Line M Jacobsen

Summary

Affiliation: National Institute of Occupational Health
Country: Norway

Publications

  1. doi The COMT rs4680 Met allele contributes to long-lasting low back pain, sciatica and disability after lumbar disc herniation
    L M Jacobsen
    National Institute of Occupational Health, Oslo, Norway
    Eur J Pain 16:1064-9. 2012
  2. doi Catechol-O-methyltransferase (COMT) inhibition reduces spinal nociceptive activity
    Line M Jacobsen
    National Institute of Occupational Health, Oslo, Norway
    Neurosci Lett 473:212-5. 2010
  3. doi Induction of the perceptual correlate of human long-term potentiation (LTP) is associated with the 5-HTT genotype
    Dagfinn Matre
    National Institute of Occupational Health, Oslo, Norway
    Brain Res 1491:54-9. 2013
  4. doi Spinal cord long-term potentiation (LTP) is associated with increased dorsal horn gene expression of IL-1beta, GDNF and iNOS
    Linda M Pedersen
    National Institute of Occupational Health, Oslo, Norway
    Eur J Pain 14:255-60. 2010
  5. doi The interleukin-1α gene C>T polymorphism rs1800587 is associated with increased pain intensity and decreased pressure pain thresholds in patients with lumbar radicular pain
    Elina I Schistad
    Department of Physical Medicine and Rehabilitation, Oslo University Hospital, Ullevaal Faculty of Medicine Department of Molecular Biosciences, University of Oslo National Institute of Occupational Health, Oslo, Norway
    Clin J Pain 30:869-74. 2014

Collaborators

Detail Information

Publications5

  1. doi The COMT rs4680 Met allele contributes to long-lasting low back pain, sciatica and disability after lumbar disc herniation
    L M Jacobsen
    National Institute of Occupational Health, Oslo, Norway
    Eur J Pain 16:1064-9. 2012
    ..A functional polymorphism in the gene encoding this enzyme, i.e. the COMT Val158Met SNP that reduces enzyme activity, has previously been linked to pain sensitivity...
  2. doi Catechol-O-methyltransferase (COMT) inhibition reduces spinal nociceptive activity
    Line M Jacobsen
    National Institute of Occupational Health, Oslo, Norway
    Neurosci Lett 473:212-5. 2010
    ..01, HFS vs. HFS+OR 486). Our findings suggest that low COMT activity may have an antinociceptive effect in the spinal cord...
  3. doi Induction of the perceptual correlate of human long-term potentiation (LTP) is associated with the 5-HTT genotype
    Dagfinn Matre
    National Institute of Occupational Health, Oslo, Norway
    Brain Res 1491:54-9. 2013
    ..Taken together, this suggests that the expression of 5-HTT, may be important for induction of LTP in humans...
  4. doi Spinal cord long-term potentiation (LTP) is associated with increased dorsal horn gene expression of IL-1beta, GDNF and iNOS
    Linda M Pedersen
    National Institute of Occupational Health, Oslo, Norway
    Eur J Pain 14:255-60. 2010
    ..05, HFS vs. control). For the first time we show that spinal cord LTP is associated with an increased dorsal horn expression of the genes for IL-1beta, GDNF and iNOS...
  5. doi The interleukin-1α gene C>T polymorphism rs1800587 is associated with increased pain intensity and decreased pressure pain thresholds in patients with lumbar radicular pain
    Elina I Schistad
    Department of Physical Medicine and Rehabilitation, Oslo University Hospital, Ullevaal Faculty of Medicine Department of Molecular Biosciences, University of Oslo National Institute of Occupational Health, Oslo, Norway
    Clin J Pain 30:869-74. 2014
    ..In the present study, we examined how variability of the IL-1α gene affects pain intensity and the pressure pain threshold (PPT) in patients with symptomatic disk herniation...