Research Topics
Species | Olav ReikerasSummaryAffiliation: Rikshospitalet University Hospital Country: Norway Publications
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Detail Information
Publications
Reduced tibial torsion in congenital clubfoot: CT measurements in 24 patientsO Reikeras
Orthopaedic University Clinic, National Hospital, Olso, Norway
Acta Orthop Scand 72:53-6. 2001..002). This study shows that there are great variations in leg torsion in children with congenital clubfoot and, on average, the external torsion is significantly lower than in healthy subjects...
Excellent results with femoral revision surgery using an extensively hydroxyapatite-coated stem: 59 patients followed for 10-16 yearsOlav Reikeras
Orthopaedics and Radiological Department, Rikshospitalet University Clinic, Oslo, Norway
Acta Orthop 77:98-103. 2006..We report long-term outcome of a grit-blasted titanium stem entirely plasma sprayed with hydroxyapatite (HA), in femoral revision surgery...
Differences in LPS and PepG induced release of inflammatory cytokines in orthopedic traumaOlav Reikeras
Department of Orthopaedics, Rikshospitalet University Clinic, University of Oslo, Norway
J Invest Surg 21:255-60. 2008....
Time course of thrombosis and fibrinolysis in total knee arthroplasty with tourniquet application. Local versus systemic activationsOlav Reikeras
Department of Orthopaedics, Rikshospitalet University Clinic, University of Oslo, 0027, Oslo, Norway
J Thromb Thrombolysis 28:425-8. 2009..Prophylactic treatment is used up to 12 h before or after surgery, and recent clinical trials suggest that the timing of initiating prophylaxis significantly influences antithrombotic effectiveness...
Hydroxyapatite enhances long-term fixation of titanium implantsOlav Reikeras
Institute of Clinical Medicine, Rikshospitalet University Clinic, University of Oslo, Norway
J Long Term Eff Med Implants 16:165-73. 2006..001) increase in bone bonding contact from 6 to 12 months of the HA coated nails and significantly (p = 0.043) enhanced bone bonding contact in HA coated nails at 12 months as compared to pure titanium nails...
Long-term results of HA coated threaded versus HA coated hemispheric press fit cups: 287 hips followed for 11 to 16 yearsOlav Reikeras
Orthopaedic Department, Rikshospitalet University Clinic, 0027 Oslo, Norway
Arch Orthop Trauma Surg 126:503-8. 2006..In this paper, we report 11 to 16 years follow up results of HA coated threaded versus HA coated hemispherical press fit cups...
Healing of long-term frozen orthotopic bone allografts is not affected by MHC differences between donor and recipientOlav Reikeras
Department of Orthopaedics, Oslo University Hospital, Rikshospitalet, 0027 Oslo, Norway
Clin Orthop Relat Res 469:1479-86. 2011..In particular it remains unclear whether differences in the major histocompatibility complex (MHC) influence incorporation of bone allografts and their subsequent biologic performance...
Systemic and local cytokine kinetics in musculoskeletal injury: a prospective study in patients with ankylosing spondylitisO Reikeras
Department of Orthopedics, Rikshospitalet University Clinic, University of Oslo, Oslo, Norway
Scand J Clin Lab Invest 69:198-203. 2009....
Immunmodulation of serum in orthopaedic traumaOlav Reikeras
Department of Orthopaedics, Rikshospital University Clinic, University of Oslo, Norway
J Trauma 67:624-7. 2009..The aim of this study was to test the hypothesis that inhibitory substances circulating in the patient's serum after trauma might impair leukocyte function by evaluating the effect of such serum on cytokine release in a whole blood model...
Staphylococcus aureus peptidoglycan impairs fracture healing: an experimental study in ratsOlav Reikeras
Department of Orthopaedics, Rikshospitalet Radiumhospitalet Medical Centre, University of Oslo, N 0027 Oslo, Norway
J Orthop Res 25:262-6. 2007..Collectively, these data show that SaPG induces an alteration in the normal bone healing response towards a less calcified callus production...
Impact of MHC mismatch and freezing on bone graft incorporation: an experimental study in ratsOlav Reikeras
Department of Orthopaedics, Rikshospitalet Radiumhospitalet Medical Centre, N 0027 Oslo, Norway
J Orthop Res 26:925-31. 2008....
