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Publications
The effect of endotoxin on the production of IgE, IgG1 and IgG2a antibodies against the cat allergen Fel d 1 in miceHeidi Ormstad
Department of Environmental Immunology, Division of Environmental Medicine, Norwegian Institute of Public Health, P O Box 4404 Nydalen, N 0403, Oslo, Norway
Toxicology 188:309-18. 2003..Some have reported a positive correlation between the level of LPS in house dust and the symptoms of asthmatic children. Others have found that exposure to LPS appears to protect against the development of atopic disease in children...
A randomized controlled trial of two strategies to implement active sick leave for patients with low back painInger B Scheel
Health Services Research Unit, National Institute of Public Health, Oslo, Norway
Spine (Phila Pa 1976) 27:561-6. 2002..Cluster randomized controlled trial...
[Can disinfectants contribute to antibiotic resistance?]E Heir
Statens institutt for folkehelse Postboks 4404 Nydalen 0403 Oslo
Tidsskr Nor Laegeforen 121:3201-6. 2001..Increasingly, disinfectants are included in consumer products. Broad-scale use of antiseptics and disinfectants may have detrimental ecological consequences, for instance the development of antimicrobial resistance...
[Elective surgery--cancellations, ring fencing and efficiency]M Aaserud
Avdeling for samfunnsmedisin Statens institutt for folkehelse Postboks 4404 Nydalen 0403 Oslo
Tidsskr Nor Laegeforen 121:2516-9. 2001..We looked at the evidence of whether ring fencing elective surgery is an effective strategy to reduce disturbance from emergency activities, and improve the overall efficiency in hospitals with emergency as well as elective activities...
Measures of goal attainment and performance in the World Health Report 2000: a brief, critical consumer guideErik Nord
National Institute of Public Health, PO Box 4404 Nydalen, 0403, Oslo, Norway
Health Policy 59:183-91. 2002..The WHO needs to add an indicator of equality in access to its present indicator of fairness in financing...
Risk behavior in Norwegian blood donorsH Stigum
Department of Epidemiology, National Institute of Public Health, Oslo, Norway
Transfusion 41:1480-5. 2001..The purpose of this study is to describe the risk behavior for sexually transmitted diseases in Norwegian blood donors...
Is preeclampsia an infectious disease?L I Trogstad
Department of Population Health, National Institute of Public Health, P O Box 4404 Nydalen, 0403 Oslo, Norway
Acta Obstet Gynecol Scand 80:1036-8. 2001..The aim of this study was to assess the impact of being seronegative for some viruses transmitted by close contact on the risk of developing preeclampsia...
[When will mammography screening reduce breast cancer mortality?]B H Strand
Avdeling for samfunnsmedisin Statens institutt for folkehelse Postboks 4404 Nydalen 0403 Oslo
Tidsskr Nor Laegeforen 121:2390-2. 2001..The Cancer Registry of Norway maintains that there will be at least a 30% reduction in mortality, but that an effect may not be detected until the ten-year follow-up...
Yeast colonization in surgical patients with intra-abdominal perforationsP Sandven
Department of Bacteriology, National Institute of Public Health, Oslo, Norway
Eur J Clin Microbiol Infect Dis 20:475-81. 2001..This does not mean that yeast colonization is insignificant; however, more accurate criteria and methods based on prospective clinical studies are needed to detect patients at risk of developing severe Candida infection...
Obesity and associated factors in a Palestinian West Bank village populationL C Stene
Institute for Nutrition Research, University of Oslo, Oslo, Norway
Eur J Clin Nutr 55:805-11. 2001..To describe body mass index (BMI), waist circumference and waist-hip ratio in a Palestinian West Bank village population, and to assess the associations of these variables to blood pressure and serum lipids...
