Research Topics
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Publications
Blood viscosity, plasma adrenaline and fasting insulin in hypertensive patients with left ventricular hypertrophy. ICARUS, a LIFE Substudy. Insulin CARotids US ScandinavicaA Høieggen
Department of Internal Medicine, Ullevaal Hospital, University of Oslo, Norway
Blood Press 9:83-90. 2000..We suggest that adrenergic activity may increase hematocrit and viscosity and hence reduce insulin sensitivity...
The impact of serum uric acid on cardiovascular outcomes in the LIFE studyAud Høieggen
Departments of Nephrology and Cardiology, Ullevaal University Hospital, Oslo, Norway
Kidney Int 65:1041-9. 2004..It has been suggested that the LIFE study results may be related to the effects of losartan on serum uric acid (SUA). SUA has been proposed as an independent risk factor for CV morbidity and death...
[Bilateral renal artery stenosis--a cause of acute pulmonary edema]A Høieggen
Nyremedisinsk avdeling Medisinsk divisjon Ullevål sykehus 0407 Oslo
Tidsskr Nor Laegeforen 121:1789-90. 2001..Renal artery stenosis may present as acute pulmonary oedema and be misinterpreted as congestive heart failure. ACE inhibitors and angiotensin-II antagonists are widely used among patients with congestive heart failure and hypertension...
Biphasic effect of epinephrine on blood glucose during hyperinsulinemia in borderline hypertensive young menA Høieggen
Department of Internal Medicine, Ullevaal Hospital, University of Oslo, Norway
Am J Hypertens 14:539-45. 2001..Subjects who are insulin sensitive and have low blood pressure and resting epinephrine levels seem to be less prone to hyperglycemia induced by epinephrine...
Increased forearm blood flow during glucose clamp is related neither to insulin sensitivity nor to hyperinsulinemia in borderline hypertensive young menA Høieggen
Department of Internal Medicine, Ullevaal Hospital, University of Oslo, Norway
Blood Press 8:227-32. 1999..The moderate increases in FBF during insulin infusion with serum concentrations within the physiological range seem to be time-dependent and not caused by hyperinsulinemia...
Effects of hyperinsulinemia on sympathetic responses to mental stressA Høieggen
Department of Internal Medicine, Ullevaal Hospital, University of Oslo, Norway
Am J Hypertens 13:21-8. 2000..Our results suggest that acute hyperinsulinemia during isoglycemic glucose clamp does not interfere with cardiovascular or sympathetic responses to mental stress...
Insulin modifies the glucose response to mental stress independently of forearm blood flowA Høieggen
Department of Internal Medicine, Ullevaal Hospital, University of Oslo, Norway
Blood Press 7:291-8. 1998..It may be speculated whether insulin counteracts unfavourable effects of mental stress and sympathetic activation on glucose metabolism...
Mental stress increases glucose uptake during hyperinsulinemia: associations with sympathetic and cardiovascular responsivenessA Moan
Department of Internal Medicine, Ullevaal Hospital, University of Oslo, Norway
Metabolism 44:1303-7. 1995..008), and increase in HR (by 23 +/- 2 v 15 +/- 2 beats per minute, P = .008) as compared with 15 subjects with unchanged/increased glucose concentration.(ABSTRACT TRUNCATED AT 250 WORDS)..
Improved insulin sensitivity with the angiotensin II-receptor blocker losartan in patients with hypertension and other cardiovascular risk factorsT A Aksnes
Department of Cardiology, Ullevaal University Hospital, Oslo, Norway
J Hum Hypertens 20:860-6. 2006..5 mg/kg/min, P = 0.039). Thus our data suggest that angiotensin II-receptor blockade with losartan improves glucose metabolism at the cellular level beyond what can be expected by the vasodilatation and blood pressure reduction alone...
Relationship between hemorheological factors and insulin sensitivity in normotensive and hypertensive premenopausal womenG Nordby
Department of Internal Medicine, Ullevaal Hospital, University of Oslo, Norway
Am J Hypertens 8:439-44. 1995..These results suggest hemorheologic, and therefore indirectly hemodynamic factors as correlates to insulin sensitivity...
