Research Topics
| Didrik F VestrheimSummaryAffiliation: Norwegian Institute of Public Health Country: Norway Publications
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Detail Information
Publications
Effectiveness of a 2+1 dose schedule pneumococcal conjugate vaccination programme on invasive pneumococcal disease among children in NorwayDidrik F Vestrheim
Division of Infectious Disease Control, Norwegian Institute of Public Health, Nydalen, Oslo, Norway
Vaccine 26:3277-81. 2008..No vaccine failure was seen after complete primary immunization with two vaccine doses. Our findings indicate that PCV-7 provides highly effective protection against vaccine serotype IPD when administered in a 2+1 dose schedule...
Recovery of Bordetella pertussis from PCR-positive nasopharyngeal samples is dependent on bacterial loadDidrik F Vestrheim
Department of Bacteriology and Immunology, Norwegian Institute of Public Health, Oslo, Norway
J Clin Microbiol 50:4114-5. 2012..Growth was associated with a high bacterial load, as determined by PCR. Culture from PCR-positive samples is a feasible approach to recover B. pertussis isolates, and culture can be limited to samples with a high bacterial load...
Postvaccination increase in serotype 19A pneumococcal disease in Norway is driven by expansion of penicillin-susceptible strains of the ST199 complexDidrik F Vestrheim
Department of Bacteriology and Immunology, Norwegian Institute of Public Health, Oslo, Norway
Clin Vaccine Immunol 19:443-5. 2012..Hence, serotype 19A replacement occurs, although it is not driven by antibiotic selection pressure...
Indirect effect of conjugate pneumococcal vaccination in a 2+1 dose scheduleDidrik F Vestrheim
Division of Infectious Disease Control, Norwegian Institute of Public Health, NO 0403Oslo, Norway
Vaccine 28:2214-21. 2010..Among the adults aged > or = 65 years the incidence rate of IPD caused by serotypes not included in PCV7 increased. No vaccine failure was identified, indicating a very high effectiveness of the 2+1 dose schedule vaccination programme...
Pherotypes of pneumococcal strains co-existing in healthy childrenDidrik F Vestrheim
Department of Bacteriology and Immunology, Norwegian Institute of Public Health, Oslo, Norway
Infect Genet Evol 11:1703-8. 2011..3%). The observed distribution of pherotypes in sets of co-colonising pneumococcal strains did not differ from the probability estimate. Thus, co-colonisation of S. pneumoniae in healthy children is not restricted by pherotype...
Impact of a pneumococcal conjugate vaccination program on carriage among children in NorwayDidrik F Vestrheim
Department of Bacteriology and Immunology, Division of Infectious Disease Control, Norwegian Institute of Public Health, Nydalen, Oslo, Norway
Clin Vaccine Immunol 17:325-34. 2010..Direct and indirect protection of PCV7 against nasopharyngeal colonization was inferred from an overall decrease in carriage of PCV7 serotypes. No preference was found for nonsusceptible clones among the replacing non-PCV7 serotypes...
Phenotypic and genotypic characterization of Streptococcus pneumoniae strains colonizing children attending day-care centers in NorwayDidrik F Vestrheim
Department of Bacteriology and Immunology, Division of Infectious Disease Control, Norwegian Institute of Public Health, P O Box 4404 Nydalen, N 0403 Oslo, Norway
J Clin Microbiol 46:2508-18. 2008..Our study indicates that carriage of S. pneumoniae is highly prevalent among children in Norwegian DCCs, with a genetically diverse pneumococcal population consisting of unique microepidemic DCC populations...
Decline in early childhood respiratory tract infections in the Norwegian mother and child cohort study after introduction of pneumococcal conjugate vaccinationMaria C Magnus
Department of Chronic Diseases, Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway
Pediatr Infect Dis J 31:951-5. 2012..A substantial effectiveness of PCV7 immunization against invasive pneumococcal disease has been demonstrated, whereas evidence of its impact on respiratory tract infections are less consistent...
[Bacterial resistance against antibiotics]E Arne Høiby
Avdeling for bakteriologi og infeksjonsimmunologi Nasjonalt folkehelseinstitutt Postboks 4404 Nydalen 0403 Oslo
Tidsskr Nor Laegeforen 128:2452-6. 2008..Antibiotic resistance has progressed over many decades and is increasingly problematic. This paper gives a short summary of antibiotic resistance and its biology...
