Research Topics
| Atle FretheimSummaryAffiliation: Norwegian Knowledge Centre for the Health Services Country: Norway Publications
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Detail Information
Publications
SUPPORT Tools for evidence-informed health Policymaking (STP) 13: Preparing and using policy briefs to support evidence-informed policymakingJohn N Lavis
Centre for Health Economics and Policy Analysis, Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St West, HSC 2D3, Hamilton, ON, Canada, L8N 3Z5
Health Res Policy Syst 7:S13. 2009..Does the policy brief employ a graded-entry format? 6. Was the policy brief reviewed for both scientific quality and system relevance?..
SUPPORT Tools for evidence-informed health Policymaking (STP)John N Lavis
Centre for Health Economics and Policy Analysis, Department of Clinical Epidemiology and Biostatistics, and Department of Political Science, McMaster University, 1200 Main St, West, HSC 2D3, Hamilton, ON, Canada, L8N 3Z5
Health Res Policy Syst 7:I1. 2009..Additional information resources are listed and described in every article. The evaluation of ways to support evidence-informed health policymaking is a developing field and feedback about how to improve the series is welcome...
SUPPORT Tools for evidence-informed health Policymaking (STP) 14: Organising and using policy dialogues to support evidence-informed policymakingJohn N Lavis
Centre for Health Economics and Policy Analysis, Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St West, HSC 2D3, Hamilton, ON, Canada, L8N 3Z5
Health Res Policy Syst 7:S14. 2009..Does the dialogue engage a facilitator, follow a rule about not attributing comments to individuals, and not aim for consensus? 6. Are outputs produced and follow-up activities undertaken to support action?..
SUPPORT Tools for evidence-informed health Policymaking (STP) 7: Finding systematic reviewsJohn N Lavis
Centre for Health Economics and Policy Analysis, Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St West, HSC 2D3, Hamilton, ON, Canada, L8N 3Z5
Health Res Policy Syst 7:S7. 2009..These are: 1. Is a systematic review really what is needed? 2. What databases and search strategies can be used to find relevant systematic reviews? 3. What alternatives are available when no relevant review can be found?..
SUPPORT Tools for evidence-informed health Policymaking (STP) 5: Using research evidence to frame options to address a problemJohn N Lavis
Centre for Health Economics and Policy Analysis, Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St West, HSC 2D3, Hamilton, ON, Canada L8N 3Z5
Health Res Policy Syst 7:S5. 2009..What adaptations might be made to any given option and could they alter its benefits, harms and costs? 6. Which stakeholder views and experiences might influence an option's acceptability and its benefits, harms, and costs?..
SUPPORT Tools for evidence-informed health Policymaking (STP) 9: Assessing the applicability of the findings of a systematic reviewJohn N Lavis
Centre for Health Economics and Policy Analysis, Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St West, HSC 2D3, Hamilton, ON, Canada, L8N 3Z5
Health Res Policy Syst 7:S9. 2009....
SUPPORT Tools for evidence-informed health Policymaking (STP) 4: Using research evidence to clarify a problemJohn N Lavis
Centre for Health Economics and Policy Analysis, Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St West, HSC 2D3, Hamilton, ON, Canada, L8N 3Z5
Health Res Policy Syst 7:S4. 2009..What comparisons can be made to establish the magnitude of the problem and to measure progress in addressing it? 5. How can the problem be framed (or described) in a way that will motivate different groups?..
SUPPORT Tools for evidence-informed health Policymaking (STP) 3: Setting priorities for supporting evidence-informed policymakingJohn N Lavis
Centre for Health Economics and Policy Analysis, Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main St West, HSC 2D3, Hamilton, ON, Canada, L8N 3Z5
Health Res Policy Syst 7:S3. 2009..Does the approach incorporate an explicit process for determining priorities? 4. Does the approach incorporate a communications strategy and a monitoring and evaluation plan?..
