Arild Nesbakken

Summary

Country: Norway

Publications

  1. ncbi [Surgical treatment of colon cancer]
    Arild Nesbakken
    Gastrokirurgisk avdeling, Aker universitetssykehus, 0514 Oslo
    Tidsskr Nor Laegeforen 127:2942-5. 2007
  2. ncbi Endoscopic snare resection followed by laser ablation in the treatment of large, sessile rectal adenomas
    A Nesbakken
    Department of Gastrointestinal Surgery, Oslo University Hospital, Aker, Oslo, Norway
    Scand J Surg 100:99-104. 2011
  3. ncbi Staging of rectal carcinoma with transrectal ultrasonography
    A Nesbakken
    Department of Surgery, Aker University Hospital, Oslo, Norway
    Scand J Surg 92:125-9. 2003
  4. ncbi Anastomotic leak following mesorectal excision for rectal cancer: true incidence and diagnostic challenges
    A Nesbakken
    Department of Surgery, Aker University Hospital, Oslo, Norway
    Colorectal Dis 7:576-81. 2005
  5. doi Establishing laparoscopic Roux-en-Y gastric bypass: perioperative outcome and characteristics of the learning curve
    Torgeir T Søvik
    Faculty of Medicine, University of Oslo, Oslo, Norway
    Obes Surg 19:158-65. 2009
  6. doi Long-term outcome of palliative treatment with self-expanding metal stents for malignant obstructions of the GI tract
    Lene Larssen
    Department of Gastroenterology, Oslo University Hospital, Ulleval, Oslo, Norway
    Scand J Gastroenterol 47:1505-14. 2012
  7. ncbi ColoGuideEx: a robust gene classifier specific for stage II colorectal cancer prognosis
    Trude H Agesen
    Department of Cancer Prevention, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Nydalen, Oslo, Norway
    Gut 61:1560-7. 2012
  8. pmc MiR-9, -31, and -182 deregulation promote proliferation and tumor cell survival in colon cancer
    Lina Cekaite
    Department of Cancer Prevention, Institute for Cancer Research, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway
    Neoplasia 14:868-79. 2012
  9. doi ColoGuidePro: a prognostic 7-gene expression signature for stage III colorectal cancer patients
    Anita Sveen
    Department of Cancer Prevention, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway
    Clin Cancer Res 18:6001-10. 2012
  10. pmc Distinct high resolution genome profiles of early onset and late onset colorectal cancer integrated with gene expression data identify candidate susceptibility loci
    Marianne Berg
    Department of Cancer Prevention, Institute for Cancer Research, Oslo University Hospital, Norwegian Radium Hospital, Oslo, Norway
    Mol Cancer 9:100. 2010

