Research Topics
| Gudrun HøisethSummaryAffiliation: Norwegian Institute of Public Health Country: Norway Publications
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Detail Information
Publications
Ethyl glucuronide concentrations in oral fluid, blood, and urine after volunteers drank 0.5 and 1.0 g/kg doses of ethanolGudrun Høiseth
Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, Nydalen, Oslo, Norway
J Anal Toxicol 34:319-24. 2010..5 h (range 3.5-11.5 h) in oral fluid. According to this, the detection time for EtG in oral fluid is therefore only a few hours longer than for ethanol itself and represents limited additional value...
Higher levels of hair ethyl glucuronide in patients with decreased kidney functionGudrun Høiseth
Division of Forensic Medicine and Drug Abuse Research, Norwegian Institute of Public Health, Oslo, Norway
Alcohol Clin Exp Res 37:E14-6. 2013..The aim of this study was to compare hair EtG levels in patients with decreased kidney function to those seen in healthy volunteers...- CYP2C19 genetics in fatal carisoprodol intoxicationsGudrun Høiseth
Center for Psychopharmacology, Diakonhjemmet Hospital, Forskningsveien 7, PB 85 Vinderen, 0319, Oslo, Norway
Eur J Clin Pharmacol 68:1561-5. 2012..The objective of this study was to investigate the role of CYP2C19 genetics in mortalities due to carisoprodol intoxication... - Prolonged urinary detection times of EtG and EtS in patients with decreased renal functionGudrun Høiseth
Division of Forensic Toxicology and Drug Abuse, Norwegian Institute of Public Health, Oslo, Norway
Alcohol Clin Exp Res 36:1148-51. 2012.... - Blood kinetics of ethyl glucuronide and ethyl sulphate in heavy drinkers during alcohol detoxificationGudrun Høiseth
Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, Oslo, Norway
Forensic Sci Int 188:52-6. 2009..In the present work, there was one exception to this, and we propose that this could be explained by the patient's renal disease, which would delay excretion of these conjugated metabolites... - Levels of ethyl glucuronide and ethyl sulfate in oral fluid, blood, and urine after use of mouthwash and ingestion of nonalcoholic wineGudrun Høiseth
Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, Oslo, Norway
J Anal Toxicol 34:84-8. 2010..Finally, the study showed that a positive EtG or EtS result after accidental alcohol exposure is unlikely in blood and oral fluid... - Practical use of ethyl glucuronide and ethyl sulfate in postmortem cases as markers of antemortem alcohol ingestionGudrun Høiseth
Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, Pb 4404 Nydalen, Oslo, Norway
Int J Legal Med 124:143-8. 2010..In the last case, the interpretation was more difficult. One possible explanation would be postmortem degradation of EtG in blood... - The effect of scheduling and withdrawal of carisoprodol on prevalence of intoxications with the drugGudrun Høiseth
Division of Forensic Toxicology and Drug Abuse, Norwegian Institute of Public Health, P O Box 4404 Nydalen, NO 0403 Oslo, Norway
Basic Clin Pharmacol Toxicol 105:345-9. 2009..This, together with previous publications, indicates that the population reflected in our data uses regularly prescribed carisoprodol and, to a lesser degree, drug from an illegal street market... - Serum/whole blood concentration ratio for ethylglucuronide and ethyl sulfateGudrun Høiseth
Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, Nydalen, Oslo, Norway
J Anal Toxicol 33:208-11. 2009..001). The higher concentrations of EtG and EtS in serum than in whole blood have to be considered when whole blood results obtained from forensic toxicology are compared to serum or plasma results from clinical laboratories... - Ethyl glucuronide in hair compared with traditional alcohol biomarkers--a pilot study of heavy drinkers referred to an alcohol detoxification unitGudrun Høiseth
Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, Oslo, Norway
Alcohol Clin Exp Res 33:812-6. 2009..We also wanted to study the quantitative relation between alcohol intake and the different biomarkers... - Comparison between the urinary alcohol markers EtG, EtS, and GTOL/5-HIAA in a controlled drinking experimentGudrun Høiseth
Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, Pb 4404 Nydalen, N 0403 Oslo, Norway
Alcohol Alcohol 43:187-91. 2008..The aim of this controlled study was to compare the sensitivities and detection times of EtG, EtS, and GTOL/5-HIAA, after a single ingestion of ethanol... - In vitro formation of ethanol in autopsy samples containing fluoride ionsGudrun Høiseth
Division of Forensic Toxicology and Drug Abuse, Norwegian Institute of Public Health, Pb 4404 Nydalen, 0403, Oslo, Norway