Rat lung inflammatory responses after in vivo and in vitro exposure to various stone particlesR Becher
Department of Environmental Medicine, Section for Air Pollution and Noise, National Institute of Public Health, PO Box 4404, Nydalen, N 0403, Oslo, Norway
Inhal Toxicol 13:789-805. 2001..The results suggest the alveolar type 2 cell to be an important participant in the inflammatory response following exposure to particles...
[Should school children receive pertussis vaccine?]S Sandbu
Avdeling for vaksine, Statens Institutt for Folkehelse, Postboks 4404 Nydalen, 0403 Oslo
Tidsskr Nor Laegeforen 121:1464-8. 2001..The pertussis epidemic in Norway 1997-98 demonstrated decreasing vaccine immunity from age 5-6 years. The possibility of improving immunity against both diseases by a booster dose during early school age is therefore under consideration...
[Airborne dust particles in indoor environment and allergy]H Ormstad
Avdeling for miljømedisin, Statens Institutt for Folkehelse, Postboks 4404, Nydalen, 0403 Oslo
Tidsskr Nor Laegeforen 121:1344-50. 2001..The overall aim of this study was to investigate how airborne house dust particles may contribute to an allergic immune response, and thereby also to asthma and allergic diseases...
Persistent versus transient map kinase (ERK) activation in the proliferation of lung epithelial type 2 cellsE V Thrane
Department of Environmental Medicine, National Institute of Public Health, Oslo, Norway
Exp Lung Res 27:387-400. 2001..The results indicate that a persistent ERK activation of a critical size leads to type 2 cell proliferation, and that the proliferative response may also depend on a MEK-independent ERK activation...
Active sick leave for patients with back pain: all the players onside, but still no actionInger B Scheel
Health Services Research Unit, National Institute of Public Health, Oslo, Norway
Spine (Phila Pa 1976) 27:654-9. 2002..Semistructured interviews, group discussions, and a mailed survey...
Mineral composition other than quartz is a critical determinant of the particle inflammatory potentialPer E Schwarze
Department of Environmental Medicine, National Institute of Public Health, 4404 Nydalen, N 0403 Oslo, Norway
Int J Hyg Environ Health 204:327-31. 2002....
No evidence of an epidemic of locally acquired heterosexual HIV infection in NorwayPreben Aavitsland
Section for Infectious Disease Control, National Institute of Public Health, P O Box 4404, Nydalen 0403, Oslo, Norway
Sex Transm Dis 29:222-7. 2002..An early sign of a major heterosexual human immunodeficiency virus (HIV) epidemic will be heterosexual infection acquired from persons who were themselves infected through heterosexual intercourse...
Regression analysis with multiplicative and time-varying additive regression coefficients with examples from breast and colon cancerPer Henrik Zahl
Section of Medical Statistics, University of Oslo, Norway
Stat Med 22:1113-27. 2003..The method is applied on 3201 female breast cancer and 1372 male colon cancer patients...
Hearing loss induced by noise, ear infections, and head injuries: results from the Nord-Trøndelag Hearing Loss StudyKristian Tambs
Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway
Int J Audiol 42:89-105. 2003..No significant effects of frequent use of personal stereo players or regular attendance at discotheques or rock concerts could be demonstrated. There were clear effects of recurrent ear infections and head injury...
Depression in postpartum and non-postpartum women: prevalence and risk factorsM Eberhard-Gran
Section of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway
Acta Psychiatr Scand 106:426-33. 2002..The aim of the study was to assess the prevalence of depression in postpartum women as compared with non-postpartum women, and to identify risk factors of depression in both groups...
Failure to detect Chlamydia pneumoniae in aortic valves and peripheral blood mononuclear cells from patients undergoing aortic valve replacement in NorwayKirsti Vainio
Division for Infectious Disease Control, Norwegian Institute for Public Health, Oslo
Scand J Infect Dis 34:660-3. 2002..pneumoniae IgG. These results do not support the association of C. pneumoniae with aortic valves and peripheral blood mononuclear cells in patients with atherosclerotic aortic heart valve disease...