Collaborators

Detail Information

Publications34

  1. ncbi [Surgical treatment of colon cancer]
    Arild Nesbakken
    Gastrokirurgisk avdeling, Aker universitetssykehus, 0514 Oslo
    Tidsskr Nor Laegeforen 127:2942-5. 2007
    ..The incidence of colon cancer is increasing in Norway and about 2200 new cases are now diagnosed each year. This paper presents accepted principles of the surgical treatment of the disease...
  2. ncbi Endoscopic snare resection followed by laser ablation in the treatment of large, sessile rectal adenomas
    A Nesbakken
    Department of Gastrointestinal Surgery, Oslo University Hospital, Aker, Oslo, Norway
    Scand J Surg 100:99-104. 2011
    ..Large sessile rectal adenomas can be difficult to eradicate, and different treatment modalities are available. The aim of this study was to evaluate outcome after endoscopic snare resection followed by Nd:YAG laser ablation...
  3. ncbi Staging of rectal carcinoma with transrectal ultrasonography
    A Nesbakken
    Department of Surgery, Aker University Hospital, Oslo, Norway
    Scand J Surg 92:125-9. 2003
    ..The aim of this study was to audit the introduction of TRUS performed by surgeons without previous experience with ultrasonography...
  4. ncbi Anastomotic leak following mesorectal excision for rectal cancer: true incidence and diagnostic challenges
    A Nesbakken
    Department of Surgery, Aker University Hospital, Oslo, Norway
    Colorectal Dis 7:576-81. 2005
    ..In this study the true incidence of the complication was evaluated, and the diagnostic accuracy of clinical symptoms, conventional rectal radiography (CRR) and computed tomography (CT) was compared...
  5. doi Establishing laparoscopic Roux-en-Y gastric bypass: perioperative outcome and characteristics of the learning curve
    Torgeir T Søvik
    Faculty of Medicine, University of Oslo, Oslo, Norway
    Obes Surg 19:158-65. 2009
    ..Bariatric surgery was established at several Norwegian hospitals in 2004. This study evaluates the perioperative outcome and the learning curves for two surgeons while introducing laparoscopic Roux-en-Y gastric bypass (LRYGB)...
  6. doi Long-term outcome of palliative treatment with self-expanding metal stents for malignant obstructions of the GI tract
    Lene Larssen
    Department of Gastroenterology, Oslo University Hospital, Ulleval, Oslo, Norway
    Scand J Gastroenterol 47:1505-14. 2012
    ..Self-expanding metal stents (SEMS) are commonly used in the palliative treatment of malignant gastrointestinal (GI) obstructions with favorable short-term outcome. Data on long-term outcome are scarce, however...
  7. ncbi ColoGuideEx: a robust gene classifier specific for stage II colorectal cancer prognosis
    Trude H Agesen
    Department of Cancer Prevention, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Nydalen, Oslo, Norway
    Gut 61:1560-7. 2012
    ..The present study aimed to develop a gene expression classifier for improved risk stratification of patients with stage II CRC...
  8. pmc MiR-9, -31, and -182 deregulation promote proliferation and tumor cell survival in colon cancer
    Lina Cekaite
    Department of Cancer Prevention, Institute for Cancer Research, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway
    Neoplasia 14:868-79. 2012
    ..This study suggests that deregulated expression of miR-9, miR-31, and miR-182 during carcinogenesis plays a significant role in the development of colon cancer by promoting proliferation and tumor cell survival...
  9. doi ColoGuidePro: a prognostic 7-gene expression signature for stage III colorectal cancer patients
    Anita Sveen
    Department of Cancer Prevention, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway
    Clin Cancer Res 18:6001-10. 2012
    ..This study was conducted to develop a clinically feasible and robust prognostic classifier for these patients independent of adjuvant treatment...
  10. pmc Distinct high resolution genome profiles of early onset and late onset colorectal cancer integrated with gene expression data identify candidate susceptibility loci
    Marianne Berg
    Department of Cancer Prevention, Institute for Cancer Research, Oslo University Hospital, Norwegian Radium Hospital, Oslo, Norway
    Mol Cancer 9:100. 2010
    ..Integration analysis of CNV and genome wide mRNA expression data, available for the same tumors, was performed to identify a restricted candidate gene list...
  11. pmc Phospholipase C isozymes are deregulated in colorectal cancer--insights gained from gene set enrichment analysis of the transcriptome
    Stine A Danielsen
    Department of Cancer Prevention, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway
    PLoS ONE 6:e24419. 2011
