Atle Fretheim

Summary

Affiliation: Norwegian Health Services Research Centre
Country: Norway

Publications

  1. pmc Improving prescribing of antihypertensive and cholesterol-lowering drugs: a method for identifying and addressing barriers to change
    Atle Fretheim
    Informed Choice Research Department, Norwegian Health Services Research Centre, P, O, Box 7004, St, Olavs plass, Oslo, Norway
    BMC Health Serv Res 4:23. 2004
  2. pmc International variation in prescribing antihypertensive drugs: its extent and possible explanations
    Atle Fretheim
    Informed Choice Research Department, Norwegian Health Services Research Centre, P O Box 7004, St Olavs Plass, Oslo, Norway
    BMC Health Serv Res 5:21. 2005
  3. pmc The effect of how outcomes are framed on decisions about whether to take antihypertensive medication: a randomized trial
    Cheryl L L Carling
    Norwegian Knowledge Centre for the Health Services, Oslo, Norway
    PLoS ONE 5:e9469. 2010
  4. pmc Rational prescribing in primary care (RaPP): a cluster randomized trial of a tailored intervention
    Atle Fretheim
    Norwegian Knowledge Centre for Health Services, Oslo, Norway
    PLoS Med 3:e134. 2006
  5. pmc Rational prescribing in primary care (RaPP): economic evaluation of an intervention to improve professional practice
    Atle Fretheim
    Norwegian Knowledge Centre for Health Services, Oslo, Norway
    PLoS Med 3:e216. 2006
  6. pmc The effects of mandatory prescribing of thiazides for newly treated, uncomplicated hypertension: interrupted time-series analysis
    Atle Fretheim
    Norwegian Knowledge Centre for the Health Services, Oslo, Norway
    PLoS Med 4:e232. 2007
  7. pmc Comparative effectiveness of antihypertensive medication for primary prevention of cardiovascular disease: systematic review and multiple treatments meta-analysis
    Atle Fretheim
    Global Health Unit, Norwegian Knowledge Centre for the Health Services, Oslo, Norway
    BMC Med 10:33. 2012
  8. pmc Choice of generic antihypertensive drugs for the primary prevention of cardiovascular disease--a cost-effectiveness analysis
    Torbjørn Wisløff
    Institute of Health and Society, University of Oslo, Oslo, Norway
    BMC Cardiovasc Disord 12:26. 2012
  9. pmc The effect of alternative graphical displays used to present the benefits of antibiotics for sore throat on decisions about whether to seek treatment: a randomized trial
    Cheryl L L Carling
    Norwegian Knowledge Centre for the Health Services, Oslo, Norway
    PLoS Med 6:e1000140. 2009
  10. pmc A televised, web-based randomised trial of an herbal remedy (valerian) for insomnia
    Andrew D Oxman
    Norwegian Knowledge Centre for the Health Services, Oslo, Norway
    PLoS ONE 2:e1040. 2007

Detail Information

Publications46

  1. pmc Improving prescribing of antihypertensive and cholesterol-lowering drugs: a method for identifying and addressing barriers to change
    Atle Fretheim
    Informed Choice Research Department, Norwegian Health Services Research Centre, P, O, Box 7004, St, Olavs plass, Oslo, Norway
    BMC Health Serv Res 4:23. 2004
    ..We also report the results of a post hoc exercise and survey we carried out to evaluate our approach for identifying barriers and tailoring interventions...
  2. pmc International variation in prescribing antihypertensive drugs: its extent and possible explanations
    Atle Fretheim
    Informed Choice Research Department, Norwegian Health Services Research Centre, P O Box 7004, St Olavs Plass, Oslo, Norway
    BMC Health Serv Res 5:21. 2005
    ..We wanted to describe prescribing patterns of antihypertensive drugs in ten countries and explore possible reasons for inter-country variation...
  3. pmc The effect of how outcomes are framed on decisions about whether to take antihypertensive medication: a randomized trial
    Cheryl L L Carling
    Norwegian Knowledge Centre for the Health Services, Oslo, Norway
    PLoS ONE 5:e9469. 2010
    ....