The EWA (estrogen in women with atherosclerosis) study: a randomized study of the use of hormone replacement therapy in women with angiographically verified coronary artery disease. Characteristics of the study population. Effects on lipids and lipoproteiI Os
Department of Medicine, Ulleval University Hospital and Hormone Laboratory, Aker University Hospital, Oslo, Norway
J Intern Med 247:433-41. 2000..To evaluate the effects of hormone replacement therapy (HRT) on lipids and lipoproteins in postmenopausal women with coronary artery disease...
Plasma leptin in postmenopausal women with coronary artery disease: effect of transdermal 17beta-estradiol and intermittent medroxyprogesterone acetateI Os
Department of Pharmacotherapeutics, University of Oslo, Norway
Climacteric 6:204-10. 2003..CONCLUSION: Plasma leptin is related to other cardiovascular risk factors in postmenopausal women with CAD, but seems to be unaffected by transdermal 17beta-estradiol administration...
Autonomic function in hypertensive and normotensive subjects: the importance of genderK Sevre
Department of Cardiology, Ulleval University Hospital, Oslo, Norway
Hypertension 37:1351-6. 2001..Our results suggest that gender is an important determinant of BRS and HRV. Autonomic function parameters were especially impaired in hypertensive women compared with hypertensive men...
Female preponderance for lisinopril-induced cough in hypertensionI Os
Department of Medicine, , Oslo, Norway
Am J Hypertens 7:1012-5. 1994..Similar gender differences were observed during specific questioning. Furthermore, nonsmokers reported an increase in cough more often than did smokers...
Comparison of the combination of enalapril and a very low dose of hydrochlorothiazide with atenolol in patients with mild-to-moderate hypertension. Scandinavian Study GroupI Os
Department of Medicine, Ullevaal University Hospital, Oslo, Norway
Am J Hypertens 10:899-904. 1997..019); there was a trend toward more patients achieving target diastolic BP (<90 mm Hg, P = .053). No clinically important differences in safety and tolerability were observed...
Mild essential hypertension in nonobese premenopausal women is characterized by low reninG Nordby
Department of Internal Medicine, , University of Oslo, Norway
Am J Hypertens 5:579-84. 1992..41, P less than .05). Since low renin hypertension is associated with less cardiovascular complications, this may offer an explanation for the better prognosis of hypertension in women...
Decreased serum phosphate in essential hypertension. Related to increased sympathetic toneS E Kjeldsen
Department of Internal Medicine, Ullevaal Hospital, Oslo, Norway
Am J Hypertens 1:403-9. 1988..Thus, hypophosphatemia in patients with mild essential hypertension appears to be inversely related to sympathetic adrenal tone and may be caused by increased plasma epinephrine within pathophysiologic arterial concentrations...
Effect of dietary counselling on blood pressure and arterial plasma catecholamines in primary hypertensionS L Beckmann
Department of Internal Medicine, Ullevaal Hospital, University of Oslo, Norway
Am J Hypertens 8:704-11. 1995....
Reduced expression of endothelial cell markers after long-term transdermal hormone replacement therapy in women with coronary artery diseaseI Seljeflot
Research Forum, Ulleval University Hospital, Oslo, Norway
Thromb Haemost 83:944-8. 2000....
Blood pressure development and hypertensive retinopathy: 20-year follow-up of middle-aged normotensive and hypertensive menH Gudmundsdottir
Department of Nephrology, Ulleval University Hospital, Oslo, Norway
J Hum Hypertens 24:505-13. 2010....
The effects of hormone replacement therapy on hemostatic variables in women with angiographically verified coronary artery disease: results from the estrogen in women with atherosclerosis studyE Hoibraaten
Haematological Research Laboratory, Department of Haematology, Oslo, Norway
Thromb Res 98:19-27. 2000..In conclusion, treatment with transdermal estradiol combined with long-cycle progestins was associated with no net activation of coagulation despite reduced levels of coagulation inhibitors...
Association between HIV infection and attenuated diurnal blood pressure rhythm in untreated hypertensive individualsM Baekken
Department of Infectious Diseases, Ullevaal University Hospital, Oslo, Norway
HIV Med 10:44-52. 2009..e. a fall in systolic blood pressure <10% during the night compared with the day), than with casual BP. The aim of the study was to assess the ABP pattern in an HIV-infected cohort in which hypertension was newly diagnosed...
Metformin and antihypertensive therapy with drugs blocking the renin angiotensin system, a cause of concern?H Gudmundsdottir
Department of Nephrology, Ulleval University Hospital, Oslo, Norway
Clin Nephrol 66:380-5. 2006..That combination can become life-threatening under certain circumstances...