Comparative effectiveness of antihypertensive medication for primary prevention of cardiovascular disease: systematic review and multiple treatments meta-analysisAtle Fretheim
Global Health Unit, Norwegian Knowledge Centre for the Health Services, Oslo, Norway
BMC Med 10:33. 2012..to answer the following research question: What are the relative effects of different classes of antihypertensive drugs in reducing the incidence of cardiovascular disease outcomes for healthy people at risk of cardiovascular disease?..
SUPPORT tools for evidence-informed policymaking in health 6: Using research evidence to address how an option will be implementedAtle Fretheim
Norwegian Knowledge Centre for the Health Services, P O Box 7004, St Olavs Plass, N 0130 Oslo, Norway
Health Res Policy Syst 7:S6. 2009..What strategies should be considered in planning the implementation of a new policy in order to facilitate the necessary systems changes?..
Rational prescribing in primary care (RaPP): a cluster randomized trial of a tailored interventionAtle Fretheim
Norwegian Knowledge Centre for Health Services, Oslo, Norway
PLoS Med 3:e134. 2006..We evaluated the effects of a tailored intervention to support the implementation of systematically developed guidelines for the use of antihypertensive and cholesterol-lowering drugs for the primary prevention of cardiovascular disease...
Rational prescribing in primary care (RaPP): economic evaluation of an intervention to improve professional practiceAtle Fretheim
Norwegian Knowledge Centre for Health Services, Oslo, Norway
PLoS Med 3:e216. 2006..The increased use of thiazides was not expected to have an impact on health outcomes...
The effects of mandatory prescribing of thiazides for newly treated, uncomplicated hypertension: interrupted time-series analysisAtle Fretheim
Norwegian Knowledge Centre for the Health Services, Oslo, Norway
PLoS Med 4:e232. 2007..The objective of the new regulation was to reduce drug expenditures...
SUPPORT tools for evidence-informed policymaking in health 18: Planning monitoring and evaluation of policiesAtle Fretheim
Norwegian Knowledge Centre for the Health Services, P O Box 7004, St Olavs Plass, N 0130 Oslo, Norway
Health Res Policy Syst 7:S18. 2009..These are: 1. Is monitoring necessary? 2. What should be measured? 3. Should an impact evaluation be conducted? 4. How should the impact evaluation be done?..
The effect of how outcomes are framed on decisions about whether to take antihypertensive medication: a randomized trialCheryl L L Carling
Norwegian Knowledge Centre for the Health Services, Oslo, Norway
PLoS ONE 5:e9469. 2010....
Improving prescribing of antihypertensive and cholesterol-lowering drugs: a method for identifying and addressing barriers to changeAtle Fretheim
Informed Choice Research Department, Norwegian Health Services Research Centre, P, O, Box 7004, St, Olavs plass, Oslo, Norway
BMC Health Serv Res 4:23. 2004..We also report the results of a post hoc exercise and survey we carried out to evaluate our approach for identifying barriers and tailoring interventions...
Choice of generic antihypertensive drugs for the primary prevention of cardiovascular disease--a cost-effectiveness analysisTorbjørn Wisløff
Institute of Health and Society, University of Oslo, Oslo, Norway
BMC Cardiovasc Disord 12:26. 2012..The objective of this study was to explore the cost-effectiveness of different generic antihypertensive drugs as first, second and third choice for primary prevention of cardiovascular disease...
A televised, web-based randomised trial of an herbal remedy (valerian) for insomniaAndrew D Oxman
Norwegian Knowledge Centre for the Health Services, Oslo, Norway
PLoS ONE 2:e1040. 2007..Valerian is an herbal over-the-counter drug that is widely used for insomnia. Systematic reviews have found inconsistent and inconclusive results about its effects...
