndrome have increased circulating and gene expression levels of fractalkine compared to CAD patients without these conditions...
  50. pmc Markers of hypercoagulability in CAD patients. Effects of single aspirin and clopidogrel treatment
    Vibeke Bratseth
    Department of Cardiology, Center for Clinical Heart Research, Oslo University Hospital Ulleval, PB 4956 Nydalen, Oslo, N 0424, Norway
    Thromb J 10:12. 2012
    ..abstract:..
  51. ncbi request reprint Increased levels of asymmetric dimethylarginine in populations at risk for atherosclerotic disease. Effects of pravastatin
    Hilde M Eid
    Center for Clinical Research, Ullevaal University Hospital, Oslo, Norway
    Atherosclerosis 166:279-84. 2003
    ..Treatment with pravastatin 40 mg/day for 8 weeks had no effect on the levels of ADMA in hypercholesterolemic men...
  52. ncbi request reprint Prothrombotic activity is associated with the anatomical as well as the functional severity of peripheral arterial occlusive disease
    Marthe Nylaende
    Department of Vascular Surgery, Aker University Hospital, Oslo, Norway
    Thromb Haemost 95:702-7. 2006
    ..These findings demonstrate a prothrombotic state in PAD patients, which might be of importance in future diagnosis and treatment of the disease...
  53. doi request reprint Renal tubulointerstitial expansion is associated with endothelial dysfunction and inflammation in type 1 diabetes
    Hans Jacob Bangstad
    Department of Paediatrics, Ulleval University Hospital, Oslo, Norway
    Scand J Clin Lab Invest 69:138-44. 2009
    ..We investigated whether reactive oxidative species, pro-inflammatory cytokines and endothelial dysfunction were implicated in the progression of tubulointerstitial damage in young subjects with type 1 diabetes...
  54. pmc Interleukin-18 is a strong predictor of cardiovascular events in elderly men with the metabolic syndrome: synergistic effect of inflammation and hyperglycemia
    Marius Trøseid
    Center for Clinical Heart Research, Department of Cardiology, University of Oslo, Oslo, Norway
    Diabetes Care 32:486-92. 2009
    ..The aim of this study was to investigate the role of inflammatory markers as potential predictors of cardiovascular events in subjects with and without the metabolic syndrome...
  55. ncbi request reprint Effect of lifestyle changes on atherogenic lipids and endothelial cell adhesion molecules in young adults with familial premature coronary heart disease
    Serena Tonstad
    Department of Preventive Cardiology, Center for Clinical Research, Ulleval University Hospital, Oslo, Norway
    Am J Cardiol 95:1187-91. 2005
    ..05 between groups). These findings indicate that dietary modification and smoking cessation are feasible in young adults with familial premature CHD and document novel mechanisms by which lifestyle modification may reduce CHD risk...
  56. pmc The co-existence of the IL-18+183 A/G and MMP-9 -1562 C/T polymorphisms is associated with clinical events in coronary artery disease patients
    Trine B Opstad
    Center for Clinical Heart Research, Department of Cardiology, Oslo University Hospital, Ulleval, Oslo, Norway Center for Heart Failure Research, Oslo University Hospital, Oslo, Norway
    PLoS ONE 8:e74498. 2013
    ..Serum levels of IL-18, MMP-9 and tissue inhibitor of matrix metalloproteinase (TIMP)-1 were additionally assessed...
  57. ncbi request reprint The predictive value of transthoracic echocardiographic variables for sinus rhythm maintenance after electrical cardioversion of atrial fibrillation. Results from the CAPRAF study, a prospective, randomized, placebo-controlled study
    Irene Grundvold
    Department of Cardiology, Ulleval University Hospital, Oslo, Norway
    Cardiology 111:30-5. 2008
    ..The aim of the present study was to prospectively investigate if standard echocardiographic variables at the day of cardioversion could predict sinus rhythm maintenance...
