Genomes and Genes
Affiliation: Institute for Cancer Research
- Mouse Tcf3 represses canonical Wnt signaling by either competing for β-catenin binding or through occupation of DNA-binding sitesNina Solberg
SFI CAST Biomedical Innovation Center, Unit for Cell Signaling, Oslo University Hospital, Forskningsparken, Gaustadalleen 21, 0349 Oslo, Norway
Mol Cell Biochem 365:53-63. 2012..A direct physical interaction between β-catenin and Tcf3 in the nucleus was confirmed by co-immunoprecipitation studies. The inhibitory β-catenin/Tcf3 interface was independent of the ability of Tcf3 to directly interact with DNA...
- Effect of canonical Wnt inhibition in the neurogenic cortex, hippocampus, and premigratory dentate gyrus progenitor poolNina Solberg
Section for Cellular and Genetic Therapy, Institute of Microbiology, Rikshospitalet, Oslo, Norway
Dev Dyn 237:1799-811. 2008..The lower number of progenitors in the dentate gyrus was not rescued after migration to the subgranular zone and thus the dentate gyrus lacked the entire internal blade and a part of the external blade from postnatal to adult stages...
- Characterization and functional analysis of the 5'-flanking promoter region of the mouse Tcf3 geneNina Solberg
Department of Microbiology, Oslo University Hospital, Rikshospitalet, Forskningsparken, Oslo, Norway
Mol Cell Biochem 360:289-99. 2012..In vivo analysis of a 4.5 kb promoter fragment (-4303/+211) driving, the expression of EGFP in mouse embryos highly resembled endogenous expression of mTcf3...