Maternal allergen immunization during pregnancy in a mouse model reduces adult allergy-related antibody responses in the offspringI Melkild
Division of Environmental Medicine, Norwegian Institute of Public Health, Oslo, Norway
Clin Exp Allergy 32:1370-6. 2002..This relationship may be important both for allergen avoidance strategies and, alternatively, for allergy prophylaxis by allergen exposure of the mother...
[Blood type diet--visionary science or nonsense?]Helle Margrete Meltzer
Tidsskr Nor Laegeforen 122:1402-5. 2002
The heavier the better? Birthweight and perinatal mortality in different ethnic groupsSiri Vangen
Department of Obstetrics and Gynaecology, The National Hospital, N 0027 Oslo, Norway
Int J Epidemiol 31:654-60. 2002..Given the close relation between birthweight and perinatal mortality, we explored whether ethnic differences in birthweight explain ethnic differences in perinatal mortality...
[HIV infection from Africa to Norway]P Aavitsland
Seksjon for forebyggende infeksjonsmedisin Statens institutt for folkehelse Postboks 4404 Torshov 0403 Oslo
Tidsskr Nor Laegeforen 121:76-9. 2001..Africans seek asylum in Norway and some Norwegians work for longer periods in Africa. We used the Norwegian surveillance system for communicable diseases (1983-99) to assess the connections between the Norwegian and African epidemics...
Brominated flame retardants in archived serum samples from Norway: a study on temporal trends and the role of ageCathrine Thomsen
National Institute of Public Health, Oslo, Norway
Environ Sci Technol 36:1414-8. 2002..The present study indicates an ongoing increase in human exposure to BFRs, and the current body burden appears to be independent of age, except for infants (0-4 years old), who seem to experience elevated exposure...
Interference of an apcA insertion with complementary chromatic adaptation in the diazotrophic Synechocystis sp. strain BO 8402Olaf Neuschaefer-Rube
Lehrstuhl für Physiologie und Biochemie der Pflanzen, Universitat Konstanz, D 78457 Konstanz, Germany
Biochim Biophys Acta 1553:279-95. 2002..No such links could be established. We therefore concluded that in these diazotrophic Synechocystis-type cyanobacteria the green light-induced transcription of the cpe operon directly required a functional apc operon...
Significance of Candida recovered from intraoperative specimens in patients with intra-abdominal perforationsPer Sandven
Department of Bacteriology, Norwegian Institute of Public Health, Oslo
Crit Care Med 30:541-7. 2002....
The effect of respiratory tract infections on reported asthma symptomsWenche Nystad
Department of Population Health Sciences, National Institute of Public Health, Oslo, Norway
Scand J Public Health 30:70-5. 2002..Wheezing and chest tightness is associated with respiratory tract infections. Thus the occurrence of respiratory tract infections may influence the prevalence of asthma...
[Registration of injuries with the help of ICD-10 at Norwegian hospitals]A Sjølingstad
Statens institutt for folkehelse Avdeling for samfunnsmedisin Postboks 4404 Torshov 0403 Oslo
Tidsskr Nor Laegeforen 121:1052-4. 2001..The aim of this study was to find out to what extent the codes for external causes of injury were utilised by the hospitals...
Birth weight and childhood onset type 1 diabetes: population based cohort studyL C Stene
Section of Epidemiology, Department of Population Health Sciences, National Institute of Public Health, Nydalen, N 0403 Oslo, Norway
BMJ 322:889-92. 2001..To assess the associations between birth weight or gestational age and risk of type 1 diabetes...
A variation of the amplified-fragment length polymorphism (AFLP) technique using three restriction endonucleases, and assessment of the enzyme combination BglII-MfeI for AFLP analysis of Salmonella enterica subsp. enterica isolatesB A Lindstedt
Department of Bacteriology, National Institute of Public Health, Oslo, Norway
FEMS Microbiol Lett 189:19-24. 2000..The three-enzyme combination gave a higher discrimination, and is thus a new alternate way of performing AFLP fingerprinting of S. typhimurium...