International variation in prescribing antihypertensive drugs: its extent and possible explanationsAtle Fretheim
Informed Choice Research Department, Norwegian Health Services Research Centre, P O Box 7004, St Olavs Plass, Oslo, Norway
BMC Health Serv Res 5:21. 2005..We wanted to describe prescribing patterns of antihypertensive drugs in ten countries and explore possible reasons for inter-country variation...
SUPPORT tools for evidence-informed policymaking in health 11: Finding and using evidence about local conditionsSimon Lewin
Norwegian Knowledge Centre for the Health Services, P O Box 7004, St Olavs Plass, N 0130 Oslo, Norway
Health Res Policy Syst 7:S11. 2009..How should the quality of the available local evidence be assessed? 4. Are there important variations in the availability, quality or results of local evidence? 5. How should local evidence be incorporated with other information?..
The effect of alternative graphical displays used to present the benefits of antibiotics for sore throat on decisions about whether to seek treatment: a randomized trialCheryl L L Carling
Norwegian Knowledge Centre for the Health Services, Oslo, Norway
PLoS Med 6:e1000140. 2009..Our objective was to determine which display resulted in choices most consistent with participants' values...
SUPPORT Tools for evidence-informed health Policymaking (STP) 2: Improving how your organisation supports the use of research evidence to inform policymakingAndrew D Oxman
Norwegian Knowledge Centre for the Health Services, P O Box 7004, St Olavs Plass, N 0130 Oslo, Norway
Health Res Policy Syst 7:S2. 2009..What strategies should be used to ensure the use of systematic and transparent methods for accessing, appraising and using research evidence? 5. What strategies should be used to ensure adequate capacity to employ these methods?..
SUPPORT Tools for evidence-informed health Policymaking (STP) 17: Dealing with insufficient research evidenceAndrew D Oxman
Norwegian Knowledge Centre for the Health Services, P O Box 7004, St Olavs Plass, N 0130 Oslo, Norway
Health Res Policy Syst 7:S17. 2009..Has inconclusive evidence been misinterpreted as evidence of no effect? 3. Is it possible to be confident about a decision despite a lack of evidence? 4. Is the option potentially harmful, ineffective or not worth the cost?..
SUPPORT Tools for evidence-informed health Policymaking (STP) 15: Engaging the public in evidence-informed policymakingAndrew D Oxman
Norwegian Knowledge Centre for the Health Services, P O Box 7004, St Olavs Plass, N 0130 Oslo, Norway
Health Res Policy Syst 7:S15. 2009..What strategies can be used when working with civil society groups to inform and engage them in policy development and implementation? 3. What methods can be used to involve consumers in policy development and implementation?..
SUPPORT Tools for evidence-informed health Policymaking (STP) 12: Finding and using research evidence about resource use and costsAndrew D Oxman
Norwegian Knowledge Centre for the Health Services, P O Box 7004, St Olavs Plass, N 0130 Oslo, Norway
Health Res Policy Syst 7:S12. 2009..What evidence is there for important impacts on resource use? 3. How confident is it possible to be in the evidence for impacts on resource use? 4. Have the impacts on resource use been valued appropriately in terms of their true costs?..
SUPPORT Tools for evidence-informed health Policymaking (STP) 10: Taking equity into consideration when assessing the findings of a systematic reviewAndrew D Oxman
Norwegian Knowledge Centre for the Health Services, P O Box 7004, St Olavs Plass, N 0130 Oslo, Norway
Health Res Policy Syst 7:S10. 2009..Are there important considerations that should be made when implementing the option in order to ensure that inequities are reduced, if possible, and that they are not increased?..
SUPPORT Tools for evidence-informed health Policymaking (STP) 1: What is evidence-informed policymaking?Andrew D Oxman
Norwegian Knowledge Centre for the Health Services, P O Box 7004, St Olavs Plass, N 0130 Oslo, Norway
Health Res Policy Syst 7:S1. 2009..Evidence-informed policymaking helps policymakers gain an understanding of these processes...