  4. pmc Rational prescribing in primary care (RaPP): a cluster randomized trial of a tailored intervention
    Atle Fretheim
    Norwegian Knowledge Centre for Health Services, Oslo, Norway
    PLoS Med 3:e134. 2006
    ..We evaluated the effects of a tailored intervention to support the implementation of systematically developed guidelines for the use of antihypertensive and cholesterol-lowering drugs for the primary prevention of cardiovascular disease...
  5. pmc Rational prescribing in primary care (RaPP): economic evaluation of an intervention to improve professional practice
    Atle Fretheim
    Norwegian Knowledge Centre for Health Services, Oslo, Norway
    PLoS Med 3:e216. 2006
    ..The increased use of thiazides was not expected to have an impact on health outcomes...
  6. pmc The effects of mandatory prescribing of thiazides for newly treated, uncomplicated hypertension: interrupted time-series analysis
    Atle Fretheim
    Norwegian Knowledge Centre for the Health Services, Oslo, Norway
    PLoS Med 4:e232. 2007
    ..The objective of the new regulation was to reduce drug expenditures...
  7. pmc Comparative effectiveness of antihypertensive medication for primary prevention of cardiovascular disease: systematic review and multiple treatments meta-analysis
    Atle Fretheim
    Global Health Unit, Norwegian Knowledge Centre for the Health Services, Oslo, Norway
    BMC Med 10:33. 2012
    ..to answer the following research question: What are the relative effects of different classes of antihypertensive drugs in reducing the incidence of cardiovascular disease outcomes for healthy people at risk of cardiovascular disease?..
  8. pmc Choice of generic antihypertensive drugs for the primary prevention of cardiovascular disease--a cost-effectiveness analysis
    Torbjørn Wisløff
    Institute of Health and Society, University of Oslo, Oslo, Norway
    BMC Cardiovasc Disord 12:26. 2012
    ..The objective of this study was to explore the cost-effectiveness of different generic antihypertensive drugs as first, second and third choice for primary prevention of cardiovascular disease...
  9. pmc The effect of alternative graphical displays used to present the benefits of antibiotics for sore throat on decisions about whether to seek treatment: a randomized trial
    Cheryl L L Carling
    Norwegian Knowledge Centre for the Health Services, Oslo, Norway
    PLoS Med 6:e1000140. 2009
    ..Our objective was to determine which display resulted in choices most consistent with participants' values...
  10. pmc A televised, web-based randomised trial of an herbal remedy (valerian) for insomnia
    Andrew D Oxman
    Norwegian Knowledge Centre for the Health Services, Oslo, Norway
    PLoS ONE 2:e1040. 2007
    ..Valerian is an herbal over-the-counter drug that is widely used for insomnia. Systematic reviews have found inconsistent and inconclusive results about its effects...
  11. pmc SUPPORT tools for evidence-informed policymaking in health 6: Using research evidence to address how an option will be implemented
    Atle Fretheim
    Norwegian Knowledge Centre for the Health Services, P O Box 7004, St Olavs Plass, N 0130 Oslo, Norway
    Health Res Policy Syst 7:S6. 2009
    ..What strategies should be considered in planning the implementation of a new policy in order to facilitate the necessary systems changes?..
  12. pmc SUPPORT Tools for evidence-informed health Policymaking (STP) 17: Dealing with insufficient research evidence
    Andrew D Oxman
    Norwegian Knowledge Centre for the Health Services, P O Box 7004, St Olavs Plass, N 0130 Oslo, Norway
    Health Res Policy Syst 7:S17. 2009
    ..Has inconclusive evidence been misinterpreted as evidence of no effect? 3. Is it possible to be confident about a decision despite a lack of evidence? 4. Is the option potentially harmful, ineffective or not worth the cost?..
  13. pmc SUPPORT Tools for evidence-informed health Policymaking (STP) 1: What is evidence-informed policymaking?