Postoperative serum attenuates LPS-induced release of TNF-alpha in orthopaedic surgeryOlav Reikeras
Department of Orthopaedics, Rikshospitalet Radiumhospitalet Medical Centre, University of Oslo, N 0027 Oslo, Norway
J Orthop Res 25:1395-400. 2007..The potent TNF-alpha inhibitory activity found at day 6 after injury correlated with increased levels of PGE2 and indicates cell-mediated hyporesponsiveness to a second stimulus...
Lipopolysaccharide impairs fracture healing: an experimental study in ratsOlav Reikeras
Department of Orthopaedics, Rikshospitalet University Clinic, Norway
Acta Orthop 76:749-53. 2005..We investigated the effects of systemic and local administration of LPS on the healing of femoral fractures in rats...
Effects of high-dose corticosteroids on post-traumatic inflammatory mediatorsOlav Reikeras
Department of Orthopaedics, Rikshospitalet University Clinic, University of Oslo, Norway
Inflamm Res 58:891-7. 2009..It was our hypothesis that corticosteroids would reduce the post-operative levels of inflammatory mediators in patients with ankylosing spondylitis, and we performed a single-centre randomised controlled trial...
Impact of freezing on immunology and incorporation of bone allograftOlav Reikeras
Faculty Division Rikshospitalet, Department of Orthopaedics, University of Oslo, N 0027 Oslo, Norway
J Orthop Res 28:1215-9. 2010..This study indicates that in the long run there are no significant consequences; either immunological or biomechanical, of the use of deep frozen allogenous bone as compared to fresh autogenous bone grafts in this animal model...
Failure of HA coating on a gritblasted acetabular cup: 155 patients followed for 7-10 yearsOlav Reikeras
Surgical Department, Sophies Minde, Oslo Orthopaedic University Clinic, Norway
Acta Orthop Scand 73:104-8. 2002..At revision, we found that the soft tissues were discolored, and that most of the coating had disappeared. This design of hydroxyapatite-coated cups has a high rate of debonding and failure...
Immune depression in musculoskeletal traumaOlav Reikeras
Department of Orthopaedics, Rikshospitalet University Clinic, University of Oslo, 0027 Oslo, Norway
Inflamm Res 59:409-14. 2010..e. initial stabilisation of long bone fractures by external fixation followed by definitive stabilisation at about 1 week...
Femoral shortening in total hip arthroplasty for high developmental dysplasia of the hipOlav Reikeras
Department of Orthopedics, Rikshospitalet University Clinic, University of Oslo, 0027, Oslo, Norway
Clin Orthop Relat Res 468:1949-55. 2010..Subtrochanteric femoral osteotomy and shortening makes reduction easier but can be associated with complications (eg, limp, sciatic nerve injury, nonunion of the osteotomy) or compromise long-term stem survival...
Components anteversion in primary cementless THA using straight stem and hemispherical cup: a prospective study in 91 hips using CT-scan measurementsO Reikeras
Orthopaedic and Radiological Departments, Oslo University Hospital, Rikshospitalet, 0027 Oslo, Norway
Orthop Traumatol Surg Res 97:615-21. 2011..The recommended range of anteversion of the components in total hip arthroplasty (THA) is between 10 and 30°, but the intraoperative estimation of these versions may be inadequate...
Excellent results of HA coating on a grit-blasted stem: 245 patients followed for 8-12 yearsOlav Reikeras
Surgical and Radiological Departments, Sophies Minde, National Hospital, NO 0027 Oslo, Norway
Acta Orthop Scand 74:140-5. 2003..The changes in the bone confirmed that the femoral component was well fixed in asymptomatic patients. To conclude, we found excellent 8-12-year results with a fully HA-coated femoral prosthesis designed for press-fit insertion...
Thrombosis markers in hip versus knee arthroplasty: a pilot studyOlav Reikeras
Department of Orthopaedics, Rikshospitalet University Clinic, University of Oslo, Norway
J Orthop Surg (Hong Kong) 17:291-5. 2009..To compare the thrombosis markers for thrombosis and fibrinolysis in patients undergoing hip versus knee arthroplasty...