Int J Legal Med 122:63-6. 2008..Possible reasons for this unusual formation of ethanol were the abundant presence of bacteria, a high level of glucose and, possibly, an insufficient amount of fluoride added to the vials... - Disappearance of ethyl glucuronide during heavy putrefactionGudrun Høiseth
Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, Pb 4404 Nydalen, N 0403 Oslo, Norway
Forensic Sci Int 176:147-51. 2008..Further, we used the information from the in vitro study on real cases, to get an impression of the practical problem of degradation or formation of EtG... - A pharmacokinetic study of ethyl glucuronide in blood and urine: applications to forensic toxicologyGudrun Høiseth
Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, Nydalen, Oslo, Norway
Forensic Sci Int 172:119-24. 2007..For this purpose, two subsequent increasing EtG values and a high ethanol-to-EtG ratio in blood would support information of recent drinking... - Carisoprodol intoxications: a retrospective study of forensic autopsy material from 1992-2003Gudrun Høiseth
Division of Forensic Toxicology and Drug Abuse, Norwegian Institute of Public Health, P O Box 4404, Nydalen, 0403 Oslo, Norway
Int J Legal Med 121:403-9. 2007..There were, however, only a small number of cases where the cause of death can be attributed to use of carisoprodol alone... - Divergent associations of drinking frequency and binge consumption of alcohol with mortality within the same cohortSidsel Graff-Iversen
Department of Chronic Diseases, Norwegian Institute of Public Health, Oslo, Norway
J Epidemiol Community Health 67:350-7. 2013..The aim of this study was to assess the associations of alcohol use with mortality in a population with a hybrid of drinking patterns... - A study of ethyl glucuronide in post-mortem blood as a marker of ante-mortem ingestion of alcoholGudrun Høiseth
Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, Pb 4404 Nydalen, N 0403 Oslo, Norway
Forensic Sci Int 165:41-5. 2007..In conclusion, blood EtG determination seems to be a reliable marker of ante-mortem ingestion of alcohol, and it could be considered in forensic autopsy cases when post-mortem formation of ethanol is questioned... - Acute intoxications with carisoprodolGudrun Høiseth
Division of Forensic Toxicology and Drug Abuse, Norwegian Institute of Public Health, Oslo, Norway
Clin Toxicol (Phila) 46:307-9. 2008..Despite the potential weaknesses of the present material, this study gave an additional indication of a high toxicity of carisoprodol... - Is ADH1C genotype relevant for the cardioprotective effect of alcohol?Gudrun Høiseth
Division of Forensic Medicine and Drug Abuse Research, Norwegian Institute of Public Health, Oslo, Norway
Alcohol 47:81-4. 2013..This study, which included the largest study group published so far, failed to find any link between the ADH1C genotype and the cardioprotective effects of alcohol... - [Psychiatric and cognitive long-term effects of ecstasy]Gudrun Høiseth
Divisjon for rettstoksikologi og rusmiddelforskning, Nasjonalt folkehelseinstitutt, Postboks 4404 Nydalen, 0403 Oslo
Tidsskr Nor Laegeforen 126:596-8. 2006..We wanted to review human studies to find evidence for these side effects of ecstasy... - [Phencyclidine--angel dust]Gudrun Høiseth
Divisjon for rettstoksikologi og rusmiddelforskning, Nasjonalt folkehelseinstitutt, Postboks 4404 Nydalen, 0403 Oslo
Tidsskr Nor Laegeforen 125:2775-6. 2005..For the first time in ten years, phencyclidine (PCP) has been confiscated in Norway. Physicians should be aware of this substance when treating intoxications... - [Ricin--a therapeutic agent and a biological weapon]Gudrun Høiseth
Divisjon for rettstoksikologi og rusmiddelforskning, Nasjonalt folkehelseinstitutt, Postboks 4404 Nydalen, 0403 Oslo
Tidsskr Nor Laegeforen 125:2477-9. 2005..Ricin is a highly toxic plant protein that is lethal in small doses; it kills cells by inactivating ribosomes but has potential for medical use... - Controlling for high-density lipoprotein cholesterol does not affect the magnitude of the relationship between alcohol and coronary heart diseasePer Magnus
Norwegian Institute of Public Health, Nydalen, Oslo, Norway
Circulation 124:2296-302. 2011..This study tested the hypothesis that moderate alcohol intake exerts its cardioprotective effect mainly through an increase in the serum level of high-density lipoprotein cholesterol... - Heroin-using drivers: importance of morphine and morphine-6-glucuronide on late clinical impairmentLiliana Bachs
Division for Forensic Toxicology and Drug Abuse, Norwegian Institute of Public Health, P O Box 4404, Nydalen, 0403, Oslo, Norway
Eur J Clin Pharmacol 62:905-12. 2006..To evaluate the relationship between major heroin metabolites (morphine, morphine-6-glucoronide), pattern of drug use, and late impairment of psychomotor functions...