Jorrit M Enserink

Summary

Affiliation: Institute for Cancer Research
Country: Norway

Publications

  1. doi request reprint Chemical genetics: budding yeast as a platform for drug discovery and mapping of genetic pathways
    Jorrit M Enserink
    Department of Molecular Biology, Institute of Medical Microbiology and Centre for Molecular Biology and Neuroscience, Oslo University Hospital, Sognsvannsveien 20, NO 0027 Oslo, Norway
    Molecules 17:9258-73. 2012
  2. pmc What makes the engine hum: Rad6, a cell cycle supercharger
    Jorrit M Enserink
    Department of Molecular Biology, Institute of Medical Microbiology and Centre of Molecular Biology and Neuroscience, Oslo University Hospital, Oslo, Norway
    Cell Cycle 11:249-52. 2012
  3. pmc An overview of Cdk1-controlled targets and processes
    Jorrit M Enserink
    Department of Molecular Biology, Institute of Medical Microbiology and Centre of Molecular Biology and Neuroscience, Oslo University Hospital, Sognsvannsveien 20, N 0027 Oslo, Norway
    Cell Div 5:11. 2010
  4. doi request reprint TORC1 inhibits GSK3-mediated Elo2 phosphorylation to regulate very long chain fatty acid synthesis and autophagy
    Christine Zimmermann
    Department of Microbiology, Oslo University Hospital, and University of Oslo, 0027 Oslo, Norway
    Cell Rep 5:1036-46. 2013
  5. pmc Cdc28 kinase activity regulates the basal transcription machinery at a subset of genes
    Pierre Chymkowitch
    Department of Molecular Biology, Institute of Microbiology, and Centre for Molecular Biology and Neuroscience, Oslo University Hospital, Sognsvannsveien 20, NO 0027 Oslo, Norway
    Proc Natl Acad Sci U S A 109:10450-5. 2012
  6. pmc A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression
    Christine Zimmermann
    Department of Molecular Biology, Institute of Medical Microbiology and Centre of Molecular Biology and Neuroscience, Oslo University Hospital, N 0027 Oslo, Norway
    Proc Natl Acad Sci U S A 108:18748-53. 2011
  7. pmc Sumoylation of Rap1 mediates the recruitment of TFIID to promote transcription of ribosomal protein genes
    Pierre Chymkowitch
    Institute of Microbiology, Clinic for Diagnostics and Intervention, Oslo University Hospital, N 0027 Oslo, Norway University of Oslo, 0316 Oslo, Norway
    Genome Res 25:897-906. 2015
  8. pmc The cell cycle rallies the transcription cycle: Cdc28/Cdk1 is a cell cycle-regulated transcriptional CDK
    Pierre Chymkowitch
    Department of Molecular Biology, Institute of Medical Microbiology and Centre for Molecular Biology and Neuroscience, Oslo University Hospital, Oslo, Norway
    Transcription 4:3-6. 2013
  9. doi request reprint SUMO-regulated transcription: challenging the dogma
    Pierre Chymkowitch
    Department of Molecular Biology, Institute of Microbiology, Oslo University Hospital, Oslo, Norway
    Bioessays 37:1095-105. 2015

Collaborators

  • Howard Riezman
  • Christopher D Putnam
  • Yves Barral
  • Pierre Chymkowitch
  • Christine Zimmermann
  • Magnar Bjørås
  • Susanne Lorenz
  • Leonardo A Meza-Zepeda
  • Jessica M Lindvall
  • Vegard Eldholm
  • Håvard Aanes
  • Bernd Thiede
  • Arne Klungland
  • Aurélie Nguéa P
  • Aurélie P Nguéa
  • Christian J Koehler
  • Charulatha Gururaj
  • Lorena Clay
  • Nils J Færgeman
  • Teresa M Dunn
  • Aline Santos
  • Dennis Pultz
  • Kenneth Gable
  • Steven V Rødkær
  • Amy Chang
  • Sharon Epstein
  • Richard D Kolodner
  • Manja Omerzu