Bone ingrowths to press-fit and loose-fit implants: comparisons between titanium and hydroxyapatiteOlav Reikeras
Institute of Clinical Medicine, Rikshospitalet University Clinic, University of Oslo, Oslo, Norway
J Long Term Eff Med Implants 16:157-64. 2006..However, due to large variations between the samples, the differences did not reach significant levels...
Hydroxyapatite and carbon coatings for fixation of unloaded titanium implantsOlav Reikeras
Institute of Clinical Medicine, Rikshospitalet University Clinic, University of Oslo, Oslo, Norway
J Long Term Eff Med Implants 14:443-54. 2004..In conclusion, we found great variability in bone bonding contact. In general, carbon-coated nails had reduced bone bonding contact both at 8 and at 16 weeks as compared to pure titanium or titanium coated with hydroxyapatite...
Four-year follow-up of surgical versus non-surgical therapy for chronic low back painJens Ivar Brox
Orthopaedic Department, Oslo University Hospital Rikshospitalet, Sognsvannsveien, 0027 Oslo, Norway
Ann Rheum Dis 69:1643-8. 2010..To compare the long-term effectiveness of surgical and non-surgical treatment in patients with chronic low back pain...
The influence of compression on the healing of experimental tibial fracturesUlf Sigurdsen
Department of Orthopaedic Surgery, University of Oslo, Oslo, Norway
Injury 42:1152-6. 2011..We therefore evaluated the effect of a clinically practicable application of a mechanical compressive interfragmentary stimulus on the healing of experimental tibial diaphyseal fractures...
Poor muscle coverage delays fracture healing in ratsStein Erik Utvag
Department of Orthopedic Surgery, Institute of Clinical Medicine, University Hospital of Tromsø, Norway
Acta Orthop Scand 73:471-4. 2002..This animal study indicates that in tibial fractures, an extensive muscle tissue defect may have negative effects on early bone healing...
Predictors of change in trunk muscle strength for patients with chronic low back pain randomized to lumbar fusion or cognitive intervention and exercisesAnne Keller
Department of Physical Medicine and Rehabilitation, Ulleval University Hospital, Oslo, Norway
Pain Med 9:680-7. 2008....
Conversion of external fixation to definitive intramedullary nailing in experimental tibial fracturesUlf Sigurdsen
Department of Orthopaedic Surgery, Faculty of Medicine, University of Oslo, Norway and Institute of Surgical Research, Oslo University Hospital Rikshospitalet, Norway
J Invest Surg 23:142-8. 2010..The aim of the study was to compare definitive treatment of experimental tibial fractures with external fixation to an early conversion to secondary intramedullary nailing with large and small diameter nails...
Genetic contribution of catechol-O-methyltransferase variants in treatment outcome of low back pain: a prospective genetic association studyAhmad Omair
Department of Orthopaedics, Oslo University Hospital Rikshospitalet, Oslo, Norway
BMC Musculoskelet Disord 13:76. 2012....
Correlations between strength and quantitative computed tomography measurement of callus mineralization in experimental tibial fracturesUlf Sigurdsen
Department of Orthopedic Surgery, University of Oslo, Norway
Clin Biomech (Bristol, Avon) 26:95-100. 2011..We therefore studied the correlations between the strength and segmented quantitative computed tomography data of tibial diaphyseal fractures...
Calcium phosphate bone cement: a possible alternative to autologous bone graft. A radiological and biomechanical comparison in rat tibial boneMona I Winge
Department of Orthopaedic Surgery, Rikshospitalet, Oslo University Hospital, Sognsvannveien 20, Oslo, Norway
Arch Orthop Trauma Surg 131:1035-41. 2011..Donor site morbidity is a problem after autologous bone transplantation. An injectable CaP bone cement indicates properties similar to bone...
External fixation compared to intramedullary nailing of tibial fractures in the ratUlf E W Sigurdsen
Department of Orthopedic Surgery, Faculty Division Akershus University Hospital, University of Oslo, Norway
Acta Orthop 80:375-9. 2009..It is not known whether there is a difference in bone healing after external fixation and after intramedullary nailing. We therefore compared fracture healing in rats after these two procedures...