Symptoms of anxiety and depression among mothers of pre-school children: effect of chronic strain related to children and child care-takingA Naerde
Section of Epidemiology, Department of Population Health Sciences, The National Institute of Public Health, P B 4404, Torshov, N 0403, Oslo, Norway
J Affect Disord 58:181-99. 2000..This study follows up previous work on the influence of social class, strain and social support on maternal mental distress when the children were 18 months old...
Induction of antigen-specific T cell responses in human volunteers after intranasal immunization with a whole-cell pertussis vaccineA K Berstad
Department of Vaccinology, National Institute of Public Health, P O Box 4404 Torshov, N 0403, Oslo, Norway
Vaccine 18:2323-30. 2000..This demonstrates that intranasal administration of a non-proliferating bacterial vaccine without any additional mucosal adjuvant can induce vaccine-specific T cell responses related to mucosal IgA secretion...
Use of transgenic mice in identifying chemopreventive agentsJ Alexander
Department of Environmental Medicine, National Institute of Public Health, 0403, Oslo, Norway
Toxicol Lett 112:507-12. 2000..Transgenic cancer models demonstrate a strong gene-environment interaction, which is promising for the development of chemopreventive strategies...
Asthma and wheezing among Norwegian elite athletesW Nystad
Department of Population Health Sciences, National Institute of Public Health, Oslo
Med Sci Sports Exerc 32:266-70. 2000....
Pneumococcal vaccine in the elderly: the Norwegian experienceI S Aaberge
Department of Vaccinology, National Institute of Public Health, Oslo, Norway
Drugs Aging 15:37-41. 1999..In 1996, the Advisory Board of Infectious Disease Control, National Institute of Public Health, Norway, recommended that pneumococcal polysaccharide vaccine should be administered to all ..
Protective effect of beta-glucan against systemic Streptococcus pneumoniae infection in miceG Hetland
Department of Environmental Medicine, National Institute of Public Health, Oslo, Norway
FEMS Immunol Med Microbiol 27:111-6. 2000..SSG injected 24 h post-challenge had a curative effect against type 6B but not type 4 pneumococcal infection. The data demonstrate that SSG administered systemically protects against pneumococcal infection in mice...
Day care attendance, recurrent respiratory tract infections and asthmaW Nystad
Section of Epidemiology, Department of Population Health Sciences, National Institute of Public Health, Oslo, Norway
Int J Epidemiol 28:882-7. 1999..Our objective was to use a causal model for childhood asthma to determine whether the effect of day care attendance on asthma was mediated by recurrent respiratory tract infections...
Importance of selective media for recovery of yeasts from clinical specimensP Sandven
Department of Bacteriology, National Institute of Public Health, 0462 Oslo, Norway
J Clin Microbiol 37:3731-2. 1999..It is also important that selective fungal media be used in clinical studies of yeast infections...
The drinking water chlorination by-products 3,4-dichloro-5-hydroxy-2[5H]-furanone(mucochloric acid) and 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone do not induce preneoplastic or neoplastic intestinal lesions in F344 rats, balb/ca mice or C57bl/6I L Steffensen
National Institute of Public Health, Department of Environmental Medicine, Oslo
Pharmacol Toxicol 85:56-64. 1999..Based on an overall evaluation of these experiments, the intestinal tract, at least in rats and mice, seems not to be a main target organ for effects of MCA or MX on preneoplastic or neoplastic development...
Identification and characterization of quaternary ammonium compound resistant staphylococci from the food industryE Heir
MATFORSK, Norwegian Food Research Institute, As, Norway
Int J Food Microbiol 48:211-9. 1999..One QAC resistant strain harbouring the smr gene showed resistance to ampicillin, penicillin, tetracycline, erythromycin and trimethoprim. No enterotoxin production was detected among the QAC resistant strains...