Detail Information

Publications9

  1. doi request reprint Chemical genetics: budding yeast as a platform for drug discovery and mapping of genetic pathways
    Jorrit M Enserink
    Department of Molecular Biology, Institute of Medical Microbiology and Centre for Molecular Biology and Neuroscience, Oslo University Hospital, Sognsvannsveien 20, NO 0027 Oslo, Norway
    Molecules 17:9258-73. 2012
    ..Here, I review some of the recent developments in chemical-genetic techniques in budding yeast...
  2. pmc What makes the engine hum: Rad6, a cell cycle supercharger
    Jorrit M Enserink
    Department of Molecular Biology, Institute of Medical Microbiology and Centre of Molecular Biology and Neuroscience, Oslo University Hospital, Oslo, Norway
    Cell Cycle 11:249-52. 2012
    ..Thus, Rad6 boosts the activity of the cell cycle machinery...
  3. pmc An overview of Cdk1-controlled targets and processes
    Jorrit M Enserink
    Department of Molecular Biology, Institute of Medical Microbiology and Centre of Molecular Biology and Neuroscience, Oslo University Hospital, Sognsvannsveien 20, N 0027 Oslo, Norway
    Cell Div 5:11. 2010
    ..In this review we discuss currently known targets of Cdk1 in the budding yeast S. cerevisiae and highlight the role of Cdk1 in several crucial processes including maintenance of genome stability...
  4. doi request reprint TORC1 inhibits GSK3-mediated Elo2 phosphorylation to regulate very long chain fatty acid synthesis and autophagy
    Christine Zimmermann
    Department of Microbiology, Oslo University Hospital, and University of Oslo, 0027 Oslo, Norway
    Cell Rep 5:1036-46. 2013
    ..Together, our data reveal a function for TORC1 and GSK3 in the regulation of VLCFA synthesis that has important implications for autophagy and cell homeostasis...
  5. pmc Cdc28 kinase activity regulates the basal transcription machinery at a subset of genes
    Pierre Chymkowitch
    Department of Molecular Biology, Institute of Microbiology, and Centre for Molecular Biology and Neuroscience, Oslo University Hospital, Sognsvannsveien 20, NO 0027 Oslo, Norway
    Proc Natl Acad Sci U S A 109:10450-5. 2012
    ..Our results reveal a mechanism of cell-cycle-dependent regulation of basal transcription...
  6. pmc A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression
    Christine Zimmermann
    Department of Molecular Biology, Institute of Medical Microbiology and Centre of Molecular Biology and Neuroscience, Oslo University Hospital, N 0027 Oslo, Norway
    Proc Natl Acad Sci U S A 108:18748-53. 2011
    ..These results link cellular ubiquitin levels and the Rad6-Bre1 pathway to cell cycle progression...
  7. pmc Sumoylation of Rap1 mediates the recruitment of TFIID to promote transcription of ribosomal protein genes
    Pierre Chymkowitch
    Institute of Microbiology, Clinic for Diagnostics and Intervention, Oslo University Hospital, N 0027 Oslo, Norway University of Oslo, 0316 Oslo, Norway
    Genome Res 25:897-906. 2015
    ..Taken together, Sumo regulates the cellular translational capacity by promoting transcription of tRNA genes and RPGs. ..
  8. pmc The cell cycle rallies the transcription cycle: Cdc28/Cdk1 is a cell cycle-regulated transcriptional CDK
    Pierre Chymkowitch
    Department of Molecular Biology, Institute of Medical Microbiology and Centre for Molecular Biology and Neuroscience, Oslo University Hospital, Oslo, Norway
    Transcription 4:3-6. 2013
    ..Here, we discuss the biological significance of this finding and give our view of the kinase-dependent role of Cdc28 in regulation of RNA polymerase II...
  9. doi request reprint SUMO-regulated transcription: challenging the dogma
    Pierre Chymkowitch
    Department of Molecular Biology, Institute of Microbiology, Oslo University Hospital, Oslo, Norway
    Bioessays 37:1095-105. 2015
    ..However, as we will discuss in this review, this model needs to be refined, because recent studies have revealed that SUMO can also have profound positive effects on transcription. ..