    Andrew D Oxman
    Norwegian Knowledge Centre for the Health Services, P O Box 7004, St Olavs Plass, N 0130 Oslo, Norway
    Health Res Policy Syst 7:S1. 2009
    ..Evidence-informed policymaking helps policymakers gain an understanding of these processes...
  14. pmc SUPPORT Tools for evidence-informed health Policymaking (STP) 10: Taking equity into consideration when assessing the findings of a systematic review
    Andrew D Oxman
    Norwegian Knowledge Centre for the Health Services, P O Box 7004, St Olavs Plass, N 0130 Oslo, Norway
    Health Res Policy Syst 7:S10. 2009
    ..Are there important considerations that should be made when implementing the option in order to ensure that inequities are reduced, if possible, and that they are not increased?..
  15. pmc SUPPORT tools for evidence-informed policymaking in health 11: Finding and using evidence about local conditions
    Simon Lewin
    Norwegian Knowledge Centre for the Health Services, P O Box 7004, St Olavs Plass, N 0130 Oslo, Norway
    Health Res Policy Syst 7:S11. 2009
    ..How should the quality of the available local evidence be assessed? 4. Are there important variations in the availability, quality or results of local evidence? 5. How should local evidence be incorporated with other information?..
  16. pmc SUPPORT Tools for evidence-informed health Policymaking (STP) 8: Deciding how much confidence to place in a systematic review
    Simon Lewin
    Norwegian Knowledge Centre for the Health Services, P O Box 7004, St Olavs Plass, N 0130 Oslo, Norway
    Health Res Policy Syst 7:S8. 2009
    ..Was the search for relevant studies detailed and reasonably comprehensive? 4. Were assessments of the studies' relevance to the review topic and of their risk of bias reproducible? 5. Were the results similar from study to study?..
  17. pmc SUPPORT Tools for evidence-informed health Policymaking (STP) 2: Improving how your organisation supports the use of research evidence to inform policymaking
    Andrew D Oxman
    Norwegian Knowledge Centre for the Health Services, P O Box 7004, St Olavs Plass, N 0130 Oslo, Norway
    Health Res Policy Syst 7:S2. 2009
    ..What strategies should be used to ensure the use of systematic and transparent methods for accessing, appraising and using research evidence? 5. What strategies should be used to ensure adequate capacity to employ these methods?..
  18. pmc SUPPORT tools for evidence-informed policymaking in health 18: Planning monitoring and evaluation of policies
    Atle Fretheim
    Norwegian Knowledge Centre for the Health Services, P O Box 7004, St Olavs Plass, N 0130 Oslo, Norway
    Health Res Policy Syst 7:S18. 2009
    ..These are: 1. Is monitoring necessary? 2. What should be measured? 3. Should an impact evaluation be conducted? 4. How should the impact evaluation be done?..
  19. pmc SUPPORT Tools for evidence-informed health Policymaking (STP) 12: Finding and using research evidence about resource use and costs
    Andrew D Oxman
    Norwegian Knowledge Centre for the Health Services, P O Box 7004, St Olavs Plass, N 0130 Oslo, Norway
    Health Res Policy Syst 7:S12. 2009
    ..What evidence is there for important impacts on resource use? 3. How confident is it possible to be in the evidence for impacts on resource use? 4. Have the impacts on resource use been valued appropriately in terms of their true costs?..
  20. pmc SUPPORT Tools for evidence-informed health Policymaking (STP) 15: Engaging the public in evidence-informed policymaking
    Andrew D Oxman
    Norwegian Knowledge Centre for the Health Services, P O Box 7004, St Olavs Plass, N 0130 Oslo, Norway
    Health Res Policy Syst 7:S15. 2009
    ..What strategies can be used when working with civil society groups to inform and engage them in policy development and implementation? 3. What methods can be used to involve consumers in policy development and implementation?..
  21. pmc SUPPORT Tools for evidence-informed health Policymaking (STP) 16: Using research evidence in balancing the pros and cons of policies
    Andrew D Oxman
    Norwegian Knowledge Centre for the Health Services, P O Box 7004, St Olavs Plass, N 0130 Oslo, Norway
    Health Res Policy Syst 7:S16. 2009
    ..How confident can policymakers and others be in the estimated impacts? 5. Is a formal economic model likely to facilitate decision making?..