SUPPORT Tools for evidence-informed health Policymaking (STP) 8: Deciding how much confidence to place in a systematic reviewSimon Lewin
Norwegian Knowledge Centre for the Health Services, P O Box 7004, St Olavs Plass, N 0130 Oslo, Norway
Health Res Policy Syst 7:S8. 2009..Was the search for relevant studies detailed and reasonably comprehensive? 4. Were assessments of the studies' relevance to the review topic and of their risk of bias reproducible? 5. Were the results similar from study to study?..
SUPPORT Tools for evidence-informed health Policymaking (STP) 16: Using research evidence in balancing the pros and cons of policiesAndrew D Oxman
Norwegian Knowledge Centre for the Health Services, P O Box 7004, St Olavs Plass, N 0130 Oslo, Norway
Health Res Policy Syst 7:S16. 2009..How confident can policymakers and others be in the estimated impacts? 5. Is a formal economic model likely to facilitate decision making?..
Use of evidence in WHO recommendationsAndrew D Oxman
Norwegian Knowledge Centre for the Health Services, PO Box 7004, St Olavs Plass, N 0130 Oslo, Norway
Lancet 369:1883-9. 2007..We examined the use of evidence, particularly evidence of effects, in recommendations developed by WHO departments...
The OFF theory of research utilizationAndrew D Oxman
Norwegian Health Services Research Centre, Informed Choice Research Department, PO Box 7004, St. Olavs plass, Oslo, Norway
J Clin Epidemiol 58:113-6; discussion 117-20. 2005
Paying for performance to improve the delivery of health interventions in low- and middle-income countries Sophie Witter
Immpact, University of Aberdeen, Aberdeen, UK 2Global Health Unit, Norwegian Knowledge Centre for the Health Services, Oslo, Norway
Cochrane Database Syst Rev 2:CD007899. 2012..A review of evidence on effectiveness is therefore timely, especially as this is an area of growing interest for funders and governments...
Can paying for results help to achieve the Millennium Development Goals? Overview of the effectiveness of results-based financingAndrew D Oxman
Norwegian Knowledge Centre for the Health Services, Oslo, Norway
J Evid Based Med 2:70-83. 2009..Results-based financing is widely advocated for achieving health goals, including the Millennium Development Goals...
Can paying for results help to achieve the Millennium Development Goals? A critical review of selected evaluations of results-based financingAndrew D Oxman
Norwegian Knowledge Centre for the Health Services, Oslo, Norway
J Evid Based Med 2:184-95. 2009..RBF is being promoted for helping to achieve the Millennium Development Goals (MDGs)...
[Do the fee-for-service and reimbursement influence medical practice?]Atle Fretheim
Avdeling for helsetjenesteforskning Sosial og helsedirektoratet Postboks 8054 Dep 0031 Oslo
Tidsskr Nor Laegeforen 123:795-6. 2003
[Which antihypertensive drugs should be used in the primary prevention of cardiovascular disease?]Atle Fretheim
Brannstasjonen legesenter Arendalsvei 26a 4898 Grimstad
Tidsskr Nor Laegeforen 122:2283-6. 2002..We have used systematic and explicit methods in the development of a new set of recommendations. This is the second of three articles describing these guidelines...
Rational Prescribing in Primary Care (RaPP-trial). A randomised trial of a tailored intervention to improve prescribing of antihypertensive and cholesterol-lowering drugs in general practice [ISRCTN48751230]Atle Fretheim
Department of Health Services Research, Norwegian Directorate for Health and Social Affairs, N 0031 Oslo, Norway
BMC Health Serv Res 3:5. 2003....
The relation between methods and recommendations in clinical practice guidelines for hypertension and hyperlipidemiaAtle Fretheim
Department of Health Services Research, Norwegian Directorate for Health Social Welfare, PO Box 8054 Dep, N 0031 Oslo, Norway
J Fam Pract 51:963-8. 2002..To assess the association between methods used to develop clinical practice guidelines and the recommendations that are made...