Redesignation of a purported P1.15 subtype-specific meningococcal monoclonal antibody as a P1.19-specific reagentE Wedege
Department of Vaccinology, Department of Bacteriology, National Institute of Public Health, N 0403 Oslo, Norway
Clin Diagn Lab Immunol 6:639-42. 1999..Cyanogen bromide cleavage of P1.19,15 PorA, peptide mapping, and sequencing of porA regions demonstrated that 2-1-P1.15 was specific for subtype P1.19, and henceforth it is to be redesignated as 2-1-P1.19...
Occurrence of mites in Norway and the rest of ScandinaviaR Mehl
Laboratory for Entomology, National Institute of Public Health, Oslo, Norway
Allergy 53:28-35. 1998..The number of mites per area indicates the number of mites in the home. The number of mites per weight unit of dust describes the concentration of mites in the vacuum cleaner...
Age-dependent induction of aberrant crypt foci in rat colon by 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine and azoxymethaneJ E Paulsen
Department of Environmental Medicine, National Institute of Public Health, Oslo, Norway
Pharmacol Toxicol 87:69-73. 2000..01). Based on the assumption that the formation of ACF with high multiplicity is predicative for the tumour development we conclude that neonatal rats are more susceptible to PhIP and azoxymethane than adult rats...
The fungal cell wall component beta-1,3-glucan has an adjuvant effect on the allergic response to ovalbumin in miceH Ormstad
Department of Environmental Medicine, National Institute of Public Health, Oslo, Norway
J Toxicol Environ Health A 61:55-67. 2000..A similar increase was not found for IgG2a. Our results show that beta-1,3-D-glucan provides a clear Th2-dependent (allergic) immune response to OA, indicated by elevated levels of IgE and IgG1 and not IgG2a, in the mouse model used...
Protective effect of Plantago major L. Pectin polysaccharide against systemic Streptococcus pneumoniae infection in miceG Hetland
Department of Environmental Medicine, National Institute of Public Health, Oslo, Norway
Scand J Immunol 52:348-55. 2000..major protects against pneumococcal infection in mice when administered systemically prechallenge, and secondly that the protective effect is owing to stimulation of the innate and not the adaptive immune system...
Comparison of capsid sequences from human and animal astrovirusesC M Jonassen
Department of Virology, National Institute of Public Health, PO Box 4404 Torshov, N 0403 Oslo, Norway
J Gen Virol 82:1061-7. 2001..Higher similarities between the HAstV, FAstV and PAstV capsid sequences suggest interspecies transmissions involving humans, cats and pigs relatively recently in the evolutionary history of astroviruses...
[Day care centers, infections and asthma]W Nystad
Seksjon for epidemiologi Avdeling for samfunnsmedisin Statens institutt for folkehelse Postboks 4404 Torshov 0403 Oslo
Tidsskr Nor Laegeforen 121:282-6. 2001..Our objective was to use a causal model for childhood asthma to determine whether the effect of day care attendance on asthma was mediated by recurrent respiratory tract infections...
Determination of phenolic flame-retardants in human plasma using solid-phase extraction and gas chromatography-electron-capture mass spectrometryC Thomsen
National Institute of Public Health, Oslo, Norway
J Chromatogr B Biomed Sci Appl 750:1-11. 2001..The estimated detection limits of TriBP, PeBP, TCBP-A and TBBP-A were 0.3, 0.4, 3.0 and 0.8 pg g(-1) plasma, respectively. The method has been used for analysis of plasma samples from potentially occupationally exposed human individuals...
Web-enabled medical databases: a threat to security?J Herrin
National Institute of Public Health, Oslo, Norway
Methods Inf Med 39:298-302. 2000..The evidence, though limited, suggests that the additional risk may be small relative to more traditional security threats...
[Home accidents among small children and preventive potential]I Myklestad
Avdeling for samfunnsmedisin Statens institutt for folkehelse Postboks 4404 Torshov 0403 Oslo
Tidsskr Nor Laegeforen 120:3376-9. 2000..The incidence of childhood home injuries is currently high. A portion of these injuries could be prevented by simple safety precautions...