Functional outcome after lumbar closing wedge osteotomy in ankylosing spondylitisJens Ivar Brox
Department of Orthopedics, Rikshospitalet University Hospital and Medical Faculty, University of Oslo, Oslo, Norway
Int Orthop 33:1049-53. 2009..EuroQol improved from 0.42 to 0.69 (p = 0.002) and occiput-to-wall distance from 26 to 18 cm (p = 0.005). Functional outcome was improved after lumbar closing wedge osteotomy in ankylosing spondylitis...
Long-term results after SLAP repair: a 5-year follow-up study of 107 patients with comparison of patients aged over and under 40 yearsCecilie Piene Schrøder
Orthopedic Department, Lovisenberg Deaconal Hospital, Oslo, Norway
Arthroscopy 28:1601-7. 2012..The aims of this prospective cohort study were to assess the long-term results after isolated superior labral repair and to determine whether the results were associated with age...
Influence of extensive muscle injury on fracture healing in rat tibiaStein Erik Utvag
Department of Orthopedic Surgery, Institute of Clinical Medicine, University Hospital of Tromsoe, Oslo, Norway
J Orthop Trauma 17:430-5. 2003..We hypothesized that a severe crush injury of leg muscles might not be as deleterious to fracture healing as total loss of a large muscle segment...
Direct comparison of polyethylene wear in cemented and uncemented acetabular cupsHåvard Bjerkholt
Department of Orthopaedic Surgery, Lovisenberg Deaconal Hospital, Oslo, Norway
J Orthop Traumatol 11:155-8. 2010..We report a direct comparison of wear of a cemented and an uncemented cup with similar design, polyethylene, and sterilization method...
Disability, pain, psychological factors and physical performance in healthy controls, patients with sub-acute and chronic low back pain: a case-control studyJens Ivar Brox
Department of Orthopaedic Surgery, Section for Back Surgery and Physical Medicine and Rehabilitation, National Hospital, Oslo, Norway
J Rehabil Med 37:95-9. 2005..To evaluate the concept of the deconditioning syndrome and to explore factors that may contribute to chronicity...
High frequency distraction improves tissue adaptation during leg lengthening in humansGudrun Trøite Aarnes
National Hospital Orthopaedic Department, Oslo Orthopaedic University Clinic, Rikshospitalet, Norway
J Orthop Res 20:789-92. 2002..Accordingly, high distraction frequency was considered favourable to low frequency, and is recommended in large lengthenings where high force levels are expected...
Ultrasonography of the infant hip: the significance of provokable instability with normal morphologyOlav Reikeras
National Hospital Orthopedic Center, University of Oslo, Norway
Orthopedics 25:833-5. 2002..In all cases, normal hip development was noted with no differences between the two groups. Therefore, sonographically, instability in morphologically normal or immature hips has no clinical significance...
Role of the fibula in lower leg fractures: an in vivo investigation in ratsJoachim Horn
Department of Orthopaedics, Rikshospitalet University Hospital, Sognsvannsveien 20, N0027 Oslo, Norway
J Orthop Res 26:1027-31. 2008....
Local and systemic chemokine patterns in a human musculoskeletal trauma modelDaniel Bastian
Department of Orthopaedics, Oslo University Clinic, Rikshospital, Sognsvannsveien 20, 0027 Oslo, Norway
Inflamm Res 58:483-9. 2009..This prospective study aims to identify differences in local and systemic chemokines kinetics within 24 h of a standardised human surgical trauma (total hip arthroplasty) and their impact on systemic polymorphonuclear cells...
Outcome of undisplaced and moderately displaced femoral neck fracturesKristian Bjørgul
Department of Orthopaedics, Østfold Hospital, Fredrikstad, Norway
Acta Orthop 78:498-504. 2007..We compared the outcome of displaced fractures with good healing potential (moderately displaced fractures) to the outcome of undisplaced fractures treated by internal fixation with 2 parallel screws...
The Effect of timing of conversion from external fixation to secondary intramedullary nailing in experimental tibial fracturesUlf Sigurdsen
Department of Orthopedic Surgery, University of Oslo, Norway
J Orthop Res 29:126-30. 2011..Early conversion procedure did not improve healing compared to control, but was advantageous compared to late conversion (at 2 or 4 weeks) with higher mineralization and superior biomechanical properties...