[Which cholesterol-lowering drugs should be used in the primary prevention of cardiovascular disease?]Atle Fretheim
Brannstasjonen legesenter Arendalsvei 26a 4898 Grimstad
Tidsskr Nor Laegeforen 122:2287-8. 2002..We have used systematic and explicit methods in developing a new set of recommendations. This is the last of three articles describing these guidelines...
The potential savings of using thiazides as the first choice antihypertensive drug: cost-minimisation analysisAtle Fretheim
Department of Health Services Research, Norwegian Directorate for Health and Social Affairs, N 0031 Oslo, Norway
BMC Health Serv Res 3:18. 2003..Despite this, the use of thiazides is much lower than that of other drug-classes. We wanted to estimate the potential for savings if thiazides were used as the first choice drug for the management of uncomplicated hypertension...
VALUE: analysis of resultsAtle Fretheim
Lancet 364:934-5; author reply 935. 2004
Back to thiazide-diuretics for hypertension: reflections after a decade of irrational prescribingAtle Fretheim
Department of Health Services Research, Norwegian Directorate for Health and Social Affairs, N 0031 Oslo, Norway
BMC Fam Pract 4:19. 2003....
[Guidelines for pharmacological primary prevention of cardiovascular diseases--who should be treated?]Atle Fretheim
Brannstasjonen legesenter Arendalsvei 26a 4898 Grimstad
Tidsskr Nor Laegeforen 122:2277-81. 2002..We have used systematic and explicit methods in the development of a new set of recommendations. This is the first of three articles describing these guidelines...
[Guidelines in general practice--are they read and are they used?]Shaun Treweek
Avdeling for informerte helsebeslutninger, Nasjonalt kunnskapssenter for helsetjenesten, Postboks 7004 St Olavs plass, 0130 Oslo
Tidsskr Nor Laegeforen 125:300-3. 2005..Many guidelines are not developed from systematic models and are not based on high-quality evidence. The existence of a guideline does not in itself lead to changes in practice and many guidelines are not used once they have been issued...
[What do general practitioners do to keep themselves up to date?]Shaun Treweek
Avdeling for informerte helsebeslutninger, Nasjonalt kunnskapssenter for helsetjenesten, Postboks 7004 St Olavs plass, 0130 Oslo
Tidsskr Nor Laegeforen 125:304-6. 2005..Continuing education should ensure that a doctor provides effective care based on the best available evidence. But not all continuing education is equally effective...
[Misleading about thiazides]Atle Fretheim
Tidsskr Nor Laegeforen 124:3259-60; author reply 3260. 2004
[Research interpretation]Atle Fretheim
Avdeling for informerte helsebeslutninger, Nasjonalt kunnskapssenter for helsetjenesten, Oslo
Tidsskr Nor Laegeforen 124:2656-8. 2004
[Shortcomings and strength of practice guidelines]Atle Fretheim
Tidsskr Nor Laegeforen 123:1566-7. 2003
[Thiazides--good first choice preparations in hypertension]Atle Fretheim
Avdeling for helsetjenesteforskning Sosial og helsedirektoratet Postboks 8054 Dep 0031 Oslo
Tidsskr Nor Laegeforen 123:1236. 2003
[Thiazides (only) and hard endpoints]Signe Flottorp
Tidsskr Nor Laegeforen 124:2277; author reply 2277-8. 2004
[Thiazides in the treatment of hypertension]Atle Fretheim
Tidsskr Nor Laegeforen 123:2621. 2003
[How do general practice assistants keep themselves up to date?]Kari Håvelsrud
Avdeling for informerte helsebeslutninger, Nasjonalt kunnskapssenter for helsetjenesten, Postboks 7004 St Olavs plass 0130 Oslo
Tidsskr Nor Laegeforen 125:307-9. 2005....