    ..In conclusion, we have identified significantly deregulated pathways in CRC, and validated repression of PLCD1 and PLCE1 expression. This illustrates that the GSEA approach may guide discovery of novel biomarkers in cancer...
  12. doi The exon-level biomarker SLC39A14 has organ-confined cancer-specificity in colorectal cancer
    Anita Sveen
    Department of Cancer Prevention, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway
    Int J Cancer 131:1479-85. 2012
    ..In conclusion, the SLC39A14-exon4B transcript variant is a CRC biomarker with high sensitivity and organ-confined specificity. Further use of the transcript and its encoded protein isoform should be explored in an organ-confined context...
  13. doi Prognostic impact of lymph node harvest and lymph node ratio in patients with colon cancer
    Ole H Sjo
    Department of Gastrointestinal Surgery, Oslo University Hospital Aker, Oslo, Norway
    Dis Colon Rectum 55:307-15. 2012
    ..The prognostic impact of the number of lymph nodes and ratio in colon cancer is still debated...
  14. doi Sentinel node mapping does not improve staging of lymph node metastasis in colonic cancer
    Arne E Faerden
    Department of Digestive Surgery, Akershus University Hospital, University of Oslo, Oslo, Norway
    Dis Colon Rectum 51:891-6. 2008
    ..This study was designed to evaluate the reliability of the sentinel node concept in colonic cancer...
  15. pmc Identification of an epigenetic biomarker panel with high sensitivity and specificity for colorectal cancer and adenomas
    Guro E Lind
    Department of Cancer Prevention, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway
    Mol Cancer 10:85. 2011
    ..This study investigates a panel of epigenetic markers for the detection of colorectal cancer and adenomas...
  16. doi Peritoneal carcinomatosis of colon cancer origin: highest incidence in women and in patients with right-sided tumors
    Ole Helmer Sjo
    Department of Gastrointestinal Surgery, Oslo University Hospital, Aker, Oslo, Norway
    J Surg Oncol 104:792-7. 2011
    ....
  17. pmc A tissue-based comparative effectiveness analysis of biomarkers for early detection of colorectal tumors
    Deeqa Ahmed
    1 Department of Cancer Prevention, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway 2 Centre for Cancer Biomedicine, University of Oslo, Oslo, Norway
    Clin Transl Gastroenterol 3:e27. 2012
    ..In this study, we compared the performance of this novel epi-panel with that of previously identified DNA methylation markers in the same clinical tissue sample sets...
  18. doi Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome
    Solveig Sirnes
    Department of Cancer Prevention, Institute for Cancer Research, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway
    Int J Cancer 131:570-81. 2012
    ..Altogether, these data indicate that Cx43 is a colorectal cancer tumor suppressor protein that predicts clinical outcome...
  19. doi Lymph node micrometastases and isolated tumor cells influence survival in stage I and II colon cancer
    Arne E Faerden
    Department of Digestive Surgery, Akershus University Hospital, University of Oslo, Oslo, Norway
    Dis Colon Rectum 54:200-6. 2011
    ..The aim of the present prospective study was to evaluate the influence of micrometastases and isolated tumor cells on recurrence and disease-free survival in colon cancer...
  20. doi Anticipating the clinical use of prognostic gene expression-based tests for colon cancer stage II and III: is Godot finally arriving?
    Anita Sveen
    Authors Affiliations Department of Cancer Prevention, Institute for Cancer Research, The Norwegian Radium Hospital Departments of Gastrointestinal Surgery and Oncology, Oslo University Hospital and Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Oslo, Norway
    Clin Cancer Res 19:6669-77. 2013
    ..However, microsatellite instability is the only molecular prognostic marker recommended for clinical use...
  21. pmc High frequency of fusion transcripts involving TCF7L2 in colorectal cancer: novel fusion partner and splice variants
    Torfinn Nome
    Department of Cancer Prevention, Institute for Cancer Research, Norwegian Radium Hospital Oslo University Hospital, Oslo, Norway Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Oslo, Norway
    PLoS ONE 9:e91264. 2014
    ..The similar fusion transcripts induced by genomic rearrangements observed in individual cancer cell lines may yet have oncogenic potential as suggested in the original study by Bass et al. ..
  22. pmc DNA sequence profiles of the colorectal cancer critical gene set KRAS-BRAF-PIK3CA-PTEN-TP53 related to age at disease onset
    Marianne Berg