  22. doi Paying for performance to improve the delivery of health interventions in low- and middle-income countries 
    Sophie Witter
    Immpact, University of Aberdeen, Aberdeen, UK 2Global Health Unit, Norwegian Knowledge Centre for the Health Services, Oslo, Norway
    Cochrane Database Syst Rev 2:CD007899. 2012
    ..A review of evidence on effectiveness is therefore timely, especially as this is an area of growing interest for funders and governments...
  23. doi Can paying for results help to achieve the Millennium Development Goals? Overview of the effectiveness of results-based financing
    Andrew D Oxman
    Norwegian Knowledge Centre for the Health Services, Oslo, Norway
    J Evid Based Med 2:70-83. 2009
    ..Results-based financing is widely advocated for achieving health goals, including the Millennium Development Goals...
  24. doi Can paying for results help to achieve the Millennium Development Goals? A critical review of selected evaluations of results-based financing
    Andrew D Oxman
    Norwegian Knowledge Centre for the Health Services, Oslo, Norway
    J Evid Based Med 2:184-95. 2009
    ..RBF is being promoted for helping to achieve the Millennium Development Goals (MDGs)...
  25. ncbi The OFF theory of research utilization
    Andrew D Oxman
    Norwegian Health Services Research Centre, Informed Choice Research Department, PO Box 7004, St Olavs Plass, Oslo, Norway
    J Clin Epidemiol 58:113-6; discussion 117-20. 2005
  26. ncbi Use of evidence in WHO recommendations
    Andrew D Oxman
    Norwegian Knowledge Centre for the Health Services, PO Box 7004, St Olavs Plass, N 0130 Oslo, Norway
    Lancet 369:1883-9. 2007
    ..We examined the use of evidence, particularly evidence of effects, in recommendations developed by WHO departments...
  27. pmc Back to thiazide-diuretics for hypertension: reflections after a decade of irrational prescribing
    Atle Fretheim
    Department of Health Services Research, Norwegian Directorate for Health and Social Affairs, N 0031 Oslo, Norway
    BMC Fam Pract 4:19. 2003
    ....
  28. ncbi [Guidelines for pharmacological primary prevention of cardiovascular diseases--who should be treated?]
    Atle Fretheim
    Brannstasjonen legesenter Arendalsvei 26a 4898 Grimstad
    Tidsskr Nor Laegeforen 122:2277-81. 2002
    ..We have used systematic and explicit methods in the development of a new set of recommendations. This is the first of three articles describing these guidelines...
  29. ncbi [Thiazides in the treatment of hypertension]
    Atle Fretheim
    Tidsskr Nor Laegeforen 123:2621. 2003
  30. ncbi [Thiazides (only) and hard endpoints]
    Signe Flottorp
    Tidsskr Nor Laegeforen 124:2277; author reply 2277-8. 2004
  31. pmc Rational Prescribing in Primary Care (RaPP-trial). A randomised trial of a tailored intervention to improve prescribing of antihypertensive and cholesterol-lowering drugs in general practice [ISRCTN48751230]
    Atle Fretheim
    Department of Health Services Research, Norwegian Directorate for Health and Social Affairs, N 0031 Oslo, Norway
    BMC Health Serv Res 3:5. 2003
    ....
  32. ncbi [Which antihypertensive drugs should be used in the primary prevention of cardiovascular disease?]
    Atle Fretheim
    Brannstasjonen legesenter Arendalsvei 26a 4898 Grimstad
    Tidsskr Nor Laegeforen 122:2283-6. 2002
    ..We have used systematic and explicit methods in the development of a new set of recommendations. This is the second of three articles describing these guidelines...