Smoking and relation to other risk factors in postmenopausal women with coronary artery disease, with particular reference to whole blood viscosity and beta-cell functionI Os
Department of Pharmacotherapeutics, Postbox 1065, Blindern, University of Oslo, NO 0316 Oslo, Norway
J Intern Med 253:232-9. 2003..To investigate possible associations between smoking habits and other coronary risk factors in postmenopausal women with known coronary heart disease (CHD)...
Tissue Doppler imaging describes diastolic function in men prone to develop hypertension over twenty yearsA Strand
Department of Cardiology, Ullevaal University Hospital, Oslo, Norway
Eur J Echocardiogr 9:34-9. 2008..A method for reliably detecting the onset of LV dysfunction before transition to irreversible damage of the myocardium would be of crucial importance in subjects with essential hypertension...
[Metformin and contrast media--increased risk of lactic acidosis?]N E Kløw
Hjerte og karradiologisk avdeling, Ullevål sykehus 0407 Oslo
Tidsskr Nor Laegeforen 121:1829. 2001..A recent review of the literature has resulted in new recommendations in Europe and the USA. We suggest new guidelines for Norway with regard to the use of metformin in patients undergoing radiological examination with contrast media...
Transforming growth factor (TGF)-beta1 inversely related to vascular cell adhesion molecule-1 in postmenopausal women with coronary artery disease. A possible mechanism for the putative cardioprotective role of TGF-beta1?I Os
Department of Nephrology, Ulleval University Hospital, Oslo, Norway
J Intern Med 251:223-7. 2002..The purpose of the present investigation was to look at a possible relationship between circulating active TGF-beta1 and adhesion molecules in postmenopausal women with angiographically verified coronary heart disease (CHD) (n=118)...
Increased plasma concentrations of TGF-beta1 after hormone replacement therapyS Djurovic
Department of Medical Genetics, Ulleval University Hospital, Osla, Norway
J Intern Med 247:279-85. 2000..The women had angiographically documented coronary heart disease (CHD) and were randomized to either sequential transdermal 17beta-oestradiol for 14 weeks and then medroxyprogesterone (MPA) for 14 days (HRT) or to a control group (C)...
[Prevention of cardiovascular disease in type 2 diabetes]K I Birkeland
Hormonlaboratoriet, Aker sykehus, Oslo
Tidsskr Nor Laegeforen 120:2554-9. 2000..Epidemiological studies show that many of the risk factors are the same as in non-diabetic subjects. At present there are sufficient data in the literature to recommend prophylactic measures to be initiated in diabetic patients...
Varicella infection in a renal transplant recipient associated with abdominal pain, hepatitis, and glomerulonephritisI Os
Department of Nephrology, Ulleval University Hospital, Oslo, Norway
Scand J Urol Nephrol 35:330-3. 2001..The ongoing immunosuppression may have modified the mesangial cell response to the deposition of immune complexes...
Association between albumin:creatinine ratio and 24-hour ambulatory blood pressure in essential hypertensionV A Boulatov
Department of Nephrology, Ulleval University Hospital, Oslo, Norway
Am J Hypertens 14:338-44. 2001..In conclusion, the threshold level of ACR > or = 3.0 mg/mmol currently used to define microalbuminuria may be not applicable to EH. Instead, a threshold level of ACR > or = 1. 5 mg/mmol may be more appropriate...
Effect and tolerability of combining lovastatin with nifedipine or lisinoprilI Os
Department of Nephrology, , Oslo, Norway
Am J Hypertens 6:688-92. 1993..Liver enzymes increased slightly during lovastatin therapy, while no case of myopathy was reported. Combined therapy with lovastatin and antihypertensive therapy can be safely undertaken...
Comparison of doxazosin GITS and standard doxazosin in the treatment of high blood pressureI Os
Department of Nephrology, Ulleval University Hospital, Oslo, Norway
Int J Clin Pharmacol Ther 44:99-106. 2006....
Acute kidney injury with renal replacement therapy in trauma patientsS Beitland
Department of Anaesthesiology, Oslo University Hospital Ullevaal, Oslo, Norway
Acta Anaesthesiol Scand 54:833-40. 2010..Acute kidney injury (AKI) with renal replacement therapy (RRT) is rare in trauma patients. The primary aim of the study was to assess incidence, mortality and chronic RRT dependency in this patient group...
