Pedro Araujo

Summary

Affiliation: National Institute of Nutrition and Seafood Research
Country: Norway

Publications

  1. ncbi request reprint The impact of exogenous ω-6 and ω-3 polyunsaturated fatty acids on the induced production of pro- and anti-inflammatory prostaglandins and leukotrienes in Atlantic salmon head kidney cells using a full factorial design and LC-MS/MS
    Pedro Araujo
    National Institute of Nutrition and Seafood Research NIFES, PO Box 2029 Nordnes, N 5817 Bergen, Norway Electronic address
    J Chromatogr B Analyt Technol Biomed Life Sci 964:164-71. 2014
  2. ncbi request reprint Development and validation of an extraction method for the determination of pro-inflammatory eicosanoids in human plasma using liquid chromatography-tandem mass spectrometry
    Pedro Araujo
    National Institute of Nutrition and Seafood Research NIFES, PO Box 2029 Nordnes, N 5817 Bergen, Norway Electronic address
    J Chromatogr A 1353:57-64. 2014
  3. doi request reprint Determination and structural elucidation of triacylglycerols in krill oil by chromatographic techniques
    Pedro Araujo
    National Institute of Nutrition and Seafood Research NIFES, PO Box 2029, Nordnes, 5817, Bergen, Norway
    Lipids 49:163-72. 2014
  4. doi request reprint Doehlert uniform shell designs and chromatography
    Pedro Araujo
    National Institute of Nutrition and Seafood Research NIFES, PO Box 2029 Nordnes, N 5817 Bergen, Norway
    J Chromatogr B Analyt Technol Biomed Life Sci 910:14-21. 2012
  5. doi request reprint Application of Doehlert uniform shell designs for selecting optimal amounts of internal standards in the analysis of prostaglandins and leukotrienes by liquid chromatography-tandem mass spectrometry
    Pedro Araujo
    National Institute of Nutrition and Seafood Research NIFES, PO Box 2029, Nordnes, N 5817 Bergen, Norway
    J Chromatogr A 1260:102-10. 2012
  6. ncbi request reprint Chemometric approaches in calibration experiments of trilinolenoylglycerol by liquid chromatography ion-trap mass spectrometry
    Pedro Araujo
    Seafood and Health Research Group, National Institute of Nutrition and Seafood Research, N 5817 Bergen, Norway
    J Am Soc Mass Spectrom 16:388-96. 2005
  7. pmc Discrimination of n-3 rich oils by gas chromatography
    Pedro Araujo
    National Institute of Nutrition and Seafood Research NIFES, PO Box 2029, Nordnes, 5817, Bergen, Norway
    Lipids 45:1147-58. 2010
  8. pmc Evaluation of a rapid method for the quantitative analysis of fatty acids in various matrices
    Pedro Araujo
    National Institute of Nutrition and Seafood Research, N 5817 Bergen, Norway
    J Chromatogr A 1212:106-13. 2008
  9. ncbi request reprint Improved quantification of prostaglandins in biological samples by optimizing simultaneously the relationship eicosanoid/internal standard and using liquid chromatography tandem mass spectrometry
    Pedro Araujo
    National Institute of Nutrition and Seafood Research NIFES, PO Box 2029 Nordnes, N 5817 Bergen, Norway
    Prostaglandins Leukot Essent Fatty Acids 77:9-13. 2007
  10. ncbi request reprint Statistical power and analytical quantification
    Pedro Araujo
    National Institute of Nutrition and Seafood Research NIFES, P O Box 2029 Nordnes, N 5817 Bergen, Norway
    J Chromatogr B Analyt Technol Biomed Life Sci 847:305-8. 2007