Treatment outcome of chronic low back pain and radiographic lumbar disc degeneration are associated with inflammatory and matrix degrading gene variants: a prospective genetic association studyAhmad Omair
Department of Orthopaedics, Oslo University Hospital Rikshospitalet, Sognsvannsveien 20, Oslo 0027, Norway
BMC Musculoskelet Disord 14:105. 2013..This study examines the association of these genetic variants with radiographic lumbar disc degeneration and changes in pain and disability at long-term after surgical and cognitive behavioural management...
Biochemical lung, liver and kidney markers and early death among elderly following hip fractureOve Talsnes
Department of Orthopaedics, Sykehuset Innlandet Hospital Trust, Elverum, Norway
Arch Orthop Trauma Surg 132:1753-8. 2012..This study was conducted to assess biological markers on perioperative organ dysfunction and its association with early mortality within 3 months after surgery...
Clinical and biochemical prediction of early fatal outcome following hip fracture in the elderlyOve Talsnes
Department of Orthopaedics, Elverum Central Hospital, Elverum, Norway
Int Orthop 35:903-7. 2011....
Short-term treatment with COX-2 inhibitors does not impair fracture healingStein Erik Utvag
Department of Orthopaedics, Akershus University Hospital, University of Oslo, Oslo, Norway
J Invest Surg 23:257-61. 2010..The effects of cyclooxygenase (COX) inhibition on fracture healing are insufficiently documented, and the aim of this study was to evaluate the effects of nonspecific and specific COX-2 inhibition in the early phase of fracture healing...
Review article: bone transplantation and immune responseHamid Shegarfi
Institute of Basic Medical Sciences, Department of Anatomy, University of Oslo, Norway
J Orthop Surg (Hong Kong) 17:206-11. 2009..However, they generally lack osteoinductive or osteogenic properties and have various effects on bone healing. We present an overview of bone grafts and graft substitutes in clinical use, and the immune responses to allogeneic bone...
No difference in tibial lengthening index by use of Taylor spatial frame or Ilizarov external fixatorLeif Pål Kristiansen
Rikshospitalet Radiumhospitalet Medical Center, Biomechanics Laboratory, Orthopaedic Department, University of Oslo, Oslo, NO 0027, Norway
Acta Orthop 77:772-7. 2006....
Lumbar instrumented fusion compared with cognitive intervention and exercises in patients with chronic back pain after previous surgery for disc herniation: a prospective randomized controlled studyJens Ivar Brox
Department of Orthopedics and Physiotherapy, Rikshospitalet University Hospital and Medical Faculty University in Oslo, Norway
Pain 122:145-55. 2006..For patients with chronic low back pain after previous surgery for disc herniation, lumbar fusion failed to show any benefit over cognitive intervention and exercises...
Systemic and local cytokine kinetics after total hip replacement surgeryD Bastian
Department of Orthopaedics, Rikshospitalet University Clinic, University of Oslo, Oslo, Norway
Eur Surg Res 41:334-40. 2008..Aberrant reactions can lead to a systemic inflammatory response syndrome, with a potentially lethal outcome. Our aim was to investigate the early local cytokine kinetic compared to systemic changes in a standardized surgical trauma...
Investigation of lipopolysaccharide receptor expression on human monocytes after major orthopaedic surgeryD Bastian
Department of Orthopaedics, Faculty of Dentistry, Rikshospitalet Radiumhospitalet Medical Care, University of Oslo, Oslo, Norway
Eur Surg Res 40:239-45. 2008..The receptors CD14 and CD11b are involved in the LPS receptor complex, whereas human lymphocyte antigen (HLA)-DR binds endotoxin peptides. It is still uncertain whether the expression of all these receptors changes after major surgery...
Dislocation after total hip arthroplasty with 28 and 32-mm femoral headEinar Amlie
Department of Orthopaedic Surgery, Lovisenberg Deaconal Hospital, Oslo, Norway
J Orthop Traumatol 11:111-5. 2010..It has been postulated that increasing the femoral head diameter may reduce the risk of dislocation. The purpose of this paper is to report our experiences with a change from a 28 to a 32-mm femoral head...
Outcome after treatment of complications of Gamma nailing: a prospective study of 554 trochanteric fracturesKristian Bjørgul
Department of Orthopaedics, Østfold Hospital, Oslo, Norway
Acta Orthop 78:231-5. 2007..We compared the outcome after reoperation to the outcome after primary surgery with Gamma nailing...