  58. doi request reprint Compliance, tolerability and safety of two antioxidant-rich diets: a randomised controlled trial in male smokers
    Anette Karlsen
    Department of Nutrition, Faculty of Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
    Br J Nutr 106:557-71. 2011
    ..Such diets may be useful in future studies investigating whether dietary antioxidants may reduce oxidative stress and related diseases...
  59. pmc Genetic variation of VKORC1 and CYP4F2 genes related to warfarin maintenance dose in patients with myocardial infarction
    Marianne K Kringen
    Department of Pharmacology, Oslo University Hospital, Ulleval, Oslo, Norway
    J Biomed Biotechnol 2011:739751. 2011
    ..Our results indicate that pharmacogenetic testing for VKORC1*2, CYP2C9*2 and CYP2C9*3 is more informative regarding warfarin dose requirements than testing for VKORC1*3, VKORC1*4, and CYP4F2 (1347 C > T) polymorphisms...
  60. ncbi request reprint Insulin and adiponectin inhibit the TNFalpha-induced ADMA accumulation in human endothelial cells: the role of DDAH
    Hilde Marie Angell Eid
    Center for Clinical Research, Ullevaal University Hospital, Oslo, Norway
    Atherosclerosis 194:e1-8. 2007
    ..Insulin and adiponectin exert important effects on the vasculature. We wanted to explore whether the eNOS inhibitor asymmetric dimethylarginine (ADMA) contribute to their effects...
  61. pmc The effects of long-term oral benfotiamine supplementation on peripheral nerve function and inflammatory markers in patients with type 1 diabetes: a 24-month, double-blind, randomized, placebo-controlled trial
    David A Fraser
    Diabetes Research Centre, Oslo University Hospital, Oslo, Norway
    Diabetes Care 35:1095-7. 2012
    ..To study the effects of long-term oral benfotiamine supplementation on peripheral nerve function and soluble inflammatory markers in patients with type 1 diabetes...
  62. pmc Gender differences of polymorphisms in the TF and TFPI genes, as related to phenotypes in patients with coronary heart disease and type-2 diabetes
    Trine B Opstad
    Center for Clinical Heart Research, Department of Cardiology, Oslo University Hospital Ulleval, Oslo, Norway
    Thromb J 8:7. 2010
    ..These genotypes and the phenotypes (TF, TFPI free and total antigen) were evaluated with special reference to gender and diabetes in the CHD population...
  63. ncbi request reprint The anesthesia in abdominal aortic surgery (ABSENT) study: a prospective, randomized, controlled trial comparing troponin T release with fentanyl-sevoflurane and propofol-remifentanil anesthesia in major vascular surgery
    Espen E Lindholm
    Senior Consultant Anesthetist, Clinical Nurse Specialist and Research Assistant, Department of Anesthesiology, Senior Consultant Cardiologist, Department of Cardiology, Vestfold Hospital Trust, Tønsberg, Norway Consultant Cardiologist, Center for Cardiological Innovation, Oslo University Hospital, Rikshospitalet, Oslo, Norway Professor, Clinical Cardiovascular Translational Research, Center for Clinical Heart Research, Department of Cardiology, Oslo University Hospital, Ulleval, Norway and Faculty of Medicine, University of Oslo, Oslo, Norway Senior Consultant Vascular Surgeon, Scandinavian Venous Centre, Oslo, Norway Faculty of Medicine, University of Oslo and Clinical Professor in Anesthesiology, Department of Anesthesiology, Oslo University Hospital, Ulleval, Norway
    Anesthesiology 119:802-12. 2013
    ..The aim of the current study was to compare increased troponin T (TnT) values in patients receiving sevoflurane-based anesthesia or total intravenous anesthesia in elective abdominal aortic surgery...
  64. doi request reprint Proinflammatory cytokines and complement activation in salvaged blood from abdominal aortic aneurism surgery and total hip replacement surgery
    Espen Lindholm
    Department of Anesthesiology, Vestfold Hospital Trust, Tønsberg, Norway
    Transfusion 52:1761-9. 2012
    ..We hypothesized that there are higher levels of these mediators in unwashed blood salvaged in AAA surgery compared to hip replacement surgery...