Collaborators

Detail Information

Publications22

  1. ncbi request reprint The impact of exogenous ω-6 and ω-3 polyunsaturated fatty acids on the induced production of pro- and anti-inflammatory prostaglandins and leukotrienes in Atlantic salmon head kidney cells using a full factorial design and LC-MS/MS
    Pedro Araujo
    National Institute of Nutrition and Seafood Research NIFES, PO Box 2029 Nordnes, N 5817 Bergen, Norway Electronic address
    J Chromatogr B Analyt Technol Biomed Life Sci 964:164-71. 2014
    ....
  2. ncbi request reprint Development and validation of an extraction method for the determination of pro-inflammatory eicosanoids in human plasma using liquid chromatography-tandem mass spectrometry
    Pedro Araujo
    National Institute of Nutrition and Seafood Research NIFES, PO Box 2029 Nordnes, N 5817 Bergen, Norway Electronic address
    J Chromatogr A 1353:57-64. 2014
    ..The recovery ranges were 95.1-104.7% for PGE2 and 86.4-103.2% for LTB4. The developed method was successfully implemented on plasma samples from patients before and after exposure to certain anti-inflammatory treatment. ..
  3. doi request reprint Determination and structural elucidation of triacylglycerols in krill oil by chromatographic techniques
    Pedro Araujo
    National Institute of Nutrition and Seafood Research NIFES, PO Box 2029, Nordnes, 5817, Bergen, Norway
    Lipids 49:163-72. 2014
    ..It was estimated that 21 % of n-3 PUFA were at the sn-2 position of TAG structures. To our knowledge, this is the first determination and structural characterization of TAG in pure krill oil supplements. ..
  4. doi request reprint Doehlert uniform shell designs and chromatography
    Pedro Araujo
    National Institute of Nutrition and Seafood Research NIFES, PO Box 2029 Nordnes, N 5817 Bergen, Norway
    J Chromatogr B Analyt Technol Biomed Life Sci 910:14-21. 2012
    ..The article provides an overview of analytical applications in chromatography with focus on single and coupled techniques and also discusses some reported blunders regarding Doehlert designs...
  5. doi request reprint Application of Doehlert uniform shell designs for selecting optimal amounts of internal standards in the analysis of prostaglandins and leukotrienes by liquid chromatography-tandem mass spectrometry
    Pedro Araujo
    National Institute of Nutrition and Seafood Research NIFES, PO Box 2029, Nordnes, N 5817 Bergen, Norway
    J Chromatogr A 1260:102-10. 2012
    ....
  6. ncbi request reprint Chemometric approaches in calibration experiments of trilinolenoylglycerol by liquid chromatography ion-trap mass spectrometry
    Pedro Araujo
    Seafood and Health Research Group, National Institute of Nutrition and Seafood Research, N 5817 Bergen, Norway
    J Am Soc Mass Spectrom 16:388-96. 2005
    ..The error decomposition approach revealed that the preparation error was 26 times higher than the instrumental error...
  7. pmc Discrimination of n-3 rich oils by gas chromatography
    Pedro Araujo
    National Institute of Nutrition and Seafood Research NIFES, PO Box 2029, Nordnes, 5817, Bergen, Norway
    Lipids 45:1147-58. 2010
    ..GC offers a rapid, simple and convenient means of discriminating oils from different species, brands and grades...
  8. pmc Evaluation of a rapid method for the quantitative analysis of fatty acids in various matrices
    Pedro Araujo
    National Institute of Nutrition and Seafood Research, N 5817 Bergen, Norway
    J Chromatogr A 1212:106-13. 2008
    ..A mechanism underlying this effect is proposed...
  9. ncbi request reprint Improved quantification of prostaglandins in biological samples by optimizing simultaneously the relationship eicosanoid/internal standard and using liquid chromatography tandem mass spectrometry
    Pedro Araujo
    National Institute of Nutrition and Seafood Research NIFES, PO Box 2029 Nordnes, N 5817 Bergen, Norway
    Prostaglandins Leukot Essent Fatty Acids 77:9-13. 2007
    ..The results revealed that the interaction eicosanoid/internal standard is an important factor that affects the validity of the RF and subsequently the accuracy of the analysis...
  10. ncbi request reprint Statistical power and analytical quantification
    Pedro Araujo
    National Institute of Nutrition and Seafood Research NIFES, P O Box 2029 Nordnes, N 5817 Bergen, Norway
    J Chromatogr B Analyt Technol Biomed Life Sci 847:305-8. 2007
    ..Illustrative examples from the literature are used to show how the described power analysis theory could be applied in practice...
  11. ncbi request reprint Experimental design considerations in quantification experiments by using the internal standard technique: cholesterol determination by gas chromatography as a case study
    Pedro Araujo
    National Institute of Nutrition and Seafood Research NIFES, P O Box 2029 Nordnes, N 5817 Bergen, Norway
    J Chromatogr A 1121:99-105. 2006
    ..The outlined approaches can be applied in the determination of any kind of analyte...
  12. doi request reprint Key aspects of analytical method validation and linearity evaluation
    Pedro Araujo
    National Institute of Nutrition and Seafood Research, PO Box 2029, Nordnes, N 5817 Bergen, Norway