  33. ncbi [Research interpretation]
    Atle Fretheim
    Avdeling for informerte helsebeslutninger, Nasjonalt kunnskapssenter for helsetjenesten, Oslo
    Tidsskr Nor Laegeforen 124:2656-8. 2004
  34. ncbi [Misleading about thiazides]
    Atle Fretheim
    Tidsskr Nor Laegeforen 124:3259-60; author reply 3260. 2004
  35. ncbi [Which cholesterol-lowering drugs should be used in the primary prevention of cardiovascular disease?]
    Atle Fretheim
    Brannstasjonen legesenter Arendalsvei 26a 4898 Grimstad
    Tidsskr Nor Laegeforen 122:2287-8. 2002
    ..We have used systematic and explicit methods in developing a new set of recommendations. This is the last of three articles describing these guidelines...
  36. pmc The potential savings of using thiazides as the first choice antihypertensive drug: cost-minimisation analysis
    Atle Fretheim
    Department of Health Services Research, Norwegian Directorate for Health and Social Affairs, N 0031 Oslo, Norway
    BMC Health Serv Res 3:18. 2003
    ..Despite this, the use of thiazides is much lower than that of other drug-classes. We wanted to estimate the potential for savings if thiazides were used as the first choice drug for the management of uncomplicated hypertension...
  37. ncbi [Guidelines in general practice--are they read and are they used?]
    Shaun Treweek
    Avdeling for informerte helsebeslutninger, Nasjonalt kunnskapssenter for helsetjenesten, Postboks 7004 St Olavs plass, 0130 Oslo
    Tidsskr Nor Laegeforen 125:300-3. 2005
    ..Many guidelines are not developed from systematic models and are not based on high-quality evidence. The existence of a guideline does not in itself lead to changes in practice and many guidelines are not used once they have been issued...
  38. ncbi The relation between methods and recommendations in clinical practice guidelines for hypertension and hyperlipidemia
    Atle Fretheim
    Department of Health Services Research, Norwegian Directorate for Health Social Welfare, PO Box 8054 Dep, N 0031 Oslo, Norway
    J Fam Pract 51:963-8. 2002
    ..To assess the association between methods used to develop clinical practice guidelines and the recommendations that are made...
  39. ncbi [Do the fee-for-service and reimbursement influence medical practice?]
    Atle Fretheim
    Avdeling for helsetjenesteforskning Sosial og helsedirektoratet Postboks 8054 Dep 0031 Oslo
    Tidsskr Nor Laegeforen 123:795-6. 2003
  40. ncbi [Thiazides--good first choice preparations in hypertension]
    Atle Fretheim
    Avdeling for helsetjenesteforskning Sosial og helsedirektoratet Postboks 8054 Dep 0031 Oslo
    Tidsskr Nor Laegeforen 123:1236. 2003
  41. ncbi [Medical research--money or life?]
    Atle Fretheim
    Leger Uten Grenser MSF Norge, Oslo
    Tidsskr Nor Laegeforen 123:2908-9. 2003
  42. ncbi [Shortcomings and strength of practice guidelines]
    Atle Fretheim
    Tidsskr Nor Laegeforen 123:1566-7. 2003
  43. ncbi VALUE: analysis of results
    Atle Fretheim
    Lancet 364:934-5; author reply 935. 2004
  44. ncbi [How do general practice assistants keep themselves up to date?]
    Kari Håvelsrud
    Avdeling for informerte helsebeslutninger, Nasjonalt kunnskapssenter for helsetjenesten, Postboks 7004 St Olavs plass 0130 Oslo
    Tidsskr Nor Laegeforen 125:307-9. 2005
    ....
  45. ncbi [What do general practitioners do to keep themselves up to date?]
    Shaun Treweek
    Avdeling for informerte helsebeslutninger, Nasjonalt kunnskapssenter for helsetjenesten, Postboks 7004 St Olavs plass, 0130 Oslo
    Tidsskr Nor Laegeforen 125:304-6. 2005
    ..Continuing education should ensure that a doctor provides effective care based on the best available evidence. But not all continuing education is equally effective...
  46. ncbi [Drugs against the neglected diseases]
    Atle Fretheim
    Tidsskr Nor Laegeforen 122:2691. 2002