Randomized clinical trial of lumbar instrumented fusion and cognitive intervention and exercises in patients with chronic low back pain and disc degenerationJens Ivar Brox
Department of Orthopedic Surgery, National Hospital, Oslo, Norway
Spine (Phila Pa 1976) 28:1913-21. 2003..Single blind randomized study...
Reliability, agreement and validity of the 1988 version of the Rowe ScoreØystein Skare
Department of Orthopedics, Lovisenberg Deaconal Hospital, Oslo, Norway
J Shoulder Elbow Surg 20:1041-9. 2011..The aim of this study was to evaluate reliability, agreement, and validity of the 1988 version of the Rowe score in patients with superior glenoid labrum lesions (SLAP) or recurrent anterior dislocations...
Systemic and local cytokine patterns during total hip surgeryT Clementsen
Department of Orthopedics, Rikshospitalet University Clinic, Oslo, Norway
Scand J Clin Lab Invest 66:535-42. 2006..558). CONCLUSIONS: The study indicates that a major musculoskeletal operation on otherwise healthy patients is associated with fairly modest reactions of inflammation, both systemically and locally...
Physical and mental health in young adults operated on for idiopathic scoliosisThomas Kibsgård
Institute of Clinical Medicine, Orthopaedic Department, University of Oslo, Rikshospitalet University Clinic, N 0027 Oslo, Norway
J Orthop Sci 9:360-3. 2004..Thus, the surgical procedure was well tolerated and had not traumatized the patient...
Preoperative versus postoperative initiation of dalteparin thromboprophylaxis in THAPål O Borgen
Department of Orthopaedics, Martina Hansens Hospital, Oslo, Norway
Hip Int 20:301-7. 2010..Few thromboembolic events occurred, and these were equally distributed...
Immune modulation after total hip surgery. A prospective ex vivo studyD Bastian
Department of Orthopaedics, Rikshospitalet Radiumhospitalet Medical Center, University of Oslo, Oslo, Norway
Eur Surg Res 39:296-302. 2007..The purpose of this study was to investigate lipopolysaccharide (LPS)-induced releases of tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) in whole blood in patients undergoing total hip replacement...
The normal development of tibial torsionL P Kristiansen
National Hospital Orthopaedic Center, University of Oslo, Norway
Skeletal Radiol 30:519-22. 2001..CONCLUSION: Tibial torsion in children mainly develops during the first 4 years of life. After this the increase was of less clinical significance...
An Association Study of Interleukin 18 Receptor Genes (IL18R1 and IL18RAP) in Lumbar Disc DegenerationAhmad Omair
Department of Orthopaedics, Oslo University Hospital Rikshospitalet, Oslo, Norway
Open Orthop J 6:164-71. 2012....
Differences in external and internal cortical strain with prosthesis in the femurOlav Reikeras
Oslo University Hospital, University of Oslo, Rikshospitalet, NO 0027 Oslo, Norway
Open Orthop J 5:379-84. 2011..Hence, strain at the internal cortex does not correspond and can not be deducted from measured strain at the external cortex...
Hemiarthroplasty in worst cases is better than internal fixation in best cases of displaced femoral neck fractures: a prospective study of 683 patients treated with hemiarthroplasty or internal fixationKristian Bjørgul
Department of Orthopedics, Rikshospitalet University Hospital, Oslo, Norway
Acta Orthop 77:368-74. 2006....
Reliability of computed tomography measurements of paraspinal muscle cross-sectional area and density in patients with chronic low back painAnne Keller
Department of Physical Medicine and Rehabilitation, Ullevaal University Hospital, Oslo, Norway
Spine (Phila Pa 1976) 28:1455-60. 2003..A reliability study was conducted...
LBP and sCD14 patterns in total hip replacement surgery performed during combined spinal/epidural anaesthesiaDaniel Bastian
Department of Orthopaedics, Oslo University Hospital Rikshospitalet, Oslo, Norway
Scand J Clin Lab Invest 71:486-91. 2011..In this study, we aimed to elucidate the physiological reactions to LBP and sCD14 after total hip replacement surgery during spinal/epidural anaesthesia...