    Department of Cancer Prevention, Institute for Cancer Research, Oslo University Hospital, The Norwegian Radium Hospital, Oslo, Norway
    PLoS ONE 5:e13978. 2010
    ....
  23. pmc Transcriptome instability in colorectal cancer identified by exon microarray analyses: Associations with splicing factor expression levels and patient survival
    Anita Sveen
    Department of Cancer Prevention, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, PO Box 4953 Nydalen, NO 0424 Oslo, Norway
    Genome Med 3:32. 2011
    ..In the present study we analyze genome-wide disruption of pre-mRNA splicing, and propose transcriptome instability as a characteristic that is analogous to genomic instability on the transcriptome level...
  24. pmc Patient-reported outcomes in palliative gastrointestinal stenting: a Norwegian multicenter study
    Lene Larssen
    Department of Medical Gastroenterology, Oslo University Hospital, Ulleval, Oslo, Norway
    Surg Endosc 25:3162-9. 2011
    ....
  25. doi Preoperative staging and treatment options in T1 rectal adenocarcinoma
    Gunnar Baatrup
    Department of Surgery, Haukeland University Hospital, Bergen, Norway
    Acta Oncol 48:328-42. 2009
    ..Subgroups of patients have operative mortality risks of 10% or more. Operative complications and long-term side effects after rectum resection are frequent and often severe...
  26. ncbi Audit of intraoperative and early postoperative complications after introduction of mesorectal excision for rectal cancer
    Arild Nesbakken
    Department of Surgery, Aker Hospital, Oslo, Norway
    Eur J Surg 168:229-35. 2002
    ....
  27. ncbi [Surgical treatment of morbid obesity at a regional center]
    Torgeir T Søvik
    Kirurgisk klinikk, Aker universitetssykehus, 0514 Oslo
    Tidsskr Nor Laegeforen 127:47-9. 2007
    ..This study describes the characteristics of the patients undergoing surgery, the preoperative evaluation and the perioperative outcome after the first 139 laparoscopic procedures for morbid obesity...
  28. ncbi Outcome and late functional results after anastomotic leakage following mesorectal excision for rectal cancer
    A Nesbakken
    Department of Surgery, Aker Hospital, N 0514 Oslo, Norway
    Br J Surg 88:400-4. 2001
    ..Few studies have evaluated the long-term functional outcome after anastomotic leakage in the treatment of rectal cancer...
  29. doi Frailty indicators and functional status in older patients after colorectal cancer surgery
    Benedicte Rønning
    Department of Geriatric Medicine, Oslo University Hospital, PB 4956 Nydalen, 0424 Oslo, Norway Institute of Clinical Medicine, University of Oslo, Oslo, Norway Electronic address
    J Geriatr Oncol 5:26-32. 2014
    ..We aimed to investigate physical function in older patients with colorectal cancer before and after surgery, and to examine the role of individual frailty indicators as predictors of functional decline...
  30. doi Short term outcome after emergency and elective surgery for colon cancer
    O H Sjo
    Department of Gastrointestinal Surgery, Aker University Hospital, Oslo, Norway
    Colorectal Dis 11:733-9. 2009
    ..The purpose of this study was to evaluate postoperative mortality and complications in a consecutive and population based series...
  31. ncbi Local recurrence after mesorectal excision for rectal cancer
    A Nesbakken
    Department of Surgery, Aker Hospital, Oslo, Norway
    Eur J Surg Oncol 28:126-34. 2002
    ..Controversy still exists about the optimal surgical treatment of rectal cancer. The main purpose of the present study was to compare local recurrence (LR) rates after mesorectal excision (ME) and conventional surgery (CS) technique...
  32. ncbi Tumour location is a prognostic factor for survival in colonic cancer patients
    O H Sjo
    Department of Gastrointestinal Surgery, Aker University Hospital, Oslo, Norway
    Colorectal Dis 10:33-40. 2008
    ..To evaluate survival and prognostic factors in a consecutive series of colon cancer patients from a defined city population in Norway...
  33. doi Morbidity related to the use of a protective stoma in anterior resection for rectal cancer
    T Mala
    Surgical Department, Aker University Hospital, Oslo, Norway
    Colorectal Dis 10:785-8. 2008
    ..To evaluate morbidity related to the use of a protective stoma in rectal resection for cancer...
  34. ncbi [Colorectal polyps]
    Bjørn Hofstad
    Gastromedisinsk avdeling, Ulleval universitetssykehus, 0407 Oslo
    Tidsskr Nor Laegeforen 127:2692-5. 2007
    ..There is circumstantial evidence that most cancers develop from polyps; so detection, eradication and follow-up stategies for polyps are important. The article provides an update on these topics...