IgE adjuvant effect caused by particles - immediate and delayed effectsB Granum
Department of Environmental Medicine, National Institute of Public Health, P O Box 4404 Nydalen, Torshov, N 0403 Oslo, Norway
Toxicology 156:149-59. 2001..These findings imply that individuals exposed to particulate air pollution at one point of time may develop an increased reaction towards allergens inhaled later that day or even several days after the particle exposure...
[Attitude of pregnant women to routine voluntary antenatal HIV testing]B M Kvam
Seksjon for forebyggende infeksjonsmedisin Statens institutt for folkehelse Postboks 4404 Torshov 0403 Oslo
Tidsskr Nor Laegeforen 120:2895-900. 2000..Since 1987, more than 95% of pregnant Norwegian women have accepted the offer of an antenatal HIV test. We investigated women's opinion regarding antenatal HIV testing...
In vivo growth inhibition of human colon carcinoma cells (HT-29) by all-trans-retinoic acid, difluoromethylornithine, and colon mitosis inhibitor, individually and in combinationJ E Paulsen
Department of Environmental Medicine, National Institute of Public Health, PO Box 4404, Torshov, N 0403, Oslo, Norway
Anticancer Res 20:3485-9. 2000..We studied the combination of all-trans-retinoic acid (RA), difluoromethylornithine (DFMO) and the tripeptide colon mitosis inhibitor (CMI) on the in vivo growth of human colon carcinoma cells (HT-29) in athymic mice...
Streptococcus pneumoniae heat shock protein 70 does not induce human antibody responses during infectionJ Kolberg
Department of Vaccinology, National Institute of Public Health, Torshov, Oslo, Norway
FEMS Immunol Med Microbiol 29:289-94. 2000..The human sera contained antibodies to high molecular proteins co-purified with hsp70. Some of these proteins could be the pneumococcal surface protein A...
Human T-cell lymphotropic virus testing of blood donors in Norway: a cost-effect modelH Stigum
Department of Population Health Sciences, National Institute of Public Health, Oslo, Norway
Int J Epidemiol 29:1076-84. 2000..Antibody tests from 5.5 million European blood donors have shown that the HTLV prevalence is low, ranging from 0 to 0.02%. This paper examines costs and effects associated with the intervention of testing all new blood donors for HTLV...
Suspended particulate matter in indoor air: adjuvants and allergen carriersH Ormstad
Department of Environmental Medicine, National Institute of Public Health, PO Box 4404, Torshov N 0403, Oslo, Norway
Toxicology 152:53-68. 2000..Furthermore, SPM was found to elicit a local lymph node inflammatory response, and to have an adjuvant activity on the production of IgE antibodies to ovalbumin (OA)...
IgG antibody levels to meningococcal porins in patient sera: comparison of immunoblotting and ELISA measurementsE Wedege
Department of Vaccinology, National Institute of Public Health, P O Box 4404, Torshov, N 0403, Oslo, Norway
J Immunol Methods 244:9-15. 2000..However, blotting at a higher serum dilution (1/2000) resulted in anti-PorB levels that also correlated strongly (r(s)=0.93 P<0.001) with the ELISA measurements...
Daycare attendance, asthma and atopyW Nystad
Department of Population Health Sciences, National Institute of Public Health, and the University of Sport and Physical Education, Oslo, Norway
Ann Med 32:390-6. 2000..The quality of the studies varies, and they are not directly comparable. The relation between daycare attendance and asthma and atopy is unclear, and further studies designed to answer this specific research question are needed...
Functional activities and epitope specificity of human and murine antibodies against the class 4 outer membrane protein (Rmp) of Neisseria meningitidisE Rosenqvist
Department of Vaccinology, National Institute of Public Health, N 0403 Oslo, Norway
Infect Immun 67:1267-76. 1999....