    J Chromatogr B Analyt Technol Biomed Life Sci 877:2224-34. 2009
    ....
  13. ncbi request reprint Optimisation of an extraction method for the determination of prostaglandin E2 in plasma using experimental design and liquid chromatography tandem mass spectrometry
    Pedro Araujo
    National Institute of Nutrition and Seafood Research NIFES, P O Box 2029 Nordnes, N 5817 Bergen, Norway
    J Chromatogr B Analyt Technol Biomed Life Sci 830:212-7. 2006
    ..5 pg for an injection volume of 25 microl. The optimised extraction method showed high reproducibility (coefficients of variation<4%) and recovery values, estimated from standard addition experiments, ranging from 96 to 98%...
  14. ncbi request reprint Cytokine gene expression and prostaglandin production in head kidney leukocytes isolated from Atlantic cod (Gadus morhua) added different levels of arachidonic acid and eicosapentaenoic acid
    Miriam Furné
    National Institute of Nutrition and Seafood Research NIFES, P B 2029 Nordnes, 5817 Bergen, Norway
    Fish Shellfish Immunol 34:770-7. 2013
    ....
  15. doi request reprint Elucidation of triacylglycerols in cod liver oil by liquid chromatography electrospray tandem ion-trap mass spectrometry
    Ying Xu Zeng
    National Institute of Nutrition and Seafood Research NIFES, PO Box 2029, Nordnes, N 5817 Bergen, Norway
    Talanta 82:1261-70. 2010
    ..The results were compared against the lipase benchmark method. A principal component analysis study revealed that it is possible to discriminate genuine from adulterated cod liver oil...
  16. doi request reprint Development of an extraction method for the determination of prostaglandins in biological tissue samples using liquid chromatography-tandem mass spectrometry: application to gonads of Atlantic cod (Gadus morhua)
    Steve Janagap
    National Institute of Nutrition and Seafood Research, PO Box 2029 Nordnes, N 5817 Bergen, Norway
    Anal Chim Acta 749:51-5. 2012
    ..999±0.002 and 99.967±0.023 respectively. The homogenization of samples using liquid nitrogen combined with the developed extraction protocol can be implemented in different types of biological tissues...
  17. pmc UCP1 induction during recruitment of brown adipocytes in white adipose tissue is dependent on cyclooxygenase activity
    Lise Madsen
    Department of Biology, University of Copenhagen, Copenhagen, Denmark
    PLoS ONE 5:e11391. 2010
    ..The uncoupling protein 1 (UCP1) is a hallmark of brown adipocytes and pivotal for cold- and diet-induced thermogenesis...
  18. doi request reprint Pathogen recognition and mechanisms in Atlantic cod (Gadus morhua) head kidney cells: bacteria (LPS) and virus (poly I:C) signals through different pathways and affect distinct genes
    Elisabeth Holen
    National Institute of Nutrition and Seafood Research NIFES, Bergen, Norway
    Fish Shellfish Immunol 33:267-76. 2012
    ..In addition, the novel finding that cytochrome P450 1A was upregulated during the antibacterial response indicates a connection between immunity and aryl hydrocarbon receptor activation in Atlantic cod...
  19. doi request reprint A randomized double blind comparison of short-term duodenally administrated whale and seal blubber oils in patients with inflammatory bowel disease and joint pain
    Tormod Bjørkkjaer
    National Institute of Nutrition and Seafood Research NIFES, P O Box 2029 Nordnes, N 5817 Bergen, Norway
    Prostaglandins Leukot Essent Fatty Acids 81:425-32. 2009
    ..These changes were not significantly different between SO and WO groups. Inhibition of cyclooxygenase is consistent with amelioration of IBD-related joint pain, but, as active control was used, effects need confirmation...
  20. doi request reprint Direct determination of serotonin in gut lavage fluid by liquid chromatographic ion trap tandem mass spectrometry
    Kine Gregersen
    National Institute of Nutrition and Seafood Research NIFES, P O Box 2029, Nordnes, N 5817 Bergen, Norway
    Talanta 75:466-72. 2008
    ..The relationship 5-HT/5-CH3O-HT was modelled by using a simultaneous design in order to estimate the optimal amount of internal standard to be added to the samples prior to quantification...
  21. doi request reprint Evaluation of different fingerprinting strategies for differentiating marine oils by liquid chromatography ion-trap mass spectrometry and chemometrics
    Yingxu Zeng
    National Institute of Nutrition and Seafood Research NIFES, PO Box 2029 Nordnes, N 5817, Bergen, Norway
    Analyst 136:1507-14. 2011
    ..This novel approach represents an alternative and promising tool for fingerprinting and differentiating marine oils...
  22. ncbi request reprint A co culture approach show that polyamine turnover is affected during inflammation in Atlantic salmon immune and liver cells and that arginine and LPS exerts opposite effects on p38MAPK signaling
    Elisabeth Holen
    National Institute of Nutrition and Seafood Research NIFES, P B 2029 Nordnes, 5817 Bergen, Norway Electronic address
    Fish Shellfish Immunol 37:286-98. 2014
    ..This paper shows that co culturing these two cell types reveals the connection between metabolism and inflammation, suggesting different pathways and candidate biomarkers to be further explored. ..